Potent innate immune response to pathogenic Leptospira in human whole blood

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Goris, Marga G A ^a   Wagenaar, Jiri F P ^b   Hartskeerl, Rudy A ^a   van Gorp, Eric C M ^b,e   Schuller, Simone ^c   Monahan, Avril M ^c   Nally, Jarlath E ^c   van der Poll, Tom ^d   van't Veer, Cornelis ^d  

^a ROYAL TROPICAL INSTITUTE   (Netherlands)

^b SLOTERVAART HOSPITAL   (Netherlands)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

^e ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; PROTEIN LIGA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; UNCLASSIFIED DRUG; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CELL; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; BLOOD; CELL STIMULATION; CELL TYPE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GUINEA PIG; HEAT TREATMENT; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; INNATE IMMUNITY; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; MALE; MONOCYTE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; SENSITIVITY ANALYSIS; SEROTYPE; ANIMAL; CELL LINE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; LEPTOSPIRA; METABOLISM; MONONUCLEAR CELL; PATHOGENICITY; VIRULENCE;

CAVIA; LEPTOSPIRA;

ANIMALS; CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GUINEA PIGS; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-6; LEPTOSPIRA; LEUKOCYTES, MONONUCLEAR; TUMOR NECROSIS FACTOR-ALPHA; VIRULENCE;

EID: 79953644719     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018279     Document Type: Article

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