메뉴 건너뛰기




Volumn 96, Issue 1, 2010, Pages 14-23

Oxidative damage, biochemical and histopathological alterations in rats exposed to chlorpyrifos and the antioxidant role of zinc

Author keywords

Biochemical and histopathological alterations; Chlorpyrifos; Gender; Liver and kidneys; Oxidative damage; Rats; Zinc

Indexed keywords

ANIMALIA; RATTUS;

EID: 72149117122     PISSN: 00483575     EISSN: 10959939     Source Type: Journal    
DOI: 10.1016/j.pestbp.2009.08.008     Document Type: Article
Times cited : (239)

References (70)
  • 1
    • 0002197595 scopus 로고    scopus 로고
    • Toxic effects of pesticides
    • Klaassen C.D. (Ed), McGraw-Hill, New York
    • Ecobichon D.J. Toxic effects of pesticides. In: Klaassen C.D. (Ed). Casarett and Doull's Toxicology (1996), McGraw-Hill, New York 643-698
    • (1996) Casarett and Doull's Toxicology , pp. 643-698
    • Ecobichon, D.J.1
  • 3
    • 0037619106 scopus 로고    scopus 로고
    • Biochemical evidence for free radical induced lipid peroxidation as a mechanism for subchronic toxicity of malathion in blood and liver of rats
    • Akhgari M., Abdollahi M., Kebryaeezadeh A., Hosseini R., and Sabzevari O. Biochemical evidence for free radical induced lipid peroxidation as a mechanism for subchronic toxicity of malathion in blood and liver of rats. Hum. Exp. Toxicol. 22 (2003) 205-211
    • (2003) Hum. Exp. Toxicol. , vol.22 , pp. 205-211
    • Akhgari, M.1    Abdollahi, M.2    Kebryaeezadeh, A.3    Hosseini, R.4    Sabzevari, O.5
  • 6
    • 33845791439 scopus 로고    scopus 로고
    • Reactive oxygen species in in vitro pesticide-induced neuronal cell (SH-SY5Y) cytotoxicity: role of NFkappaB and caspase-3
    • Jia Z., and Misra H.P. Reactive oxygen species in in vitro pesticide-induced neuronal cell (SH-SY5Y) cytotoxicity: role of NFkappaB and caspase-3. Free Radic. Biol. Med. 42 (2007) 288-298
    • (2007) Free Radic. Biol. Med. , vol.42 , pp. 288-298
    • Jia, Z.1    Misra, H.P.2
  • 7
    • 0037258896 scopus 로고    scopus 로고
    • Exposure to low doses of endosulfan and chlorpyrifos modifies endogenous antioxidants in tissue of rats
    • Bebe F.N., and Panemangalore N. Exposure to low doses of endosulfan and chlorpyrifos modifies endogenous antioxidants in tissue of rats. J. Environ. Sci. Health B 38 (2003) 349-363
    • (2003) J. Environ. Sci. Health B , vol.38 , pp. 349-363
    • Bebe, F.N.1    Panemangalore, N.2
  • 8
    • 0015427341 scopus 로고
    • Chronic toxicity of dursban and its metabolite 3,5,6-trichloro-2-pyridinol in chickens
    • Miyazaki S., and Hodgson G.C. Chronic toxicity of dursban and its metabolite 3,5,6-trichloro-2-pyridinol in chickens. Toxicol. Appl. Pharmacol. 23 (1972) 391-398
    • (1972) Toxicol. Appl. Pharmacol. , vol.23 , pp. 391-398
    • Miyazaki, S.1    Hodgson, G.C.2
  • 9
    • 0034091560 scopus 로고    scopus 로고
    • Protective effects of zinc in chlorpyrifos-induced hepatotoxicity: a biochemical and trace elemental study
    • Goel A., Chauhan D.P., and Dhawan D.K. Protective effects of zinc in chlorpyrifos-induced hepatotoxicity: a biochemical and trace elemental study. Biol. Trace Elem. Res. 74 (2000) 171-183
    • (2000) Biol. Trace Elem. Res. , vol.74 , pp. 171-183
    • Goel, A.1    Chauhan, D.P.2    Dhawan, D.K.3
  • 10
    • 26044483798 scopus 로고    scopus 로고
