Histone deacetylase 1 is required for exocrine pancreatic epithelial proliferation in development and cancer

Cancer Biology and Therapy

Volumn 11, Issue 7, 2011, Pages 659-670

  Zhou, Weiqiang ^a,b   Liang, I Chau ^a,c   Yee, Nelson S ^a  

^a UNIVERSITY OF IOWA   (United States)

^b CHINA MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

Development; Exocrine pancreas; Hedgehog; Histone deacetylase 1; Pancreatic adenocarcinoma; Pancreatic cancer; Proliferation

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; HISTONE DEACETYLASE 1; RNA; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIUM; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; LOSS OF FUNCTION MUTATION; MORPHOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS; PANCREAS ADENOCARCINOMA; PANCREAS EPITHELIUM PROLIFERATION; PROTEIN FUNCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION; ZEBRA FISH;

ACETYLATION; ADENOCARCINOMA; ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE DEACETYLASE 1; HISTONES; HUMANS; MODELS, ANIMAL; PANCREAS, EXOCRINE; PANCREATIC NEOPLASMS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ZEBRAFISH;

EID: 79953304257     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.11.7.14720     Document Type: Article

References (52)

1. Haberland M, Montgomery RL, Olson EN. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet 2009; 10:32-42.
2. Brunmeir R, Lagger S, Seiser C. Histone deacetylase 1 and 2-controlled embryonic development and cell differentiation. Int J Dev Biol 2009; 53:275-89.
3. Choi JH, Kown HJ, Yoon BI, Kim JH, Han SU, Joo HJ, et al. Expression profile of histone deacetylase 1 in gastric cancer tissue. Jpn J Cancer Res 2001; 92:1300-4. (Pubitemid 34036893)
4. Kim JH, Choi YK, Kwon HJ, Yang HK, Choi JH, Kim DY. Downregulation of gelsolin and retinoic acid receptor beta expression in gastric cancer tissues through histone deacetylase 1. J Gastroenterol Hepatol 2004; 19:218-24.
5. Halkidou K, Gaughan L, Cook S, Leung HY, Neal DE, Robson CN. Upregulation and nuclear recruitment to HDAC1 in hormone refractory prostate cancer. Prostate 2004; 59:177-89. (Pubitemid 38481229)
6. Krusche CA, Wulfing P, Kersting C, Vloet A, Bocker W, Kiesel L, et al. Histone deacetylase-1 and -3 protein expression in human breast cancer: a tissue microarray analysis. Breast Cancer Res Treat 2005; 90:15-23. (Pubitemid 40486997)
7. Nakagawa M, Oda Y, Eguchi T, Aishima SI, Yao T, Hosoi F, et al. Expression profile of class I histone deacetylases in human cancer tissues. Oncol Rep 2007; 18:769-74.
8. Glaser KB, Li J, Staver M, Ru-Qi W, Albert DH, Davidsen SK. Role of class I and class II histone deacetylases in carcinoma cells using siRNA. Biochem Biophys Res Commun 2003; 310:529-36. (Pubitemid 37163696)
9. Senese S, Zaragoza K, Minardi S, Muradore I, Ronzoni S, Passafaro A, et al. Role for histone deacetylase 1 in human tumor cell proliferation. Mol Cell Biol 2007; 27:4784-95. (Pubitemid 47016131)
10. Haberland M, Johnson A, Mokalled MH, Montgomery RL, Olson EN. Genetic dissection of histone deacetylase requirement in tumor cells. Proc Natl Acad Sci USA 2009; 106:7751-5.
11. Yee NS, Yusuff S, Pack M. Zebrafish pdx1 morphant displays defects in pancreas development and digestive organ chirality and potentially identifies a multipotent pancreas progenitor cell. Genesis 2001; 30:137-40. (Pubitemid 32730759)
12. Lin JW, Biankin AV, Horb ME, Ghosh B, Prasad NB, Yee NS, et al. Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas. Dev Biol 2004; 270:474-86. (Pubitemid 38748566)
