Perturbation of the quinone-binding site of complex II alters the electronic properties of the proximal [3Fe-4S] iron-sulfur cluster

Journal of Biological Chemistry

Volumn 286, Issue 14, 2011, Pages 12756-12765

  Ruprecht, Jonathan ^a,e   Iwata, So ^a   Rothery, Richard A ^b   Weiner, Joel H ^b   Maklashina, Elena ^c,d   Cecchini, Gary ^c,d  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF ALBERTA   (Canada)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHARGED RESIDUES; FUMARATES; HYDROGEN BONDINGS; IRON-SULFUR CLUSTERS; KINETIC CHARACTERIZATION; MUTANT ENZYMES; OXIDOREDUCTASES; REDOX POTENTIALS; REDOX PROPERTY; STEADY STATE; UBIQUINONE; X RAY STRUCTURAL ANALYSIS;

AMINO ACIDS; CATALYSIS; CATALYSTS; ELECTRONIC PROPERTIES; ESCHERICHIA COLI; HYDROGEN BONDS; IRON COMPOUNDS; KETONES; PLANTS (BOTANY); REDOX REACTIONS; SECONDARY BATTERIES; STRUCTURAL ANALYSIS; SULFUR;

ENZYMES;

HISTIDINE; IRON SULFUR PROTEIN; MENAQUINOL FUMARATE OXIDOREDUCTASE; QUINONE DERIVATIVE; SUCCINATE DEHYDROGENASE (UBIQUINONE); THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROGEN BOND; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; STEADY STATE;

BENZOQUINONES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX II; ESCHERICHIA COLI PROTEINS; IRON; MUTAGENESIS, SITE-DIRECTED; SULFUR;

ESCHERICHIA COLI;

EID: 79953308856     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.209874     Document Type: Article

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