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Volumn 37, Issue 5, 2011, Pages 518-525

Permeation studies on freshly excised rat gastric mucosa: Influence of pH

Author keywords

cell viability; Gastric absorption; permeability; pH dependence; Ussing chamber

Indexed keywords

BACITRACIN; CIMETIDINE; FLUORESCEIN SODIUM; PROPRANOLOL;

EID: 79953798446     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2010.527348     Document Type: Article
Times cited : (5)

References (31)
  • 1
    • 0031890348 scopus 로고    scopus 로고
    • Evaluation of oral mucoadhesive microspheres in man on the basis of the pharmacokinetics of furosemide and riboflavin, compounds with limited gastrointestinal absorption sites
    • Akiyama Y, Nagahara N, Nara E, Kitano M, Iwasa S, Yamamoto I, Azuma J, Ogawa Y. (1998). Evaluation of oral mucoadhesive microspheres in man on the basis of the pharmacokinetics of furosemide and riboflavin, compounds with limited gastrointestinal absorption sites. J Pharm Pharmacol 50:159-166. (Pubitemid 28102572)
    • (1998) Journal of Pharmacy and Pharmacology , vol.50 , Issue.2 , pp. 159-166
    • Akiyama, Y.1    Nagahara, N.2    Nara, E.3    Kitano, M.4    Iwasa, S.5    Yamamoto, I.6    Azuma, J.7    Ogawa, Y.8
  • 2
    • 0023525714 scopus 로고
    • Intracellular pH (pH(i)) in gastric surface epithelium is more susceptible to serosal than mucosal acidification
    • Ashley SW, Soybel DI, Moore CD, Cheung LY. (1987). Intracellular pH (pHi) in gastric surface epithelium is more susceptible to serosal than mucosal acidification. Surgery 102:371-379. (Pubitemid 17158339)
    • (1987) Surgery , vol.102 , Issue.2 , pp. 371-379
    • Ashley, S.W.1    Soybel, D.I.2    Moore, C.D.3    Cheung, L.Y.4
  • 7
    • 62649126219 scopus 로고    scopus 로고
    • Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: The role of efflux transport in the oral absorption of BCS class III drugs
    • Dahan A, Amidon GL. (2009). Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs. Mol Pharm 6:19-28.
    • (2009) Mol Pharm , vol.6 , pp. 19-28
    • Dahan, A.1    Amidon, G.L.2
  • 8
    • 0035078138 scopus 로고    scopus 로고
    • Anatomical and physiological parameters affecting gastrointestinal absorption in humans and rats
    • DOI 10.1016/S0278-6915(00)00136-8, PII S0278691500001368
    • DeSesso JM, Jacobson CF. (2001). Anatomical and physiological parameters affecting gastrointestinal absorption in humans and rats. Food Chem Toxicol 39:209-228. (Pubitemid 32244129)
    • (2001) Food and Chemical Toxicology , vol.39 , Issue.3 , pp. 209-228
    • DeSesso, J.M.1    Jacobson, C.F.2
  • 12
    • 0036481691 scopus 로고    scopus 로고
    • Gastrointestinal transit and drug absorption
    • DOI 10.1248/bpb.25.149
    • Kimura T, Higaki K. (2002). Gastrointestinal transit and drug absorption. Biol Pharm Bull 25:149-164. (Pubitemid 39592096)
    • (2002) Biological and Pharmaceutical Bulletin , vol.25 , Issue.2 , pp. 149-164
    • Kimura, T.1    Higaki, K.2
  • 13
    • 2642674446 scopus 로고    scopus 로고
    • Differences in pH-dependent activation rates of substituted benzimidazoles and biological in vitro correlates
    • DOI 10.1159/000028183
    • Kromer W, Krüger U, Huber R, Hartmann M, Steinijans VW. (1998). Differences in pH-dependent activation rates of substituted benzimidazoles and biological in vitro correlates. Pharmacology 56:57-70. (Pubitemid 28039688)
    • (1998) Pharmacology , vol.56 , Issue.2 , pp. 57-70
    • Kromer, W.1    Kruger, U.2    Huber, R.3    Hartmann, M.4    Steinijans, V.W.5
  • 15
    • 0027033869 scopus 로고
    • The "limiting ridge" of the rat stomach
    • Luciano L, Reale E. (1992). The "limiting ridge" of the rat stomach. Arch Histol Cytol 55(Suppl):131-138.
    • (1992) Arch Histol Cytol , vol.55 , Issue.SUPPL. , pp. 131-138
    • Luciano, L.1    Reale, E.2
  • 16
    • 0025786682 scopus 로고
    • Biopharmaceutic evaluation of furosemide as a potential candidate for a modified release peroral dosage form
    • Menon A, Ritschel WA, Sakr A. (1991). Biopharmaceutic evaluation of furosemide as a potential candidate for a modified release peroral dosage form. Methods Find Exp Clin Pharmacol 13:629-636.
    • (1991) Methods Find Exp Clin Pharmacol , vol.13 , pp. 629-636
    • Menon, A.1    Ritschel, W.A.2    Sakr, A.3
  • 17
    • 57749177459 scopus 로고    scopus 로고
    • Movement of heparins across rat gastric mucosa is dependent on molecular weight and pH
