Adverse effects of exposure to low doses of chlorpyrifos in lactating rats

Toxicology and Industrial Health

Volumn 27, Issue 3, 2011, Pages 213-224

  Mansour, Sameeh A ^a   Mossa, Abdel Tawab H ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Chlorpyrifos; lactation rats; lipid peroxidation; liver and kidneys dysfunction; oxidative damage

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ASPARTATE AMINOTRANSFERASE; CHLORPYRIFOS; CHOLINESTERASE; CREATININE; GAMMA GLUTAMYLTRANSFERASE; GLOBULIN; GLUTATHIONE TRANSFERASE; LACTATE DEHYDROGENASE; PROTEIN; SUPEROXIDE DISMUTASE; URIC ACID;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CHOLINESTERASE BLOOD LEVEL; CREATININE BLOOD LEVEL; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HISTOPATHOLOGY; KIDNEY DYSFUNCTION; KIDNEY MASS; LACTATE DEHYDROGENASE BLOOD LEVEL; LACTATION; LIPID PEROXIDATION; LIVER DYSFUNCTION; LIVER HISTOLOGY; LIVER WEIGHT; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; RAT; URIC ACID BLOOD LEVEL;

ADMINISTRATION, ORAL; ANIMALS; BLOOD PROTEINS; BODY WEIGHT; CHLORPYRIFOS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUTATHIONE TRANSFERASE; INSECTICIDES; KIDNEY; LACTATION; LIPID PEROXIDATION; LIVER; LIVER FUNCTION TESTS; MALE; ORGAN SIZE; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; URIC ACID;

RATTUS;

EID: 79953330549     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/0748233710384054     Document Type: Article

References (75)

