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Volumn 181, Issue , 2011, Pages 67-78

Modeling of presymptomatic and symptomatic stages of parkinsonism in mice

Author keywords

1 methyl 4 phenyl 1,2,3,6 tetrahydropyridine; Brain; Dopamine; Mice; Nigrostriatal system; Parkinsonism

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; DOPAMINE;

EID: 79953711110     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.03.006     Document Type: Article
Times cited : (6)

References (76)
  • 1
    • 84914639435 scopus 로고
    • Estimation of nuclear population from microtome sections
    • Abercrombie M. Estimation of nuclear population from microtome sections. Anat Res 1946, 94:239-247.
    • (1946) Anat Res , vol.94 , pp. 239-247
    • Abercrombie, M.1
  • 2
    • 0025893945 scopus 로고
    • Parkinson's disease: pathophysiology
    • Agid Y. Parkinson's disease: pathophysiology. Lancet 1991, 337:1321-1324.
    • (1991) Lancet , vol.337 , pp. 1321-1324
    • Agid, Y.1
  • 3
    • 0024450903 scopus 로고
    • The functional anatomy of basal ganglia disorders
    • Albin R.L., Young A.B., Penney J.B. The functional anatomy of basal ganglia disorders. Trends Neurosci 1989, 12:366-375.
    • (1989) Trends Neurosci , vol.12 , pp. 366-375
    • Albin, R.L.1    Young, A.B.2    Penney, J.B.3
  • 4
    • 0021170352 scopus 로고
    • Ultrastructural morphology of dopaminergic nerve terminals and synapses in the striatum of the rat using tyrosine hydroxylase immunocytochemistry: a topographical study
    • Arluison M., Dietl M., Thibault J. Ultrastructural morphology of dopaminergic nerve terminals and synapses in the striatum of the rat using tyrosine hydroxylase immunocytochemistry: a topographical study. Brain Res Bull 1984, 13:269-285.
    • (1984) Brain Res Bull , vol.13 , pp. 269-285
    • Arluison, M.1    Dietl, M.2    Thibault, J.3
  • 5
    • 0034961813 scopus 로고    scopus 로고
    • Subclinical dopaminergic dysfunction in asymptomatic Parkinson's disease patients' relatives with a decreased sense of smell
    • Berendse H.W., Booij J., Francot C.M., Bergmans P.L., Hijman R., Stoof J.C., Wolters E.C. Subclinical dopaminergic dysfunction in asymptomatic Parkinson's disease patients' relatives with a decreased sense of smell. Ann Neurol 2001, 50:34-41.
    • (2001) Ann Neurol , vol.50 , pp. 34-41
    • Berendse, H.W.1    Booij, J.2    Francot, C.M.3    Bergmans, P.L.4    Hijman, R.5    Stoof, J.C.6    Wolters, E.C.7
  • 6
    • 0344442860 scopus 로고    scopus 로고
    • "Passive stabilization" of striatal extracellular dopamine across the lesion spectrum encompassing the presymptomatic phase of Parkinson's disease: a voltammetric study in the 6-OHDA-lesioned rat
    • Bergstrom B.P., Garris P.A. "Passive stabilization" of striatal extracellular dopamine across the lesion spectrum encompassing the presymptomatic phase of Parkinson's disease: a voltammetric study in the 6-OHDA-lesioned rat. J Neurochem 2003, 87:1224-1236.
    • (2003) J Neurochem , vol.87 , pp. 1224-1236
    • Bergstrom, B.P.1    Garris, P.A.2
  • 7
    • 0015745743 scopus 로고
    • Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations
    • Bernheimer H., Birkmayer W., Hornykiewicz O., Jellinger K., Seitelberger F. Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations. J Neurol Sci 1973, 20:415-455.
