Paracrine signalling loops in adult human and mouse pancreatic islets: Netrins modulate beta cell apoptosis signalling via dependence receptors

Diabetologia

Volumn 54, Issue 4, 2011, Pages 828-842

  Yang, Y H C ^a   Szabat, M ^a   Bragagnini, C ^a   Kott, K ^a   Helgason, C D ^c   Hoffman, B G ^b   Johnson, J D ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

Author keywords

Axon guidance factors; Cytokines; Diabetes; Growth factors; Hormones; Netrin

Indexed keywords

CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE; NEOGENIN; NETRIN; NETRIN 1; NETRIN 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; BIOLOGICAL ACTIVITY; CELL FUNCTION; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION PROFILING; GENE LIBRARY; GENE SEQUENCE; HYPERGLYCEMIA; IMMUNOFLUORESCENCE TEST; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN CLEAVAGE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL LINE; COMPUTATIONAL BIOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NERVE GROWTH FACTORS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, CELL SURFACE; RECEPTORS, NERVE GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79953820887     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-2012-5     Document Type: Article

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