A peptidoglycan monomer with the glutamine to serine change and basic peptides bind in silico to TLR-2 (403-455)

Cancer Immunology, Immunotherapy

Volumn 60, Issue 4, 2011, Pages 515-524

  Li, Yufeng ^a   Efferson, Clay L ^a,c   Ramesh, Rajagopal ^a   Peoples, George E ^b   Hwu, Patrick ^a   Ioannides, Constantin G ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b BROOKE ARMY MEDICAL CENTER   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Bind TLR 2; Charged peptides; Molecular simulation; PGN monomers

Indexed keywords

ARGININE; GLUTAMINE; LYSINE; MONOMER; N ACETYLGLUCOSAMINE; PEPTIDOGLYCAN; SERINE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 2[403-455]; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPUTER MODEL; CONTROLLED STUDY; DIMERIZATION; HUMAN; HUMAN CELL; MOLECULAR DOCKING; MOLECULAR MODEL; MONOCYTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; BINDING SITES; COMPUTATIONAL BIOLOGY; GLUTAMINE; HUMANS; MACROPHAGE ACTIVATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDOGLYCAN; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SERINE; TOLL-LIKE RECEPTOR 2;

EID: 79953805448     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-010-0959-1     Document Type: Article

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