The intracerebral administration of phenytoin using controlled-release polymers reduces experimental seizures in rats

Epilepsy Research

Volumn 48, Issue 3, 2002, Pages 145-155

  Tamargo, Rafael J ^a   Rossell, Lisa Ann ^a   Kossoff, Eric H ^a,b   Tyler, Betty M ^a   Ewend, Matthew G ^a   Aryanpur, John J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Cobalt chloride; Phenytoin; Polymer; Rat; Seizure

Indexed keywords

COBALT CHLORIDE; ETHYLENE VINYL ACETATE COPOLYMER; PHENYTOIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG EFFICACY; ELECTROCORTICOGRAPHY; ELECTRODE; HISTOPATHOLOGY; MALE; MORBIDITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE; WEIGHT GAIN;

ANIMALS; ANTICONVULSANTS; DELAYED-ACTION PREPARATIONS; DRUG EVALUATION, PRECLINICAL; INJECTIONS, INTRAVENTRICULAR; MALE; PHENYTOIN; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES;

EID: 0036199550     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(01)00330-8     Document Type: Article

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