1. Abdollahi M., Ranjbar A., Shadnia S., Nikfar S., and Rezaie A. (2004) Pesticides and oxidative stress: a review. Medical Science Monitor, 10(6): RA141-RA147.
2. Adolph L. (1979) Diagnostische bedeutung der cholinesterasebestimmung im menschlichen serum. Med Wschr, 121: 1527-1530.
3. Akhgari M., Abdollahi M., Kebryaeezadeh A., Hosseini R., and Sabzevari O. (2003) Biochemical evidence for free radical induced lipid peroxidation as a mechanism for subchronic toxicity of malathion in blood and liver of rats. Human and Experimental Toxicology, 22: 205-211.
4. Ambali S., Akanbi D., Igbokwe N., and Shittu M. (2007) Evaluation of subchronic chlorpyrifos poisoning on hematological and serum biochemical changes in mice and protective effects of vitamin C. Toxicology Sciences, 32: 111-120.
5. Anderson HA, Wolff MS (2000) Environmental contaminations in human milk. Journal of Exposure Analysis and Environmental Epidemiology, 10: 755-760.
6. Bachowski S., Xu Y., Stevenson DE, Walborg EF, and Klaunig JE (1997) Role of oxidative stress in the mechanism of dieldrin’s heptotoxicity. Annals of Clinical Laboratory Science, 27: 196-209.
7. Bagchi D., Bagchi M., Hassoun EA, and Stohs SJ (1995) In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology, 104: 129-140.
8. Banerjee BD, Seth V., Bhattacharya A., Pasha ST, and Chakraborty AK (1999) Biochemical effects of pesticides on lipid peroxidation and free radicals scavengers. Toxicology Letter, 107: 33-47.
9. Barham D., Trinder P. (1972) An improved colour reagent for the determination of blood glucose by the oxidase system. Analyst, 97: 142-145.
10. Bartels H., Böhmer M., and Heierli C. (1972) Serum creatinine determination without protein precipitation. Clinica Chimica Acta, 37: 193-197.
11. Berkowitz GS, Wetmur JG, Birman-Deych E., Obel J., Lapinski RH, Godbold JH, et al. (2004). In utero pesticide exposure, maternal paraoxonase activity, and head circumference. Environmental Health Perspectives, 112(3): 388-391.
12. Brown SS, Kalow W., Pilz W., Whittaker M., and Woronick CL (1981) The plasma cholinesterases; a new perspective. Advances in Clinical Chemistry, 22: 82-83.
13. Bulusu S., Chakravarty I. (1986) Sub-acute administration of organophosphorus pesticides and hepatic drug metabolizing enzyme and malnourished rats. Bulletin of Environmental Contamination and Toxicology, 36: 73-80.
14. Butte NF, Garza C., Stuff JE, Smith EO, and Nichols BO (1984) Effect of maternal diet and body composition on lactational performance. American Journal of Clinical Nutrition, 39: 296-306.
15. Caglar C., Kolankaya D. (2007) The effect of sub-acute and sub-chronic exposure of rats to the glyphosate-based herbicide Roundup. Environmental Toxicology and Pharmacology, 25: 57-62.
16. Collaborative Group on Hormonal Factors in Breast Cancer (2002) Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50302 women with breast cancer and 96973 without the disease. Lancet, 360: 187-195.
17. Conolly RB, Beck BD, and Goodman JI (1999) Stimulating research to improve the scientific basis of risk assessment. Toxicology Sciences, 49: 1-4.
18. Cook JC, Kaplan AM, Davis LG, and O’Connor JC (1997) Development of a Tier I screening battery for detecting endocrine-active compounds (EACs). Regulatory Toxicology Pharmacology, 26: 60-68.
19. Davis DL, Ahmed AK (1998) Exposures from indoor spraying of chlorpyrifos pose greater health risks to children than currently estimated. Environmental Health Perspectives, 106(6): 299-301.
20. de Boer WB, Segal A., Frost FA, and Sterrett GF (2000) Can CD34 discriminate between benign and malignant hepatocytic lesions in fine-needle aspirates and thin core biopsies? Cancer, 90: 273-278.
21. De Kanter R., De Jager MH, Draaisma AL, Jurva, JU, Olinga P., Meijer DK, et al. (2002) Drug-metabolizing activity of human and rat liver, lung, kidney and intestine slices. Xenobiotica, 32: 349-362.
22. Draper HH, Hadley M. (1990) Malondialdehyde determination as index of lipid peroxidation. Methods in Enzymology, 186: 421-431.
23. El Sakka S., Salem E., and Abdel R. (2002) In vitro hepatotoxicity of alachlor and its by-products. Journal of Applied Toxicology, 22: 31-35.
24. Ellman GL, Courtney KD, Andres KD, and Featherstone RM (1961) A new and rapid calorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology, 7: 88-95.
25. Eskenazi B., Harley K., Bradman A., Weltzien E., Jewell NP, Barr DB, et al. (2004) Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population. Environmental Health Perspectives, 112(10): 1116-1124.
