메뉴 건너뛰기




Volumn 3, Issue 1, 2011, Pages 478-493

From prostate to bone: Key players in prostate cancer bone metastasis

Author keywords

Bone; Chemokines; Metastasis; Prostate

Indexed keywords

BETA 2 MICROGLOBULIN; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR5; CHEMOKINE RECEPTOR CXCR6; CHEMOKINE RECEPTOR CXCR7; CXCL16 CHEMOKINE; ENDOTHELIN 1; FIBROBLAST GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF DIFFERENTIATION 1; INTERLEUKIN 6; LEPTIN; MAMMALIAN TARGET OF RAPAMYCIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPONTIN; PARATHYROID HORMONE RELATED PROTEIN; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; SOMATOMEDIN; SOMATOMEDIN C; STROMAL CELL DERIVED FACTOR 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 79953727024     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers3010478     Document Type: Review
Times cited : (35)

References (69)
  • 1
    • 42949171158 scopus 로고    scopus 로고
    • Garcia, M., Jemal, A., Ward, E.M., Center, M.M., Hao, Y., Siegel, R.L., Thun, M.J., Eds., American Cancer Society: Atlanta, GA, USA
    • Garcia, M., Jemal, A., Ward, E.M., Center, M.M., Hao, Y., Siegel, R.L., Thun, M.J., Eds. Global Cancer Facts & Figures 2007; American Cancer Society: Atlanta, GA, USA, 2007.
    • (2007) Global Cancer Facts & Figures 2007
  • 2
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D.; Weinberg, R.A. The hallmarks of cancer. Cell 2000, 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 6
    • 0035010803 scopus 로고    scopus 로고
    • Metastatic bone disease: Clinical features, pathophysiology and treatment strategies
    • Coleman, R.E. Metastatic bone disease: Clinical features, pathophysiology and treatment strategies. Cancer Treat. Rev. 2001, 27, 165-176.
    • (2001) Cancer Treat. Rev. , vol.27 , pp. 165-176
    • Coleman, R.E.1
  • 8
    • 67649791971 scopus 로고    scopus 로고
    • Denosumab treatment of prostate cancer with bone metastases and increased urine n-telopeptide levels after therapy with intravenous bisphosphonates: Results of a randomized phase ii trial
    • discussion 515-506
    • Fizazi, K.; Bosserman, L.; Gao, G.; Skacel, T.; Markus, R. Denosumab treatment of prostate cancer with bone metastases and increased urine n-telopeptide levels after therapy with intravenous bisphosphonates: Results of a randomized phase ii trial. J. Urol. 2009, 182, 509-515; discussion 515-506.
    • (2009) J. Urol. , vol.182 , pp. 509-515
    • Fizazi, K.1    Bosserman, L.2    Gao, G.3    Skacel, T.4    Markus, R.5
  • 9
    • 77956634017 scopus 로고    scopus 로고
    • Final safety and efficacy analysis of the specific endothelin a receptor antagonist zibotentan (zd4054) in patients with metastatic castration-resistant prostate cancer and bone metastases who were pain-free or mildly symptomatic for pain: A double-blind, placebo-controlled, randomized phase ii trial
    • James, N.D.; Caty, A.; Payne, H.; Borre, M.; Zonnenberg, B.A.; Beuzeboc, P.; McIntosh, S.; Morris, T.; Phung, D.; Dawson, N.A. Final safety and efficacy analysis of the specific endothelin a receptor antagonist zibotentan (zd4054) in patients with metastatic castration-resistant prostate cancer and bone metastases who were pain-free or mildly symptomatic for pain: A double-blind, placebo-controlled, randomized phase ii trial. BJU Int. 2010, 106, 966-973.
    • (2010) BJU Int. , vol.106 , pp. 966-973
    • James, N.D.1    Caty, A.2    Payne, H.3    Borre, M.4    Zonnenberg, B.A.5    Beuzeboc, P.6    McIntosh, S.7    Morris, T.8    Phung, D.9    Dawson, N.A.10
  • 10
    • 55549112219 scopus 로고    scopus 로고
    • Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer
    • Nelson, J.B.; Love, W.; Chin, J.L.; Saad, F.; Schulman, C.C.; Sleep, D.J.; Qian, J.; Steinberg, J.; Carducci, M. Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer. Cancer 2008, 113, 2478-2487.