13. Zecchin E, Mavropoulos A, Devos N, Filippi A, Tiso N, Meyer D, et al. Evolutionary conserved role of ptfla in the specification of exocrine pancreatic fates. Dev Biol 2004; 268:174-84. (Pubitemid 38367859)
14. Yee NS, Pack M. Zebrafish as a model for pancreatic cancer research. Meth Mol Med 2005; 130:273-98.
15. Yee NS, Lorent K, Pack M. Exocrine pancreas development in zebrafish. Dev Biol 2005; 284:84-101. (Pubitemid 41096726)
16. Yee NS, Gong W, Huang Y, Lorent K, Dolan AC, Maraia RJ, et al. Mutation of RNA pol III subunit rpc2/polr3b leads to deficiency of subunit rpc11 and disrupts zebrafish digestive development. PLoS Biol 2007; 5:2484-92. (Pubitemid 350276924)
17. Yee NS. Zebrafish as a biological system for identifying and evaluating therapeutic targets and compounds. In: Han H, Grippo PJ, Ed. Drug discovery in pancreatic cancer. New York: Springer 2010; 95-112.
18. 2+- sensitive Socs3a signaling in development and cancer. Dis Model Mech 2011; 4:240-54.
19. Matthews RP, Lorent K, Manoral-Mobias R, Huang Y, Gong W, Murray IVJ, et al. TNFα-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosyl-homocysteine hydrolase. Development 2009; 136:865-75.
20. Koorstra JB, Hustinx SR, Offerhaus GJ, Maitra A. Pancreatic carcinogenesis. Pancreatology 2008; 8:110-25. (Pubitemid 351670364)
21. Omura N, Goggins M. Epigenetics and epigenetic alterations in pancreatic cancer. Int J Clin Exp Pathol 2009; 2:310-26.
22. Garcia-Morales P, Gomez-Martinez A, Carrato A, Martinez-Lacaci I, Barbera VM, Soto JL, et al. Histone deacetylase inhibitors induced caspase-independent apoptosis in human pancreatic adenocarcinoma cell lines. Mol Cancer Ther 2005; 4:1222-30. (Pubitemid 41149570)
23. 2-M cell cycle arrest and apoptosis in pancreatic cancer cell lines. Cancer Lett 2006; 237:143-54.
24. Arnold NB, Arkus N, Gunn J, Korc M. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces growth inhibition and enhances gemcitabine-induced cell death in pancreatic cancer. Clin Cancer Res 2007; 13:18-26. (Pubitemid 46121848)
25. Kumagai T, Wakimoto N, Yin D, Gery S, Kawamata N, Takai N, et al. Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells. Int J Cancer 2007; 121:656-65. (Pubitemid 46986501)
26. Haefner M, Bluethner T, Niederhagen T, Moebius C, Wittekind C, Mossner J, et al. Experimental treatment of pancreatic cancer with two novel histone deacetylase inhibitors. World J Gastroenterol 2008; 14:3681-92.
27. Jones J, Bentas W, Blaheta RA, Makarevic J, Hudak L, Wedel S, et al. Modulation of adhesion and growth of colon and pancreatic cancer cells by the histone deacetylase inhibitor valproic acid. Int J Mol Med 2008; 22:293-9.
28. Pellizzaro C, Speranza A, Zorzet S, Crucil I, Sava G, Scarlata I, et al. Inhibition of human pancreatic cell line MIA PaCa2 proliferation by HA-but, a hyaluronic butyric ester: A preliminary report. Pancreas 2008; 36:15-23.
29. Chun SG, Zhou W, Yee NS. Combined targeting of histone deacetylases and hedgehog signaling produces enhanced cytotoxicity in pancreatic cancer. Cancer Biol Ther 2009; 8:1328-39.
30. Amsterdam A, Burgess S, Golling G, Chen W, Sun Z, Townsend K, et al. A large-scale insertional mutagenesis screen in zebrafish. Genes Dev 1999; 13:2713-24. (Pubitemid 29508558)
31. Golling G, Amsterdam A, Sun Z, Antonelli M, Maldonado E, Chen W, et al. Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Nat Genet 2002; 31:135-40.
32. Amsterdam A, Nissen RM, Sun Z, Swindell EC, Farrington S, Hopkins N. Identification of 315 genes essential for early zebrafish development. Proc Natl Acad Sci 2004; 101:12792-7. (Pubitemid 39167537)
