Gene transcriptional networks integrate microenvironmental signals in human breast cancer

Integrative Biology

Volumn 3, Issue 4, 2011, Pages 368-374

  Xu, Ren ^a,b   Mao, Jian Hua ^c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; FIBROBLAST GROWTH FACTOR; INTERCELLULAR ADHESION MOLECULE 1; MATRIX METALLOPROTEINASE; TRANSFORMING GROWTH FACTOR BETA; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN;

BREAST CANCER; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; EXTRACELLULAR MATRIX; GENETIC TRANSCRIPTION; HUMAN; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; CADHERINS; CYTOKINES; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; INTEGRINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MAMMARY GLANDS, HUMAN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RECEPTORS, CYTOKINE; TRANSFORMING GROWTH FACTOR BETA; TUMOR MICROENVIRONMENT;

EID: 79953743367     PISSN: 17579694     EISSN: 17579708     Source Type: Journal    
DOI: 10.1039/c0ib00087f     Document Type: Review

References (57)

1. M. J. Bissell and D. Radisky, Putting tumours in context, Nat. Rev. Cancer, 2001, 1, 46-54. (Pubitemid 33741880)
2. M. A. LaBarge, C. M. Nelson, R. Villadsen, A. Fridriksdottir, J. R. Ruth, A. Fridriksdottir, J. R. Ruth, M. R. Stampfer, O. W. Petersen and M. J. Bissell, Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments, Integr. Biol., 2009, 1, 70-79.
3. R. Xu, A. Boudreau and M. J. Bissell, Tissue architecture and function: dynamic reciprocity via extra- and intra-cellular matrices, Cancer Metastasis Rev., 2009, 28, 167-176.
4. W. Guo, Y. Pylayeva, A. Pepe, T. Yoshioka and W. J. Muller, et al. Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis, Cell, 2006, 126, 489-502.
5. N. Akhtar and C. H. Streuli, Rac1 links integrin-mediated adhesion to the control of lactational differentiation in mammary epithelia, J. Cell Biol., 2006, 173, 781-793.
6. F. Wang, V. M. Weaver, O. W. Petersen, C. A. Larabell and S. Dedhar, et al. Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology, Proc. Natl. Acad. Sci. U. S. A., 1998, 95, 14821-14826.
7. R. Xu, C. M. Nelson, J. L. Muschler, M. Veiseh and B. K. Vonderhaar, et al. Sustained activation of STAT5 is essential for chromatin remodeling and maintenance of mammary-specific function, J. Cell Biol., 2009, 184, 57-66.
8. C. H. Streuli, G. M. Edwards, M. Delcommenne, C. B. Whitelaw and T. G. Burdon, et al. Stat5 as a target for regulation by extracellular matrix, J. Biol. Chem., 1995, 270, 21639-21644.
9. V. Goffin, N. Binart, P. Touraine and P. A. Kelly, Prolactin: the new biology of an old hormone, Annu. Rev. Physiol., 2002, 64, 47-67.
10. F. Gouilleux, H. Wakao, M. Mundt and B. Groner, Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription, EMBO J., 1994, 13, 4361-4369.
11. C. J. Watson and T. G. Burdon, Prolactin signal transduction mechanisms in the mammary gland: the role of the Jak/Stat pathway, Rev. Reprod., 1996, 1, 1-5.
12. R. Xu, V. A. Spencer and M. J. Bissell, Extracellular matrix-regulated gene expression requires cooperation of SWI/SNF and transcription factors, J. Biol. Chem., 2007, 282, 14992-14999. (Pubitemid 47093328)
13. C. D. Roskelley, P. Y. Desprez and M. J. Bissell, Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction, Proc. Natl. Acad. Sci. U. S. A., 1994, 91, 12378-12382.
14. R. O. Hynes, Integrins: bidirectional, allosteric signaling machines, Cell, 2002, 110, 673-687.
15. M. J. Naylor, N. Li, J. Cheung, E. T. Lowe and E. Lambert, et al. Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation, J. Cell Biol., 2005, 171, 717-728. (Pubitemid 41668730)
16. G. P. Gui, C. A. Wells, P. D. Browne, P. Yeomans and S. Jordan, et al. Integrin expression in primary breast cancer and its relation to axillary nodal status, Surgery, 1995, 117, 102-108.