    • (2008) Cancer , vol.113 , pp. 2478-2487
    • Nelson, J.B.1    Love, W.2    Chin, J.L.3    Saad, F.4    Schulman, C.C.5    Sleep, D.J.6    Qian, J.7    Steinberg, J.8    Carducci, M.9
  • 11
    • 0012420347 scopus 로고    scopus 로고
    • Seer*stat database: Mortality-all cod, aggregated with state, total U.S. (1969-2007). In National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released June 2010, based on the November 2009 submission. Underlying mortality data provided by NCHS (http://www.cdc.gov/nchs)
    • Surveillance, epidemiology, and end results (seer) program (http://www.Seer.Cancer.Gov). Seer*stat database: Mortality-all cod, aggregated with state, total U.S. (1969-2007). In National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released June 2010, based on the November 2009 submission. Underlying mortality data provided by NCHS (http://www.cdc.gov/nchs).
    • Surveillance, epidemiology, and end results (seer) program
  • 12
    • 38549085667 scopus 로고    scopus 로고
    • The bone microenvironment in metastasis; what is special about bone?
    • Bussard, K.M.; Gay, C.V.; Mastro, A.M. The bone microenvironment in metastasis; what is special about bone? Cancer Metastasis Rev. 2008, 27, 41-55.
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 41-55
    • Bussard, K.M.1    Gay, C.V.2    Mastro, A.M.3
  • 13
    • 0642337591 scopus 로고    scopus 로고
    • The systemic progression of human cancer: A focus on the individual disseminated cancer cell--the unit of selection
    • Klein, C.A. The systemic progression of human cancer: A focus on the individual disseminated cancer cell--the unit of selection. Adv. Cancer Res. 2003, 89, 35-67.
    • (2003) Adv. Cancer Res. , vol.89 , pp. 35-67
    • Klein, C.A.1
  • 14
    • 0035906831 scopus 로고    scopus 로고
    • Interactions of human prostatic epithelial cells with bone marrow endothelium: Binding and invasion
    • Scott, L.J.; Clarke, N.W.; George, N.J.; Shanks, J.H.; Testa, N.G.; Lang, S.H. Interactions of human prostatic epithelial cells with bone marrow endothelium: Binding and invasion. Br. J. Cancer 2001, 84, 1417-1423.
    • (2001) Br. J. Cancer , vol.84 , pp. 1417-1423
    • Scott, L.J.1    Clarke, N.W.2    George, N.J.3    Shanks, J.H.4    Testa, N.G.5    Lang, S.H.6
  • 15
    • 0030049852 scopus 로고    scopus 로고
    • Adhesion receptors on bone marrow stromal cells: In vivo expression of vascular cell adhesion molecule-1 by reticular cells and sinusoidal endothelium in normal and gamma-irradiated mice
    • Jacobsen, K.; Kravitz, J.; Kincade, P.W.; Osmond, D.G. Adhesion receptors on bone marrow stromal cells: In vivo expression of vascular cell adhesion molecule-1 by reticular cells and sinusoidal endothelium in normal and gamma-irradiated mice. Blood 1996, 87, 73-82.
    • (1996) Blood , vol.87 , pp. 73-82
    • Jacobsen, K.1    Kravitz, J.2    Kincade, P.W.3    Osmond, D.G.4
  • 17
  • 19
    • 33748080768 scopus 로고    scopus 로고
    • New insights into the role of t cells in the vicious cycle of bone metastases
    • Fournier, P.G.; Chirgwin, J.M.; Guise, T.A. New insights into the role of t cells in the vicious cycle of bone metastases. Curr. Opin. Rheumatol. 2006, 18, 396-404.
    • (2006) Curr. Opin. Rheumatol. , vol.18 , pp. 396-404
    • Fournier, P.G.1    Chirgwin, J.M.2    Guise, T.A.3
  • 20
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • Mundy, G.R. Metastasis to bone: Causes, consequences and therapeutic opportunities. Nat. Rev. Cancer 2002, 2, 584-593.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 584-593
    • Mundy, G.R.1
  • 21
    • 0033153362 scopus 로고    scopus 로고
    • Osteomimetic properties of prostate cancer cells: A hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment
    • Koeneman, K.S.; Yeung, F.; Chung, L.W. Osteomimetic properties of prostate cancer cells: A hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment. Prostate 1999, 39, 246-261.