    • (1973) J Neurol Sci , vol.20 , pp. 415-455
    • Bernheimer, H.1    Birkmayer, W.2    Hornykiewicz, O.3    Jellinger, K.4    Seitelberger, F.5
  • 8
    • 77957132859 scopus 로고    scopus 로고
    • Neuroprotection for Parkinson's disease: clinically driven experimental design in non-human primates
    • Elsevier, Amsterdam, R. Nass, S. Przedborski (Eds.)
    • Bezard E. Neuroprotection for Parkinson's disease: clinically driven experimental design in non-human primates. Parkinson's disease: molecular and therapeutic insights from model systems 2008, 65-76. Elsevier, Amsterdam. R. Nass, S. Przedborski (Eds.).
    • (2008) Parkinson's disease: molecular and therapeutic insights from model systems , pp. 65-76
    • Bezard, E.1
  • 9
    • 0030770812 scopus 로고    scopus 로고
    • Kinetics of nigral degeneration in a chronic model of MPTP-treated mice
    • Bezard E., Dovero S., Bioulac B., Gross C.E. Kinetics of nigral degeneration in a chronic model of MPTP-treated mice. Neurosci Lett 1997, 234:47-50.
    • (1997) Neurosci Lett , vol.234 , pp. 47-50
    • Bezard, E.1    Dovero, S.2    Bioulac, B.3    Gross, C.E.4
  • 10
    • 0035449393 scopus 로고    scopus 로고
    • Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease
    • Bezard E., Dovero S., Prunier C., Ravenscroft P., Chalon S., Guilloteau D., Crossman A.R., Bioulac B., Brotchie J.M., Gross C.E. Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease. J Neurosci 2001, 21:6853-6861.
    • (2001) J Neurosci , vol.21 , pp. 6853-6861
    • Bezard, E.1    Dovero, S.2    Prunier, C.3    Ravenscroft, P.4    Chalon, S.5    Guilloteau, D.6    Crossman, A.R.7    Bioulac, B.8    Brotchie, J.M.9    Gross, C.E.10
  • 11
    • 0031960890 scopus 로고    scopus 로고
    • Compensatory mechanisms in experimental and human parkinsonism: towards a dynamic approach
    • Bezard E., Gross C.E. Compensatory mechanisms in experimental and human parkinsonism: towards a dynamic approach. Prog Neurobiol 1998, 55:93-116.
    • (1998) Prog Neurobiol , vol.55 , pp. 93-116
    • Bezard, E.1    Gross, C.E.2
  • 12
    • 0037384803 scopus 로고    scopus 로고
    • Presymptomatic compensation in Parkinson's disease is not dopamine-mediated
    • Bezard E., Gross C.E., Brotchie J.M. Presymptomatic compensation in Parkinson's disease is not dopamine-mediated. Trends Neurosci 2003, 26:215-221.
    • (2003) Trends Neurosci , vol.26 , pp. 215-221
    • Bezard, E.1    Gross, C.E.2    Brotchie, J.M.3
  • 13
    • 0033811169 scopus 로고    scopus 로고
    • Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse
    • Bezard E., Jaber M., Gonon F., Boireau A., Bloch B., Gross C.E. Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse. Eur J Neurosci 2000, 12:2892-2900.
    • (2000) Eur J Neurosci , vol.12 , pp. 2892-2900
    • Bezard, E.1    Jaber, M.2    Gonon, F.3    Boireau, A.4    Bloch, B.5    Gross, C.E.6
  • 18
    • 0242363668 scopus 로고    scopus 로고
    • Looking backward to move forward: early detection of neurodegenerative disorders
    • DeKosky S.T., Marek K. Looking backward to move forward: early detection of neurodegenerative disorders. Science 2003, 302:830-834.
    • (2003) Science , vol.302 , pp. 830-834
    • DeKosky, S.T.1    Marek, K.2
  • 19
    • 34250928307 scopus 로고
    • Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system
    • Ehringer H., Hornykiewicz O. Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system. Klin Wochenschr 1960, 38:1236-1239.