    • Protective effects of zinc on lipid peroxidation, antioxidant enzymes and hepatic histoarchitecture in chlorpyrifos-induced toxicity
    • Goel A., Dani V., and Dhawan D.K. Protective effects of zinc on lipid peroxidation, antioxidant enzymes and hepatic histoarchitecture in chlorpyrifos-induced toxicity. Chem. Biol. Interact. 156 (2005) 131-140
    • (2005) Chem. Biol. Interact. , vol.156 , pp. 131-140
    • Goel, A.1    Dani, V.2    Dhawan, D.K.3
  • 11
    • 0028001171 scopus 로고
    • Kinetic parameters of desulfuration and dearylation of parathion and chlorpyrifos by rat liver microsomes
    • Ma T., and Chambers J.E. Kinetic parameters of desulfuration and dearylation of parathion and chlorpyrifos by rat liver microsomes. Fundam. Chem. Toxicol. 32 (1994) 763-767
    • (1994) Fundam. Chem. Toxicol. , vol.32 , pp. 763-767
    • Ma, T.1    Chambers, J.E.2
  • 12
    • 0028273152 scopus 로고
    • Role of detoxification pathways in acute toxicity levels of phosphorothionate insecticides in the rat
    • Chambers J.E., Ma T., Boone J.S., and Chambers H.W. Role of detoxification pathways in acute toxicity levels of phosphorothionate insecticides in the rat. Life Sci. 54 (1994) 1357-1364
    • (1994) Life Sci. , vol.54 , pp. 1357-1364
    • Chambers, J.E.1    Ma, T.2    Boone, J.S.3    Chambers, H.W.4
  • 14
    • 0034099055 scopus 로고    scopus 로고
    • The antioxidant properties of zinc
    • Powell S.R. The antioxidant properties of zinc. J. Nutr. 130 (2000) 1447S-1454S
    • (2000) J. Nutr. , vol.130
    • Powell, S.R.1
  • 15
    • 0036804710 scopus 로고    scopus 로고
    • Free radicals, antioxidants, and nutrition
    • Fang Y.Z., Yang S., and Wu G. Free radicals, antioxidants, and nutrition. Nutrition 18 (2002) 872-879
    • (2002) Nutrition , vol.18 , pp. 872-879
    • Fang, Y.Z.1    Yang, S.2    Wu, G.3
  • 16
    • 0019860989 scopus 로고
    • A critical physiological role of zinc in the structure and function of biomembranes
    • Bettger W.J., and O'Dell B.L. A critical physiological role of zinc in the structure and function of biomembranes. Life Sci. 28 (1981) 1425-1438
    • (1981) Life Sci. , vol.28 , pp. 1425-1438
    • Bettger, W.J.1    O'Dell, B.L.2
  • 17
  • 18
    • 58149216649 scopus 로고    scopus 로고
    • Lipid peroxidation and oxidative stress in rat erythrocytes induced by chlorpyrifos and the protective effect of zinc
    • Mansour S.A., and Mossa A.H. Lipid peroxidation and oxidative stress in rat erythrocytes induced by chlorpyrifos and the protective effect of zinc. Pest. Biochem. Physiol. 93 (2009) 34-39
    • (2009) Pest. Biochem. Physiol. , vol.93 , pp. 34-39
    • Mansour, S.A.1    Mossa, A.H.2
  • 20
    • 33746018710 scopus 로고    scopus 로고
    • Protective effect of black tea extract on the levels of lipid peroxidation and antioxidant enzymes in liver of mice with pesticide induced liver injury
    • Khan S.M. Protective effect of black tea extract on the levels of lipid peroxidation and antioxidant enzymes in liver of mice with pesticide induced liver injury. Cell Biol. Funct. 24 (2006) 332-372
    • (2006) Cell Biol. Funct. , vol.24 , pp. 332-372
    • Khan, S.M.1
  • 21
    • 0003633755 scopus 로고    scopus 로고
    • NRC, National Research Council, Acad. Press, Washington, DC
    • NRC, Guide for the Care and Use of Laboratory Animals, National Research Council, Acad. Press, Washington, DC, 1996, p. 12.