    • (1999) Prostate , vol.39 , pp. 246-261
    • Koeneman, K.S.1    Yeung, F.2    Chung, L.W.3
  • 24
    • 71849089013 scopus 로고    scopus 로고
    • Independent and cooperative roles of tumor necrosis factor-alpha, nuclear factor-kappab, and bone morphogenetic protein-2 in regulation of metastasis and osteomimicry of prostate cancer cells and differentiation and mineralization of mc3t3-e1 osteoblast-like cells
    • Graham, T.R.; Agrawal, K.C.; Abdel-Mageed, A.B. Independent and cooperative roles of tumor necrosis factor-alpha, nuclear factor-kappab, and bone morphogenetic protein-2 in regulation of metastasis and osteomimicry of prostate cancer cells and differentiation and mineralization of mc3t3-e1 osteoblast-like cells. Cancer Sci. 2010, 101, 103-111.
    • (2010) Cancer Sci. , vol.101 , pp. 103-111
    • Graham, T.R.1    Agrawal, K.C.2    Abdel-Mageed, A.B.3
  • 25
    • 0033985022 scopus 로고    scopus 로고
    • Calcium signals in prostate cancer cells: Specific activation by bone-matrix proteins
    • Lecrone, V.; Li, W.; Devoll, R.E.; Logothetis, C.; Farach-Carson, M.C. Calcium signals in prostate cancer cells: Specific activation by bone-matrix proteins. Cell Calcium 2000, 27, 35-42.
    • (2000) Cell Calcium , vol.27 , pp. 35-42
    • Lecrone, V.1    Li, W.2    Devoll, R.E.3    Logothetis, C.4    Farach-Carson, M.C.5
  • 27
    • 47749109823 scopus 로고    scopus 로고
    • The role of cxc chemokines and their receptors in cancer
    • Vandercappellen, J.; Van Damme, J.; Struyf, S. The role of cxc chemokines and their receptors in cancer. Cancer Lett. 2008, 267, 226-244.
    • (2008) Cancer Lett. , vol.267 , pp. 226-244
    • Vandercappellen, J.1    Van Damme, J.2    Struyf, S.3
  • 29
    • 33750073849 scopus 로고    scopus 로고
    • Rankl-induced ccl22/macrophage-derived chemokine produced from osteoclasts potentially promotes the bone metastasis of lung cancer expressing its receptor ccr4
    • Nakamura, E.S.; Koizumi, K.; Kobayashi, M.; Saitoh, Y.; Arita, Y.; Nakayama, T.; Sakurai, H.; Yoshie, O.; Saiki, I. Rankl-induced ccl22/macrophage-derived chemokine produced from osteoclasts potentially promotes the bone metastasis of lung cancer expressing its receptor ccr4. Clin. Exp. Metastasis 2006, 23, 9-18.
    • (2006) Clin. Exp. Metastasis , vol.23 , pp. 9-18
    • Nakamura, E.S.1    Koizumi, K.2    Kobayashi, M.3    Saitoh, Y.4    Arita, Y.5    Nakayama, T.6    Sakurai, H.7    Yoshie, O.8    Saiki, I.9
  • 30
    • 2942523585 scopus 로고    scopus 로고
    • Cellular niches controlling b lymphocyte behavior within bone marrow during development
    • Tokoyoda, K.; Egawa, T.; Sugiyama, T.; Choi, B.I.; Nagasawa, T. Cellular niches controlling b lymphocyte behavior within bone marrow during development. Immunity 2004, 20, 707-718.
    • (2004) Immunity , vol.20 , pp. 707-718
    • Tokoyoda, K.1    Egawa, T.2    Sugiyama, T.3    Choi, B.I.4    Nagasawa, T.5
  • 31
    • 0030002637 scopus 로고    scopus 로고
    • Hiv-1 entry cofactor: Functional cdna cloning of a seven-transmembrane, g protein-coupled receptor
    • Feng, Y.; Broder, C.C.; Kennedy, P.E.; Berger, E.A. Hiv-1 entry cofactor: Functional cdna cloning of a seven-transmembrane, g protein-coupled receptor. Science 1996, 272, 872-877.
