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Volumn 35, Issue 1, 2011, Pages 45-54

Impact of laboratory testing for heparin-induced antibodies: Using Bayes' rule to prevent overdiagnosis of heparin-induced thrombocytopenia

Author keywords

Bayes; heparin induced platelet activation (HIPA) test; heparin induced thrombocytopenia (HIT); platelet factor 4 (PF4); thrombocytopenia; thrombosis

Indexed keywords

ADENOSINE DIPHOSPHATE; HEPARIN; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; THROMBOCYTE FACTOR 4;

EID: 79953896673     PISSN: 03423026     EISSN: 14390477     Source Type: Journal    
DOI: 10.1515/JLM.2010.019     Document Type: Article
Times cited : (2)

References (36)
  • 1
    • 85131246527 scopus 로고    scopus 로고
    • Frequency of heparin-induced thrombocytopenia
    • Warkentin TE, Greinacher A, editors (4th edition) New York: Informa Healthcare USA
    • Lee DH, Warkentin TE. Frequency of heparin-induced thrombocytopenia. In: Warkentin TE, Greinacher A, editors. Heparin-induced thrombocytopenia (4th edition). New York: Informa Healthcare USA, 2007:67-116.
    • (2007) Heparin-induced Thrombocytopenia , pp. 67-116
    • Lee, D.H.1    Warkentin, T.E.2
  • 2
    • 0142258733 scopus 로고    scopus 로고
    • Management of heparin-induced thrombocytopenia: A critical comparison of lepirudin and argatroban
    • DOI 10.1016/S0049-3848(03)00336-0
    • Warkentin TE. Management of heparin-induced thrombocytopenia: a critical comparison of lepirudin and argatroban. Thromb Res 2003;110:73-82. (Pubitemid 37329444)
    • (2003) Thrombosis Research , vol.110 , Issue.2-3 , pp. 73-82
    • Warkentin, T.E.1
  • 3
    • 36749095644 scopus 로고    scopus 로고
    • What is the potential for overdiagnosis of heparin-induced thrombocytopenia?
    • DOI 10.1002/ajh.21032
    • Lo GK, Sigouin CS, Warkentin TE. What is the potential for overdiagnosis of heparin-induced thrombocytopenia? Am J Hematol 2007;82:1037-43. (Pubitemid 350209843)
    • (2007) American Journal of Hematology , vol.82 , Issue.12 , pp. 1037-1043
    • Lo, G.K.1    Sigouin, C.S.2    Warkentin, T.E.3
  • 4
    • 34447617364 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: A prospective study on the incidence, platelet-activating capacity and clinical significance of antiplatelet factor 4/heparin antibodies of the IgG, IgM, and IgA classes
    • DOI 10.1111/j.1538-7836.2007.02617.x
    • Greinacher A, Juhl D, Strobel U, Wessel A, Lubenow N, Selleng K, et al. Heparin-induced thrombocytopenia: a prospective study on the incidence, platelet-activating capacity and clinical significance of anti-PF4/heparin antibodies of the IgG, IgM, and IgA classes. J Thromb Haemost 2007;5:1666-73. (Pubitemid 47091409)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.8 , pp. 1666-1673
    • Greinacher, A.1    Juhl, D.2    Strobel, U.3    Wessel, A.4    Lubenow, N.5    Selleng, K.6    Eichler, P.7    Warkentin, T.E.8
  • 5
    • 0022640930 scopus 로고
    • A Diagnostic test for heparin-induced thrombocytopenia
    • Sheridan D, Carter C, Kelton JG. A diagnostic test for heparin-induced thrombocytopenia. Blood 1986;67:27-30. (Pubitemid 16167006)
    • (1986) Blood , vol.67 , Issue.1 , pp. 27-30
    • Sheridan, D.1    Carter, C.2    Kelton, J.G.3
  • 6
    • 0031963059 scopus 로고    scopus 로고
    • Adenosine diphosphate (ADP) and ADP receptor play a major role in platelet activation/aggregation induced by sera from heparin-induced thrombocytopenia patients
