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Volumn 71, Issue 7, 2011, Pages 766-777

Androgen-induced PSA expression requires not only activation of AR but also endogenous IGF-I or IGF-I/PI3K/Akt signaling in human prostate cancer epithelial cells

Author keywords

catenin; Akt; AR; IGF I; Prostate cancer; PSA; R1881

Indexed keywords

ANDROGEN; BETA CATENIN; CYTOPLASMIC DEPHOSPHO BETA CATENIN; METRIBOLONE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTATE SPECIFIC ANTIGEN; PROTEIN KINASE B; SOMATOMEDIN C; UNCLASSIFIED DRUG;

EID: 79953679256     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21293     Document Type: Article
Times cited : (24)

References (41)
  • 1
    • 34447639257 scopus 로고    scopus 로고
    • Genetic analysis of androgen receptors in development and disease
    • Brinkmann AO, Trapman J. Genetic analysis of androgen receptors in development and disease. Adv Pharmacol 2000;47:317-341.
    • (2000) Adv Pharmacol , vol.47 , pp. 317-341
    • Brinkmann, A.O.1    Trapman, J.2
  • 2
    • 58249122148 scopus 로고    scopus 로고
    • Androgen receptor and growth factor signaling cross-talk in prostate cancer cells
    • Zhu ML, Kyprianou N. Androgen receptor and growth factor signaling cross-talk in prostate cancer cells. Endocr Relat Cancer 2008;15(4):841-849.
    • (2008) Endocr Relat Cancer , vol.15 , Issue.4 , pp. 841-849
    • Zhu, M.L.1    Kyprianou, N.2
  • 3
    • 0345392848 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-I, IGF-II and IGF type I receptor (IGFR-I) expression in prostatic cancer
    • Cardillo MR, Monti S, Di Silverio F, Gentile V, Sciarra F, Toscano V. Insulin-like growth factor (IGF)-I, IGF-II and IGF type I receptor (IGFR-I) expression in prostatic cancer. Anticancer Res 2003;23(5A):3825-3835.
    • (2003) Anticancer Res , vol.23 , Issue.5 A , pp. 3825-3835
    • Cardillo, M.R.1    Monti, S.2    Di Silverio, F.3    Gentile, V.4    Sciarra, F.5    Toscano, V.6
  • 5
    • 63249105294 scopus 로고    scopus 로고
    • Endocrine-immune-paracrine interactions in prostate cells as targeted by phytomedicines
    • Phila, PA
    • Gray NE, Liu X, Choi R, Blackman MR, Arnold JT. Endocrine-immune- paracrine interactions in prostate cells as targeted by phytomedicines. Cancer Prev Res (Phila, PA) 2009;2(2):134-142.
    • (2009) Cancer Prev Res , vol.2 , Issue.2 , pp. 134-142
    • Gray, N.E.1    Liu, X.2    Choi, R.3    Blackman, M.R.4    Arnold, J.T.5
  • 7
    • 13844262629 scopus 로고    scopus 로고
    • Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells
    • DOI 10.1152/ajpendo.00454.2004
    • Arnold JT, Le H, McFann KK, Blackman MR. Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells. Am J Physiol Endocrinol Metab 2005;288(3):E573-E584. (Pubitemid 40250553)
    • (2005) American Journal of Physiology - Endocrinology and Metabolism , vol.288 , Issue.3
    • Arnold, J.T.1    Le, H.2    McFann, K.K.3    Blackman, M.R.4
  • 8
    • 34250860909 scopus 로고    scopus 로고
    • Identification of androgen response elements in the insulin-like growth factor I upstream promoter
    • DOI 10.1210/en.2006-1653
    • Wu Y, Zhao W, Zhao J, Pan J, Wu Q, Zhang Y, Bauman WA, Cardozo CP. Identification of androgen response elements in the insulin-like growth factor I upstream promoter. Endocrinology 2007;148(6):2984-2993. (Pubitemid 46984806)
    • (2007) Endocrinology , vol.148 , Issue.6 , pp. 2984-2993
    • Wu, Y.1    Zhao, W.2    Zhao, J.3    Pan, J.4    Wu, Q.5    Zhang, Y.6    Bauman, W.A.7    Cardozo, C.P.8
  • 9
    • 33646435242 scopus 로고    scopus 로고
    • DHT and testosterone, but not DHEA or E2, differentially modulate IGFI, IGFBP-2, and IGFBP-3 in human prostatic stromal cells
    • Le H, Arnold JT, McFann KK, Blackman MR. DHT and testosterone, but not DHEA or E2, differentially modulate IGFI, IGFBP-2, and IGFBP-3 in human prostatic stromal cells. Am J Physiol Endocrinol Metab 2006;290(5):E952-E960.