    • (1996) Science , vol.272 , pp. 872-877
    • Feng, Y.1    Broder, C.C.2    Kennedy, P.E.3    Berger, E.A.4
  • 33
    • 38949185673 scopus 로고    scopus 로고
    • Chemokine receptor cxcr4 expression and prognosis in patients with metastatic prostate cancer
    • Akashi, T.; Koizumi, K.; Tsuneyama, K.; Saiki, I.; Takano, Y.; Fuse, H. Chemokine receptor cxcr4 expression and prognosis in patients with metastatic prostate cancer. Cancer Sci. 2008, 99, 539-542.
    • (2008) Cancer Sci. , vol.99 , pp. 539-542
    • Akashi, T.1    Koizumi, K.2    Tsuneyama, K.3    Saiki, I.4    Takano, Y.5    Fuse, H.6
  • 34
    • 78751493647 scopus 로고    scopus 로고
    • Loss of pten permits cxcr4-mediated tumorigenesis through erk1/2 in prostate cancer cells
    • doi:10.1158/1541-7786.MCR-10-0235
    • Chetram, M.A.; Odero-Marah, V.; Hinton, C.V. Loss of pten permits cxcr4-mediated tumorigenesis through erk1/2 in prostate cancer cells. Mol. Cancer Res. 2010, doi:10.1158/1541-7786.MCR-10-0235.
    • (2010) Mol. Cancer Res.
    • Chetram, M.A.1    Odero-Marah, V.2    Hinton, C.V.3
  • 35
    • 69449096661 scopus 로고    scopus 로고
    • Induction of kruppel-like factor 5 expression by androgens results in increased cxcr4-dependent migration of prostate cancer cells in vitro
    • Frigo, D.E.; Sherk, A.B.; Wittmann, B.M.; Norris, J.D.; Wang, Q.; Joseph, J.D.; Toner, A.P.; Brown, M.; McDonnell, D.P. Induction of kruppel-like factor 5 expression by androgens results in increased cxcr4-dependent migration of prostate cancer cells in vitro. Mol. Endocrinol. 2009, 23, 1385-1396.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 1385-1396
    • Frigo, D.E.1    Sherk, A.B.2    Wittmann, B.M.3    Norris, J.D.4    Wang, Q.5    Joseph, J.D.6    Toner, A.P.7    Brown, M.8    McDonnell, D.P.9
  • 36
    • 0037085938 scopus 로고    scopus 로고
    • Use of the stromal cell-derived factor-1/cxcr4 pathway in prostate cancer metastasis to bone
    • Taichman, R.S.; Cooper, C.; Keller, E.T.; Pienta, K.J.; Taichman, N.S.; McCauley, L.K. Use of the stromal cell-derived factor-1/cxcr4 pathway in prostate cancer metastasis to bone. Cancer Res. 2002, 62, 1832-1837.
    • (2002) Cancer Res. , vol.62 , pp. 1832-1837
    • Taichman, R.S.1    Cooper, C.2    Keller, E.T.3    Pienta, K.J.4    Taichman, N.S.5    McCauley, L.K.6
  • 37
    • 27544494623 scopus 로고    scopus 로고
    • Up-regulation of cxcr4 expression in pc-3 cells by stromal-derived factor-1alpha (cxcl12) increases endothelial adhesion and transendothelial migration: Role of mek/erk signaling pathway-dependent nf-kappab activation
    • Kukreja, P.; Abdel-Mageed, A.B.; Mondal, D.; Liu, K.; Agrawal, K.C. Up-regulation of cxcr4 expression in pc-3 cells by stromal-derived factor-1alpha (cxcl12) increases endothelial adhesion and transendothelial migration: Role of mek/erk signaling pathway-dependent nf-kappab activation. Cancer Res. 2005, 65, 9891-9898.
    • (2005) Cancer Res. , vol.65 , pp. 9891-9898
    • Kukreja, P.1    Abdel-Mageed, A.B.2    Mondal, D.3    Liu, K.4    Agrawal, K.C.5
  • 39
    • 33845769269 scopus 로고    scopus 로고
    • Expression and activation of alpha v beta 3 integrins by sdf-1 /cxc 12 increases the aggressiveness of prostate cancer cells
    • Sun, Y.X.; Fang, M.; Wang, J.; Cooper, C.R.; Pienta, K.J.; Taichman, R.S. Expression and activation of alpha v beta 3 integrins by sdf-1 /cxc 12 increases the aggressiveness of prostate cancer cells. Prostate 2007, 67, 61-73.