    • (1960) Klin Wochenschr , vol.38 , pp. 1236-1239
    • Ehringer, H.1    Hornykiewicz, O.2
  • 20
    • 70349731404 scopus 로고    scopus 로고
    • Biological fluid biomarkers in neurodegenerative parkinsonism
    • Eller M., Williams D.R. Biological fluid biomarkers in neurodegenerative parkinsonism. Nat Rev Neurol 2009, 5:561-570.
    • (2009) Nat Rev Neurol , vol.5 , pp. 561-570
    • Eller, M.1    Williams, D.R.2
  • 21
    • 58349102182 scopus 로고    scopus 로고
    • How do you treat motor complications in Parkinson's disease: medicine, surgery, or both?
    • Fahn S. How do you treat motor complications in Parkinson's disease: medicine, surgery, or both?. Ann Neurol 2008, 64(Suppl 2):S56-S64.
    • (2008) Ann Neurol , vol.64 , Issue.SUPPL 2
    • Fahn, S.1
  • 22
    • 0023481972 scopus 로고
    • The neostriatal mosaic: II. Patch- and matrix-directed mesostriatal dopaminergic and non-dopaminergic systems
    • Gerfen M., Herkenham M., Thibault J. The neostriatal mosaic: II. Patch- and matrix-directed mesostriatal dopaminergic and non-dopaminergic systems. J Neurosci 1987, 7:3915-3934.
    • (1987) J Neurosci , vol.7 , pp. 3915-3934
    • Gerfen, M.1    Herkenham, M.2    Thibault, J.3
  • 23
    • 0029845140 scopus 로고    scopus 로고
    • Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man
    • Gerlach M., Riederer P. Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man. J Neural Transm 1996, 103:987-1041.
    • (1996) J Neural Transm , vol.103 , pp. 987-1041
    • Gerlach, M.1    Riederer, P.2
  • 24
    • 65549105080 scopus 로고    scopus 로고
    • Differences between subacute and chronic MPTP mice models: investigation of dopaminergic neuronal degeneration and alpha-synuclein inclusions
    • Gibrat C., Saint-Pierre M., Bousquet M., Levesque D., Rouillard C., Cicchetti F. Differences between subacute and chronic MPTP mice models: investigation of dopaminergic neuronal degeneration and alpha-synuclein inclusions. J Neurochem 2009, 109:1469-1482.
    • (2009) J Neurochem , vol.109 , pp. 1469-1482
    • Gibrat, C.1    Saint-Pierre, M.2    Bousquet, M.3    Levesque, D.4    Rouillard, C.5    Cicchetti, F.6
  • 25
    • 10344228794 scopus 로고    scopus 로고
    • Quantification and pharmacological characterization of dialysate levels of noradrenaline in the striatum of freely-moving rats: release from adrenergic terminals and modulation by alpha2-autoreceptors
    • Gobert A., Billiras R., Cistarelli L., Millan M.J. Quantification and pharmacological characterization of dialysate levels of noradrenaline in the striatum of freely-moving rats: release from adrenergic terminals and modulation by alpha2-autoreceptors. J Neurosci Methods 2004, 140:141-152.
    • (2004) J Neurosci Methods , vol.140 , pp. 141-152
    • Gobert, A.1    Billiras, R.2    Cistarelli, L.3    Millan, M.J.4
  • 29
    • 0025099780 scopus 로고
    • Loss of brainstem serotonin- and substance P-containing neurons in Parkinson's disease
    • Halliday G.M., Blumbergs P.C., Cotton R.G., Blessing W.W., Geffen L.B. Loss of brainstem serotonin- and substance P-containing neurons in Parkinson's disease. Brain Res 1990, 510:104-107.
