Drug resistance mutations in drug-naive HIV type 1 subtype C-infected individuals from rural Malawi

AIDS Research and Human Retroviruses

Volumn 27, Issue 4, 2011, Pages 439-444

  Bansode, Vijay ^a   Drebert, Zuzanna J ^a   Travers, Simon A A ^a,b   Banda, Emmanuel ^c   Molesworth, Anna ^c,d   Crampin, Amelia ^c,d   Ngwira, Bagrey ^c,d   French, Neil ^c,d   Glynn, Judith R ^c   McCormack, Grace P ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b UNIVERSITY OF THE WESTERN CAPE   (South Africa)

^c KARONGA PREVENTION STUDY   (Malawi)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ARTICLE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; MALAWI; MALE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; UNINDEXED SEQUENCE; VIRUS MUTATION;

ANTI-HIV AGENTS; DRUG RESISTANCE, VIRAL; HIV INFECTIONS; HIV PROTEASE; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; MALAWI; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHYLOGENY; RURAL POPULATION; SEQUENCE ANALYSIS, DNA;

EID: 79953747436     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2010.0203     Document Type: Article

References (15)

1. Ministry of Health: Antiretroviral Treatment Programme in MALAWI. Annual report.
2. Hemelaar J, Gouws E, Ghys PD, and Osmanov S: Global and regional distribution of HIV-1 genetic subtypes and recombinants in 2004. AIDS 2006;20:W13-23.
3. Petch LA, Hoffman IF, Jere CS, et al.: Genotypic analysis of the protease and reverse transcriptase of HIV type 1 subtype C isolates from antiretroviral drug-naive adults in Malawi. AIDS Res Hum Retroviruses 2005;21:799-805. (Pubitemid 41434185)
4. Kassu A, Fujino M, Matsuda M, Nishizawa M, Ota F, and Sugiura W: Molecular epidemiology of HIV type 1 in treatment-naive patients in north Ethiopia. AIDS Res Hum Retroviruses 2007;23:564-568. (Pubitemid 46700891)
5. Bessong PO, Mphahlele J, Choge IA, et al.: Resistance mutational analysis of HIV type 1 subtype C among rural South African drug-naive patients prior to large-scale availability of antiretrovirals. AIDS Res Hum Retroviruses 2006;22: 1306-1312. (Pubitemid 46095250)
6. Handema R, Terunuma H, Kasolo F, et al.: Prevalence of drug-resistance-associated mutations in antiretroviral drug-naive Zambians infected with subtype C HIV-1. AIDS Res Hum Retroviruses 2003;19:151-160. (Pubitemid 36308053)
7. McCormack G, Glynn JR, Crampin AC, et al.: Early evolution of the human immunodeficiency virus type 1 subtype C epidemic in rural Malawi. J Virol 2002;76:12890-12899. (Pubitemid 35386972)
8. Stamatakis A: RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics 2006;22:2688-2690.
9. Rhee SY, Gonzales MJ, Kantor R, Betts BJ, Ravela J, and Shafer RW: Human immunodeficiency virus reverse transcriptase and protease sequence database. Nucleic Acids Res 2003;31:298-303. (Pubitemid 36150389)
10. Rhee SY, Kantor R, Katzenstein DA, et al.: HIV-1 pol mutation frequency by subtype and treatment experience: Extension of the HIVseq program to seven non-B subtypes. AIDS 2006;20:643-651. (Pubitemid 43884290)
11. Hosseinipour MC, van Oosterhout JJ, Weigel R, et al.: The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. AIDS 2009;23:1127-1134.
12. Kieffer TL, Kwon P, Nettles RE, Han Y, Ray SC, and Siliciano RF: G → A hypermutation in protease and reverse transcriptase regions of human immunodeficiency virus type 1 residing in resting CD4+ T cells in vivo. J Virol 2005;79:1975-1980. (Pubitemid 40459148)
13. Goff SP: Death by deamination: A novel host restriction system for HIV-1. Cell 2003;114:281-283.
14. Vidal N, Niyongabo T, Nduwimana J, et al.: HIV type 1 diversity and antiretroviral drug resistance mutations in Burundi. AIDS Res Hum Retroviruses 2007;23:175-180. (Pubitemid 46214187)
15. Somi GR, Kibuka T, Diallo K, et al.: Surveillance of transmitted HIV drug resistance among women attending antenatal clinics in Dar es Salaam, Tanzania. Antivir Ther 2008;13(Suppl 2):77-82. (Pubitemid 352019092)