Mesenchymal stromal cells multipotency and plasticity: Induction toward the hepatic lineage

European Review for Medical and Pharmacological Sciences

Volumn 13, Issue SUPPL. 1, 2009, Pages 71-78

  Saulnier, Nathalie ^a   Lattanzi, W ^a   Puglisi, M A ^a   Pani, G ^a   Barba, M ^a   Piscaglia, A C ^a   Giachelia, M ^a   Alfieri, S ^a   Neri, G ^a   Gasbarrini, G ^a   Gasbarrini, A ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Adipose tissue; Amniotic fluid; Autologous MSC based therapy; Bone marrow; Mesenchymal stromal cell; Mesodermal lineage

Indexed keywords

5' NUCLEOTIDASE; ALBUMIN; BETA1 INTEGRIN; CD133 ANTIGEN; CD45 ANTIGEN; CYTOCHROME P450 3A4; CYTOKERATIN 18; ENDOGLIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; STEM CELL FACTOR RECEPTOR; THY 1 ANTIGEN; TRYPTOPHAN 2,3 DIOXYGENASE; VASCULAR ENDOTHELIAL CADHERIN;

ADIPOSE TISSUE CELL; ADULT; AMNIOTIC FLUID CELL; ARTICLE; BIPOLAR SPINDLE SHAPED CELL; BONE MARROW; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL EXPANSION; CELL GROWTH; CELL ISOLATION; CELL KINETICS; CELL LINEAGE; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; CELL TYPE; CYTOMETRY; FETUS; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPHENOTYPING; IN VITRO STUDY; LIVER DEVELOPMENT; MESENCHYMAL STROMAL CELL; MESODERM; MULTIPOTENT STEM CELL; NORMAL HUMAN; PLASTICITY; POLYMERASE CHAIN REACTION; SECOND TRIMESTER PREGNANCY; STROMA CELL; TISSUE SPECIFICITY;

ADIPOSE TISSUE; AMNIOTIC FLUID; ANTIGENS, DIFFERENTIATION; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; HEPATOCYTES; HUMANS; MESENCHYMAL STEM CELLS; MULTIPOTENT STEM CELLS; ORGAN SPECIFICITY; PREGNANCY;