    • (2006) Am J Physiol Endocrinol Metab , vol.290 , Issue.5
    • Le, H.1    Arnold, J.T.2    McFann, K.K.3    Blackman, M.R.4
  • 10
    • 5644252461 scopus 로고    scopus 로고
    • Synergy between PI3K/Akt and Raf/MEK/ERK pathways in IGF-1R mediated cell cycle progression and prevention of apoptosis in hematopoietic cells
    • Shelton JG, Steelman LS, White ER, McCubrey JA. Synergy between PI3K/Akt and Raf/MEK/ERK pathways in IGF-1R mediated cell cycle progression and prevention of apoptosis in hematopoietic cells. Cell Cycle 2004;3(3):372-379. (Pubitemid 41359089)
    • (2004) Cell Cycle , vol.3 , Issue.3 , pp. 372-379
    • Shelton, J.G.1    Steelman, L.S.2    White, E.R.3    McCubrey, J.A.4
  • 11
    • 17844406634 scopus 로고    scopus 로고
    • Relationship between obesity and prostate cancer
    • Amling CL. Relationship between obesity and prostate cancer. Curr Opin Urol 2005;15(3):167-171. (Pubitemid 40586176)
    • (2005) Current Opinion in Urology , vol.15 , Issue.3 , pp. 167-171
    • Amling, C.L.1
  • 13
    • 0032559272 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor-I and prostate cancer risk: A prospective study
    • DOI 10.1126/science.279.5350.563
    • Chan JM, Stampfer MJ, Giovannucci E, Gann PH, Ma J, Wilkinson P, Hennekens CH, Pollak M. Plasma insulin-like growth factor-I and prostate cancer risk: A prospective study. Science 1998;279(5350):563-566. (Pubitemid 28067285)
    • (1998) Science , vol.279 , Issue.5350 , pp. 563-566
    • Chan, J.M.1    Stampfer, M.J.2    Giovannucci, E.3    Gann, P.H.4    Ma, J.5    Wilkinson, P.6    Hennekens, C.H.7    Pollak, M.8
  • 15
    • 0028113415 scopus 로고
    • Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
    • Culig Z, Hobisch A, Cronauer MV, Radmayr C, Trapman J, Hittmair A, Bartsch G, Klocker H. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res 1994;54(20):5474-5478.