    • (2007) Prostate , vol.67 , pp. 61-73
    • Sun, Y.X.1    Fang, M.2    Wang, J.3    Cooper, C.R.4    Pienta, K.J.5    Taichman, R.S.6
  • 41
    • 56449111353 scopus 로고    scopus 로고
    • Tumor cell-specific blockade of cxcr4/sdf-1 interactions in prostate cancer cells by htert promoter induced cxcr4 knockdown: A possible metastasis preventing and minimizing approach
    • Xing, Y.; Liu, M.; Du, Y.; Qu, F.; Li, Y.; Zhang, Q.; Xiao, Y.; Zhao, J.; Zeng, F.; Xiao, C. Tumor cell-specific blockade of cxcr4/sdf-1 interactions in prostate cancer cells by htert promoter induced cxcr4 knockdown: A possible metastasis preventing and minimizing approach. Cancer Biol. Ther. 2008, 7, 1839-1848.
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 1839-1848
    • Xing, Y.1    Liu, M.2    Du, Y.3    Qu, F.4    Li, Y.5    Zhang, Q.6    Xiao, Y.7    Zhao, J.8    Zeng, F.9    Xiao, C.10
  • 49
    • 78049487451 scopus 로고    scopus 로고
    • Overlapping and distinct role of cxcr7-sdf-1/itac and cxcr4-sdf-1 axes in regulating metastatic behavior of human rhabdomyosarcomas
    • Grymula, K.; Tarnowski, M.; Wysoczynski, M.; Drukala, J.; Barr, F.G.; Ratajczak, J.; Kucia, M.; Ratajczak, M.Z. Overlapping and distinct role of cxcr7-sdf-1/itac and cxcr4-sdf-1 axes in regulating metastatic behavior of human rhabdomyosarcomas. Int. J. Cancer 2010, 127, 2554-2568.
    • (2010) Int. J. Cancer , vol.127 , pp. 2554-2568
    • Grymula, K.1    Tarnowski, M.2    Wysoczynski, M.3    Drukala, J.4    Barr, F.G.5    Ratajczak, J.6    Kucia, M.7    Ratajczak, M.Z.8
  • 51
    • 18244381261 scopus 로고    scopus 로고
    • Distribution and kinetics of sr-psox/cxcl16 and cxcr6 expression on human dendritic cell subsets and cd4+ t cells
    • Tabata, S.; Kadowaki, N.; Kitawaki, T.; Shimaoka, T.; Yonehara, S.; Yoshie, O.; Uchiyama, T. Distribution and kinetics of sr-psox/cxcl16 and cxcr6 expression on human dendritic cell subsets and cd4+ t cells. J. Leukoc. Biol. 2005, 77, 777-786.
    • (2005) J. Leukoc. Biol. , vol.77 , pp. 777-786
    • Tabata, S.1    Kadowaki, N.2    Kitawaki, T.3    Shimaoka, T.4    Yonehara, S.5    Yoshie, O.6    Uchiyama, T.7
  • 52
    • 0037307794 scopus 로고    scopus 로고
    • Cutting edge: Profile of chemokine receptor expression on human plasma cells accounts for their efficient recruitment to target tissues
    • Nakayama, T.; Hieshima, K.; Izawa, D.; Tatsumi, Y.; Kanamaru, A.; Yoshie, O. Cutting edge: Profile of chemokine receptor expression on human plasma cells accounts for their efficient recruitment to target tissues. J. Immunol. 2003, 170, 1136-1140.
    • (2003) J. Immunol. , vol.170 , pp. 1136-1140
    • Nakayama, T.1    Hieshima, K.2    Izawa, D.3    Tatsumi, Y.4    Kanamaru, A.5    Yoshie, O.6
  • 53
    • 44449175217 scopus 로고    scopus 로고
    • Cxcr6 is expressed in human prostate cancer in vivo and is involved in the in vitro invasion of pc3 and lncap cells
    • Hu, W.; Zhen, X.; Xiong, B.; Wang, B.; Zhang, W.; Zhou, W. Cxcr6 is expressed in human prostate cancer in vivo and is involved in the in vitro invasion of pc3 and lncap cells. Cancer Sci. 2008, 99, 1362-1369.