17. D. J. Slamon, G. M. Clark, S. G. Wong, W. J. Levin and A. Ullrich, et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene, Science, 1987, 235, 177-182.
18. V. M. Weaver, O. W. Petersen, F. Wang, C. A. Larabell and P. Briand, et al. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrinblocking antibodies, J. Cell Biol., 1997, 137, 231-245.
19. C. Margadant, E. Frijns, K. Wilhelmsen and A. Sonnenberg, Regulation of hemidesmosome disassembly by growth factor receptors, Curr. Opin. Cell Biol., 2008, 20, 589-596.
20. K. Wilhelmsen, S. H. Litjens, I. Kuikman, C. Margadant and J. van Rheenen, et al. Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption, Mol. Biol. Cell, 2007, 18, 3512-3522. (Pubitemid 47378689)
21. K. Ieguchi, M. Fujita, Z. Ma, P. Davari and Y. Taniguchi, et al. Direct binding of the EGF-like domain of neuregulin-1 to integrins ({alpha}v{beta}3 and {alpha}6{beta}4) is involved in neuregulin-1/ ErbB signaling, J. Biol. Chem., 2010, 285, 31388-31398.
22. I. Vlodavsky, H. Q. Miao, B. Medalion, P. Danagher and D. Ron, Involvement of heparan sulfate and related molecules in sequestration and growth promoting activity of fibroblast growth factor, Cancer Metastasis Rev., 1996, 15, 177-186. (Pubitemid 26236115)
23. S. Rahman, Y. Patel, J. Murray, K. V. Patel and R. Sumathipala, et al. Novel hepatocyte growth factor (HGF) binding domains on fibronectin and vitronectin coordinate a distinct and amplified Met-integrin induced signalling pathway in endothelial cells, BMC Cell Biol., 2005, 6, 8.
24. V. Brinkmann, H. Foroutan, M. Sachs, K. M. Weidner and W. Birchmeier, Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells, J. Cell Biol., 1995, 131, 1573-1586.
25. T. L. Woodward, A. S. Mienaltowski, R. R. Modi, J. M. Bennett and S. Z. Haslam, Fibronectin and the alpha(5)beta(1) integrin are under developmental and ovarian steroid regulation in the normal mouse mammary gland, Endocrinology, 2001, 142, 3214-3222.
26. X. Wang, R. E. Harris, L. J. Bayston and H. L. Ashe, Type IV collagens regulate BMP signalling in Drosophila, Nature, 2008, 455, 72-77.
27. V. Delmas, P. Pla, H. Feracci, J. P. Thiery and R. Kemler, et al. Expression of the cytoplasmic domain of E-cadherin induces precocious mammary epithelial alveolar formation and affects cell polarity and cell-matrix integrity, Dev. Biol., 1999, 216, 491-506.
28. O. Boussadia, S. Kutsch, A. Hierholzer, V. Delmas and R. Kemler, E-cadherin is a survival factor for the lactating mouse mammary gland, Mech. Dev., 2002, 115, 53-62. (Pubitemid 34615667)
29. N. Borghi, M. Lowndes, V. Maruthamuthu, M. L. Gardel and W. J. Nelson, Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions, Proc. Natl. Acad. Sci. U. S. A., 2010, 107, 13324-13329.
30. M. Perrais, X. Chen, M. Perez-Moreno and B. M. Gumbiner, E-cadherin homophilic ligation inhibits cell growth and epidermal growth factor receptor signaling independently of other cell interactions, Mol. Biol. Cell, 2007, 18, 2013-2025.
31. X. Qian, T. Karpova, A. M. Sheppard, J. McNally and D. R. Lowy, E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases, EMBO J., 2004, 23, 1739-1748.
32. K. R. Legate, E. Montanez, O. Kudlacek and R. Fassler, ILK, PINCH and parvin: the tIPP of integrin signalling, Nat. Rev. Mol. Cell Biol., 2006, 7, 20-31.
33. T. R. McPhee, P. C. McDonald, A. Oloumi and S. Dedhar, Integrin-linked kinase regulates E-cadherin expression through PARP-1, Dev. Dyn., 2008, 237, 2737-2747.
34. M. L. Ackland, D. F. Newgreen, M. Fridman, M. C. Waltham and A. Arvanitis, et al. Epidermal growth factor-induced epitheliomesenchymal transition in human breast carcinoma cells, Lab. Invest., 2003, 83, 435-448.
35. H. S. Moon, E. A. Choi, H. Y. Park, J. Y. Choi and H. W. Chung, et al. Expression and tyrosine phosphorylation of E-cadherin, beta- and gamma-catenin, and epidermal growth factor receptor in cervical cancer cells, Gynecol. Oncol., 2001, 81, 355-359.
