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Volumn 26, Issue 1, 2009, Pages 189-195

Movement of heparins across rat gastric mucosa is dependent on molecular weight and pH

Author keywords

Absorption; Gastric mucosa; Low molecular weight heparins; Rat; Unfractionated heparin

Indexed keywords

BUFFER; GLUCOSE; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; MANNITOL; REVIPARIN; TINZAPARIN;

EID: 57749177459     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9751-8     Document Type: Article
Times cited : (5)

References (30)
  • 2
    • 0025731009 scopus 로고
    • Evidence from endothelium of gastric absorption of heparin and of dextran sulfates 8000
    • L. B. Jaques L. M. Hiebert S. M. Wice 1991 Evidence from endothelium of gastric absorption of heparin and of dextran sulfates 8000 J. Lab. Clin. Med. 117 122 130
    • (1991) J. Lab. Clin. Med. , vol.117 , pp. 122-130
    • Jaques, L.B.1    Hiebert, L.M.2    Wice, S.M.3
  • 3
    • 3242697941 scopus 로고    scopus 로고
    • Tissue distribution of the low molecular weight heparin, tinzaparin, following administration to rats by the oral route
    • 6
    • L. M. Hiebert S. M. Wice T. Ping 2004 Tissue distribution of the low molecular weight heparin, tinzaparin, following administration to rats by the oral route Biomed. Pharmacother. 58 6 372 380
    • (2004) Biomed. Pharmacother. , vol.58 , pp. 372-380
    • Hiebert, L.M.1    Wice, S.M.2    Ping, T.3
  • 4
    • 2442540022 scopus 로고    scopus 로고
    • Orally administered heparins prevent arterial thrombosis in a rat model
    • C. Pinel S. M. Wice L. M. Hiebert 2004 Orally administered heparins prevent arterial thrombosis in a rat model Thromb. Haemost. 91 919 926
    • (2004) Thromb. Haemost. , vol.91 , pp. 919-926
    • Pinel, C.1    Wice, S.M.2    Hiebert, L.M.3
  • 5
    • 0027264167 scopus 로고
    • The heparin target organ-the endothelium: Studies in a rat model
    • L. M. Hiebert S. M. Wice N. M. McDuffie L. B. Jaques 1993 The heparin target organ-the endothelium: Studies in a rat model Q. J. Med. 86 341 348
    • (1993) Q. J. Med. , vol.86 , pp. 341-348
    • Hiebert, L.M.1    Wice, S.M.2    McDuffie, N.M.3    Jaques, L.B.4
  • 6
    • 0035173491 scopus 로고    scopus 로고
    • Antithrombotic efficacy in a rat model of the low molecular weight heparin, reviparin sodium, administered by the oral route
    • L. M. Hiebert S. M. Wice T. Ping D. Herr V. Laux 2001 Antithrombotic efficacy in a rat model of the low molecular weight heparin, reviparin sodium, administered by the oral route Thromb. Haemost. 85 114 118
    • (2001) Thromb. Haemost. , vol.85 , pp. 114-118
    • Hiebert, L.M.1    Wice, S.M.2    Ping, T.3    Herr, D.4    Laux, V.5
  • 7
    • 0017149366 scopus 로고
    • Effects of acidity, cations and alcoholic fractionation on absorption of heparin from gastrointestinal tract
    • T. K. Sue L. B. Jaques E. Yuen 1976 Effects of acidity, cations and alcoholic fractionation on absorption of heparin from gastrointestinal tract Can. J. Physiol. Pharmacol. 54 613 617
    • (1976) Can. J. Physiol. Pharmacol. , vol.54 , pp. 613-617
    • Sue, T.K.1    Jaques, L.B.2    Yuen, E.3
  • 10
    • 34250711342 scopus 로고    scopus 로고
    • An in vitro study with an Ussing chamber showing that unfractionated heparin crosses rat gastric mucosa
    • B. Moazed L. M. Hiebert 2007 An in vitro study with an Ussing chamber showing that unfractionated heparin crosses rat gastric mucosa JPET 322 299 305
    • (2007) JPET , vol.322 , pp. 299-305
    • Moazed, B.1    Hiebert, L.M.2
  • 11
    • 0035038087 scopus 로고    scopus 로고
    • Development of oral heparin therapy for prophylaxis and treatment of deep venous thrombosis
    • S. R. Money J. W. York 2001 Development of oral heparin therapy for prophylaxis and treatment of deep venous thrombosis Cardiovasc. Surg. 9 211 218
    • (2001) Cardiovasc. Surg. , vol.9 , pp. 211-218
    • Money, S.R.1    York, J.W.2
  • 12
    • 0032745131 scopus 로고    scopus 로고
    • Production and chemical processing of low molecular weight heparins
    • 3
    • R. J. Linhardt N. S. Gunay 1999 Production and chemical processing of low molecular weight heparins Sem. Thromb. Hem. 25 3 5 16
    • (1999) Sem. Thromb. Hem. , vol.25 , pp. 5-16
    • Linhardt, R.J.1    Gunay, N.S.2
  • 13
    • 2542448427 scopus 로고
    • European Pharmacopedia Commission.
    • European Pharmacopedia Commission. Pharmeuropa. 3:161-165 (1991).
    • (1991) Pharmeuropa , vol.3 , pp. 161-165
  • 15
    • 0017680992 scopus 로고
    • Determination of heparin and related sulfated mucopolysaccharides
    • L. B. Jaques 1977 Determination of heparin and related sulfated mucopolysaccharides Methods Biochem. Anal. 24 203 312
