Optimization of culture conditions for the expansion of umbilical cord-derived mesenchymal stem or stromal cell-like cells using xeno-free culture conditions

Tissue Engineering - Part C: Methods

Volumn 17, Issue 4, 2011, Pages 485-493

  Hatlapatka, Tim ^a   Moretti, Pierre ^a   Lavrentieva, Antonina ^a   Hass, Ralf ^b   Marquardt, Nicole ^b   Jacobs, Roland ^b   Kasper, Cornelia ^a  

^a LEIBNIZ UNIVERSITY HANNOVER   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CELL DEATH; CELL PROLIFERATION; ESTERS; EXPANSION; HISTOLOGY; OPTIMIZATION; TISSUE;

APOPTOSIS; BONE MARROW; CARBOXYFLUORESCEIN; CELL NUMBER; COCULTURE; COLONY FORMING UNITS; CULTURE CONDITIONS; DENTAL PULP; HIGH QUALITY; HUMAN SERUM; IN-VITRO; OPTIMAL CONCENTRATION; OPTIMAL GROWTH; OPTIMIZED PROTOCOL; PERIPHERAL BLOOD MONONUCLEAR CELLS; REGENERATIVE MEDICINE; STROMAL CELLS; SUCCINIMIDYL ESTER; UMBILICAL CORD BLOOD; UMBILICAL CORDS;

CELL CULTURE;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CULTURE MEDIUM; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; HUMAN; IMMUNOMODULATION; IMMUNOPHENOTYPING; MESENCHYMAL STEM CELL; METHODOLOGY; SERUM; STROMA CELL; UMBILICAL CORD;

CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA; HUMANS; IMMUNOMODULATION; IMMUNOPHENOTYPING; MESENCHYMAL STEM CELLS; SERUM; STROMAL CELLS; UMBILICAL CORD;

EID: 79953669690     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2010.0406     Document Type: Article

References (37)