    • (1990) Brain Res , vol.510 , pp. 104-107
    • Halliday, G.M.1    Blumbergs, P.C.2    Cotton, R.G.3    Blessing, W.W.4    Geffen, L.B.5
  • 30
    • 0026089919 scopus 로고
    • Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study
    • Herkenham M., Little M.D., Bankiewicz K., Yang S.C., Markey S.P., Johannessen J.N. Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study. Neuroscience 1991, 40:133-158.
    • (1991) Neuroscience , vol.40 , pp. 133-158
    • Herkenham, M.1    Little, M.D.2    Bankiewicz, K.3    Yang, S.C.4    Markey, S.P.5    Johannessen, J.N.6
  • 31
    • 0032145369 scopus 로고    scopus 로고
    • Induction of interleukin-1 associated with compensatory dopaminergic sprouting in the denervated striatum of young mice: model of aging and neurodegenerative disease
    • Ho A., Blum M. Induction of interleukin-1 associated with compensatory dopaminergic sprouting in the denervated striatum of young mice: model of aging and neurodegenerative disease. J Neurosci 1998, 18:5614-5629.
    • (1998) J Neurosci , vol.18 , pp. 5614-5629
    • Ho, A.1    Blum, M.2
  • 32
    • 58649119076 scopus 로고    scopus 로고
    • The influence of catecholamine on the migration of gonadotropin-releasing hormone-producing neurons in the rat foetuses
    • Izvolskaia M., Duittoz A.H., Tillet Y., Ugrumov M.V. The influence of catecholamine on the migration of gonadotropin-releasing hormone-producing neurons in the rat foetuses. Brain Struct Funct 2009, 213:289-300.
    • (2009) Brain Struct Funct , vol.213 , pp. 289-300
    • Izvolskaia, M.1    Duittoz, A.H.2    Tillet, Y.3    Ugrumov, M.V.4
  • 33
    • 0028784523 scopus 로고
    • Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Jackson-Lewis V., Jakowec M., Burke R.E., Przedborski S. Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neurodegeneration 1995, 4:257-269.
    • (1995) Neurodegeneration , vol.4 , pp. 257-269
    • Jackson-Lewis, V.1    Jakowec, M.2    Burke, R.E.3    Przedborski, S.4
  • 34
    • 34347259269 scopus 로고    scopus 로고
    • Protocol for the MPTP mouse model of Parkinson's disease
    • Jackson-Lewis V., Przedborski S. Protocol for the MPTP mouse model of Parkinson's disease. Nat Protoc 2007, 2:141-151.
    • (2007) Nat Protoc , vol.2 , pp. 141-151
    • Jackson-Lewis, V.1    Przedborski, S.2
  • 35
  • 37
    • 0038171270 scopus 로고    scopus 로고
    • Role of dopamine transporter against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice
    • Kurosaki R., Muramatsu Y., Watanabe H., Michimata M., Matsubara M., Imai Y., Araki T. Role of dopamine transporter against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice. Metab Brain Dis 2003, 18:139-146.
    • (2003) Metab Brain Dis , vol.18 , pp. 139-146
    • Kurosaki, R.1    Muramatsu, Y.2    Watanabe, H.3    Michimata, M.4    Matsubara, M.5    Imai, Y.6    Araki, T.7
  • 38
    • 0021337873 scopus 로고
    • Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey
    • Langston J.W., Forno L.S., Rebert C.S., Irwin I. Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey. Brain Res 1984, 292:390-394.
    • (1984) Brain Res , vol.292 , pp. 390-394
    • Langston, J.W.1    Forno, L.S.2    Rebert, C.S.3    Irwin, I.4
  • 39
    • 0033020233 scopus 로고    scopus 로고
    • Effects of cerebrospinal fluid from patients with Parkinson disease on dopaminergic cells
    • Le W.D., Rowe D.B., Jankovic J., Xie W., Appel S.H. Effects of cerebrospinal fluid from patients with Parkinson disease on dopaminergic cells. Arch Neurol 1999, 56:194-200.
