The role of K-ras gene mutation in TRAIL-induced apoptosis in pancreatic and lung cancer cell lines

Cancer Chemotherapy and Pharmacology

Volumn 67, Issue 2, 2011, Pages 481-487

  Sahu, Ravi P ^a   Batra, Sanjay ^a   Kandala, Prabodh K ^a   Brown, Thomas L ^b   Srivastava, Sanjay K ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b WRIGHT STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Chemotherapeutic resistance; K ras; Lung cancer; Pancreatic cancer; TRAIL resistance

Indexed keywords

CASPASE; CASPASE 3; CASPASE 8; K RAS PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BID; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; BID PROTEIN, HUMAN; CALCIMYCIN; PARP1 PROTEIN, HUMAN; RECOMBINANT PROTEIN; TNFSF10 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER CELL; CELL DEATH; CELL SURVIVAL; CODON; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; GENE MUTATION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HUMAN CELL; LUNG CANCER; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SIGNAL TRANSDUCTION; AMINO ACID SUBSTITUTION; DRUG EFFECT; DRUG RESISTANCE; GENETICS; LUNG TUMOR; METABOLISM; ONCOGENE RAS; PANCREAS TUMOR; PHYSIOLOGY; POINT MUTATION; TUMOR CELL LINE;

AMINO ACID SUBSTITUTION; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CALCIMYCIN; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; GENES, RAS; HUMANS; LUNG NEOPLASMS; PANCREATIC NEOPLASMS; POINT MUTATION; POLY(ADP-RIBOSE) POLYMERASES; RECOMBINANT PROTEINS; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 79953769380     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-010-1463-1     Document Type: Article

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