Key role of water-insoluble allergens of pollen cytoplasmic granules in biased allergic response in a rat model

World Allergy Organization Journal

Volumn 4, Issue 1, 2011, Pages 4-12

  Chakra, Oussama R Abou ^a   Sutra, Jean Pierre ^a   Poncet, Pascal ^a,b   Lacroix, Ghislaine ^c   Sénéchal, Hélène ^a,d  

^a PSL RESEARCH UNIVERSITY   (France)

^b INSTITUT PASTEUR   (France)

^c DRC   (France)

^d INSERM   (France)

Author keywords

Allergenicity; Grass pollen; IgE; Pollen cytoplasmic granules; Water insoluble allergens; Water soluble allergens

Indexed keywords

ALLERGEN; CYTOKINE; GRASS POLLEN EXTRACT; IMMUNOGLOBULIN E;

ALLERGENICITY; ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL GRANULE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; GRASS POLLEN; HUMAN; HUMORAL IMMUNITY; IMMUNOBLOTTING; LOCAL LYMPH NODE ASSAY; LUNG ALVEOLUS CELL; LUNG LAVAGE; LYMPH NODE CELL; LYMPHOCYTE; MALE; NONHUMAN; PHLEUM PRATENSE; PRIORITY JOURNAL; RAT;

EID: 79953845462     PISSN: 19394551     EISSN: None     Source Type: Journal    
DOI: 10.1097/WOX.0b013e318205ab44     Document Type: Article

References (50)