    • (1999) Arch Neurol , vol.56 , pp. 194-200
    • Le, W.D.1    Rowe, D.B.2    Jankovic, J.3    Xie, W.4    Appel, S.H.5
  • 40
    • 0023620322 scopus 로고
    • Acute ultrastructural and behavioral effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice
    • Linder J.C., Klemfuss H., Groves P.M. Acute ultrastructural and behavioral effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice. Neurosci Lett 1987, 82:221-226.
    • (1987) Neurosci Lett , vol.82 , pp. 221-226
    • Linder, J.C.1    Klemfuss, H.2    Groves, P.M.3
  • 41
    • 0021137683 scopus 로고
    • Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism
    • Markey S.P., Johannessen J.N., Chiueh C.C., Burns R.S., Herkenham M.A. Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism. Nature 1984, 311:464-467.
    • (1984) Nature , vol.311 , pp. 464-467
    • Markey, S.P.1    Johannessen, J.N.2    Chiueh, C.C.3    Burns, R.S.4    Herkenham, M.A.5
  • 42
    • 0033605337 scopus 로고    scopus 로고
    • An endogenous MPTP-like dopaminergic neurotoxin, N-methyl(R)salsolinol, in the cerebrospinal fluid decreases with progression of Parkinson's disease
    • Maruyama W., Abe T., Tohgi H., Naoi M. An endogenous MPTP-like dopaminergic neurotoxin, N-methyl(R)salsolinol, in the cerebrospinal fluid decreases with progression of Parkinson's disease. Neurosci Lett 1999, 262:13-16.
    • (1999) Neurosci Lett , vol.262 , pp. 13-16
    • Maruyama, W.1    Abe, T.2    Tohgi, H.3    Naoi, M.4
  • 43
    • 0026753805 scopus 로고
    • N-methylation of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (R)-salsolinol, in rat brains: in vivo microdialysis study
    • Maruyama W., Nakahara D., Ota M., Takahashi T., Takahashi A., Nagatsu T., Naoi M. N-methylation of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (R)-salsolinol, in rat brains: in vivo microdialysis study. J Neurochem 1992, 59:395-400.
    • (1992) J Neurochem , vol.59 , pp. 395-400
    • Maruyama, W.1    Nakahara, D.2    Ota, M.3    Takahashi, T.4    Takahashi, A.5    Nagatsu, T.6    Naoi, M.7
  • 45
    • 2142640816 scopus 로고    scopus 로고
    • Neuroprotective strategies for Parkinson's disease: conceptual limits of animal models and clinical trials
    • Meissner W., Hill M.P., Tison F., Gross C.E., Bezard E. Neuroprotective strategies for Parkinson's disease: conceptual limits of animal models and clinical trials. Trends Pharmacol Sci 2004, 25:249-253.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 249-253
    • Meissner, W.1    Hill, M.P.2    Tison, F.3    Gross, C.E.4    Bezard, E.5
  • 46
    • 0030840624 scopus 로고    scopus 로고
    • Isoquinoline neurotoxins in the brain and Parkinson's disease
    • Nagatsu T. Isoquinoline neurotoxins in the brain and Parkinson's disease. Neurosci Res 1997, 29:99-111.
    • (1997) Neurosci Res , vol.29 , pp. 99-111
    • Nagatsu, T.1
  • 47
    • 0032561740 scopus 로고    scopus 로고
    • Differential time courses of exogenous 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine and its metabolite MPP+ in the rat striatum and nucleus accumbens measured using in vivo voltammetry
    • Nakazato T., Akiyama A. Differential time courses of exogenous 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine and its metabolite MPP+ in the rat striatum and nucleus accumbens measured using in vivo voltammetry. Brain Res 1998, 812:150-156.
    • (1998) Brain Res , vol.812 , pp. 150-156
    • Nakazato, T.1    Akiyama, A.2
  • 48
    • 0034676515 scopus 로고    scopus 로고
    • Apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, in dopamine neurons
    • Naoi M., Maruyama W., Akao Y., Zhang J., Parvez H. Apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, in dopamine neurons. Toxicology 2000, 153:123-141.