26. Fishbeck KL, Rasmussen KM (1987) Effect of repeated cycles on maternal nutritional status, lactational performance and litter growth in ad libitum fed and chronically food. Journal of Nutrition, 117: 1967-1975.
27. Gallenberg LA, Vodicnik MJ (1989) Transfer of persistent chemicals in milk. Drug Metabolism Review, 21: 277-317.
28. Gill TS, Pande J., and Tewari H. (1990) Sublethal eects of an organophosphorus insecticide on certain metabolite levels in a freshwater fish, Puntius conchonius Hamilton. Pesticide Biochemistry and Physiology, 36: 290-299.
29. Gill TS, Pande J., Tewari H. (1991) Individual and combined toxicity of common pesticides to teleost Puntius conchonius Hamilton. Indian Journal of Experimental Biology, 29: 145-148.
30. Goel A., Dani V., and Dhawan DK (2005) Protective effects of zinc on lipid peroxidation, antioxidant enzymes and hepatic histoarchitecture in chlorpyrifos-induced toxicity. Chemico-Biological Interactions, 156: 131-140.
31. Goel A., Dani V., and Dhawan DK (2007) Zinc mediates normalization of hepatic drug metabolizing enzymes in chlorpyrifos-induced toxicity. Toxicology Letter, 169: 26-33.
32. Gornall AC, Bardawill CJ, and David MM (1949) Determination of serum protein by means of biuret reaction. Journal of Biological Chemistry, 177: 751-756.
33. Gurunathan S., Robson M., Freeman N., Buckley B., Roy A., Meyer R., et al. (1998) Accumulation of chlorpyrifos on residential surfaces and toys accessible to children. Environmental Health Perspectives, 106(1): 9-16.
34. Habig WH, Pabst MJ, and Jakoby WB (1974) Glutathione S-transferases, the first enzymatic step in mercapturic acid formation. Journal of Biological Chemistry, 249: 7130-7139.
35. Halliwell B. (1996) Antioxidants in human health and disease. Annual Review Nutrition, 16: 33-50.
36. Halliwell B., and Gutteridge JMC (1999) Free Radicals in Biology and Medicine. 3rd ed. New York : Oxford University Press.
37. Hayes D., Pulford D. (1995) The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Critical Reviews in Biochemistry and Molecular Biology, 30: 445-600.
38. Interagency Staff Group on Carcinogens (1986) Chemical carcinogens: a review of the science and its associated principles. Environmental Health Perspectives, 67: 201-282.
39. Kamataki T., Neal RA (1976) Metabolism of diethyl p-nitrophenyl phosphorothionate (parathion) by a reconstituted mixed-function oxidase enzyme system: studies of the covalent binding of the sulfur atom. Molecular Pharmacology, 12: 933-944.
40. Kerem M., Bedirli N., Gurbuz N., Ekincl O., Bedirli A., Akkaya T., et al. (2007) Effects of acute fenthion toxicity on liver and kidney function and histology in rats. Turkish Journal of Medical Sciences, 37: 281-288.
41. Khan SM, Sobti RC, and Kataria L. (2005) Pesticide-induced alteration in mice hepato-oxidative status and protective effects of black tea extract. Clinica Chimica Acta, 358: 131-138.
42. Kramer MS, Kakuma R. (2002) Optimal duration of exclusive breastfeeding. Cochrane Database of Systematic Reviews; (7): CD003517.
43. Kuester RK, Waalkes MP, Goering PL, Fisher BL, McCuskey RS, and Sipes IG (2002) Differential hepatotoxicity induced by cadmium in Fischer 344 and Sprague-Dawley rats. Toxicology Sciences, 65: 151-159.
44. Mahboob M., Siddiqui MK (2001) Alterations in hepatic detoxifying enzymes induced by neworganophosphorus insecticides following subchronic exposure in rats. Journal of Applied Toxicology, 21: 501-505.
45. Mansour SA, Heikal TM, Mossa AH, and Refa A. (2008) Toxic effects of five insecticides and their mixture on male albino rats. Journal of Egyptian Society of Toxicology. 39: 85-94.
46. Mansour SA, Mossa AH (2005) Comparative effects of some insecticides as technical and formulated on male albino rats. Journal of Egyptian Society of Toxicology, 32: 41-54.
47. Mansour SA, Mossa AH (2009) Lipid peroxidation and oxidative stress in rat erythrocytes induced by chlorpyrifos and the protective effect of zinc. Pesticide Biochemistry and Physiology, 93: 34-39.
48. Mansour SA, Mossa AH. (2010a) Oxidative damage, biochemical and histopathological alterations in rats exposed to chlorpyrifos and the antioxidant role of zinc. Pesticide Biochemistry and Physiology, 96: 14-23.
49. Mansour SA, Mossa AH (2010b) Adverse effects of lactational exposure to chlorpyrifos in suckling rats. Human and Experimental Toxicology, 92(2): 77-92.