    • Polgar J, Eichler P, Greinacher A, Clemetson KJ. Adenosine diphosphate (ADP) and ADP receptor play a major role in plate- let activation/aggregation induced by sera from heparin-induced thrombocytopenia patients. Blood 1998;91:549-54. (Pubitemid 28053377)
    • (1998) Blood , vol.91 , Issue.2 , pp. 549-554
    • Polgar, J.1    Eichler, P.2    Greinacher, A.3    Clemetson, K.J.4
  • 7
    • 33748893828 scopus 로고    scopus 로고
    • Testing for heparin-induced thrombocytopenia antibodies
    • DOI 10.1016/j.tmrv.2006.05.001, PII S0887796306000290
    • Warkentin TE, Sheppard JA. Testing for heparin-induced thrombocytopenia antibodies. Transfus Med Rev 2006;20:259-72. (Pubitemid 44428106)
    • (2006) Transfusion Medicine Reviews , vol.20 , Issue.4 , pp. 259-272
    • Warkentin, T.E.1    Sheppard, J.A.2
  • 8
    • 0025951938 scopus 로고
    • A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia
    • Greinacher A, Michels I, Kiefel V, Mueller-Eckhardt C. A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia. Thromb Haemost 1991;66:734-6.
    • (1991) Thromb Haemost , vol.66 , pp. 734-6
    • Greinacher, A.1    Michels, I.2    Kiefel, V.3    Mueller-Eckhardt, C.4
  • 9
    • 0032834309 scopus 로고    scopus 로고
    • Generation of platelet-derived microparticles and procoagulant activity by heparin-induced thrombocytopenia IgG/serum and other IgG platelet agonists: A comparison with standard platelet agonists
    • DOI 10.1080/09537109975960
    • Warkentin TE, Sheppard JI. Generation of platelet-derived microparticles and procoagulant activity by heparin-induced thrombocytopenia IgG/serum and other IgG platelet agonists: a comparison with standard platelet agonists. Platelets 1999;10: 319-26. (Pubitemid 29490859)
    • (1999) Platelets , vol.10 , Issue.5 , pp. 319-326
    • Warkentin, T.E.1    Sheppard, J.I.2
  • 11
    • 0035953702 scopus 로고    scopus 로고
    • Temporal aspects of heparin-induced thrombocytopenia
    • DOI 10.1056/NEJM200104263441704
    • Warkentin TE, Kelton JG. Temporal aspects of heparin-induced thrombocytopenia. N Engl J Med 2001;344:1286-92. (Pubitemid 32372963)
    • (2001) New England Journal of Medicine , vol.344 , Issue.17 , pp. 1286-1292
    • Warkentin, T.E.1    Kelton, J.G.2
  • 13
    • 0026646478 scopus 로고
    • Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia
    • Warkentin TE, Hayward CP, Smith CA, Kelly PM, Kelton JG. Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia. J Lab Clin Med 1992;120: 371-9.
    • (1992) J Lab Clin Med , vol.120 , pp. 371-9
    • Warkentin, T.E.1    Hayward, C.P.2    Smith, C.A.3    Kelly, P.M.4    Kelton, J.G.5
  • 14
    • 49849104673 scopus 로고    scopus 로고
    • An algorithm for resolving 'indeterminate' test results in the platelet serotonin release assay for investigation of heparin-induced thrombocytopenia
    • Moore JC, Arnold DM, Warkentin TE, Warkentin AE, Kelton JG. An algorithm for resolving 'indeterminate' test results in the platelet serotonin release assay for investigation of heparin-induced thrombocytopenia. J Thromb Haemost 2008;6:1595-7.
    • (2008) J Thromb Haemost , vol.6 , pp. 1595-7
    • Moore, J.C.1    Arnold, D.M.2    Warkentin, T.E.3    Warkentin, A.E.4    Kelton, J.G.5
  • 15
    • 45949112509 scopus 로고    scopus 로고
    • Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays
    • DOI 10.1111/j.1538-7836.2008.03025.x
    • Warkentin TE, Sheppard JI, Moore JC, Sigouin CS, Kelton JG. Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays. J Thromb Haemost 2008;6:1304-12. (Pubitemid 352016309)
    • (2008) Journal of Thrombosis and Haemostasis , vol.6 , Issue.8 , pp. 1304-1312
    • Warkentin, T.E.1    Sheppard, J.I.2    Moore, J.C.3    Sigouin, C.S.4    Kelton, J.G.5
  • 16
    • 0037610515 scopus 로고    scopus 로고
    • An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patients
    • DOI 10.1001/archinte.163.20.2518
    • Warkentin TE, Roberts RS, Hirsh J, Kelton JG. An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patients. Arch Intern Med 2003;163: 2518-24. (Pubitemid 37385796)
    • (2003) Archives of Internal Medicine , vol.163 , Issue.20 , pp. 2518-2524
    • Warkentin, T.E.1    Roberts, R.S.2    Hirsh, J.3    Kelton, J.G.4
  • 19
    • 0026638091 scopus 로고
    • Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia
    • Amiral J, Bridey F, Dreyfus M, Vissoc AM, Fressinaud E, Wolf M, et al. Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Thromb Haemost 1992;68:95-6.
    • (1992) Thromb Haemost , vol.68 , pp. 95-6
    • Amiral, J.1    Bridey, F.2    Dreyfus, M.3    Vissoc, A.M.4    Fressinaud, E.5    Wolf, M.6
  • 20
    • 0028014541 scopus 로고
    • Heparin-associated thrombocytopenia: Isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen
    • Greinacher A, Potzsch B, Amiral J, Dummel V, Eichner A, Mueller-Eckhardt C. Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen. Thromb Haemost 1994;71:247-51. (Pubitemid 24047336)
    • (1994) Thrombosis and Haemostasis , vol.71 , Issue.2 , pp. 247-251
    • Greinacher, A.1    Potzsch, B.2    Amiral, J.3    Dummel, V.4    Eichner, A.5    Mueller-Eckhardt, C.6
  • 21
    • 67949124723 scopus 로고    scopus 로고
    • Prospective evaluation of immunoassays for the diagnosis of heparin-induced thrombocytopenia
    • Bakchoul T, Giptner A, Bein G, Santoso S, Sachs UJ. Prospective evaluation of immunoassays for the diagnosis of heparin-induced thrombocytopenia. J Thromb Haemost 2009;7: 1260-5.
    • (2009) J Thromb Haemost , vol.7 , pp. 1260-5
    • Bakchoul, T.1    Giptner, A.2    Bein, G.3    Santoso, S.4    Sachs, U.J.5
  • 23
    • 0034937429 scopus 로고    scopus 로고
    • Determination of heparin-platelet factor 4-IgG antibodies improves diagnosis of heparin-induced thrombocytopenia
    • DOI 10.1046/j.1365-2141.2001.02869.x
    • Lindhoff-Last E, Gerdsen F, Ackermann H, Bauersachs R. Determination of heparin-platelet factor 4-IgG antibodies improves diagnosis of heparin-induced thrombocytopenia. Br J Haematol 2001;113:886-90. (Pubitemid 32634754)
    • (2001) British Journal of Haematology , vol.113 , Issue.4 , pp. 886-890
    • Lindhoff-Last, E.1    Gerdsen, F.2    Ackermann, H.3    Bauersachs, R.4
  • 25
    • 79953837683 scopus 로고    scopus 로고
    • Use of well-characterized sera for assessment of new diagnostic enzyme-immunoassays for diagnosis of heparin-induced thrombocytopenia
    • Oct 10. [Epub ahead of print]
    • Warkentin TE, Sheppard JI, Moore JC, Kelton JG. Use of well-characterized sera for assessment of new diagnostic enzyme-immunoassays for diagnosis of heparin-induced thrombocytopenia. J Thromb Haemost 2009 Oct 10. [Epub ahead of print].
    • (2009) J Thromb Haemost
    • Warkentin, T.E.1    Sheppard, J.I.2    Moore, J.C.3    Kelton, J.G.4