    • (2000) Toxicology , vol.153 , pp. 123-141
    • Naoi, M.1    Maruyama, W.2    Akao, Y.3    Zhang, J.4    Parvez, H.5
  • 49
    • 0030614651 scopus 로고    scopus 로고
    • N-methyl-(R)salsolinol as a dopaminergic neurotoxin: from an animal model to an early marker of Parkinson's disease
    • Naoi M., Maruyama W., Dostert P., Hashizume Y. N-methyl-(R)salsolinol as a dopaminergic neurotoxin: from an animal model to an early marker of Parkinson's disease. J Neural Transm Suppl 1997, 50:89-105.
    • (1997) J Neural Transm Suppl , vol.50 , pp. 89-105
    • Naoi, M.1    Maruyama, W.2    Dostert, P.3    Hashizume, Y.4
  • 50
    • 0029942834 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons in the mouse: computer-assisted mapping
    • Nelson E., Liang C., Sinton C., German D. Midbrain dopaminergic neurons in the mouse: computer-assisted mapping. J Comp Neurol 1996, 369:361-371.
    • (1996) J Comp Neurol , vol.369 , pp. 361-371
    • Nelson, E.1    Liang, C.2    Sinton, C.3    German, D.4
  • 51
    • 0030031457 scopus 로고    scopus 로고
    • The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons
    • Nirenberg M.J., Vaughan R.A., Uhl G.R., Kuhar M.J., Pickel V.M. The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons. J Neurosci 1996, 16:436-447.
    • (1996) J Neurosci , vol.16 , pp. 436-447
    • Nirenberg, M.J.1    Vaughan, R.A.2    Uhl, G.R.3    Kuhar, M.J.4    Pickel, V.M.5
  • 52
    • 0026690270 scopus 로고
    • Endogenous synthesis of N-methylsalsolinol, an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, in rat brain during in vivo microdialysis with salsolinol, as demonstrated by gas chromatography-mass spectrometry
    • Niwa T., Maruyama W., Nakahara D., Takeda N., Yoshizumi H., Tatematsu A., Takahashi A., Dostert P., Naoi M., Nagatsu T. Endogenous synthesis of N-methylsalsolinol, an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, in rat brain during in vivo microdialysis with salsolinol, as demonstrated by gas chromatography-mass spectrometry. J Chromatogr 1992, 578:109-115.
    • (1992) J Chromatogr , vol.578 , pp. 109-115
    • Niwa, T.1    Maruyama, W.2    Nakahara, D.3    Takeda, N.4    Yoshizumi, H.5    Tatematsu, A.6    Takahashi, A.7    Dostert, P.8    Naoi, M.9    Nagatsu, T.10
  • 53
    • 33748609091 scopus 로고    scopus 로고
    • The globus pallidus pars externa and Parkinson's disease. Ready for prime time?
    • Obeso J.A., Rodriguez-Oroz M.C., Javier Blesa F., Guridi J. The globus pallidus pars externa and Parkinson's disease. Ready for prime time?. Exp Neurol 2006, 202:1-7.
    • (2006) Exp Neurol , vol.202 , pp. 1-7
    • Obeso, J.A.1    Rodriguez-Oroz, M.C.2    Javier Blesa, F.3    Guridi, J.4
  • 55
    • 0035960066 scopus 로고    scopus 로고
    • Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment
    • Petroske E., Meredith G.E., Callen S., Totterdell S., Lau Y.S. Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment. Neuroscience 2001, 106:589-601.
    • (2001) Neuroscience , vol.106 , pp. 589-601
    • Petroske, E.1    Meredith, G.E.2    Callen, S.3    Totterdell, S.4    Lau, Y.S.5
  • 57
    • 37549021547 scopus 로고    scopus 로고
    • Preclinical development of gene therapy for Parkinson's disease
    • Porras G., Bezard E. Preclinical development of gene therapy for Parkinson's disease. Exp Neurol 2008, 209:72-81.
