Function of alcohol dehydrogenase and aldehyde dehydrogenase gene families in retinoid signaling

Advances in Experimental Medicine and Biology

Volumn 463, Issue , 1999, Pages 311-319

  Duester, G ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; RETINOID;

CONFERENCE PAPER; EMBRYO; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SPECIFICITY; MULTIGENE FAMILY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VITAMIN METABOLISM; XENOPUS LAEVIS;

XENOPUS LAEVIS;

EID: 0033282481     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-4735-8_38     Document Type: Conference Paper

References (53)

1. Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression
2. Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis
3. Initiation of retinoid signaling in primitive streak mouse embryos: Spatiotemporal expression patterns of receptors and metabolic enzymes for ligand synthesis
4. Retinol and retinoic acid metabolism
5. Novel retinoic acid receptor ligands in Xenopus embryos
6. An essential role for retinoid signaling in anteroposterior neural patterning
7. Physiological substrates for rat alcohol dehydrogenase classes: Aldehydes of lipid peroxidation, omega-hydroxyfatty acids, and retinoids
8. Biotransformation of all-trans-retinol and all-trans-retinal to all-trans-retinoic acid in rat conceptal homogenates
9. Enzymatic conversion of retinaldehyde to retinoic acid by cloned murine cytosolic and mitochondrial aldehyde dehydrogenases
10. A concentration gradient of retinoids in the early Xenopus laevis embryo
11. Terminal-group oxidation of retinol by mouse epidermis: Inhibition in vitro and in vivo
12. The retinoid X receptor ligand, 9-cis-retinoic acid, is a potential regulator of early Xenopus development
13. Temporal distribution, localization and metabolism of all-trans-retinol, didehydroretinol and all-trans-retinal during Xenopus development
14. Ethanol inhibition of retinoic acid synthesis as a potential mechanism for fetal alcohol syndrome
15. Localization of class I and class IV alcohol dehydrogenases in mouse testis and epididymis: Potential retinol dehydrogenases for endogenous retinoic acid synthesis
16. Temporally-regulated retinoic acid depletion produces specific neural crest, ocular and nervous system defects
17. Identification of human liver aldehyde dehydrogenases that catalyze the oxidation of aldophosphamide and retinaldehyde
18. Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis
19. Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis
20. Retinoic acid causes an anteroposterior transformation in the developing central nervous system
21. Three-dimensional structure of horse liver alcohol dehydrogenase at 2.4 Å resolution
22. Enzymatic oxidation of vitamin A aldehyde to vitamin A acid
23. Retinoic acid and alcohol/retinol dehydrogenase in the mouse adrenal gland: A potential endocrine source of retinoic acid during development
24. Class IV alcohol/retinol dehydrogenase localization in epidermal basal layer: Potential site of retinoic acid synthesis during skin development
25. Regional restriction of alcohol/retinol dehydrogenases along the mouse gastrointestinal epithelium
26. Retinoids in development
27. Structure of human beta 1 alcohol dehydrogenase: Catalytic effects of non-active-site substitutions
28. The retinal and 3-dehydroretinal in Xenopus laevis eggs are bound to lipovitellin 1 by a Schiff base linkage
29. Role of nuclear retinoic acid receptors in the regulation of gene expression
30. Xenopus laevis: A model system for the study of embryonic retinoid metabolism: 1. Embryonic metabolism of 9-cis- and all-trans-retinals and retinols to their corresponding acid forms
31. Identification of mouse liver aldehyde dehydrogenases that catalyze the oxidation of retinaldehyde to retinoic acid
32. The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold
33. Role of retinoids in embryonic development
34. Vitamin A-deficient quail embryos have half a hindbrain and other neural detects
35. The retinoid receptors
36. Asymmetrical retinoic acid synthesis in the dorsoventral axis of the retina
37. Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development
38. Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis
39. Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos
40. v-erbA and citral reduce the teratogenic effects of all-trans retinoic acid and retinol, respectively, in Xenopus embryogenesis
41. Retinoid receptors promote primary neurogenesis in Xenopus
42. Identification of a retinoic acid-sensitive period during primary axis formation in Xenopus laevis
43. Structure of mitochondrial aldehyde dehydrogenase: The genetic component of ethanol aversion
44. Mouse class 3 aldehyde dehydrogenases
45. Mouse microsomal class 3 aldehyde dehydrogenase: AHD3 cDNA sequence, inducibility by dioxin and clofibrate, and genetic mapping
46. Regional differences in retinoid release from embryonic neural tissue detected by an in vitro reporter assay
47. Cloning of a cDNA encoding an aldehyde dehydrogenase and its expression in Escherichia coli - Recognition of retinal as substrate
48. X-ray structure of human class IV sigma alcohol dehydrogenase - Structural basis for substrate specificity
49. Catalytic efficiency of human alcohol dehydrogenases for retinol oxidation and retinal reduction
50. Structure of human chi alcohol dehydrogenase: A glutathione-dependent formaldehyde dehydrogenase
51. Human aldehyde dehydrogenase gene family
52. Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family
53. Molecular identification of a major retinoic-acid-synthesizing enzyme, a retinaldehyde-specific dehydrogenase