    • (1996) Guide for the Care and Use of Laboratory Animals , pp. 12
  • 22
    • 39749171518 scopus 로고    scopus 로고
    • Comparative effects of some insecticides as technical and formulated on male albino rats
    • Mansour S.A., and Mossa A.H. Comparative effects of some insecticides as technical and formulated on male albino rats. J. Egypt. Soc. Toxicol. 32 (2005) 41-54
    • (2005) J. Egypt. Soc. Toxicol. , vol.32 , pp. 41-54
    • Mansour, S.A.1    Mossa, A.H.2
  • 23
    • 0020621878 scopus 로고
    • Variation in the activities of glutathione peroxidase and superoxide dismutase and in the concentration of copper in the blood various breed crosses of sheep
    • Woolliams J.A., Wiener G., Anderson P.H., and McMurray C.H. Variation in the activities of glutathione peroxidase and superoxide dismutase and in the concentration of copper in the blood various breed crosses of sheep. Res. Vet. Sci. 34 (1983) 69-77
    • (1983) Res. Vet. Sci. , vol.34 , pp. 69-77
    • Woolliams, J.A.1    Wiener, G.2    Anderson, P.H.3    McMurray, C.H.4
  • 24
    • 0016275313 scopus 로고
    • Glutathione S-transferases, the first enzymatic step in mercapturic acid formation
    • Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione S-transferases, the first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249 (1974) 7130-7139
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 25
    • 0025142672 scopus 로고
    • Malondialdehyde determination as index of lipid peroxidation
    • Draper H.H., and Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol. 186 (1990) 421-431
    • (1990) Methods Enzymol. , vol.186 , pp. 421-431
    • Draper, H.H.1    Hadley, M.2
  • 26
    • 66349129125 scopus 로고
    • A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases
    • Reitman S., and Frankel S. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am. J. Clin. Pathol. 28 (1957) 56-63
    • (1957) Am. J. Clin. Pathol. , vol.28 , pp. 56-63
    • Reitman, S.1    Frankel, S.2
  • 28
    • 0014467815 scopus 로고
    • Kinetic photometric method for serum gamma glutamyltranspeptidase
    • Szasz G. Kinetic photometric method for serum gamma glutamyltranspeptidase. Clin. Chem. 15 (1969) 124-136
    • (1969) Clin. Chem. , vol.15 , pp. 124-136
    • Szasz, G.1
  • 30
    • 0015373419 scopus 로고
    • Determination of serum albumin with the "SMA 12-60" by a bromcresol green dye-binding method
    • Westgard J.O., and Poquette M.A. Determination of serum albumin with the "SMA 12-60" by a bromcresol green dye-binding method. Clin. Chem. 18 (1972) 647-653
    • (1972) Clin. Chem. , vol.18 , pp. 647-653
    • Westgard, J.O.1    Poquette, M.A.2
  • 31
    • 29744466425 scopus 로고
    • Determination of serum protein by means of biuret reaction
    • Gornall A.C., Bardawill C.J., and David M.M. Determination of serum protein by means of biuret reaction. J. Biol. Chem. 177 (1949) 751-756
    • (1949) J. Biol. Chem. , vol.177 , pp. 751-756
    • Gornall, A.C.1    Bardawill, C.J.2    David, M.M.3
  • 32
    • 0015297282 scopus 로고
    • An improved colour reagent for the determination of blood glucose by the oxidase system
    • Barham D., and Trinder P. An improved colour reagent for the determination of blood glucose by the oxidase system. Analyst 97 (1972) 142-145
    • (1972) Analyst , vol.97 , pp. 142-145
    • Barham, D.1    Trinder, P.2
  • 33