  • 27
    • 33644610355 scopus 로고    scopus 로고
    • No significant improvement in diagnostic specificity of an anti-PF4/polyanion immunoassay with use of high heparin confirmatory procedure
    • Warkentin TE, Sheppard JI. No significant improvement in diagnostic specificity of an anti-PF4/polyanion immunoassay with use of high heparin confirmatory procedure. J Thromb Haemost 2006;4:281-2.
    • (2006) J Thromb Haemost , vol.4 , pp. 281-2
    • Warkentin, T.E.1    Sheppard, J.I.2
  • 28
    • 33644971524 scopus 로고    scopus 로고
    • Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings
    • Lo GK, Juhl D, Warkentin TE, Sigouin CS, Eichler P, Grei-nacher A. Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings. J Thromb Haemost 2006;4:759-65.
    • (2006) J Thromb Haemost , vol.4 , pp. 759-65
    • Lo, G.K.1    Juhl, D.2    Warkentin, T.E.3    Sigouin, C.S.4    Eichler, P.5    Grei-Nacher, A.6
  • 29
    • 0029035681 scopus 로고
    • Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin
    • Warkentin TE, Levine MN, Hirsh J, Horsewood P, Roberts RS, Gent M, et al. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 1995;332:1330-5.
    • (1995) N Engl J Med , vol.332 , pp. 1330-5
    • Warkentin, T.E.1    Levine, M.N.2    Hirsh, J.3    Horsewood, P.4    Roberts, R.S.5    Gent, M.6
  • 32
    • 85131238641 scopus 로고    scopus 로고
    • Clinical picture of heparin-induced thrombocytopenia
    • Warkentin TE, Greinacher A, editors 4th ed New York: Informa Healthcare USA
    • Warkentin TE. Clinical picture of heparin-induced thrombocytopenia. In: Warkentin TE, Greinacher A, editors. Heparin-induced thrombocytopenia, 4th ed. New York: Informa Healthcare USA, 2007:21-66.
    • (2007) Heparin-induced Thrombocytopenia , pp. 21-66
    • Warkentin, T.E.1
  • 33
    • 0035899952 scopus 로고    scopus 로고
    • Venous limb gangrene during warfarin treatment of cancer-associated deep venous thrombosis
    • Warkentin TE. Venous limb gangrene during warfarin treatment of cancer-associated deep venous thrombosis. Ann Intern Med 2001;135:589-93. (Pubitemid 33010194)
    • (2001) Annals of Internal Medicine , vol.135 , Issue.8 II , pp. 589-593
    • Warkentin, T.E.1
  • 34
    • 85131258180 scopus 로고    scopus 로고
    • Pseudo-heparin-induced thrombocytopenia
    • Warkentin TE, Greinacher A, editors 4th ed New York: Informa Healthcare USA Inc
    • Warkentin TE. Pseudo-heparin-induced thrombocytopenia. In: Warkentin TE, Greinacher A, editors. Heparin-induced thrombocytopenia, 4th ed. New York: Informa Healthcare USA Inc., 2007:261-82.
    • (2007) Heparin-induced Thrombocytopenia , pp. 261-82
    • Warkentin, T.E.1
  • 35
    • 79953872522 scopus 로고    scopus 로고
    • A prospective study of platelet count changes and HIT antibodies in post-cardiac surgery patients: Early-onset and persisting thrombocytopenia is rarely due to HIT
    • Sep 28. [Epub ahead of print]
    • Selleng S, Malowsky B, Strobel U, Wessel A, Itterman T, Wollert HG, et al. A prospective study of platelet count changes and HIT antibodies in post-cardiac surgery patients: early-onset and persisting thrombocytopenia is rarely due to HIT. J Thromb Haemost 2009 Sep 28. [Epub ahead of print].
    • (2009) J Thromb Haemost
    • Selleng, S.1    Malowsky, B.2    Strobel, U.3    Wessel, A.4    Itterman, T.5    Wollert, H.G.6


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