1. Lacroix G. Allergies respiratoires, pollens et polluants. Arch Mal Prof Environ. 2005;66:584 -591. (Pubitemid 44194697)
2. Singh MB, Hough T, Theerakulpisut P, Avjioglu A, Davies S, et al. Isolation of cDNA encoding a newly identified major allergenic protein of rye-grass pollen: Intracellular targeting to the amyloplast. Proc Natl Acad Sci U S A. 1991;88:1384 -1388. (Pubitemid 21916228)
3. Suphioglu C. Thunderstorm asthma due to grass pollen. Int Arch Allergy Immunol. 1998;116:253-260. (Pubitemid 28359248)
4. Schappi GF, Taylor PE, Staff IA, Rolland JM, Suphioglu C. Immunologic significance of respirable atmospheric starch granules containing major birch allergen Bet v 1. Allergy. 1999;54:478-483. (Pubitemid 29244188)
5. Motta AC, Marliere M, Peltre G, Sterenberg PA, Lacroix G. Trafficrelated air pollutants induce the release of allergen-containing cytoplasmic granules from grass pollen. Int Arch Allergy Immunol. 2006;139: 294-298.
6. Suphioglu C, Singh MB, Taylor P, Bellomo R, Holmes P, Puy R, Knox RB. Mechanism of grass-pollen-induced asthma. Lancet. 1992;339(8793):569- 572.
7. Abou Chakra OR, Sutra JP, Rogerieux F, Peltre G, Sénéchal H, Lacroix G. Immunological interactive effects between pollen grains and their cytoplasmic granules on Brown Norway rats. WAO J. 2009;2:201-207.
8. Bacsi A, Choudhury BK, Dharajiya N, Sur S, Boldogh I. Subpollen particles: Carriers of allergenic proteins and oxidases. J Allergy Clin Immunol. 2006;118:844-850. (Pubitemid 44498755)
9. Motta A, Peltre G, Dormans JA, Withagen CE, Lacroix G, Bois F, Steerenberg PA. Phleum pratense pollen starch granules induce humoral and cell-mediated immune responses in a rat model of allergy. Clin Exp Allergy. 2004;34:310 -314. (Pubitemid 38315269)
10. Motta AC, Dormans JA, Peltre G, Lacroix G, Bois FY, Steerenberg PA. Intratracheal instillation of cytoplasmic granules from Phleum pratense pollen induces IgE- and cell-mediated responses in the Brown Norway rat. Int Arch Allergy Immunol. 2004;135:24 -29. (Pubitemid 39279427)
11. Currie AJ, Stewart GA, McWilliam AS. Alveolar macrophages bind and phagocytose allergen-containing pollen starch granules via C-type lectin and integrin receptors: implications for airway inflammatory disease. J Immunol. 2000;164:3878 -3886. (Pubitemid 30169847)
12. Fischer S, Grote M, Fahlbusch B, Müller WD, Kraft D, Valenta R. Characterization of Phl p 4, a major timothy grass (Phleum pratense) pollen allergen. J Allergy Clin Immunol. 1996;98:189 -198. (Pubitemid 26289402)
13. Grote M, Dolecek C, Van Ree R, Valenta R. Immunogold electron microscopic localization of timothy grass (Phleum pratense) pollen major allergens Phl p I and Phl p V after anhydrous fixation in acrolein vapor. J Histochem Cytochem. 1994;42:427- 431. (Pubitemid 24064488)
14. Grote M, Swoboda I, Valenta R, Reichelt R. Group 13 allergens as environmental and immunological markers for grass pollen allergy: studies by immunogold field emission scanning and transmission electron microscopy. Int Arch Allergy Immunol. 2005;136:303-310. (Pubitemid 41094493)
15. Taylor PE, Staff IA, Singh MB, Knox RB. Localization of the two major allergens in rye-grass pollen using specific monoclonal antibodies and quantitative analysis of immunogold labelling. Histochem J. 1994;26: 392-401. (Pubitemid 24171682)
16. Vrtala S, Fischer S, Grote M, Vangelista L, Pastore A, et al. Molecular, immunological, and structural characterization of Phl p 6, a major allergen and P-particle-associated protein from Timothy grass (Phleum pratense) pollen. J Immunol. 1999;163:5489 -5496.
17. Bittner C, Grassau B, Frenzel K, Baur X. Identification of wheat gliadins as an allergen family related to baker's asthma. J Allergy Clin Immunol. 2008;121:744 -749. (Pubitemid 351323854)
18. Yeang HY, Arif SA, Yusof F, Sunderasan E. Allergenic proteins of natural rubber latex. Methods. 2002;27:32- 45. (Pubitemid 34757067)
19. Bice DE, Seagrave J, Green FH. Animal models of asthma: potential usefulness for studying health effects of inhaled particles. Inhal Toxicol. 2000;12:829-862.
20. Boverhof DR, Billington R, Gollapudi BB, Hotchkiss JA, Krieger SM, et al. Respiratory sensitization and allergy: current research approaches and needs. Toxicol Appl Pharmacol. 2008;226:1-13. (Pubitemid 350235585)
21. Steerenberg PA, Dormans JA, van Doorn CC, Middendorp S, Vos JG, van Loveren H. A pollen model in the rat for testing adjuvant activity of air pollution components. Inhal Toxicol. 1999;11:1109 -1122. (Pubitemid 30023324)
22. Szelenyi I. Animal models of bronchial asthma. Inflamm Res. 2000;49: 639-654. (Pubitemid 32097079)
23. Batard T, Basuyaux B, Lambin P, Brémard-Oury C, Hamilton RG, David B, Peltre G. Isotypic analysis of grass pollen-specific immunoglobulins in human plasma. 1. Specialization of certain classes and subclasses in the immune response. Int Arch Allergy Immunol. 1993;100:68-78. (Pubitemid 23067872)
24. Mahler V, Diepgen TL, Kubeta O, Leakakos T, Truscott W, et al. Mutual boosting effects of sensitization with timothy grass pollen and latex glove extract on IgE antibody responses in a mouse model. J Invest Dermatol. 2000;114:1039 -1043. (Pubitemid 30252729)