    • 0015305121 scopus 로고
    • Serum creatinine determination without protein precipitation
    • Bartels H., Böhmer M., and Heierli C. Serum creatinine determination without protein precipitation. Clin. Chim. Acta 37 (1972) 193-197
    • (1972) Clin. Chim. Acta , vol.37 , pp. 193-197
    • Bartels, H.1    Böhmer, M.2    Heierli, C.3
  • 36
    • 0141992353 scopus 로고    scopus 로고
    • Liver
    • Haschek-Hock W.M., and Rousseaux C.G. (Eds), Academic Press, San Diego
    • Cattley R.C., and Popp J.A. Liver. In: Haschek-Hock W.M., and Rousseaux C.G. (Eds). Handbook of Toxicology Pathology. second ed. (2002), Academic Press, San Diego 187-225
    • (2002) Handbook of Toxicology Pathology. second ed. , pp. 187-225
    • Cattley, R.C.1    Popp, J.A.2
  • 37
    • 34249782834 scopus 로고    scopus 로고
    • Evaluation of subchronic chlorpyrifos poisoning on hematological and serum biochemical changes in mice and protective effects of vitamin c
    • Ambali S., Akanbi D., Igbokwe N., and Shittu M. Evaluation of subchronic chlorpyrifos poisoning on hematological and serum biochemical changes in mice and protective effects of vitamin c. J. Toxicol. Sci. 32 (2007) 111-120
    • (2007) J. Toxicol. Sci. , vol.32 , pp. 111-120
    • Ambali, S.1    Akanbi, D.2    Igbokwe, N.3    Shittu, M.4
  • 38
    • 0034782405 scopus 로고    scopus 로고
    • Zinc supplementation prevents liver injury in chlorpyrifos-treated rats
    • Goal A., and Dhawan D.K. Zinc supplementation prevents liver injury in chlorpyrifos-treated rats. Biol. Trace Elem. Res. 82 (2001) 185-200
    • (2001) Biol. Trace Elem. Res. , vol.82 , pp. 185-200
    • Goal, A.1    Dhawan, D.K.2
  • 39
    • 0037258896 scopus 로고    scopus 로고
    • Exposure to low doses of endosulfan and chlorpyrifos modifies endogenous antioxidants in tissues of rats
    • Bebe F.N., and Panemangalore M. Exposure to low doses of endosulfan and chlorpyrifos modifies endogenous antioxidants in tissues of rats. J. Environ. Sci. Health B 38 (2003) 349-363
    • (2003) J. Environ. Sci. Health B , vol.38 , pp. 349-363
    • Bebe, F.N.1    Panemangalore, M.2
  • 40
    • 0035997882 scopus 로고    scopus 로고
    • Induction of oxidative stress and acetylcholinesterase inhibition in organophosphorous pesticide manufacturing workers
    • Ranjbar A., Pasalar P., and Abdollahi M. Induction of oxidative stress and acetylcholinesterase inhibition in organophosphorous pesticide manufacturing workers. Hum. Exp. Toxicol. 21 (2002) 179-182
    • (2002) Hum. Exp. Toxicol. , vol.21 , pp. 179-182
    • Ranjbar, A.1    Pasalar, P.2    Abdollahi, M.3
  • 42
    • 0033558579 scopus 로고    scopus 로고
    • Antioxidant enzymes and their implications in pathophysiologic processes
    • Mates J.M., and Sanchez-Jimenez F. Antioxidant enzymes and their implications in pathophysiologic processes. Front. Biosci. 4 (1999) 334-345
    • (1999) Front. Biosci. , vol.4 , pp. 334-345
    • Mates, J.M.1    Sanchez-Jimenez, F.2
  • 43
    • 42149155984 scopus 로고    scopus 로고
    • Clinical, immunological, anti-inflammatory and antioxidant roles of zinc
    • Prasad A.S. Clinical, immunological, anti-inflammatory and antioxidant roles of zinc. Exp. Gerontol. 43 (2008) 370-377
    • (2008) Exp. Gerontol. , vol.43 , pp. 370-377
    • Prasad, A.S.1
  • 44
    • 0013359842 scopus 로고
    • Zinc and enzymes
    • Prasad A.S. (Ed), Plenum Press, New York