    • (2008) Exp Neurol , vol.209 , pp. 72-81
    • Porras, G.1    Bezard, E.2
  • 59
    • 0037012844 scopus 로고    scopus 로고
    • Axonal self-destruction and neurodegeneration
    • Raff M.C., Whitmore A.V., Finn J.T. Axonal self-destruction and neurodegeneration. Science 2002, 296:868-871.
    • (2002) Science , vol.296 , pp. 868-871
    • Raff, M.C.1    Whitmore, A.V.2    Finn, J.T.3
  • 60
    • 0017082987 scopus 로고
    • Time course of nigrostriatal degeneration in Parkinson's disease. A detailed study of influential factors in human brain amine analysis
    • Riederer P., Wuketich S. Time course of nigrostriatal degeneration in Parkinson's disease. A detailed study of influential factors in human brain amine analysis. J Neural Transm 1976, 38:277-301.
    • (1976) J Neural Transm , vol.38 , pp. 277-301
    • Riederer, P.1    Wuketich, S.2
  • 61
    • 56749158302 scopus 로고    scopus 로고
    • JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration
    • Ries V., Silva R.M., Oo T.F., Cheng H.C., Rzhetskaya M., Kholodilov N., Flavell R.A., Kuan C.Y., Rakic P., Burke R.E. JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration. J Neurochem 2008, 107:1578-1588.
    • (2008) J Neurochem , vol.107 , pp. 1578-1588
    • Ries, V.1    Silva, R.M.2    Oo, T.F.3    Cheng, H.C.4    Rzhetskaya, M.5    Kholodilov, N.6    Flavell, R.A.7    Kuan, C.Y.8    Rakic, P.9    Burke, R.E.10
  • 62
    • 0142250855 scopus 로고    scopus 로고
    • Behavioral changes are not directly related to striatal monoamine levels, number of nigral neurons, or dose of parkinsonian toxin MPTP in mice
    • Rousselet E., Joubert C., Callebert J., Parain K., Tremblay L., Orieux G., Launay J.M., Cohen-Salmon C., Hirsch E.C. Behavioral changes are not directly related to striatal monoamine levels, number of nigral neurons, or dose of parkinsonian toxin MPTP in mice. Neurobiol Dis 2003, 14:218-228.
    • (2003) Neurobiol Dis , vol.14 , pp. 218-228
    • Rousselet, E.1    Joubert, C.2    Callebert, J.3    Parain, K.4    Tremblay, L.5    Orieux, G.6    Launay, J.M.7    Cohen-Salmon, C.8    Hirsch, E.C.9
  • 64
    • 0029878953 scopus 로고    scopus 로고
    • Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behaviour disorder
    • Schenck C.H., Bundlie S.R., Mahowald M.W. Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behaviour disorder. Neurology 1996, 46:388-393.
    • (1996) Neurology , vol.46 , pp. 388-393
    • Schenck, C.H.1    Bundlie, S.R.2    Mahowald, M.W.3
  • 65
    • 0035214256 scopus 로고    scopus 로고
    • Neurochemical findings in the MPTP model of Parkinson's disease
    • Schmidt N., Ferger B. Neurochemical findings in the MPTP model of Parkinson's disease. J Neural Transm 2001, 108:1263-1282.
    • (2001) J Neural Transm , vol.108 , pp. 1263-1282
    • Schmidt, N.1    Ferger, B.2
  • 67
    • 0035829368 scopus 로고    scopus 로고
    • Behavioral phenotyping of the MPTP mouse model of Parkinson's disease
    • Sedelis M., Schwarting R.K., Huston J.P. Behavioral phenotyping of the MPTP mouse model of Parkinson's disease. Behav Brain Res 2001, 125:109-125.
