Pharmacokinetics of oral amlodipine orotate in vagotomized dogs

Biopharmaceutics and Drug Disposition

Volumn 27, Issue 3, 2006, Pages 141-145

  Kwak, Hyun H ^a   Kim, Jong O ^a   Chung, Han K ^a   Choi, Seul M ^a   Kim, Jung H ^a   Kwon, Jong W ^a   Yoo, Moohi ^a   Lee, Joo H ^b   Lee, Myung G ^b  

^a Dong A Pharmaceutical Company   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Amlodipine orotate tablet; Dissolution rates; Gastric acid secretion; Gastric motility; Pharmacokinetics; Vagotomized dogs

Indexed keywords

AMLODIPINE; AMLODIPINE OROTATE; TELAZOL; TIROPRAMIDE; UNCLASSIFIED DRUG; ZOLETIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOG; DOSE RESPONSE; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG SOLUBILITY; GASTROINTESTINAL ABSORPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; STOMACH ACID SECRETION; STOMACH MOTILITY; STOMACH PH; VAGOTOMY;

ADMINISTRATION, ORAL; AMLODIPINE; ANIMALS; AREA UNDER CURVE; CALCIUM CHANNEL BLOCKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; GASTROINTESTINAL MOTILITY; HYDROGEN-ION CONCENTRATION; INTESTINAL ABSORPTION; MALE; MASS SPECTROMETRY; METABOLIC CLEARANCE RATE; MODELS, ANIMAL; SOLUBILITY; TABLETS; TIME FACTORS; VAGOTOMY;

EID: 33646364028     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.495     Document Type: Article

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