    • Prasad A.S. Zinc and enzymes. In: Prasad A.S. (Ed). Biochemistry of Zinc (1993), Plenum Press, New York 17-53
    • (1993) Biochemistry of Zinc , pp. 17-53
    • Prasad, A.S.1
  • 45
    • 0029561598 scopus 로고
    • The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
    • Hayes D., and Pulford D. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit. Rev. Biochem. Mol. Biol. 30 (1995) 445-600
    • (1995) Crit. Rev. Biochem. Mol. Biol. , vol.30 , pp. 445-600
    • Hayes, D.1    Pulford, D.2
  • 46
    • 0021066397 scopus 로고
    • Zinc effects on glutathione metabolism relationship to zinc-induced protection from alkylating agents
    • Seagrave J., Tobey R.A., and Hildebrand C.E. Zinc effects on glutathione metabolism relationship to zinc-induced protection from alkylating agents. Biochem. Pharmacol. 32 (1983) 3017-3021
    • (1983) Biochem. Pharmacol. , vol.32 , pp. 3017-3021
    • Seagrave, J.1    Tobey, R.A.2    Hildebrand, C.E.3
  • 47
    • 4444342654 scopus 로고    scopus 로고
    • Endosulfan-induced cardiotoxicity and free radical metabolism in rats: the protective effect of vitamin E
    • Kalender S., Kalender Y., Ogutcu A., Uzunhisarikli M., Durak D., and Anikgoz F. Endosulfan-induced cardiotoxicity and free radical metabolism in rats: the protective effect of vitamin E. Toxicology 202 (2004) 227-235
    • (2004) Toxicology , vol.202 , pp. 227-235
    • Kalender, S.1    Kalender, Y.2    Ogutcu, A.3    Uzunhisarikli, M.4    Durak, D.5    Anikgoz, F.6
  • 48
    • 0027408080 scopus 로고
    • Free radical as mediator of tissue injury and disease
    • Kehrer J.P. Free radical as mediator of tissue injury and disease. Crit. Rev. Toxicol. 23 (1993) 21-48
    • (1993) Crit. Rev. Toxicol. , vol.23 , pp. 21-48
    • Kehrer, J.P.1
  • 49
  • 50
    • 0035949809 scopus 로고    scopus 로고
    • Biotransformation of organophosphorus compounds
    • Jokanovic M. Biotransformation of organophosphorus compounds. Toxicology 166 (2001) 139-160
    • (2001) Toxicology , vol.166 , pp. 139-160
    • Jokanovic, M.1
  • 51
    • 33846796343 scopus 로고    scopus 로고
    • Zinc mediates normalization of hepatic drug metabolizing enzymes in chlorpyrifos-induced toxicity
    • Goel A., Dani V., and Dhawan D.K. Zinc mediates normalization of hepatic drug metabolizing enzymes in chlorpyrifos-induced toxicity. Toxicol. Lett. 169 (2007) 26-33
    • (2007) Toxicol. Lett. , vol.169 , pp. 26-33
    • Goel, A.1    Dani, V.2    Dhawan, D.K.3
  • 52
    • 0017194214 scopus 로고
    • Metabolism of diethyl p-nitrophenyl phosphorothionate (parathion) by a reconstituted mixed-function oxidase enzyme system: studies of the covalent binding of the sulfur atom
    • Kamataki T., and Neal R.A. Metabolism of diethyl p-nitrophenyl phosphorothionate (parathion) by a reconstituted mixed-function oxidase enzyme system: studies of the covalent binding of the sulfur atom. Mol. Pharmacol. 12 (1976) 933-944
    • (1976) Mol. Pharmacol. , vol.12 , pp. 933-944
    • Kamataki, T.1    Neal, R.A.2
  • 53
    • 0025217604 scopus 로고
    • Microsomal lipid peroxidation: the role of NADPH-cytochrome P450 reductase and cytochrome P450
    • Sevanian A., Nordenbrand K., Kim E., Ernster L., and Hochstein P. Microsomal lipid peroxidation: the role of NADPH-cytochrome P450 reductase and cytochrome P450. Free Radic. Biol. Med. 8 (1990) 145-152
