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Volumn 2, Issue 3, 2011, Pages 471-479

Nuclear expression of N-myc downstream regulated gene 1/ Ca2+-associated protein 43 is closely correlated with tumor angiogenesis and poor survival in patients with gastric cancer

Author keywords

Gastric cancer; N myc downstream regulated gene 1 Ca2+ associated protein 43; Poor prognosis; Tumor angiogenesis; Tumor associated macrophages

Indexed keywords

BIOLOGICAL MARKER; CALCIUM ASSOCIATED PROTEIN 43; CD34 ANTIGEN; CD68 ANTIGEN; N MYC DOWNSTREAM REGULATED PROTEIN 1; UNCLASSIFIED DRUG;

EID: 79953275784     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2011.222     Document Type: Article
Times cited : (21)

References (42)
  • 1
    • 0030799666 scopus 로고    scopus 로고
    • A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms
    • Van Belzen N, Dinjens WN, Diesveld MP, et al: A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms. Lab Invest 77: 85-92, 1997.
    • (1997) Lab Invest , vol.77 , pp. 85-92
    • van Belzen, N.1    Dinjens, W.N.2    Diesveld, M.P.3
  • 2
    • 0032188908 scopus 로고    scopus 로고
    • Inhibition of tumor cell growth by RTP/rit42 and its responsiveness to p53 and DNA damage
    • Kurdistani SK, Arizti P, Reimer CL, Sugrue MM, Aaronson SA and Lee SW: Inhibition of tumor cell growth by RTP/rit42 and its responsiveness to p53 and DNA damage. Cancer Res 58: 4439-4444, 1998.
    • (1998) Cancer Res , vol.58 , pp. 4439-4444
    • Kurdistani, S.K.1    Arizti, P.2    Reimer, C.L.3    Sugrue, M.M.4    Aaronson, S.A.5    Lee, S.W.6
  • 4
    • 0033539903 scopus 로고    scopus 로고
    • Identification of new genes Ndr2 and Ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N-myc
    • Okuda T and Kondoh H: Identification of new genes Ndr2 and Ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N-myc. Biochem Biophys Res commun 266: 208-215, 1999.
    • (1999) Biochem Biophys Res commun , vol.266 , pp. 208-215
    • Okuda, T.1    Kondoh, H.2
  • 5
    • 0033006387 scopus 로고    scopus 로고
    • N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant
    • Shimono A, Okuda T and Kondoh H: N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant. Mech Dev 83: 39-52, 1999.
    • (1999) Mech Dev , vol.83 , pp. 39-52
    • Shimono, A.1    Okuda, T.2    Kondoh, H.3
  • 6
    • 0036184953 scopus 로고    scopus 로고
    • Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family
    • Qu X, Zhai Y, Wei H, et al: Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family. Mol Cell Biochem 229: 35-44, 2002.
    • (2002) Mol Cell Biochem , vol.229 , pp. 35-44
    • Qu, X.1    Zhai, Y.2    Wei, H.3
  • 7
    • 0033972140 scopus 로고    scopus 로고
    • Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer
    • Guan RJ, Ford HL, Fu Y, Li Y, Shaw LM and Pardee AB: Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer. Cancer Res 60: 749-755, 2000.
    • (2000) Cancer Res , vol.60 , pp. 749-755
    • Guan, R.J.1    Ford, H.L.2    Fu, Y.3    Li, Y.4    Shaw, L.M.5    Pardee, A.B.6
  • 8
    • 0037447321 scopus 로고    scopus 로고
    • The Drg-1 gene suppresses tumor metastasis in prostate cancer
    • Bandyopadhyay S, Pai SK, Gross SC, et al: The Drg-1 gene suppresses tumor metastasis in prostate cancer. Cancer Res 63: 1731-1736, 2003.
    • (2003) Cancer Res , vol.63 , pp. 1731-1736
    • Bandyopadhyay, S.1    Pai, S.K.2    Gross, S.C.3
  • 9
    • 33746900026 scopus 로고    scopus 로고
    • Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer
    • Angst E, Sibold S, Tiffon C, et al: Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer. Br J Cancer 95: 307-313, 2006.
    • (2006) Br J Cancer , vol.95 , pp. 307-313
    • Angst, E.1    Sibold, S.2    Tiffon, C.3
  • 10
    • 33744791138 scopus 로고    scopus 로고
    • 17Beta-estradiol induces down-regulation of Cap43/NDRG1/Drg-1, a putative differentiation-related and metastasis suppressor gene, in human breast cancer cells