EID: 65249105997     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. FRIEDENSTEIN AJ. Osteogenic activity of transplanted transitional epithelium. Acta Anat 1961; 45: 31-59.
2. PITTENGER MF, MACKAY AM, BECK SC, JAISWAL RK, DOUGLAS R, MOSCA JD, MOORMAN MA, SIMONETTI DW, CRAIG S, MARSHAK DR. Multilineage potential of adult human stem cells. Science 1999; 284: 143-147.
3. MINGWELL JJ, ERICES A, CONGET P. Mesenchymal stem cells. Exp Biol Med 2001; 226: 507-520.
4. SANCHEZ-RAMOS J, SONG S, CARDOZO-PELAEZ F, HAZZI C, STEDEFORD T, WILLING A, FREEMAN TB, SAPORTA S, JANSSEN W, PATEL N, COOPER DR, SANBERG PR. Adult bone marrow stromal cells differentiate into neural cells in vitro. Exp Neurol 2000; 164: 247-256.
5. THEISE ND, BADVE S, SAXENA R, HENEGARIU O, SELL S, CRAWFORD JM, KRAUSE DS. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 2000; 31: 235-240.
6. HORWTTZ EM, PROCKOP DJ, GORDON PL, KOO WW, FITZ-PATRICK LA, NEEL MD, MCCARVILLE ME, ORCHARD PJ, PYERITZ RE, BRENNER MK. Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta. Blood 2001; 97: 1227-1231.
7. LAZARUS HM, KOC ON, DEVINE SM, CURTIN P, MAZIARZ RT, HOLLAND HK, SHPALL EJ, MCCARTHY P, ATKINSON K, COOPER BW, GERSON SL, LAUGHLIN MJ, LOBERIZA FR JR, MOSELEY AB, BACIGALUPO A. Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients. Biol Blood Marrow Transplant 2005; 11: 389-398.
8. WILLIAMS JT, SOUTHERLAND SS, SOUZA J, CALCUTT AF, CARTLEDGE RG. Cells isolated from adult human skeletal muscle capable of differentiating into multiple mesodermal phenotypes. Am Surg 1999; 65: 22-26.
9. ZUK PA, ZHU M, MIZUNO H, HUANG J, FUTRELL JW, KATZ AJ, BENHAIM P, LORENZ HP, HEDRICK MH. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 2001; 7: 211-228.
10. TULI R, TULI S, NANDI S, WANG ML, ALEXANDER PG, HALEEM-SMITH H, HOZACK WJ, MANNER PA, DANIELSON KG, TUAN RS. Characterization of multipotential mesenchymal progenitor cells derived from human trabecular bone. Stem Cells 2003; 21: 681-693.
11. DE BARI C, DELL'ACCIO F, TYLZANOWSKI P, LUYTEN FP. Multipotent mesenchymal stem cells from adult human synovial membrane. Arthritis Rheum 2001; 44: 1928-1942.
12. BIEBACK K, KERN S, KLÜTER H, EICHLER H. Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood. Stem Cells 2004; 22: 625-634.
13. IN'T ANKER PS, SCHERJON SA, KLEUBURG-VAN DER KEUR C, NOORT WA, CLAAS FH, WILLEMZE R, FIBBE WE, KANHAI HH. Amniotic fluid as a novel source of mesenchymal stem cells for therapeutic transplantation. Blood 2003; 102: 1548-1549.
14. IN'T ANKER PS, SCHERJON SA, KLEUBURG-VAN DER KEUR C, DE GROOT-SWINGS GM, CLAAS FH, FIBBE WE, KANHAI HH. Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem Cells 2004; 22: 1338-1345.
15. HATTORI H, SATO M, MASUOKA K, ISHIHARA M, KIKUCHI T, MATSUI T, TAKASE B, ISHIZUKA T, KIKUCHI M, FUJIKAWA K, ISHIHARA M. Osteogenic potential of human adipose tissue-derived stromal cells as an alternative stem cell source. Cells Tissues Organs 2004; 178: 2-12.
16. RODRIGUEZ AM, ELABD C, DELTEIL F, ASTIER J, VERNOCHET C, SAINT-MARC P, GUESNET J, GUEZENNEC A, AMRI EZ, DANI C, AILHAUD G. Adipocyte differentiation of multipotent cells established from human adipose tissue. Bioch Biophys Res Com 2004; 315: 255-263.
17. KERN S, EICHLER H, STOEVE J, KLUTER H, BIEBACK K. Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 2006; 24: 1294-1301.
18. GUILLOT PV, GOTHERSTROM C, CHAN J, KURATA H, FISK NM. Human first-trimester fetal MSC express pluripotency markers and grow faster and have longer telomeres than adult MSC. Stem Cells 2007; 25: 646-654.
19. DE COPPI P, BARTSCH G JR, SIDDIQUI MM, XU T, SANTOS CC, PERIN L, MOSTOSLAVSKY G, SERRE AC, SNYDER EY, YOO JJ, FURTH ME, SOKER S, ATALA A. Isolation of amniotic stem cell lines with potential for therapy Nat Biotechnol 2007; 25: 100-106.
20. ROUBELAKIS MG, PAPPA KI, BITSIKA V, ZAGOURA D, VLAHOU A, PAPADAKI HA, ANTSAKLIS A, ANAGNOU NP. Molecular and proteomic characterization of human mesenchymal stem cells derived from amniotic fluid: Comparison to bone marrow mesenchymal stem cells. Stem Cells Dev 2007; 16: 931-952.
21. TSAI MS, LEE JL, CHANG YJ, HWANG SM. Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol. Hum Reprod 2004; 19: 1450-1456.
22. LE BLANC K, RASMUSSON I, SUNDBERG B, GÖTHERSTRÖM C, HASSAN M, UZUNEL M, RINGDÉN O. Treatment of severe graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004; 11: 389-398.
23. YIN AH, MIRAGLIA S, ZANJANI ED, ALMEIDA-PORADA G, OGAWA M, LEARY AG, OLWEUS J, KEARNEY J, BUCK DW. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 1997; 90: 5002-5012.
24. UCHIDA N, BUCK DW, HE D, REITSMA MJ, MASEK M, PHAN TV, TSUKAMOTO AS, GAGE FH, WEISSMAN IL. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci USA 2000; 97: 14720-14725.
25. PRUSA AR, MARTON E, ROSNER M, BETTELHEIM D, LUBEC G, POLLACK A, BERNASCHEK G, HENGSTSCHLÄGER M. Neurogenic cells in human amniotic fluid. Am J Obstet Gynecol 2004; 191: 309-314.
26. PORADA CD, ZANJANI ED, ALMEIDA-PORAD G. Adult mesenchymal stem cells: A pluripotent population with multiple applications. Curr Stem Cell Res Ther 2006; 1: 365-369.
27. DE GEMMIS P, LAPUCCI C, BERTELLI M, TOGNETTO A, FANIN E, VETTOR R, PAGANO C, PANDOLFO M, FABBRI A. A real-time PCR approach to evaluate adipogenic potential of amniotic fluid-derived human mesenchymal stem cells. Stem Cells Dev 2006; 15: 719-728.
28. SEO MJ, SUH SY, BAE YC, YUNG JS. Differentiation of human adipose stromal cells into hepatic lineage in vitro and in vivo. Biochem Biophys Res Commun 2005; 328: 258-264.
29. WESTGREN M. In utero stem cell transplantation. Semin Reprod Med 2006; 24: 348-357.