Beta interferon suppresses the development of experimental cerebral malaria

Infection and Immunity

Volumn 79, Issue 4, 2011, Pages 1750-1758

  Morrell, Craig N ^a   Srivastava, Kalyan ^a   Swaim, AnneMarie ^b   Lee, M Teresa ^b   Chen, Jun ^c   Hooks, Chandrashakaharam Nagineni ^c   Detrick, Barbara ^b  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CHEMOKINE RECEPTOR CXCR3; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERCELLULAR ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; BRAIN MALARIA; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; ENDOTHELIUM CELL; ERYTHROCYTE; GENE EXPRESSION; IMMUNOCOMPETENT CELL; LYMPHOCYTIC INFILTRATION; MALARIA; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SURVIVAL; T LYMPHOCYTE; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CHEMOKINE CXCL9; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; IMMUNOLOGIC FACTORS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON-BETA; MALARIA, CEREBRAL; MICE; MICE, INBRED C57BL; PLASMODIUM BERGHEI; RECEPTORS, CXCR3; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79953317241     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00810-10     Document Type: Article

References (27)

1. Armah, H. B., et al. 2007. Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. Malar. J. 6:147.
2. Campanella, G. S., et al. 2008. Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria. Proc. Natl. Acad. Sci. U. S. A. 105:4814-4819.
3. Chakravorty, S. J., and A. Craig. 2005. The role of ICAM-1 in Plasmodium falciparum cytoadherence. Eur. J. Cell Biol. 84:15-27.
4. Detrick, B., and J. J. Hooks. 2010. Immune regulation in the retina. Immunol. Res. 47:153-161.
5. Frangogiannis, N. G. 2007. Chemokines in ischemia and reperfusion. Thromb. Haemost. 97:738-747.
6. Gramaglia, I., et al. 2006. Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria. Nat. Med. 12:1417-1422.
7. Grau, G. E., and J. N. Lou. 1995. Experimental cerebral malaria: possible new mechanisms in the TNF-induced microvascular pathology. Soz. Praventivmed. 40:50-57.
8. Grau, G. E., et al. 1993. TNF-induced microvascular pathology: active role for platelets and importance of the LFA-1/ICAM-1 interaction. Eur. Cytokine Netw. 4:415-419.
9. Hansen, D. S., N. J. Bernard, C. Q. Nie, and L. Schofield. 2007. NK cells stimulate recruitment of CXCR3+ T cells to the brain during Plasmodium berghei-mediated cerebral malaria. J. Immunol. 178:5779-5788.
10. Hooks, J. J., C. N. Nagineni, L. C. Hooper, K. Hayashi, and B. Detrick. 2008. IFN-beta provides immuno-protection in the retina by inhibiting ICAM-1 and CXCL9 in retinal pigment epithelial cells. J. Immunol. 180:3789-3796.
11. Idro, R., et al. 2007. Burden, features, and outcome of neurological involvement in acute falciparum malaria in Kenyan children. JAMA 297:2232-2240.
12. Kumar, M. V., C. N. Nagineni, M. S. Chin, J. J. Hooks, and B. Detrick. 2004. Innate immunity in the retina: Toll-like receptor (TLR) signaling in human retinal pigment epithelial cells. J. Neuroimmunol. 153:7-15.
13. Lou, J., et al. 1997. Platelets play an important role in TNF-induced microvascular endothelial cell pathology. Am. J. Pathol. 151:1397-1405.
14. Luster, A. D., R. Alon, and U. H. von Andrian. 2005. Immune cell migration in inflammation: present and future therapeutic targets. Nat. Immunol. 6:1182-1190.
15. Miu, J., N. H. Hunt, and H. J. Ball. 2008. Predominance of interferonrelated responses in the brain during murine malaria, as identified by microarray analysis. Infect. Immun. 76:1812-1824.
16. Murata, K., et al. 2007. Synergistic deposition of C4d by complementactivating and non-activating antibodies in cardiac transplants. Am. J. Transplant. 7:2605-2614.
17. National Research Council. 1996. Guide for the care and use of laboratory animals. National Academy Press, Washington, DC
18. National Institutes of Health. 2000. Public Health Service policy on humane care and use of laboratory animals. Office of Laboratory Animal Welfare, National Institutes of Health, Bethesda, MD.
19. Srivastava, K., et al. 2008. Platelet factor 4 mediates inflammation in experimental cerebral malaria. Cell Host Microbe 4:179-187.
20. Tanuma, N., H. Sakuma, A. Sasaki, and Y. Matsumoto. 2006. Chemokine expression by astrocytes plays a role in microglia/macrophage activation and subsequent neurodegeneration in secondary progressive multiple sclerosis. Acta Neuropathol. (Berl.) 112:195-204.
21. Tripathi, A. K., D. J. Sullivan, and M. F. Stins. 2007. Plasmodium falciparum-infected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers. J. Infect. Dis. 195:942-950.
22. Tripathi, A. K., D. J. Sullivan, and M. F. Stins. 2006. Plasmodium falciparuminfected erythrocytes increase intercellular adhesion molecule 1 expression on brain endothelium through NF-kappaB. Infect. Immun. 74:3262-3270.
23. Van den Steen, P. E., et al. 2008. CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFNgamma-induced chemokines. Eur. J. Immunol. 38:1082-1095.
24. van der Heyde, H. C., J. Nolan, V. Combes, I. Gramaglia, and G. E. Grau. 2006. A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction. Trends Parasitol. 22:503-508.
25. Vigario, A. M., et al. 2007. Recombinant human IFN-alpha inhibits cerebral malaria and reduces parasite burden in mice. J. Immunol. 178:6416-6425.
26. Yamakuchi, M., et al. 2007. Antibody to human leukocyte antigen triggers endothelial exocytosis. Proc. Natl. Acad. Sci. U. S. A. 104:1301-1306.
27. Yanez, D. M., D. D. Manning, A. J. Cooley, W. P. Weidanz, and H. C. van der Heyde. 1996. Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria. J. Immunol. 157:1620-1624.