Reassortment and mutations associated with emergence and spread of oseltamivir-resistant seasonal influenza A/H1N1 viruses in 2005-2009

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Yang, Ji Rong ^a   Lin, Yu Cheng ^a   Huang, Yuan Pin ^a   Su, Chun Hui ^a   Lo, Je ^a   Ho, Yu Lin ^a   Yao, Ching Yuan ^a   Hsu, Li Ching ^a   Wu, Ho Sheng ^a,b   Liu, Ming Tsan ^a  

^a CENTER FOR DISEASE CONTROL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

OSELTAMIVIR; SIALIDASE; ANTIVIRUS AGENT;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIVIRAL RESISTANCE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC REASSORTMENT; GENETIC VARIABILITY; HUMAN; INFLUENZA VIRUS A H1N1; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PROCESS OPTIMIZATION; SEASONAL INFLUENZA; SEQUENCE ANALYSIS; STRAIN DIFFERENCE; TAIWAN; VIRUS STRAIN; ANIMAL; CELL LINE; DOG; DRUG EFFECT; EPIDEMIC; GENETICS; INFLUENZA; METABOLISM; MOLECULAR GENETICS; MUTATION; PATHOGENICITY; VIROLOGY;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DOGS; DRUG RESISTANCE, VIRAL; EPIDEMICS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MOLECULAR SEQUENCE DATA; MUTATION; NEURAMINIDASE; OSELTAMIVIR; REASSORTANT VIRUSES; TAIWAN;

EID: 79953315201     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018177     Document Type: Article

References (37)