    • (1994) Cancer Res , vol.54 , Issue.20 , pp. 5474-5478
    • Culig, Z.1    Hobisch, A.2    Cronauer, M.V.3    Radmayr, C.4    Trapman, J.5    Hittmair, A.6    Bartsch, G.7    Klocker, H.8
  • 16
    • 0037203497 scopus 로고    scopus 로고
    • Potential action of IGF-1 and EGF on androgen receptor nuclear transfer and transactivation in normal and cancer human prostate cell lines
    • DOI 10.1016/S0303-7207(02)00374-X, PII S030372070200374X
    • Orio F Jr, Terouanne B, Georget V, Lumbroso S, Avances C, Siatka C, Sultan C. Potential action of IGF-1 and EGF on androgen receptor nuclear transfer and transactivation in normal and cancer human prostate cell lines. Mol Cell Endocrinol 2002;198(1-2):105-114. (Pubitemid 36169940)
    • (2002) Molecular and Cellular Endocrinology , vol.198 , Issue.1-2 , pp. 105-114
    • Orio Jr., F.1    Terouanne, B.2    Georget, V.3    Lumbroso, S.4    Avances, C.5    Siatka, C.6    Sultan, C.7
  • 19
    • 41849127826 scopus 로고    scopus 로고
    • Lycopene inhibits IGF-I signal transduction and growth in normal prostate epithelial cells by decreasing DHT-modulated IGF-I production in co-cultured reactive stromal cells
    • DOI 10.1093/carcin/bgn011
    • Liu X, Allen JD, Arnold JT, Blackman MR. Lycopene inhibits IGF-I signal transduction and growth in normal prostate epithelial cells by decreasing DHT-modulated IGF-I production in co-cultured reactive stromal cells. Carcinogenesis 2008;29(4):816-823. (Pubitemid 351494170)
    • (2008) Carcinogenesis , vol.29 , Issue.4 , pp. 816-823
    • Liu, X.1    Allen, J.D.2    Arnold, J.T.3    Blackman, M.R.4
  • 21
    • 5044238220 scopus 로고    scopus 로고
    • Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells
    • DOI 10.1210/me.2003-0436
    • Masiello D, Chen SY, Xu Y, Verhoeven MC, Choi E, Hollenberg AN, Balk SP. Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells. Mol Endocrinol 2004;18(10):2388-2401. (Pubitemid 39335975)
    • (2004) Molecular Endocrinology , vol.18 , Issue.10 , pp. 2388-2401
    • Masiello, D.1    Chen, S.-Y.2    Xu, Y.3    Verhoeven, M.C.4    Choi, E.5    Hollenberg, A.N.6    Balk, S.P.7
  • 22
    • 0037129305 scopus 로고    scopus 로고
    • In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis
    • Chesire DR, Ewing CM, Gage WR, Isaacs WB. In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis. Oncogene 2002;21(17):2679-2694.
    • (2002) Oncogene , vol.21 , Issue.17 , pp. 2679-2694
    • Chesire, D.R.1    Ewing, C.M.2    Gage, W.R.3    Isaacs, W.B.4
  • 23
    • 13544253453 scopus 로고    scopus 로고
    • Beta-catenin is involved in insulin-like growth factor 1-mediated transactivation of the androgen receptor
    • DOI 10.1210/me.2004-0208
    • Verras M, Sun Z. Beta-catenin is involved in insulin-like growth factor 1-mediated transactivation of the androgen receptor. Mol Endocrinol 2005;19(2):391-398. (Pubitemid 40223463)
    • (2005) Molecular Endocrinology , vol.19 , Issue.2 , pp. 391-398
    • Verras, M.1    Sun, Z.2
  • 25
    • 27844516613 scopus 로고    scopus 로고
    • Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins
    • Liu X, Rubin JS, Kimmel AR. Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins. Curr Biol 2005;15(22):1989-1997.
    • (2005) Curr Biol , vol.15 , Issue.22 , pp. 1989-1997
    • Liu, X.1    Rubin, J.S.2    Kimmel, A.R.3
  • 26
    • 77950258094 scopus 로고    scopus 로고
    • Dehydroepiandrosterone administration or Galpha q overexpression induces beta-catenin/ T-Cell factor signaling and growth via increasing association of estrogen receptor-beta/Dishevelled2 in androgen-independent prostate cancer cells
    • Liu X, Arnold JT, Blackman MR. Dehydroepiandrosterone administration or Galpha q overexpression induces beta-catenin/ T-Cell factor signaling and growth via increasing association of estrogen receptor-beta/Dishevelled2 in androgen-independent prostate cancer cells. Endocrinology 2010;151(4):1428-1440.
