Long pentraxin PTX3 is associated with mortality and disease severity in severe Leptospirosis

Journal of Infection

Volumn 58, Issue 6, 2009, Pages 425-432

  Wagenaar, Jiri F P ^a   Goris, Marga G A ^b   Gasem, M Hussein ^c   Isbandrio, Bambang ^d   Moalli, Federica ^e   Mantovani, Alberto ^e,f   Boer, Kimberly R ^b   Hartskeerl, Rudy A ^b   Garlanda, Cecilia ^e   van Gorp, Eric C M ^a  

^a SLOTERVAART HOSPITAL   (Netherlands)

^b ROYAL TROPICAL INSTITUTE   (Netherlands)

^c DIPONEGORO UNIVERSITY   (Indonesia)

^d Faculty of Medicine   (Indonesia)

^e HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^f UNIVERSITY OF MILAN   (Italy)

Author keywords

Inflammation; Innate immunity; Leptospira; Leptospirosis; PTX3 protein; Sepsis

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; PENTRAXIN 3;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENDEMIC DISEASE; FEMALE; FOLLOW UP; HUMAN; INDONESIA; LABORATORY TEST; LEPTOSPIROSIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBSERVATIONAL STUDY; PATIENT MONITORING; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL;

ADULT; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; FEMALE; HUMANS; INDONESIA; INTERLEUKIN-6; INTERLEUKIN-8; LEPTOSPIROSIS; MALE; MIDDLE AGED; ODDS RATIO; PREDICTIVE VALUE OF TESTS; PROGNOSIS; ROC CURVE; SEPSIS; SERUM AMYLOID P-COMPONENT; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC;

EID: 65649148267     PISSN: 01634453     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinf.2009.04.004     Document Type: Article

References (30)