    • Fotovati A, Fujii T, Yamaguchi M, et al: 17Beta-estradiol induces down-regulation of Cap43/NDRG1/Drg-1, a putative differentiation-related and metastasis suppressor gene, in human breast cancer cells. Clin Cancer Res 12: 3010-3018, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 3010-3018
    • Fotovati, A.1    Fujii, T.2    Yamaguchi, M.3
  • 11
    • 33745700194 scopus 로고    scopus 로고
    • Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43/NDRG1/Drg-1 through modulation of angiogenesis
    • Maruyama Y, Ono M, Kawahara A, et al: Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43/NDRG1/Drg-1 through modulation of angiogenesis. Cancer Res 66: 6233-6242, 2006.
    • (2006) Cancer Res , vol.66 , pp. 6233-6242
    • Maruyama, Y.1    Ono, M.2    Kawahara, A.3
  • 12
    • 33750480214 scopus 로고    scopus 로고
    • Decreased expression of NDRG1 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma
    • Ando T, Ishiguro H, Kimura M, et al: Decreased expression of NDRG1 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma. Dis Esophagus 19: 454-458, 2006.
    • (2006) Dis Esophagus , vol.19 , pp. 454-458
    • Ando, T.1    Ishiguro, H.2    Kimura, M.3
  • 13
    • 36048987378 scopus 로고    scopus 로고
    • Immunohistochemical expressions of Cap43 and Mina53 proteins in neuroblastoma
    • Fukahori S, Yano H, Tsuneoka M, et al: Immunohistochemical expressions of Cap43 and Mina53 proteins in neuroblastoma. J Pediatr Surg 42: 1831-1840, 2007.
    • (2007) J Pediatr Surg , vol.42 , pp. 1831-1840
    • Fukahori, S.1    Yano, H.2    Tsuneoka, M.3
  • 14
    • 34347215841 scopus 로고    scopus 로고
    • Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity
    • Koshiji M, Kumamoto K, Morimura K, et al: Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity. World J Gastroenterol 13: 2803-2810, 2007.
    • (2007) World J Gastroenterol , vol.13 , pp. 2803-2810
    • Koshiji, M.1    Kumamoto, K.2    Morimura, K.3
  • 15
    • 73749084834 scopus 로고    scopus 로고
    • N-myc downstream regulated gene1/Cap43 may play an important role in malignant progression of prostate cancer, in its close association with E-cadherin
    • Song YS, Oda Y, Hori M, et al: N-myc downstream regulated gene1/Cap43 may play an important role in malignant progression of prostate cancer, in its close association with E-cadherin. Human Pathol 41: 214-222, 2010.
    • (2010) Human Pathol , vol.41 , pp. 214-222
    • Song, Y.S.1    Oda, Y.2    Hori, M.3
  • 16
    • 18244390251 scopus 로고    scopus 로고
    • Drg1 expression in 131 colorectal liver metastases: Correlation with clinical variables and patient outcomes
    • Shah MA, Kemeny N, Hummer A, et al: Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes. Clin Cancer Res 11: 3296-3302, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 3296-3302
    • Shah, M.A.1    Kemeny, N.2    Hummer, A.3
  • 17
    • 33845705732 scopus 로고    scopus 로고
    • Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma
    • Chua MS, Sun H, Cheung ST, et al: Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma. Mod Pathol 20: 76-83, 2007.
    • (2007) Mod Pathol , vol.20 , pp. 76-83
    • Chua, M.S.1    Sun, H.2    Cheung, S.T.3
  • 18
    • 42649098571 scopus 로고    scopus 로고
    • Cap43/NDRG1/Drg-1 is a molecular target for angiogenesis and a prognostic indicator in cervical adenocarcinoma
    • Nishio S, Ushijima K, Tsuda N, et al: Cap43/NDRG1/Drg-1 is a molecular target for angiogenesis and a prognostic indicator in cervical adenocarcinoma. Cancer Lett 264: 36-43, 2008.
    • (2008) Cancer Lett , vol.264 , pp. 36-43
    • Nishio, S.1    Ushijima, K.2    Tsuda, N.3
  • 19
    • 64949182097 scopus 로고    scopus 로고
    • Overexpression of Cap43 is associated with malignant status of esophageal cancer
    • Sohda M, Mochida Y, Kato H, et al: Overexpression of Cap43 is associated with malignant status of esophageal cancer. Anticancer Res 29: 965-970, 2009.
    • (2009) Anticancer Res , vol.29 , pp. 965-970
    • Sohda, M.1    Mochida, Y.2    Kato, H.3