50. Marty MS, Domoradzki JY, Hansen SC, Timchalk C., Bartels MJ, and Mattsson JL (2007) The effect of route, vehicle, and divided doses on the pharmacokinetics of chlorpyrifos and its metabolite trichloropyridinol in neonatal Sprague-dawley rats. Toxicology Science, 100: 360-373.
51. Mattsson JL, Maurissen JP, Nolan RJ, and Brzak KA (2000) Lack of differential sensitivity to cholinesterase inhibition in fetuses and neonates compared to dams treated perinatally with chlorpyrifos. Toxicology Sciences, 53: 438-446.
52. Maurissen JPJ, Hoberman AM, Garman RH, and Hanley TR Jr (2000) Lack of selective developmental neuro-toxicity in rat pups from dams treated by gavage with chlorpyrifos. Toxicology Sciences, 57: 250-263.
53. McNamara JP, Hillers JK (1986) Adaptations in lipid metabolism of bovine adipose tissue in lactogenesis and lactation. Journal of Lipid Research, 27: 150-157.
54. Moss DW, and Henderson AR (1999) Enzymes. In: Burtis CA, Ashwood ER (eds.) Tietz Textbook of Clinical Chemistry. 2nd ed. Philadelphia: WB Saunders, 735-896.
55. Murray KF, Messner DJ, and Kowdley KV (2006) Mechanisms of hepatocyte detoxification. In: Johnson LR (ed.) Physiology of the Gastrointestinal Tract. Burlington: Elsevier Academic Press, 1483-1503.
56. National Research Council (NRC) (1996) Guide for the Care and Use of Laboratory Animals. Washington, DC: Academic Press.
57. Navarro CM, Montilla PM, Martin A., Jimenez J., and Utrilla PM (1993) Free radicals scavenger and antihepatotoxic activity of Rosmarinus. Plant Medicine, 59: 312-314.
58. Nolan RJ, Rick DL, Freshour NL, and Saunders JH (1984) Chlorpyrifos: pharmacokinetics in human volunteers. Toxicology and Applied Pharmacology, 73: 8-15.
59. Peraino C., Richards WL, and Stevens J. (1983) Multi-stage hepatocarcinogenesis. Environmental Health Perspectives, 56: 1-43.
60. Ranjbar A., Pasalar P., and Abdollahi M. (2002) Inducation of oxidative stress and acetylcholinesterase inhibition in organophosphorous pesticide manufacturing workers. Human and Experimental Toxicology, 21: 179-182.
61. Reitman S., Frankel S. (1957) A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. American Journal of Clinical Pathology, 28: 56-63.
62. Rosenblatt KA, Thomas DB (1993) WHO collaborative study on neoplasia and steroid contraceptives. International Journal of Epidemiology, 22: 192-197.
63. Salas JH, González MM, Noa M., Pérez NA, Díaz G., Gutiérrez R., et al. (2003) Organophosphorus pesticides in Mexico commercial pasteurized milk. Journal of Agriculture and Food Chemistry, 51: 4468-4471.
64. Sanghi R., Pillai MK, Jayalekshmi TR, and Nair A. (2003) Organochlorine and organophosphorus pesticides residues in breast milk from Bhopal, Madhya Pradesh, Indian. Human and Experimental Toxicology, 22: 73-76.
65. Sevanian A., Nordenbrand K., Kim E., Ernster L., and Hochstein P. (19900 Microsomal lipid peroxidation: the role of NADPH-cytochrome P450 reductase and cytochrome P450. Free Radical Biology and Medicine, 8: 145-152.
66. Shakoori AR, Butt U., Riffat R., Aziz F. (1994) Hematological and biochemical effects of danitol administered for two months on the blood and liver of rabbits. Zeitschrift fuer Angewandte Zoologie, 80: 165-180.
67. Szasz G. (1969) Kinetic photometric methods for serum gamma glutamyltranspeptidase. Clinical Chemistry, 15: 124-136.
68. Tietz NM (1995) Clinical Guide to Laboratory Tests. Philadelphia, PA: WB Saunders Company, 384-385.
69. Tomlin CDS (2005) The e-Pesticide Manual. 13th ed. CDROM version 3.1, The British Crop Protection Councill: Farnham, UK.
70. Wang X., Zhai W. (1988) Cellular and biochemical in bronchoalveolar lavage fluids of rats exposed to fenvalerate. Zhongguo Yaolixue YuDulixue Zoghi, 2: 271-276.
71. Westgard JO, Poquette MA (1972) Determination of serum albumin with the “SMA 12-60” by a bromcresol green dye-binding method. Clinical Chemistry, 18: 647-653.
72. Williams GM, Iatropoulos MJ (2002) Alteration of liver cell function and proliferation: differentiation between adaptation and toxicity. Toxicology Pathology, 30: 41-53.
73. Woolliams JA, Wiener G., Anderson PH, and McMurray CH (1983) Variation in the activities of glutathione peroxidase and superoxide dismutase and in the concentration of copper in the blood various breed crosses of sheep. Research in Veterinary Science, 34: 69-77.
74. Yamano T., Morita S. (1992) Hepatotoxicity of trichlorfon and dichlorvos in isolated rat hepatocytes. Toxicology, 76: 69-77.
75. Yano BL, Young JT, and Mattsson JL (2000) Lack of carcinogenicity of chlorpyrifos insecticide in a high-dose, 2-year dietary toxicity study in Fischer 344 rats. Toxicology Sciences, 53: 135-144.