    • (2008) Cancer Sci. , vol.99 , pp. 1362-1369
    • Hu, W.1    Zhen, X.2    Xiong, B.3    Wang, B.4    Zhang, W.5    Zhou, W.6
  • 55
    • 57749119410 scopus 로고    scopus 로고
    • Cxcr6 induces prostate cancer progression by the akt/mammalian target of rapamycin signaling pathway
    • Wang, J.; Lu, Y.; Koch, A.E.; Zhang, J.; Taichman, R.S. Cxcr6 induces prostate cancer progression by the akt/mammalian target of rapamycin signaling pathway. Cancer Res. 2008, 68, 10367-10376.
    • (2008) Cancer Res. , vol.68 , pp. 10367-10376
    • Wang, J.1    Lu, Y.2    Koch, A.E.3    Zhang, J.4    Taichman, R.S.5
  • 56
    • 0032864675 scopus 로고    scopus 로고
    • Mmp inhibition in prostate cancer
    • Lokeshwar, B.L. Mmp inhibition in prostate cancer. Ann. N. Y. Acad. Sci. 1999, 878, 271-289.
    • (1999) Ann. N. Y. Acad. Sci. , vol.878 , pp. 271-289
    • Lokeshwar, B.L.1
  • 58
    • 0029826978 scopus 로고    scopus 로고
    • Enhanced expression of parathyroid hormone-related protein in prostate cancer as compared with benign prostatic hyperplasia
    • Asadi, F.; Farraj, M.; Sharifi, R.; Malakouti, S.; Antar, S.; Kukreja, S. Enhanced expression of parathyroid hormone-related protein in prostate cancer as compared with benign prostatic hyperplasia. Hum. Pathol. 1996, 27, 1319-1323.
    • (1996) Hum. Pathol. , vol.27 , pp. 1319-1323
    • Asadi, F.1    Farraj, M.2    Sharifi, R.3    Malakouti, S.4    Antar, S.5    Kukreja, S.6
  • 60
    • 0043244928 scopus 로고    scopus 로고
    • Intra-tibial injection of human prostate cancer cell line cwr22 elicits osteoblastic response in immunodeficient rats
    • Andersen, C.; Bagi, C.M.; Adams, S.W. Intra-tibial injection of human prostate cancer cell line cwr22 elicits osteoblastic response in immunodeficient rats. J. Musculoskelet Neuronal. Interact. 2003, 3, 148-155.
    • (2003) J. Musculoskelet Neuronal. Interact. , vol.3 , pp. 148-155
    • Andersen, C.1    Bagi, C.M.2    Adams, S.W.3
  • 62
    • 0023025173 scopus 로고
    • Establishment and characterization of seven dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers
    • Isaacs, J.T.; Isaacs, W.B.; Feitz, W.F.; Scheres, J. Establishment and characterization of seven dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers. Prostate 1986, 9, 261-281.
    • (1986) Prostate , vol.9 , pp. 261-281
    • Isaacs, J.T.1    Isaacs, W.B.2    Feitz, W.F.3    Scheres, J.4
  • 64
    • 35648970538 scopus 로고    scopus 로고
    • Activation of the ralgef/ral pathway promotes prostate cancer metastasis to bone
    • Yin, J.; Pollock, C.; Tracy, K.; Chock, M.; Martin, P.; Oberst, M.; Kelly, K. Activation of the ralgef/ral pathway promotes prostate cancer metastasis to bone. Mol. Cell Biol. 2007, 27, 7538-7550.
    • (2007) Mol. Cell Biol. , vol.27 , pp. 7538-7550
    • Yin, J.1    Pollock, C.2    Tracy, K.3    Chock, M.4    Martin, P.5    Oberst, M.6    Kelly, K.7
  • 69
    • 34248160630 scopus 로고    scopus 로고
    • Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model
    • Hsieh, C.L.; Xie, Z.; Yu, J.; Martin, W.D.; Datta, M.W.; Wu, G.J.; Chung, L.W. Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model. Prostate 2007, 67, 685-691.
    • (2007) Prostate , vol.67 , pp. 685-691
    • Hsieh, C.L.1    Xie, Z.2    Yu, J.3    Martin, W.D.4    Datta, M.W.5    Wu, G.J.6    Chung, L.W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.