Periodic transmeningeal muscimol maintains its antiepileptic efficacy over three weeks without inducing tolerance, in rats

Neuroscience Letters

Volumn 494, Issue 2, 2011, Pages 135-138

  Tang, Hai M ^a   French, Jacqueline A ^a   Kuzniecky, Ruben I ^a   Devinsky, Orrin ^a   Ludvig, Nandor ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetylcholine; Muscimol; Neocortical seizures; Tolerance; Transmeningeal drug administration

Indexed keywords

ACETYLCHOLINE; MUSCIMOL; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG TOLERANCE; ELECTROENCEPHALOGRAM; INTRACTABLE EPILEPSY; MALE; NEOCORTEX; NONHUMAN; PARIETAL CORTEX; PRIORITY JOURNAL; RAT; SEIZURE;

ANIMALS; ANTICONVULSANTS; CONVULSANTS; DRUG TOLERANCE; ELECTRODES, IMPLANTED; ELECTROENCEPHALOGRAPHY; EPILEPSY; GABA-A RECEPTOR AGONISTS; MALE; MENINGES; MUSCIMOL; RATS; RATS, LONG-EVANS; SEIZURES;

EID: 79953290953     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.02.075     Document Type: Article

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