    • Moazed B, Hiebert LM. (2009). Movement of heparins across rat gastric mucosa is dependent on molecular weight and pH. Pharm Res 26:189-195.
    • (2009) Pharm Res , vol.26 , pp. 189-195
    • Moazed, B.1    Hiebert, L.M.2
  • 18
    • 0029058534 scopus 로고
    • Gastric pH influences the appearance of double peaks in the plasma concentration-time profiles of cimetidine after oral administration in dogs
    • Mummaneni V, Amidon GL, Dressman JB. (1995). Gastric pH influences the appearance of double peaks in the plasma concentration-time profiles of cimetidine after oral administration in dogs. Pharm Res 12:780-786.
    • (1995) Pharm Res , vol.12 , pp. 780-786
    • Mummaneni, V.1    Amidon, G.L.2    Dressman, J.B.3
  • 20
    • 2542463003 scopus 로고    scopus 로고
    • Reversed-phase liquid chromatography with ultraviolet detection for simultaneous quantitation of indinavir and propranolol from ex-vivo rat intestinal permeability studies
    • DOI 10.1016/j.jchromb.2004.04.009, PII S1570023204003289
    • Panchagnula R, Bansal T, Varma MV, Kaul CL. (2004). Reversed-phase liquid chromatography with ultraviolet detection for simultaneous quantitation of indinavir and propranolol from ex-vivo rat intestinal permeability studies. J Chromatogr B Analyt Technol Biomed Life Sci 806:277-282. (Pubitemid 38686517)
    • (2004) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.806 , Issue.2 , pp. 277-282
    • Panchagnula, R.1    Bansal, T.2    Varma, M.V.S.3    Kaul, C.L.4
  • 21
    • 0038018460 scopus 로고    scopus 로고
    • The stomach as a site for anthocyanins absorption from food
    • DOI 10.1016/S0014-5793(03)00504-0
    • Passamonti S, Vrhovsek U, Vanzo A, Mattivi F. (2003). The stomach as a site for anthocyanins absorption from food. FEBS Lett 544:210-213. (Pubitemid 36628064)
    • (2003) FEBS Letters , vol.544 , Issue.1-3 , pp. 210-213
    • Passamonti, S.1    Vrhovsek, U.2    Vanzo, A.3    Mattivi, F.4
  • 22
    • 0033048388 scopus 로고    scopus 로고
    • Daidzein and genistein but not their glucosides are absorbed from the rat stomach
    • DOI 10.1016/S0014-5793(99)00307-5, PII S0014579399003075
    • Piskula MK, Yamakoshi J, Iwai Y. (1999). Daidzein and genistein but not their glucosides are absorbed from the rat stomach. FEBS Lett 447:287-291. (Pubitemid 29146103)
    • (1999) FEBS Letters , vol.447 , Issue.2-3 , pp. 287-291
    • Piskula, M.K.1    Yamakoshi, J.2    Iwai, Y.3
  • 23
    • 67549108385 scopus 로고    scopus 로고
    • Permeation of four oral drugs through human intestinal mucosa
    • Pretorius E, Bouic PJ. (2009). Permeation of four oral drugs through human intestinal mucosa. AAPS PharmSciTech 10:270-275.
    • (2009) AAPS PharmSciTech , vol.10 , pp. 270-275
    • Pretorius, E.1    Bouic, P.J.2
  • 27
    • 0020666826 scopus 로고
    • Studies of the pH gradient and thickness of frog gastric mucus gel
    • Takeuchi K, Magee D, Critchlow J, Matthews J, Silen W. (1983). Studies of the pH gradient and thickness of frog gastric mucus gel. Gastroenterology 84:331-340. (Pubitemid 13224274)
    • (1983) Gastroenterology , vol.84 , Issue.2 , pp. 331-340
    • Takeuchi, K.1    Magee, D.2    Critchlow, J.3
  • 29
    • 79953787988 scopus 로고    scopus 로고
    • U.S. Pharmacopeia 30
    • U.S. Pharmacopeia, 30. National Formulary 25, Vol. 1, p. 810.
    • National Formulary 25 , vol.1 , pp. 810
  • 30
    • 0042167430 scopus 로고    scopus 로고
    • P-glycoprotein inhibitors and their screening: A perspective from bioavailability enhancement
    • DOI 10.1016/S1043-6618(03)00158-0
    • Varma MV, Ashokraj Y, Dey CS, Panchagnula R. (2003). P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement. Pharmacol Res 48:347-359. (Pubitemid 36945333)
    • (2003) Pharmacological Research , vol.48 , Issue.4 , pp. 347-359
    • Varma, M.V.S.1    Ashokraj, Y.2    Dey, C.S.3    Panchagnula, R.4
  • 31
    • 75149187815 scopus 로고    scopus 로고
    • Improving sublingual delivery of weak base compounds using pH(max) concept: Application to propranolol
    • Wang Y, Zuo Z, Chen X, Tomlinson B, Chow MS. (2010). Improving sublingual delivery of weak base compounds using pH(max) concept: application to propranolol. Eur J Pharm Sci 39: 272-278.
    • (2010) Eur J Pharm Sci , vol.39 , pp. 272-278
    • Wang, Y.1    Zuo, Z.2    Chen, X.3    Tomlinson, B.4    Chow, M.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.