1. Choong, P.F., Mok, P.L., Cheong, S.K., Leong, C.F., and Then, K.Y. Generating neuron-like cells from BM-derived mesenchymal stromal cells in vitro. Cytotherapy 9, 170, 2007.
2. Pittenger, M.F., Mackay, A.M., Beck, S.C., Jaiswal, R.K., Douglas, R., Mosca, J.D., et al. Multilineage potential of adult human mesenchymal stem cells. Science 284, 143, 1999.
3. Saulnier, N., Lattanzi, W., Puglisi, M.A., Pani, G., Barba, M., Piscaglia, A.C., et al. Mesenchymal stromal cells multi-potency and plasticity: induction toward the hepatic lineage. Eur Rev Med Pharmacol Sci 13 Suppl 1, 71, 2009.
4. Xu, R., Jiang, X., Guo, Z., Chen, J., Zou, Y., Ke, Y., et al. Functional analysis of neuron-like cells differentiated from neural stem cells derived from bone marrow stroma cells in vitro. Cell Mol Neurobiol 28, 545, 2008.
5. Kode, J.A., Mukherjee, S., Joglekar, M.V., and Hardikar, A.A. Mesenchymal stem cells: immunobiology and role in immunomodulation and tissue regeneration. Cytotherapy 11, 377, 2009.
6. Le Blanc, K. Immunomodulatory effects of fetal and adult mesenchymal stem cells. Cytotherapy 5, 485, 2003.
7. Le Blanc, K., and Ringden, O. Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 11, 321, 2005.
8. Siegel, G., Schafer, R., and Dazzi, F. The immunosuppressive properties of mesenchymal stem cells. Transplantation 87, S45, 2009.
9. Caplan, A.I. Why are MSCs therapeutic? New data: new insight. J Pathol 217, 318, 2009.
10. Meirelles Lda, S., Fontes, A.M., Covas, D.T., and Caplan, A.I. Mechanisms involved in the therapeutic properties of mes-enchymal stem cells. Cytokine Growth Factor Rev 20, 419, 2009.
11. Friedenstein, A.J. Osteogenetic activity of transplanted transitional epithelium. Acta Anat (Basel) 45, 31, 1961.
12. Mueller, S.M., and Glowacki, J. Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges. J Cell Biochem 82, 583, 2001.
13. Nishida, S., Endo, N., Yamagiwa, H., Tanizawa, T., and Takahashi, H.E. Number of osteoprogenitor cells in human bone marrow markedly decreases after skeletal maturation. J Bone Miner Metab 17, 171, 1999.
14. Stenderup, K., Justesen, J., Clausen, C., and Kassem, M. Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells. Bone 33, 919, 2003.
15. Da Silva Meirelles, L., Chagastelles, P.C., and Nardi, N.B. Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci 119, 2204, 2006.
16. Marcus, A.J., and Woodbury, D. Fetal stem cells from extra-embryonic tissues: do not discard. J Cell Mol Med 12, 730, 2008.
17. Pappa, K.I., and Anagnou, N.P. Novel sources of fetal stem cells: where do they fit on the developmental continuum? Regen Med 4, 423, 2009.
18. Erices, A., Conget, P., and Minguell, J.J. Mesenchymal progenitor cells in human umbilical cord blood. Br J Haematol 109, 235, 2000.
19. Romanov, Y.A., Svintsitskaya, V.A., and Smirnov, V.N. Searching for alternative sources of postnatal human mes-enchymal stem cells: candidate MSC-like cells from umbilical cord. Stem Cells 21, 105, 2003.
20. Mitchell, K.E., Weiss, M.L., Mitchell, B.M., Martin, P., Davis, D., Morales, L., et al. Matrix cells from Wharton's jelly form neurons and glia. Stem Cells 21, 50, 2003.
21. Sarugaser, R., Lickorish, D., Baksh, D., Hosseini, M.M., and Davies, J.E. Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors. Stem Cells 23, 220, 2005.
22. Moretti, P., Hatlapatka, T., Marten, D., Lavrentieva, A., Majore, I., Hass, R., et al. Mesenchymal stromal cells derived from human umbilical cord tissues: primitive cells with potential for clinical and tissue engineering applications. Adv Biochem Eng Biotechnol 123, 29, 2010.
23. Yang, C.C., Shih, Y.H., Ko, M.H., Hsu, S.Y., Cheng, H., and Fu, Y.S. Transplantation of human umbilical mesenchymal stem cells from Wharton's jelly after complete transection of the rat spinal cord. PLoS ONE 3, e3336, 2008.
24. Weiss, M.L., Medicetty, S., Bledsoe, A.R., Rachakatla, R.S., Choi, M., Merchav, S., et al. Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease. Stem Cells 24, 781, 2006.
25. Liao, W., Xie, J., Zhong, J., Liu, Y., Du, L., Zhou, B., et al. Therapeutic effect of human umbilical cord multipotent mesenchymal stromal cells in a rat model of stroke. Transplantation 87, 350, 2009.
26. Koh, S.H., Kim, K.S., Choi, M.R., Jung, K.H., Park, K.S., Chai, Y.G., et al. Implantation of human umbilical cord-derived mesenchymal stem cells as a neuroprotective therapy for ischemic stroke in rats. Brain Res 1229, 233, 2008.
27. Ennis, J., Gotherstrom, C., Le Blanc, K., and Davies, J.E. In vitro immunologic properties of human umbilical cord perivascular cells. Cytotherapy 10, 174, 2008.
28. Weiss, M.L., Anderson, C., Medicetty, S., Seshareddy, K.B., Weiss, R.J., VanderWerff, I., et al. Immune properties of human umbilical cord Wharton's jelly-derived cells. Stem Cells 26, 2865, 2008.
29. Yoo, K.H., Jang, I.K., Lee, M.W., Kim, H.E., Yang, M.S., Eom, Y., et al. Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues. Cell Immunol 259, 150, 2009.
30. Majore, I., Moretti, P., Hass, R., and Kasper, C. Identification of subpopulations in mesenchymal stem cell-like cultures from human umbilical cord. Cell Commun Signal 7, 6, 2009.
31. Lavrentieva, A., Majore, I., Kasper, C., and Hass, R. Effects of hypoxic culture conditions on umbilical cord-derived human mesenchymal stem cells. Cell Commun Signal 8, 18, 2010.
32. Majore, I., Moretti, P., Stahl, F., Hass, R., and Kasper, C. Growth and differentiation properties of mesenchymal stromal cell populations derived from whole human umbilical cord. Stem Cell Rev 2010. DOI: 10.1007/s12015.010-9165-y
33. Hoogduijn, M.J., Popp, F., Verbeek, R., Masoodi, M., Nico-laou, A., Baan, C., et al. The immunomodulatory properties of mesenchymal stem cells and their use for immunother-apy. Int Immunopharmacol 10, 1496, 2010.
34. Yagi, H., Soto-Gutierrez, A., Parekkadan, B., Kitagawa, Y., Tompkins, R.G., Kobayashi, N., et al. Mesenchymal stem cells: mechanisms of immunomodulation and homing. Cell Transplant 19, 667, 2010.
35. Jiang, X.X., Zhang, Y., Liu, B., Zhang, S.X., Wu, Y., Yu, X.D., et al. Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Blood 105, 4120, 2005.
36. Sotiropoulou, P.A., Perez, S.A., Gritzapis, A.D., Baxevanis, C.N., and Papamichail, M. Interactions between human mesenchymal stem cells and natural killer cells. Stem Cells 24, 74, 2006.
37. Tse, W.T., Pendleton, J.D., Beyer, W.M., Egalka, M.C., and Guinan, E.C. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation 75, 389, 2003.