    • (1977) Methods Biochem. Anal. , vol.24 , pp. 203-312
    • Jaques, L.B.1
  • 16
    • 34250705671 scopus 로고
    • Gastrointestinal pH in rats as determined by the glass electrode
    • I. M. Eastman E. G. Miller 1935 Gastrointestinal pH in rats as determined by the glass electrode J. Biol. Chem. 110 255 262
    • (1935) J. Biol. Chem. , vol.110 , pp. 255-262
    • Eastman, I.M.1    Miller, E.G.2
  • 17
    • 0024338219 scopus 로고
    • Investigations on plasma activity of low molecular weight heparin after intravenous and oral administrations
    • 2
    • M. Dryjski D. E. Schneider P. Mojaverian B. S. Kuo T. D. Bjornsson 1989 Investigations on plasma activity of low molecular weight heparin after intravenous and oral administrations Br. J. Clin. Pharmacol. 28 2 188 192
    • (1989) Br. J. Clin. Pharmacol. , vol.28 , pp. 188-192
    • Dryjski, M.1    Schneider, D.E.2    Mojaverian, P.3    Kuo, B.S.4    Bjornsson, T.D.5
  • 18
    • 0034816352 scopus 로고    scopus 로고
    • Orally active heparin and low-molecular-weight heparin
    • 5
    • G. F. Pineo R. D. Hull V. J. Marder 2001 Orally active heparin and low-molecular-weight heparin Curr. Opin. Pulm. Med. 7 5 344 348
    • (2001) Curr. Opin. Pulm. Med. , vol.7 , pp. 344-348
    • Pineo, G.F.1    Hull, R.D.2    Marder, V.J.3
  • 19
    • 0001502515 scopus 로고
    • Gastro-intestinal absorption of heparin and synthetic heparinoids
    • E. Windsor G. Cronheim 1961 Gastro-intestinal absorption of heparin and synthetic heparinoids Nature 190 263 264
    • (1961) Nature , vol.190 , pp. 263-264
    • Windsor, E.1    Cronheim, G.2
  • 20
    • 0021985742 scopus 로고
    • Sodium deoxycholate promotes the absorption of heparin administered orally, probably by acting on gastrointestinal mucosa, in rats
    • 3
    • S. Guarini W. Ferrari 1985 Sodium deoxycholate promotes the absorption of heparin administered orally, probably by acting on gastrointestinal mucosa, in rats Experientia 41 3 350 352
    • (1985) Experientia , vol.41 , pp. 350-352
    • Guarini, S.1    Ferrari, W.2
  • 21
    • 0026745537 scopus 로고
    • Structural requirements for duodenal permeability of heparin-diamine complexes
    • 1
    • G. Zoppetti I. Caramazza Y. Murakami T. Ohno 1992 Structural requirements for duodenal permeability of heparin-diamine complexes Biochim. Biophys. Acta. 1156 1 92 98
    • (1992) Biochim. Biophys. Acta. , vol.1156 , pp. 92-98
    • Zoppetti, G.1    Caramazza, I.2    Murakami, Y.3    Ohno, T.4
  • 23
    • 0027968406 scopus 로고
    • Oral treatment with low molecular weight heparin normalizes blood pressure in hypertensive rats
    • 1
    • S. Vasdev C. A. Ford L. Longerich B. Barrett S. Parai N. Campbell 1994 Oral treatment with low molecular weight heparin normalizes blood pressure in hypertensive rats Artery 21 1 1 28
    • (1994) Artery , vol.21 , pp. 1-28
    • Vasdev, S.1    Ford, C.A.2    Longerich, L.3    Barrett, B.4    Parai, S.5    Campbell, N.6
  • 24
    • 0033952724 scopus 로고    scopus 로고
    • Absorption and antithrombotic activity of unfractioned heparin after intraduodenal administration in rats
    • V. Costantini R. Deveglia A. Stabile G.G. Nenci 2000 Absorption and antithrombotic activity of unfractioned heparin after intraduodenal administration in rats Blood Coagul. Fibrinolysis. 11 7 13
    • (2000) Blood Coagul. Fibrinolysis. , vol.11 , pp. 7-13
    • Costantini, V.1    Deveglia, R.2    Stabile, A.3    Nenci, G.G.4
  • 25
  • 27
    • 0002727415 scopus 로고
    • Heparin uptake on endothelium
    • L. M. Hiebert L. B. Jaques 1976 Heparin uptake on endothelium Artery 2 26 37
    • (1976) Artery , vol.2 , pp. 26-37
    • Hiebert, L.M.1    Jaques, L.B.2
  • 28
    • 0024321242 scopus 로고
    • The intracellular uptake and protracted release of exogenous heparins by cultured endothelial cells
    • L. M. Hiebert N. M. McDuffie 1989 The intracellular uptake and protracted release of exogenous heparins by cultured endothelial cells Artery 16 208 222
    • (1989) Artery , vol.16 , pp. 208-222
    • Hiebert, L.M.1    McDuffie, N.M.2
  • 29
    • 0035990857 scopus 로고    scopus 로고
    • Tissue distribution of [14C]sucrose octasulfate following oral administration to rats
    • 6
    • L. M. Hiebert S. M. Wice T. Ping R. E. Hileman T. Polat R. J. Linhardt 2002 Tissue distribution of [14C]sucrose octasulfate following oral administration to rats Pharm. Res. 19 6 838 844
    • (2002) Pharm. Res. , vol.19 , pp. 838-844
    • Hiebert, L.M.1    Wice, S.M.2    Ping, T.3    Hileman, R.E.4    Polat, T.5    Linhardt, R.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.