    • (2001) Behav Brain Res , vol.125 , pp. 109-125
    • Sedelis, M.1    Schwarting, R.K.2    Huston, J.P.3
  • 68
    • 47049106015 scopus 로고    scopus 로고
    • Chronic intraventricular administration of 1-methyl-4-phenylpyridinium as a progressive model of Parkinson's disease
    • Sonsalla P.K., Zeevalk G.D., German D.C. Chronic intraventricular administration of 1-methyl-4-phenylpyridinium as a progressive model of Parkinson's disease. Parkinsonism Relat Disord 2008, 14(Suppl 2):S116-S118.
    • (2008) Parkinsonism Relat Disord , vol.14 , Issue.SUPPL 2
    • Sonsalla, P.K.1    Zeevalk, G.D.2    German, D.C.3
  • 70
    • 0036447089 scopus 로고    scopus 로고
    • Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Tillerson J.L., Caudle W.M., Reveron M.E., Miller G.W. Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Exp Neurol 2002, 178:80-90.
    • (2002) Exp Neurol , vol.178 , pp. 80-90
    • Tillerson, J.L.1    Caudle, W.M.2    Reveron, M.E.3    Miller, G.W.4
  • 72
    • 0037654372 scopus 로고    scopus 로고
    • Growth-factor gene therapy for neurodegenerative disorders
    • Tuszynski M.H. Growth-factor gene therapy for neurodegenerative disorders. Lancet Neurol 2002, 1:51-57.
    • (2002) Lancet Neurol , vol.1 , pp. 51-57
    • Tuszynski, M.H.1
  • 73
    • 77954292010 scopus 로고    scopus 로고
    • Brain neurons partly expressing monoaminergic phenotype: distribution, development, and functional significance in norm and pathology
    • Springer, New York, S. Vizi (Ed.)
    • Ugrumov M.V. Brain neurons partly expressing monoaminergic phenotype: distribution, development, and functional significance in norm and pathology. Handbook of neurochemistry and molecular neurobiology (Lajtha A, ed), Neurotransmitter systems 2008, 21-73. Springer, New York. S. Vizi (Ed.).
    • (2008) Handbook of neurochemistry and molecular neurobiology (Lajtha A, ed), Neurotransmitter systems , pp. 21-73
    • Ugrumov, M.V.1
  • 74
    • 70350054626 scopus 로고    scopus 로고
    • Non-dopaminergic neurons partly expressing dopaminergic phenotype: distribution in the brain, development and functional significance
    • Ugrumov M.V. Non-dopaminergic neurons partly expressing dopaminergic phenotype: distribution in the brain, development and functional significance. J Chem Neuroanat 2009, 38:241-256.
    • (2009) J Chem Neuroanat , vol.38 , pp. 241-256
    • Ugrumov, M.V.1
  • 75
    • 0030687682 scopus 로고    scopus 로고
    • Do compensatory processes underlie the preclinical phase of neurodegenerative disease? Insights from an animal model of Parkinsonism
    • Zigmond M.J. Do compensatory processes underlie the preclinical phase of neurodegenerative disease? Insights from an animal model of Parkinsonism. Neurobiol Dis 1997, 4:247-253.
    • (1997) Neurobiol Dis , vol.4 , pp. 247-253
    • Zigmond, M.J.1
  • 76
    • 0025373167 scopus 로고
    • Compensations after lesions of central dopaminergic neurons: some clinical and basic implications
    • Zigmond M.J., Abercrombie E.D., Berger T.W., Grace A.A., Stricker E.M. Compensations after lesions of central dopaminergic neurons: some clinical and basic implications. Trends Neurosci 1990, 13:290-296.
    • (1990) Trends Neurosci , vol.13 , pp. 290-296
    • Zigmond, M.J.1    Abercrombie, E.D.2    Berger, T.W.3    Grace, A.A.4    Stricker, E.M.5


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