Long-term effects and colectomy rates in ulcerative colitis patients treated with infliximab: A Danish single center experience

Scandinavian Journal of Gastroenterology

Volumn 45, Issue 12, 2010, Pages 1457-1463

  Teisner, Ane Søgaard ^a   Ainsworth, Mark A ^a   Brynskov, Jørn ^a  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Clinical response; Colectomy rates; Inflammatory bowel disease; Infliximab; Long term effect; TNF antibody; Ulcerative colitis

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; INFLIXIMAB; MERCAPTOPURINE; MESALAZINE; METHOTREXATE;

ACUTE DISEASE; ADULT; AGED; ARTICLE; CHRONIC DISEASE; COLON RESECTION; DELAYED HYPERSENSITIVITY; DISEASE SEVERITY; DRUG HYPERSENSITIVITY; DRUG MEGADOSE; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; PUSTULOSIS; RETROSPECTIVE STUDY; SMALL INTESTINE OBSTRUCTION; TREATMENT OUTCOME; TREATMENT RESPONSE; ULCERATIVE COLITIS;

ADOLESCENT; ADULT; AGED; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL; COLECTOMY; COLITIS, ULCERATIVE; DENMARK; FEMALE; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 78649235240     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2010.510572     Document Type: Article

References (20)

1. Jarnerot G, Rolny P, Sandberg-Gertzen H. Intensive intravenous treatment of ulcerative colitis. Gastroenterology 1985;89:1005-13.
2. Travis SP, Farrant JM, Ricketts C, Nolan DJ, Mortensen NM, Kettlewell MG, Jewell DP. Predicting outcome in severe ulcerative colitis. Gut 1996;38:905-10.
3. Truelove SC, Jewell DP. Intensive intravenous regimen for severe attacks of ulcerative colitis. Lancet 1974;1:1067-70.
4. Arts J, D'Haens G, Zeegers M, Van Assche G, Hiele M, D'Hoore A, et al. Long-term outcome of treatment with intravenous cyclosporin in patients with severe ulcerative colitis. Inflamm Bowel Dis 2004;10:73-8.
5. Garcia-Lopez S, Gomollon-Garcia F, Perez-Gisbert J. Cyclosporine in the treatment of severe attack of ulcerative colitis: a systematic review. Gastroenterol Hepatol 2005;28:607-14.
6. Jarnerot G, Hertervig E, Friis-Liby I, Blomquist L, Karlen P, Granno C, et al. Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: a randomized, placebocontrolled study. Gastroenterology 2005;128:1805-11.
7. Rutgeerts P, Sandborn WJ, Feagan BG, Reinisch W, Olson A, Johanns J, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005;353:2462-76.
8. Gustavsson A, Jarnerot G, Hertervig E, Friis-Liby I, Blomquist L, Karlen P, et al. Colectomy after rescue therapy in intravenous-steroid resistant acute ulcerative colitis: a 3-year follow-up study of the swedish-danish infliximab/placebo trial. Abstract, UEGW Vienna 2008.
9. Sandborn WJ, Rutgeerts P, Feagan BG, Reinisch W, Olson A, Johanns J, et al. Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab. Gastroenterology 2009;137:1250-60.
10. Seow CH, Newman A, Irwin SP, Steinhart AH, Silverberg MS, Greenberg GR. Trough serum infliximab: a predictive factor of clinical outcome for infliximab treatment in acute ulcerative Colitis. Gut 2010;59:49-54.
11. Aratari A, Papi C, Clemente V, Moretti A, Luchetti R, Koch M, et al. Colectomy rate in acute severe ulcerative colitis in the infliximab era. Dig Liver Dis 2008;40:821-6.
12. Cury DB, Cury Mde S, Elias GV, Mizsputen SJ. Infliximab to treat severe ulcerative colitis. World J Gastroenterol 2009;15:1771-3.
13. Manosa M, Lopez SR, Garcia-Planella E, Bastida G, Hinojosa J, Gonzalez-Lama Y, et al. Infliximab rescue therapy after cyclosporin failure in steroid-refractory ulcerative colitis. Digestion 2009;80:30-5.
14. Willert RP, Lawrance IC. Use of infliximab in the prevention and delay of colectomy in severe steroid dependant and refractory ulcerative colitis. World J Gastroenterol 2008;14:2544-9.
15. Gonzalez-Lama Y, Fernandez-Blanco I, Lopez-SanRoman A, Taxonera C, Casis B, Tabernero S, et al. Open-label infliximab therapy in ulcerative colitis: a multicenter survey of results and predictors of response. Hepatogastroenterology 2008;55:1609-14.
16. Kohn A, Daperno M, Armuzzi A, Cappello M, Biancone L, Orlando A, et al. Infliximab in severe ulcerative colitis: short-term results of different infusion regimens and longterm follow-up. Aliment Pharmacol Ther 2007;26:747-56.
17. Russo EA, Harris AW, Campbell S, Lindsay J, Hart A, Arebi N, et al. Experience of maintenance infliximab therapy for refractory ulcerative colitis from six centres in England. Aliment Pharmacol Ther 2009;29:308-14.
18. Bressler B, Law JK, Nahdi Al, Sheraisher N, Atkinson K, Byrne MF, et al. The use of infliximab for treatment of hospitalized patients with acute severe ulcerative coitis. Can J Gastroenterol 2008;22:937-40.
19. Satsangi J, Silverberg MS, Vermeire S, Colombel JF. The montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut 2006;55:749-53.
20. Ferrante M. Long-term outcome after infliximab for refractory ulcerative colitis. J Chron's Colitis 2008;2:219-23.