33. Kouzarides T, Berger SL. Chromatin modifications and their mechanism of action. In: Allis CD, Jenuwein T, Reinberg D, Caparros ML, Ed. Epigenetics. New York: Cold Spring Harbor Laboratory Press 2007; 196.
34. Okada H, Mak TW. Pathways of apoptotic and nonapoptotic death in tumour cells. Nat Rev Cancer 2004; 4:592-603. (Pubitemid 39025054)
35. Morton JP, Mongeau ME, Klimstra DS, Morris JP, Lee YC, Kawaguchi Y, et al. Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis. Proc Natl Acad Sci 2006; 104:5103-8. (Pubitemid 47186183)
36. Farooq M, Sulochana KN, Pan X, To J, Sheng D, Gong Z, et al. Histone Deacetylase 3 (hdac3) is specifically required for liver development in zebrafish. Dev Biol 2008; 317:336-53.
37. Noel ES, Casal-Sueiro A, Busch-Nentwich E, Verkade H, Dong PDS, Stemple DL, et al. Organ-specific requirements for Hdac1 in liver and pancreas formation. Dev Biol 2008; 322:237-50.
38. Lagger G, O'Carroll D, Rembold M, Khier H, Tischler J, Weitzer G, et al. Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression. EMBO J 2002; 21:2672-81. (Pubitemid 34619383)
39. Ma P, Schultz RM. Histone deacetylase 1 (HDAC1) regulates histone acetylation, development and gene expression in preimplantation mouse embryo. Dev Biol 2008; 319:110-20.
40. Cunliffe VT. Histone deacetylases 1 is required to repress Notch target gene expression during zebrafish neurogenesis and to maintain the production of motoneurones in response to hedgehog signaling. Development 2004; 131:2983-95. (Pubitemid 38997285)
41. diIorio PJ, Moss JB, Sbrogna JL, Karlstrom RO, Moss LG. Sonic hedgehog is required early in pancreatic islet development. Dev Biol 2002; 244:75-84.
42. Ouaïssi M, Cabral S, Tavares J, da Silva AC, Mathieu Daude F, Mas E, et al. Histone Deacetylase (HDAC) encoding gene expression in pancreatic cancer cell lines and cell sensitivity to HDAC inhibitors. Cancer Biol Ther 2008; 7:523-31. (Pubitemid 351847026)
43. Wang W, Gao J, Man XH, Li ZS, Gong YF. Significance of DNA methyltransferase-1 and histone deacetylase-1 in pancreatic cancer. Oncol Rep 2009; 21:1439-47.
44. Deer EL, Gonzalez-Hernandez J, Coursen JD, Shea JE, Ngatia J, Scaife CL, et al. Phenotype and genotpye of pancreatic cancer cell lines. Pancreas 2010; 39:425-35.
45. Miyake K, Yoshizumi T, Imura S, Sugimoto K, Batmunkh E, Kanemura H, et al. Expression of hypoxia-inducible factor-1(alpha), Histone deacetylase 1 and metastasis-associated protein 1 in pancreatic carcinoma. Pancreas 2008; 36:1-9.
46. Lagger G, Doetzlhofer A, Schuettengruber B, Haidweger E, Simboeck E, Tischler J, et al. The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene. Mol Cell Biol 2003; 23:2669-79. (Pubitemid 36403069)
47. Martin ST, Sato N, Dhara S, Chang R, Hustinx SR, Abe T, et al. Aberrant methylation of the human hedge-hog interacting protein (HHIP) gene in pancreatic neoplasms. Cancer Biol Ther 2005; 4:728-33. (Pubitemid 41351171)
48. Thayer SP, Pasca di Magliano M, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, et al. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 2003; 425:851-6. (Pubitemid 37355945)
49. KCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation. Nat Cell Biol 2010; 12:132-44.
50. th ed. Eugene, Oregon: University of Oregon Press 2007.
51. Yee NS, Zhou W, Lee M. Transient receptor potential channel TRPM8 is overexpressed and required for cellular proliferation in pancreatic adenocarcinoma. Cancer Lett 2010; 297:49-55.
52. Furukawa T, Duguid WP, Rosenberg L, Viallet J, Galloway DA, Tsao MS. Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16. Am J Path 1996; 148:1763-70. (Pubitemid 26171674)