Novel hydrazine molecules as tools to understand the flexibility of vascular adhesion protein-1 ligand-binding site: Toward more selective inhibitors

Journal of Medicinal Chemistry

Volumn 54, Issue 7, 2011, Pages 2143-2154

  Nurminen, Elisa M ^a   Pihlavisto, Marjo ^b   Lázár, László ^c   Pentikäinen, Ulla ^a   Fülöp, Ferenc ^c   Pentikäinen, Olli T ^a  

^a UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^b Biotie Therapies Corp   (Finland)

^c UNIVERSITY OF SZEGED   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); HYDRAZINE DERIVATIVE; VASCULAR ADHESION PROTEIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; DEPRESSION; DIABETES MELLITUS; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; IN VITRO STUDY; LIGAND BINDING; MOLECULAR DYNAMICS; NONHUMAN; OBESITY; PSORIASIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

AMINE OXIDASE (COPPER-CONTAINING); ANIMALS; BINDING SITES; CELL ADHESION MOLECULES; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; HYDRAZINES; LIGANDS; MOLECULAR DYNAMICS SIMULATION; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; PROTEIN CONFORMATION; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 79953794179     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200059p     Document Type: Article

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