36. D. Quigley and A. Balmain, Systems genetics analysis of cancer susceptibility: from mouse models to humans, Nat. Rev. Genet., 2009, 10, 651-657.
37. D. A. Quigley, M. D. To, J. Perez-Losada, F. G. Pelorosso and J. H. Mao, et al. Genetic architecture of mouse skin inflammation and tumour susceptibility, Nature, 2009, 458, 505-508.
38. J. C. Bonner, Regulation of PDGF and its receptors in fibrotic diseases, Cytokine Growth Factor Rev., 2004, 15, 255-273.
39. E. Borkham-Kamphorst, D. Stoll, A. M. Gressner and R. Weiskirchen, Antisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesis, Biochem. Biophys. Res. Commun., 2004, 321, 413-423. (Pubitemid 39055762)
40. M. Yamauchi and M. Shiiba, Lysine hydroxylation and cross-linking of collagen, Methods Mol. Biol., 2008, 446, 95-108.
41. K. R. Levental, H. Yu, L. Kass, J. N. Lakins and M. Egeblad, et al. Matrix crosslinking forces tumor progression by enhancing integrin signaling, Cell, 2009, 139, 891-906.
42. D. Padua and J. Massague, Roles of TGFbeta in metastasis, Cell Res., 2009, 19, 89-102.
43. M. H. Barcellos-Hoff, Latency and activation in the control of TGF-beta, J. Mammary Gland Biol. Neoplasia, 1996, 1, 353-363.
44. J. P. Annes, J. S. Munger and D. B. Rifkin, Making sense of latent TGFbeta activation, J. Cell Sci., 2003, 116, 217-224.
45. J. S. Munger, J. G. Harpel, F. G. Giancotti and D. B. Rifkin, Interactions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1, Mol. Biol. Cell, 1998, 9, 2627-2638.
46. S. E. Crawford, V. Stellmach, J. E. Murphy-Ullrich, S. M. Ribeiro and J. Lawler, et al. Thrombospondin-1 is a major activator of TGF-beta1 in vivo, Cell, 1998, 93, 1159-1170. (Pubitemid 28307421)
47. Q. Yu and I. Stamenkovic, Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis, Genes Dev., 2000, 14, 163-176. (Pubitemid 30070982)
48. A. A. Maghazachi, A. Al-Aoukaty and T. J. Schall, CC chemokines induce the generation of killer cells from CD56+ cells, Eur. J. Immunol., 1996, 26, 315-319. (Pubitemid 26060235)
49. A. E. Karnoub, A. B. Dash, A. P. Vo, A. Sullivan and M.W. Brooks, et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis, Nature, 2007, 449, 557-563. (Pubitemid 47525152)
50. M. J. Robertson, Role of chemokines in the biology of natural killer cells, J. Leukocyte Biol., 2002, 71, 173-183.
51. T. Zhang, C. J. Guo, S. D. Douglas, D. S. Metzger and C. P. O'Brien, et al. Alcohol suppresses IL-2-induced CC chemokine production by natural killer cells, Alcohol.: Clin. Exp. Res., 2005, 29, 1559-1567.
52. M. Inngjerdingen, B. Damaj and A. A. Maghazachi, Expression and regulation of chemokine receptors in human natural killer cells, Blood, 2001, 97, 367-375.
53. M. Nieto, F. Navarro, J. J. Perez-Villar, M. A. del Pozo and R. Gonzalez-Amaro, et al. Roles of chemokines and receptor polarization in NK-target cell interactions, J. Immunol., 1998, 161, 3330-3339.
54. T. M. Carlos and J. M. Harlan, Leukocyte-endothelial adhesion molecules, Blood, 1994, 84, 2068-2101.
55. O. Barreiro, M. Yanez-Mo, J. M. Serrador, M. C. Montoya and M. Vicente-Manzanares, et al. Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes, J. Cell Biol., 2002, 157, 1233-1245. (Pubitemid 34847793)
56. R. Li, P. Nortamo, C. Kantor, P. Kovanen and T. Timonen, et al. A leukocyte integrin binding peptide from intercellular adhesion molecule-2 stimulates T cell adhesion and natural killer cell activity, J. Biol. Chem., 1993, 268, 21474-21477.
57. I. Melero, I. Gabari, A. L. Corbi, M. Relloso and G. Mazzolini, et al. An anti-ICAM-2 (CD102) monoclonal antibody induces immune-mediated regressions of transplanted ICAM-2-negative colon carcinomas, Cancer Res., 2002, 62, 3167-3174. (Pubitemid 34602410)