Non-invasive monitoring of L-2-oxothiazolidine-4-carboxylate metabolism in the rat brain by in vivo 13C magnetic resonance spectroscopy

Neurochemical Research

Volumn 36, Issue 3, 2011, Pages 443-451

  Gamcsik, Michael P ^a   Clark, M Daniel ^b   Ludeman, Susan M ^c   Springer, James B ^d   D'Alessandro, Michael A ^c   Simpson, Nicholas E ^b   Pourdeyhimi, Roxana ^a   Johnson, C Bryce ^a   Teeter, Stephanie D ^a   Blackband, Stephen J ^b   Thelwall, Peter E ^e  

^a USA and North Carolina State University   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c ALBANY COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Cysteine; Glutathione; Magnetic resonance; Metabolism; Taurine

Indexed keywords

2 OXO 4 THIAZOLIDINECARBOXYLIC ACID; CARBON 13; CYSTEINE; GLUTATHIONE; HYPOTAURINE; LACTIC ACID; TAURINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG CLEARANCE; DRUG METABOLISM; DRUG UPTAKE; EX VIVO STUDY; FEMALE; IN VIVO STUDY; ISOTOPE LABELING; MASS SPECTROMETRY; MONITORING; NON INVASIVE MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; FEMALE; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATIVE STRESS; PYRROLIDONECARBOXYLIC ACID; RATS; RATS, INBRED F344; THIAZOLIDINES;

RATTUS;

EID: 79954415786     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-010-0362-5     Document Type: Article

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