Size dependent induction of proinflammatory cytokines and cytotoxicity of particulate beta-tricalciumphosphate in vitro

Biomaterials

Volumn 32, Issue 17, 2011, Pages 4067-4075

  Lange, Tobias ^a   Schilling, Arndt F ^a,c   Peters, Fabian ^b   Mujas, Jan ^a   Wicklein, Daniel ^a   Amling, Michael ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b Curasan AG   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Beta tricalciumphosphate; Cytotoxicity; Human PBMC; Inflammation; Particle size; Phagocytosis

Indexed keywords

BETA-TRICALCIUMPHOSPHATE; CALCIUM PHOSPHATE CERAMICS; CELLULAR RESPONSE; CYTOKINES; CYTOTOXIC; CYTOTOXIC EFFECTS; DIFFERENT SIZES; HUMAN PBMC; HUMAN PERIPHERAL BLOOD; IN-VITRO; INFLAMMATION; INFLAMMATORY REACTION; LACTATE DEHYDROGENASE; MORPHOLOGICAL ANALYSIS; PARTICLE COMPOSITION; PHAGOCYTOSIS; PRIMARY PARTICLE SIZE; PROINFLAMMATORY CYTOKINES; SIZE DEPENDENT;

ANTIGEN-ANTIBODY REACTIONS; CALCIUM PHOSPHATE; PARTICLE SIZE; PATHOLOGY;

CYTOTOXICITY;

BETA TRICALCIUMPHOSPHATE; BIOCERAMICS; CALCIUM PHOSPHATE; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 8; LACTATE DEHYDROGENASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CYTOKINE RELEASE; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; PARTICLE SIZE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

CALCIUM PHOSPHATES; CELLS, CULTURED; CYTOKINES; HUMANS; INFLAMMATION; L-LACTATE DEHYDROGENASE; LEUKOCYTES, MONONUCLEAR; PARTICLE SIZE; PHAGOCYTOSIS;

EID: 79953280054     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.02.039     Document Type: Article

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