Is a regenerative approach viable for the treatment of COPD?

British Journal of Pharmacology

Volumn 163, Issue 1, 2011, Pages 106-115

  Hind, Matthew ^a   Maden, Malcolm ^b  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

COPD; emphysema; ES cells; lung regeneration; MSCs; novel therapies; retinoic acid

Indexed keywords

ACTIVIN; ADRENOMEDULLIN; ALPHA 1 ANTITRYPSIN; ANTIINFLAMMATORY AGENT; BLEOMYCIN; CORTICOSTEROID; ESTROGEN; FIBROBLAST GROWTH FACTOR 2; GRANULOCYTE COLONY STIMULATING FACTOR; ISOTRETINOIN; KERATINOCYTE GROWTH FACTOR; MATRIX METALLOPROTEINASE; PALOVAROTENE; PLACEBO; RETINAL DEHYDROGENASE; RETINOIC ACID; RETINOID; RETINOL; SCATTER FACTOR; WNT3A PROTEIN;

ANTIINFLAMMATORY ACTIVITY; ASTHMA; CELL DESTRUCTION; CELL HYPERPLASIA; CELL REGENERATION; CELL RENEWAL; CELL THERAPY; CHRONIC BRONCHITIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL FEATURE; CLINICAL TRIAL (TOPIC); DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG ERUPTION; DRUG INDUCED HEADACHE; DRUG MEGADOSE; DYSLIPIDEMIA; EMPHYSEMA; ENZYME SYNTHESIS; GENETIC SUSCEPTIBILITY; GENETIC TRANSFECTION; GOBLET CELL; HUMAN; HYPERTRANSAMINASEMIA; INTRACELLULAR SIGNALING; LOW DRUG DOSE; LUNG ALVEOLUS CELL; LUNG FUNCTION; LUNG INJURY; LUNG STRUCTURE; LUNG TRANSPLANTATION; MESENCHYMAL STEM CELL TRANSPLANTATION; MORBIDITY; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PARACRINE SIGNALING; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; REGENERATIVE ABILITY; REGENERATIVE MEDICINE; REGULATORY MECHANISM; REVIEW; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING; TISSUE REGENERATION;

ANIMALS; CLINICAL TRIALS AS TOPIC; HUMANS; LUNG; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REGENERATION;

EID: 79953713688     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01246.x     Document Type: Review

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