1. Vinetz J.M. Leptospirosis. Curr Opin Infect Dis 14 5 (2001 Oct) 527-538
2. Cinco M., Vecile E., Murgia R., Dobrina P., and Dobrina A. Leptospira interrogans and Leptospira peptidoglycans induce the release of tumor necrosis factor alpha from human monocytes. FEMS Microbiol Lett 138 2-3 (1996 May 1) 211-214
3. Fost de M., Hartskeerl R.A., Groenendijk M.R., and Poll v.d.T. Interleukin 12 in part regulates gamma interferon release in human whole blood stimulated with Leptospira interrogans. Clin Diagn Lab Immunol 10 2 (2003 Mar) 332-335
4. Chierakul W., Fost de M., Suputtamongkol Y., Limpaiboon R., Dondorp A., White N.J., et al. Differential expression of interferon-gamma and interferon-gamma-inducing cytokines in Thai patients with scrub typhus or leptospirosis. Clin Immunol 113 2 (2004 Nov) 140-144
5. Tajiki H., and Salomao R. Association of plasma levels of tumor necrosis factor alpha with severity of disease and mortality among patients with leptospirosis. Clin Infect Dis 23 5 (1996 Nov) 1177-1178
6. Mairuhu A.T., Peri G., Setiati T.E., Hack C.E., Koraka P., Soemantri A., et al. Elevated plasma levels of the long pentraxin, pentraxin 3, in severe dengue virus infections. J Med Virol 76 4 (2005 Aug) 547-552
7. Muller B., Peri G., Doni A., Torri V., Landmann R., Bottazzi B., et al. Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients. Crit Care Med 29 7 (2001 Jul) 1404-1407
8. Bevelacqua V., Libra M., Mazzarino M.C., Gangemi P., Nicotra G., Curatolo S., et al. Long pentraxin 3: a marker of inflammation in untreated psoriatic patients. Int J Mol Med 18 3 (2006 Sep) 415-423
9. Inoue K., Sugiyama A., Reid P.C., Ito Y., Miyauchi K., Mukai S., et al. Establishment of a high sensitivity plasma assay for human pentraxin 3 as a marker for unstable angina pectoris. Arterioscler Thromb Vasc Biol 27 1 (2007 Jan) 161-167
10. Latini R., Maggioni A.P., Peri G., Gonzini L., Lucci D., Mocarelli P., et al. Prognostic significance of the long pentraxin PTX3 in acute myocardial infarction. Circulation 110 16 (2004 Oct 19) 2349-2354
11. Suzuki S., Takeishi Y., Niizeki T., Koyama Y., Kitahara T., Sasaki T., et al. Pentraxin 3, a new marker for vascular inflammation, predicts adverse clinical outcomes in patients with heart failure. Am Heart J 155 1 (2008 Jan) 75-81
12. Garlanda C., Bottazzi B., Bastone A., and Mantovani A. Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility. Annu Rev Immunol 23 (2005) 337-366
13. Alles V.V., Bottazzi B., Peri G., Golay J., Introna M., and Mantovani A. Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes. Blood 84 10 (1994 Nov 15) 3483-3493
14. Breviario F., d'Aniello E.M., Golay J., Peri G., Bottazzi B., Bairoch A., et al. Interleukin-1-inducible genes in endothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component. J Biol Chem 267 31 (1992 Nov 5) 22190-22197
15. Doni A., Michela M., Bottazzi B., Peri G., Valentino S., Polentarutti N., et al. Regulation of PTX3, a key component of humoral innate immunity in human dendritic cells: stimulation by IL-10 and inhibition by IFN-gamma. J Leukoc Biol 79 4 (2006 Apr) 797-802
16. Goodman A.R., Levy D.E., Reis L.F., and Vilcek J. Differential regulation of TSG-14 expression in murine fibroblasts and peritoneal macrophages. J Leukoc Biol 67 3 (2000 Mar) 387-395
17. Han B., Mura M., Andrade C.F., Okutani D., Lodyga M., dos Santos C.C., et al. TNF alpha-induced long pentraxin PTX3 expression in human lung epithelial cells via JNK. J Immunol 175 12 (2005 Dec 15) 8303-8311
18. Lee G.W., Goodman A.R., Lee T.H., and Vilcek J. Relationship of TSG-14 protein to the pentraxin family of major acute phase proteins. J Immunol 153 8 (1994 Oct 15) 3700-3707
19. Luchetti M.M., Sambo P., Majlingova P., Svegliati B.S., Peri G., Paroncini P., et al. Scleroderma fibroblasts constitutively express the long pentraxin PTX3. Clin Exp Rheumatol 22 3 Suppl. 33 (2004 Jan) S66-S72
20. Nauta A.J., de Haij S., Bottazzi B., Mantovani A., Borrias M.C., Aten J., et al. Human renal epithelial cells produce the long pentraxin PTX3. Kidney Int 67 2 (2005 Feb) 543-553
21. He X., Han B., and Liu M. Long pentraxin 3 in pulmonary infection and acute lung injury. Am J Physiol Lung Cell Mol Physiol 292 5 (2007 May) L1039-L1049
22. Bottazzi B., Garlanda C., Salvatori G., Jeannin P., Manfredi A., and Mantovani A. Pentraxins as a key component of innate immunity. Curr Opin Immunol 18 1 (2006 Feb) 10-15
23. American College of Chest Physicians/Society of Critical Care Medicine. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20 6 (1992 Jun) 864-874
24. Levett P.N. Leptospirosis. Clin Microbiol Rev 14 2 (2001 Apr) 296-326
25. Ko A.I., Galvao R.M., Ribeiro Dourado C.M., Johnson Jr. W.D., and Riley L.W. Urban epidemic of severe leptospirosis in Brazil. Salvador Leptospirosis Study Group. Lancet 354 9181 (1999 Sep 4) 820-825
26. Calandra T., Gerain J., Heumann D., Baumgartner J.D., and Glauser M.P. High circulating levels of interleukin-6 in patients with septic shock: evolution during sepsis, prognostic value, and interplay with other cytokines. The Swiss-Dutch J5 Immunoglobulin Study Group. Am J Med 91 1 (1991 Jul) 23-29
27. Casey L.C., Balk R.A., and Bone R.C. Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med 119 8 (1993 Oct 15) 771-778
28. Pinsky M.R., Vincent J.L., Deviere J., Alegre M., Kahn R.J., and Dupont E. Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality. Chest 103 2 (1993 Feb) 565-575
29. Angus D.C., and Wax R.S. Epidemiology of sepsis: an update. Crit Care Med 29 7 Suppl. (2001 Jul) S109-S116
30. Song M., and Kellum J.A. Interleukin-6. Crit Care Med 33 12 Suppl. (2005 Dec) S463-S465