    • (1990) Free Radic. Biol. Med. , vol.8 , pp. 145-152
    • Sevanian, A.1    Nordenbrand, K.2    Kim, E.3    Ernster, L.4    Hochstein, P.5
  • 54
    • 0018842735 scopus 로고
    • Enhanced lipid peroxidation in liver microsomes of zinc-deficient rats
    • Sullivan J.F., Jetton M.M., Hahn H.K., and Burch R.E. Enhanced lipid peroxidation in liver microsomes of zinc-deficient rats. Am. J. Clin. Nutr. 33 (1980) 51-56
    • (1980) Am. J. Clin. Nutr. , vol.33 , pp. 51-56
    • Sullivan, J.F.1    Jetton, M.M.2    Hahn, H.K.3    Burch, R.E.4
  • 55
    • 0035044396 scopus 로고    scopus 로고
    • In vivo changes in antioxidant systems and protective role of melatonin and a combination of vitamin C and vitamin E on oxidative damage in erythrocytes induced by chlorpyrifos-ethyl in rats
    • Gultekin F., Delibas N., Yasar S., and Kilinc I. In vivo changes in antioxidant systems and protective role of melatonin and a combination of vitamin C and vitamin E on oxidative damage in erythrocytes induced by chlorpyrifos-ethyl in rats. Arch. Toxicol. 75 (2001) 88-96
    • (2001) Arch. Toxicol. , vol.75 , pp. 88-96
    • Gultekin, F.1    Delibas, N.2    Yasar, S.3    Kilinc, I.4
  • 56
    • 0015415670 scopus 로고
    • Effect of zinc on lipid peroxidation in liver microsomes and mitochondria
    • Chvapil M., Ryan J.N., and Zukoski C.F. Effect of zinc on lipid peroxidation in liver microsomes and mitochondria. Proc. Soc. Exp. Biol. Med. 141 (1972) 150-153
    • (1972) Proc. Soc. Exp. Biol. Med. , vol.141 , pp. 150-153
    • Chvapil, M.1    Ryan, J.N.2    Zukoski, C.F.3
  • 57
    • 22044442997 scopus 로고    scopus 로고
    • Pesticide-induced alteration in mice hepato-oxidative status and protective effects of black tea extract
    • Khan S.M., Sobti R.C., and Kataria L. Pesticide-induced alteration in mice hepato-oxidative status and protective effects of black tea extract. Clin. Chim. Acta 358 (2005) 131-138
    • (2005) Clin. Chim. Acta , vol.358 , pp. 131-138
    • Khan, S.M.1    Sobti, R.C.2    Kataria, L.3
  • 59
    • 0023723410 scopus 로고
    • Cellular and biochemical in bronchoalveolar lavage fluids of rats exposed to fenvalerate
    • Wang X., and Zhai W. Cellular and biochemical in bronchoalveolar lavage fluids of rats exposed to fenvalerate. Zhongguo Yaolixue YuDulixue Zoghi 2 (1988) 271-276
    • (1988) Zhongguo Yaolixue YuDulixue Zoghi , vol.2 , pp. 271-276
    • Wang, X.1    Zhai, W.2
  • 60
    • 4644305395 scopus 로고    scopus 로고
    • Effects of vitamin E supplementation on oxidative stress in streptozotocin induced diabetic rats: investigation of liver and plasma
    • Seven A., Güzel S., Seymen O., Civelek S., Bolayirh M., Uncu M., and BurÇak G. Effects of vitamin E supplementation on oxidative stress in streptozotocin induced diabetic rats: investigation of liver and plasma. Yonsei Med. J. 45 (2004) 703-710
    • (2004) Yonsei Med. J. , vol.45 , pp. 703-710
    • Seven, A.1    Güzel, S.2    Seymen, O.3    Civelek, S.4    Bolayirh, M.5    Uncu, M.6    BurÇak, G.7
  • 61
    • 72149090441 scopus 로고    scopus 로고
    • Toxic effects of five insecticides and their mixture on male albino rats
    • Mansour S.A., Heikal T.M., Mossa A.H., and Refa A. Toxic effects of five insecticides and their mixture on male albino rats. J. Egypt. Soc. Toxicol. 39 (2008) 85-94
    • (2008) J. Egypt. Soc. Toxicol. , vol.39 , pp. 85-94