1. Bright RA, Medina MJ, Xu X, Perez-Oronoz G, Wallis TR, et al. (2005) Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. Lancet 366: 1175-1181.
2. Deyde VM, Xu X, Bright RA, Shaw M, Smith CB, et al. (2007) Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide. J Infect Dis 196: 249-257.
3. Hauge SH, Dudman S, Borgen K, Lackenby A, Hungnes O, (2009) Oseltamivir-resistant influenza viruses A (H1N1), Norway, 2007-08. Emerg Infect Dis 15: 155-162.
4. Hurt AC, Ernest J, Deng YM, Iannello P, Besselaar TG, et al. (2009) Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa. Antiviral Res 83: 90-93.
5. Meijer A, Lackenby A, Hungnes O, Lina B, van-der-Werf S, et al. (2009) Oseltamivir-resistant influenza virus A (H1N1), Europe, 2007-08 season. Emerg Infect Dis 15: 552-560.
6. Casalegno JS, Bouscambert-Duchamp M, Caro V, Schuffenecker I, Sabatier M, et al. (2010) Oseltamivir-resistant influenza A(H1N1) viruses in south of France, 2007/2009. Antiviral Res 87: 242-248.
7. Lackenby A, Hungnes O, Dudman SG, Meijer A, Paget WJ, et al. (2008) Emergence of resistance to oseltamivir among influenza A(H1N1) viruses in Europe. Euro Surveill 13: pii = 8026.
8. Dharan NJ, Gubareva LV, Meyer JJ, Okomo-Adhiambo M, McClinton RC, et al. (2009) Infections with oseltamivir-resistant influenza A(H1N1) virus in the United States. JAMA 301: 1034-1041.
9. WHO (2009) Influenza A virus resistance to oseltamivir and other antiviral medicines. Available: http://www.who.int/csr/disease/influenza/2008-9nhemisummaryreport/en/index.html. Accessed 2010 February 25.
10. Regoes RR, Bonhoeffer S, (2006) Emergence of drug-resistant influenza virus: population dynamical considerations. Science 312: 389-391.
11. Hall CB, Dolin R, Gala CL, Markovitz DM, Zhang YQ, et al. (1987) Children with influenza A infection: treatment with rimantadine. Pediatrics 80: 275-282.
12. Hayden FG, Sperber SJ, Belshe RB, Clover RD, Hay AJ, et al. (1991) Recovery of drug-resistant influenza A virus during therapeutic use of rimantadine. Antimicrob Agents Chemother 35: 1741-1747.
13. Bean WJ, Threlkeld SC, Webster RG, (1989) Biologic potential of amantadine-resistant influenza A virus in an avian model. J Infect Dis 159: 1050-1056.
14. Simonsen L, Viboud C, Grenfell BT, Dushoff J, Jennings L, et al. (2007) The genesis and spread of reassortment human influenza A/H3N2 viruses conferring adamantane resistance. Mol Biol Evol 24: 1811-1820.
15. Reece PA, (2007) Neuraminidase inhibitor resistance in influenza viruses. J Med Virol 79: 1577-1586.
16. Ward P, Small I, Smith J, Suter P, Dutkowski R, (2005) Oseltamivir (Tamiflu) and its potential for use in the event of an influenza pandemic. J Antimicrob Chemother 55 (Suppl 1): i5-i21.
17. Whitley RJ, Hayden FG, Reisinger KS, Young N, Dutkowski R, et al. (2001) Oral oseltamivir treatment of influenza in children. Pediatr Infect Dis J 20: 127-133.
18. Ives JA, Carr JA, Mendel DB, Tai CY, Lambkin R, et al. (2002) The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo. Antiviral Res 55: 307-317.
19. Monto AS, McKimm-Breschkin JL, Macken C, Hampson AW, Hay A, et al. (2006) Detection of influenza viruses resistant to neuraminidase inhibitors in global surveillance during the first 3 years of their use. Antimicrob Agents Chemother 50: 2395-2402.
20. Rameix-Welti MA, Enouf V, Cuvelier F, Jeannin P, van der Werf S, (2008) Enzymatic properties of the neuraminidase of seasonal H1N1 influenza viruses provide insights for the emergence of natural resistance to oseltamivir. PLoS Pathog 4: e1000103.
21. Gooskens J, Jonges M, Claas EC, Meijer A, van den Broek PJ, et al. (2009) Morbidity and mortality associated with nosocomial transmission of oseltamivir-resistant influenza A(H1N1) virus. JAMA 301: 1042-1046.
22. Ciancio BC, Meerhoff TJ, Kramarz P, Bonmarin I, Borgen K, et al. (2009) Oseltamivir-resistant influenza A(H1N1) viruses detected in Europe during season 2007-8 had epidemiologic and clinical characteristics similar to co-circulating susceptible A(H1N1) viruses. Euro Surveill 14: pii = 19412.
23. Baz M, Abed Y, Simon P, Hamelin ME, Boivin G, (2010) Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses. J Infect Dis 201: 740-745.
24. WHO (2009) Influenza A(H1N1) virus resistance to oseltamivir- 2008/2009 influenza season, northern hemisphere. Available: http://www.who.int/csr/disease/influenza/H1N1webupdate20090318%20ed_ns.pdf. Accessed 2011 February 10.
25. Baranovich T, Saito R, Suzuki Y, Zaraket H, Dapat C, et al. (2010) Emergence of H274Y oseltamivir-resistant A(H1N1) influenza viruses in Japan during the 2008-2009 season. J Clin Virol 47: 23-28.
26. Garten RJ, Davis CT, Russell CA, Shu B, Lindstrom S, et al. (2009) Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science 325: 197-201.
27. Nelson MI, Holmes EC, (2007) The evolution of epidemic influenza. Nat Rev Genet 8: 196-205.
28. Nelson MI, Viboud C, Simonsen L, Bennett RT, Griesemer SB, et al. (2008) Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918. PLoS Pathog 4: e1000012.
29. Barr IG, McCauley J, Cox N, Daniels R, Engelhardt OG, et al. (2010) Epidemiological, antigenic and genetic characteristics of seasonal influenza A(H1N1), A(H3N2) and B influenza viruses: basis for the WHO recommendation on the composition of influenza vaccines for use in the 2009-2010 Northern Hemisphere season. Vaccine 28: 1156-1167.
30. Mukaigawa J, Nayak DP, (1991) Two signals mediate nuclear localization of influenza virus (A/WSN/33) polymerase basic protein 2. J Virol 65: 245-253.
31. Yang ZY, Wei CJ, Kong WP, Wu L, Xu L, et al. (2007) Immunization by avian H5 influenza hemagglutinin mutants with altered receptor binding specificity. Science 317: 825-828.
32. Bloom JD, Gong LI, Baltimore D, (2010) Permissive secondary mutations enable the evolution of influenza oseltamivir resistance. Science 328: 1272-1275.
33. Cheng PK, Leung TW, Ho EC, Leung PC, Ng AY, et al. (2009) Oseltamivir- and amantadine-resistant influenza viruses A (H1N1). Emerg Infect Dis 15: 966-968.
34. Cheng PK, To AP, Leung TW, Leung PC, Lee CW, et al. (2010) Oseltamivir- and amantadine-resistant influenza virus A (H1N1). Emerg Infect Dis 16: 155-156.
35. Jian JW, Chen GW, Lai CT, Hsu LC, Chen PJ, et al. (2008) Genetic and epidemiological analysis of influenza virus epidemics in Taiwan during 2003 to 2006. J Clin Microbiol 46: 1426-1434.
36. Bao Y, Bolotov P, Dernovoy D, Kiryutin B, Zaslavsky L, et al. (2008) The Influenza Virus Resource at the National Center for Biotechnology Information. J Virol 82: 596-601.
37. Tamura K, Dudley J, Nei M, Kumar S, (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 24: 1596-1599.