    • (2010) Endocrinology , vol.151 , Issue.4 , pp. 1428-1440
    • Liu, X.1    Arnold, J.T.2    Blackman, M.R.3
  • 27
    • 0035843148 scopus 로고    scopus 로고
    • Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation
    • DOI 10.1038/sj.onc.1204064
    • Desbois-Mouthon C, Cadoret A, Blivet-Van Eggelpoel MJ, Bertrand F, Cherqui G, Perret C, Capeau J. Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation. Oncogene 2001;20(2):252-259. (Pubitemid 32150270)
    • (2001) Oncogene , vol.20 , Issue.2 , pp. 252-259
    • Desbois-Mouthon, C.1    Cadoret, A.2    Blivet-Van, E.M.-J.3    Bertrand, F.4    Cherqui, G.5    Perret, C.6    Capeau, J.7
  • 29
    • 15844426173 scopus 로고    scopus 로고
    • Role of stromal-epithelial interactions in hormonal responses
    • DOI 10.1679/aohc.67.417
    • Cunha GR, Cooke PS, Kurita T. Role of stromal-epithelial interactions in hormonal responses. Arch Histol Cytol 2004;67(5):417-434. (Pubitemid 40424552)
    • (2004) Archives of Histology and Cytology , vol.67 , Issue.5 , pp. 417-434
    • Cunha, G.R.1    Cooke, P.S.2    Kurita, T.3
  • 30
    • 0028037903 scopus 로고
    • Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate
    • Cunha GR. Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate. Cancer 1994;74 (3 Suppl):1030-1044. (Pubitemid 24231999)
    • (1994) Cancer , vol.74 , Issue.3 , pp. 1030-1044
    • Cunha, G.R.1
  • 31
    • 33847020869 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-I controls prostate fibromuscular development: IGF-I inhibition prevents both fibromuscular and glandular development in eugonadal mice
    • Kleinberg DL, Ruan W, Yee D, Kovacs KT, Vidal S. Insulin-like growth factor (IGF)-I controls prostate fibromuscular development: IGF-I inhibition prevents both fibromuscular and glandular development in eugonadal mice. Endocrinology 2007;148(3):1080-1088.
    • (2007) Endocrinology , vol.148 , Issue.3 , pp. 1080-1088
    • Kleinberg, D.L.1    Ruan, W.2    Yee, D.3    Kovacs, K.T.4    Vidal, S.5
  • 32
    • 0033306843 scopus 로고    scopus 로고
    • Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development
    • Ruan W, Powell-Braxton L, Kopchick JJ, Kleinberg DL. Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development. Endocrinology 1999;140(5):1984-1989. (Pubitemid 30639064)
    • (1999) Endocrinology , vol.140 , Issue.5 , pp. 1984-1989
    • Ruan, W.1    Powell-Braxton, L.2    Kopchick, J.J.3    Kleinberg, D.L.4
  • 33
    • 0026753517 scopus 로고
    • Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma
    • Cohen P, Graves HC, Peehl DM, Kamarei M, Giudice LC, Rosenfeld RG. Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma. J Clin Endocrinol Metab 1992;75(4):1046-1053.
    • (1992) J Clin Endocrinol Metab , vol.75 , Issue.4 , pp. 1046-1053
    • Cohen, P.1    Graves, H.C.2    Peehl, D.M.3    Kamarei, M.4    Giudice, L.C.5    Rosenfeld, R.G.6
  • 34
    • 0037036393 scopus 로고    scopus 로고
    • Liganded androgen receptor interaction with beta-catenin: Nuclear co-localization and modulation of transcriptional activity in neuronal cells
    • DOI 10.1074/jbc.M200545200
    • Pawlowski JE, Ertel JR, Allen MP, Xu M, Butler C, Wilson EM, Wierman ME. Liganded androgen receptor interaction with beta-catenin: Nuclear co-localization and modulation of transcriptional activity in neuronal cells. J Biol Chem 2002;277(23):20702-20710. (Pubitemid 34967374)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.23 , pp. 20702-20710
    • Pawlowski, J.E.1    Ertel, J.R.2    Allen, M.P.3    Xu, M.4    Butler, C.5    Wilson, E.M.6    Wierman, M.E.7
  • 35
    • 0037124062 scopus 로고    scopus 로고
    • The androgen receptor can promote beta-catenin nuclear translocation independently of adenomatous polyposis coli
    • DOI 10.1074/jbc.M200135200