    • Mansour, S.A.1    Heikal, T.M.2    Mossa, A.H.3    Refa, A.4
  • 62
    • 0032536117 scopus 로고    scopus 로고
    • Rat brain acetylcholinesterase activity, developmental profile and maturational sensitivity to carbamate and organophosphorous inhibitors
    • Mortensen S.R., Hooper M.J., and Padilla S. Rat brain acetylcholinesterase activity, developmental profile and maturational sensitivity to carbamate and organophosphorous inhibitors. Toxicology 125 (1998) 9-13
    • (1998) Toxicology , vol.125 , pp. 9-13
    • Mortensen, S.R.1    Hooper, M.J.2    Padilla, S.3
  • 64
    • 0031713093 scopus 로고    scopus 로고
    • Inhibition of acetylcholinesterase and butyrylcholinesterase by chlorpyrifos oxon
    • Amitai G., Moorad D., Adani R., and Doctor B.P. Inhibition of acetylcholinesterase and butyrylcholinesterase by chlorpyrifos oxon. Biochem. Pharmacol. 56 (1998) 293-299
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 293-299
    • Amitai, G.1    Moorad, D.2    Adani, R.3    Doctor, B.P.4
  • 65
    • 34147102481 scopus 로고    scopus 로고
    • Biotransformation: a balance between bioactivation and detoxification
    • Williams P.L., James R.C., and Roberts S.M. (Eds), John Wiley & Sons, Inc.
    • Franklin M.R., and Yost G.S. Biotransformation: a balance between bioactivation and detoxification. In: Williams P.L., James R.C., and Roberts S.M. (Eds). Principles of Toxicology: Environmental and Industrial Applications (2000), John Wiley & Sons, Inc. 57-86
    • (2000) Principles of Toxicology: Environmental and Industrial Applications , pp. 57-86
    • Franklin, M.R.1    Yost, G.S.2
  • 66
    • 33646251808 scopus 로고    scopus 로고
    • Effects of dimethoate (O,O-dimethyl S-methyl carbamoyl methyl phosphorodithioate) and ethanol in antioxidant status of liver and kidney of experimental mice
    • Sivapiriya V., Jayanthisakthisekaran J., and Venkatraman S. Effects of dimethoate (O,O-dimethyl S-methyl carbamoyl methyl phosphorodithioate) and ethanol in antioxidant status of liver and kidney of experimental mice. Pest. Biochem. Physiol. 85 (2006) 115-121
    • (2006) Pest. Biochem. Physiol. , vol.85 , pp. 115-121
    • Sivapiriya, V.1    Jayanthisakthisekaran, J.2    Venkatraman, S.3
  • 67
    • 0015221086 scopus 로고
    • Clinical evaluation of kidney function
    • Kassirer J.P. Clinical evaluation of kidney function. N. Engl. J. Med. 285 (1971) 385-389
    • (1971) N. Engl. J. Med. , vol.285 , pp. 385-389
    • Kassirer, J.P.1
  • 69
    • 0017182265 scopus 로고
    • Inhibition of NADPH oxidation and related drug oxidation in liver microsomes by zinc
    • Chvapil M., Ludwig J.C., Sipes I.G., and Misiorowski R.L. Inhibition of NADPH oxidation and related drug oxidation in liver microsomes by zinc. Biochem. Pharmacol. 25 (1976) 1787-1791
    • (1976) Biochem. Pharmacol. , vol.25 , pp. 1787-1791
    • Chvapil, M.1    Ludwig, J.C.2    Sipes, I.G.3    Misiorowski, R.L.4
  • 70
    • 0018567627 scopus 로고
    • Protection of carbon tetrachloride-induced hepatotoxicity by zinc: role of metallothionein
    • Cagen S.Z., and Klaassen C.D. Protection of carbon tetrachloride-induced hepatotoxicity by zinc: role of metallothionein. Toxicol. Appl. Pharmacol. 51 (1979) 107-116
    • (1979) Toxicol. Appl. Pharmacol. , vol.51 , pp. 107-116
    • Cagen, S.Z.1    Klaassen, C.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.