25. Rogerieux F, Godfrin D, Sénéchal H, Motta AC, Marlière M, Peltre G, Lacroix G. Modifications of Phleum pratense grass pollen allergens following artificial exposure to gaseous air pollutants (O 3, NO 2, SO 2). Int Arch Allergy Immunol. 2007;143:127-134. (Pubitemid 46742349)
26. Godfrin D, Senechal H, Sutra JP, Busnel JM, Desvaux FX, Peltre G. A modified enzyme-linked immunosorbent assay adapted for immunodetection of low amounts of water-insoluble proteins. J Immunol Methods. 2007;326:83-92. (Pubitemid 47361199)
27. Abou Chakra O, Rogerieux F, Poncet P, Sutra JP, Peltre G, Sénéchal H, Lacroix G. Ability of pollen cytoplasmic granules to induce biased allergic responses in rat model. Int Arch Allergy Immunol. 2010;154: 128-136.
28. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265-275.
29. Sénéchal H, Mayer C, Le Mao J, et al. Two-dimensional immunoblot analysis of non-water soluble grass pollen allergens. XXII Congress EAACI - Abstract Book. 2003:382.
30. Su SN, Harris J, Lau GX, Han SH. Aqueous-organic solvent extraction of water-insoluble protein from ragweed pollen. Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1987;20:104 -112.
31. Su SN, Lau GX, Harris J. Isolation and characterization of a newly identified antigen from ragweed pollen by organic solvent extraction. Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1985;18: 157-168.
32. Würtzen PA, van Neerven RJ, Arnved J, Ipsen H, Sparholt SH. Dissection of the grass allergen-specific immune response in patients with allergies and control subjects: T-cell proliferation in patients does not correlate with specific serum IgE and skin reactivity. J Allergy Clin Immunol. 1998;101:241-249.
33. Hope JC, Dearman RJ, Kimber I, Hopkins SJ. The kinetics of cytokine production by draining lymph node cells following primary exposure of mice to chemical allergens. Immunology. 1994;83:250 -255. (Pubitemid 24315595)
34. Riffo-Vasquez Y, Spina D. Role of cytokines and chemokines in bronchial hyperresponsiveness and airway inflammation. Pharmacol Ther. 2002;94:185-211. (Pubitemid 34756686)
35. Rosenberg HF, Phipps S, Foster PS. Eosinophil trafficking in allergy and asthma. J Allergy Clin Immunol. 2007;119:1303-1310, quiz 1311-1312. (Pubitemid 46855872)
36. Takatsu K, Nakajima H. IL-5 and eosinophilia. Curr Opin Immunol. 2008;20:288 -294.
37. Gerhold K, Bluemchen K, Franke A, Stock P, Hamelmann E. Expo-sure to endotoxin and allergen in early life and its effect on allergen sensitization in mice. J Allergy Clin Immunol. 2003;112:389 -396. (Pubitemid 36981381)
38. Miller BA, Crum JM, Tovar CA, Ferguson AR, Bresnahan JC, Beattie MS. Developmental stage of oligodendrocytes determines their response to activated microglia in vitro. J Neuroinflammation. 2007;4:28.
39. Sawa Y, Ueki T, Hata M, Iwasawa K, Tsuruga E, et al. LPS-induced IL-6, IL-8, VCAM-1, and ICAM-1 Expression in Human Lymphatic Endothelium. J Histochem Cytochem. 2008;56:97-109. (Pubitemid 351170963)
40. Beck-Schimmer B, Schwendener R, Pasch T, Reyes L, Booy C, Schimmer RC. Alveolar macrophages regulate neutrophil recruitment in endotoxin- induced lung injury. Respir Res. 2005;6:61.
41. Barczyk A, Sozanska E, Farnik M, Stepniak-Ziolkiewicz I, Nizio- Masior J, Pierzchala W. Increased levels of RANTES in induced sputum of chronic asthma but not in seasonal grass pollen-induced rhinitis. Pneumonol Alergol Pol. 2006;74:191-196. (Pubitemid 44504022)
42. Jeffery PK, Wardlaw AJ, Nelson FC, Collins JV, Kay AB. Bronchial biopsies in asthma. An ultrastructural, quantitative study and correlation with hyperreactivity. Am Rev Respir Dis. 1989;140:1745-1753. (Pubitemid 20041063)
43. Venge J, Lampinen M, Hakansson L, Rak S, Venge P. Identification of IL-5 and RANTES as the major eosinophil chemoattractants in the asthmatic lung. J Allergy Clin Immunol. 1996;97:1110 -1115. (Pubitemid 26154209)
44. Wark PA, Simpson J, Hensley MJ, Gibson PG. Airway inflammation in thunderstorm asthma. Clin Exp Allergy. 2002;32:1750 -1756. (Pubitemid 35463861)
45. Wright SM, Hockey PM, Enhorning G, Strong P, Reid KB, et al. Altered airway surfactant phospholipid composition and reduced lung function in asthma. J Appl Physiol. 2000;89:1283-1292.
46. Badorrek P, Larbig M, Dick M, et al. The role of pollen starch granules in bronchial inflammation. Allergy. 2008;63(88S):65.
47. Ma CS, Chew GY, Simpson N, Priyadarshi A, Wong M, et al. Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3. J Exp Med. 2008;205:1551-1557. (Pubitemid 351962018)
48. Boldogh I, Bacsi A, Choudhury BK, Dharajiya N, Alam R, et al. ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation. J Clin Invest. 2005;115: 2169-2179. (Pubitemid 41134158)
49. Rylander R, Fogelmark B, McWilliam A, Currie A. (133)-beta-Dglucan may contribute to pollen sensitivity. Clin Exp Immunol. 1999; 115:383-384. (Pubitemid 29130348)
50. Wang XL, Takai T, Kamijo S, Gunawan H, Ogawa H, Okumura K. NADPH oxidase activity in allergenic pollen grains of different plant species. Biochem Biophys Res Commun. 2009;387:430-434.