    • Mulholland DJ, Cheng H, Reid K, Rennie PS, Nelson CC. The androgen receptor can promote beta-catenin nuclear translocation independently of adenomatous polyposis coli. J Biol Chem 2002;277(20):17933-17943. (Pubitemid 34967604)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.20 , pp. 17933-17943
    • Mulholland, D.J.1    Cheng, H.2    Reid, K.3    Rennie, P.S.4    Nelson, C.C.5
  • 36
    • 29344440814 scopus 로고    scopus 로고
    • Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: Nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors
    • DOI 10.1210/en.2004-1649
    • Singh R, Artaza JN, Taylor WE, Braga M, Yuan X, Gonzalez- Cadavid NF, Bhasin S. Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: Nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors. Endocrinology 2006;147(1):141-154. (Pubitemid 43004269)
    • (2006) Endocrinology , vol.147 , Issue.1 , pp. 141-154
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Braga, M.4    Yuan, X.5    Gonzalez-Cadavid, N.F.6    Bhasin, S.7
  • 37
    • 33845760880 scopus 로고    scopus 로고
    • Castration-induced epithelial cell death in human prostate tissue is related to locally reduced IGF-1 levels
    • DOI 10.1002/pros.20480
    • Ohlson N, Bergh A, Stattin P, Wikstrom P. Castration-induced epithelial cell death in human prostate tissue is related to locally reduced IGF-1 levels. Prostate 2007;67(1):32-40. (Pubitemid 46013465)
    • (2007) Prostate , vol.67 , Issue.1 , pp. 32-40
    • Ohlson, N.1    Bergh, A.2    Stattin, P.3    Wikstrom, P.4
  • 38
    • 0035392953 scopus 로고    scopus 로고
    • Conversion from a paracrine to an autocrine mechanism of androgen-stimulated growth during malignant transformation of prostatic epithelial cells
    • Gao J, Arnold JT, Isaacs JT. Conversion from a paracrine to an autocrine mechanism of androgen-stimulated growth during malignant transformation of prostatic epithelial cells. Cancer Res 2001;61(13):5038-5044. (Pubitemid 32681532)
    • (2001) Cancer Research , vol.61 , Issue.13 , pp. 5038-5044
    • Gao, J.1    Arnold, J.T.2    Isaacs, J.T.3
  • 39
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
    • Kulik G, Klippel A, Weber MJ. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol Cell Biol 1997;17(3):1595-1606. (Pubitemid 27097389)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.3 , pp. 1595-1606
    • Kulik, G.1    Klippel, A.2    Weber, M.J.3
  • 40
    • 33846702027 scopus 로고    scopus 로고
    • Stromal-epithelial cell interactions and androgen receptor-coregulator recruitment is altered in the tissue microenvironment of prostate cancer
    • DOI 10.1158/0008-5472.CAN-06-1478
    • Cano P, Godoy A, Escamilla R, Dhir R, Onate SA. Stromal- epithelial cell interactions and androgen receptor-coregulator recruitment is altered in the tissue microenvironment of prostate cancer. Cancer Res 2007;67(2):511-519. (Pubitemid 46192187)
    • (2007) Cancer Research , vol.67 , Issue.2 , pp. 511-519
    • Cano, P.1    Godoy, A.2    Escamilla, R.3    Dhir, R.4    Onate, S.A.5
  • 41
    • 38549088816 scopus 로고    scopus 로고
    • Regulation of proliferation and differentiation of prostatic stromal cells by oestradiol through prostatic epithelial cells in a paracrine manner
    • DOI 10.1111/j.1464-410X.2007.07340.x
    • Wu Q, Shi J, Chen L, Wang CY, Park I, Lee C, Zhang J. Regulation of proliferation and differentiation of prostatic stromal cells by oestradiol through prostatic epithelial cells in a paracrine manner. Br J Urol Int 2008;101(4):497-502. (Pubitemid 351160939)
    • (2008) BJU International , vol.101 , Issue.4 , pp. 497-502
    • Wu, Q.1    Shi, J.2    Chen, L.3    Wang, C.-Y.4    Park, I.5    Lee, C.6    Zhang, J.7


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