  • 20
    • 50849085751 scopus 로고    scopus 로고
    • The iron-regulated metastasis suppressor, Ndrg-1: Identification of novel molecular targets
    • Kovacevic Z, Fu D and Richardson DR: The iron-regulated metastasis suppressor, Ndrg-1: identification of novel molecular targets. Biochim Biophys Acta 1783: 1981-1992, 2008.
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 1981-1992
    • Kovacevic, Z.1    Fu, D.2    Richardson, D.R.3
  • 21
    • 67449110970 scopus 로고    scopus 로고
    • N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of IKKbeta expression
    • Hosoi F, Izumi H, Kawahara A, et al: N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of IKKbeta expression. Cancer Res 69: 4983-4991, 2009.
    • (2009) Cancer Res , vol.69 , pp. 4983-4991
    • Hosoi, F.1    Izumi, H.2    Kawahara, A.3
  • 22
    • 77952745809 scopus 로고    scopus 로고
    • Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells
    • Murakami Y, Hosoi F, Izumi H, et al: Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells. Biochem Biophysical Res Commun 396: 376-381, 2010.
    • (2010) Biochem Biophysical Res Commun , vol.396 , pp. 376-381
    • Murakami, Y.1    Hosoi, F.2    Izumi, H.3
  • 23
    • 3142644996 scopus 로고    scopus 로고
    • Tumour-associated macrophages as a prototypic type II polarised phagocyte population: Role in tumour progression
    • Mantovani A, Allavena P and Sica A: Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression. Eur J Cancer 40: 1660-1667, 2004.
    • (2004) Eur J Cancer , vol.40 , pp. 1660-1667
    • Mantovani, A.1    Allavena, P.2    Sica, A.3
  • 24
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW: Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 4: 71-78, 2004.
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 25
    • 49749124618 scopus 로고    scopus 로고
    • Molecular links between tumor angiogenesis and inflammation: Inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy
    • Ono M: Molecular links between tumor angiogenesis and inflammation: inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy. Cancer Sci 99: 1501-1506, 2008.
    • (2008) Cancer Sci , vol.99 , pp. 1501-1506
    • Ono, M.1
  • 26
    • 34347226359 scopus 로고    scopus 로고
    • Tumor-associated macrophages press the angiogenic switch in breast cancer
    • Lin EY and Pollard JW: Tumor-associated macrophages press the angiogenic switch in breast cancer. Cancer Res 67: 5064-5066, 2007.
    • (2007) Cancer Res , vol.67 , pp. 5064-5066
    • Lin, E.Y.1    Pollard, J.W.2
  • 27
    • 34248172324 scopus 로고    scopus 로고
    • Altered macrophage differentiation and immune dysfunction in tumor development
    • Sica A and Bronte V: Altered macrophage differentiation and immune dysfunction in tumor development. J Clin invest 117: 1155-1166, 2007.
    • (2007) J Clin invest , vol.117 , pp. 1155-1166
    • Sica, A.1    Bronte, V.2
  • 28
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • Lewis CE and Pollard JW: Distinct role of macrophages in different tumor microenvironments. Cancer Res 66: 605-612, 2006.
    • (2006) Cancer Res , vol.66 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 29
    • 27644549559 scopus 로고    scopus 로고
    • Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1 betainduced neovascularization and tumor growth
    • Nakao S, Kuwano T, Tsutsumi-Miyahara C, et al: Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1 betainduced neovascularization and tumor growth. J Clin Invest 115: 2979-2991, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 2979-2991
    • Nakao, S.1    Kuwano, T.2    Tsutsumi-Miyahara, C.3
  • 30
    • 35548950622 scopus 로고    scopus 로고
    • Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis
    • Kimura YN, Watari K, Fotovati A, et al: Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis. Cancer Sci 98: 2009-2018, 2007.
    • (2007) Cancer Sci , vol.98 , pp. 2009-2018
    • Kimura, Y.N.1    Watari, K.2    Fotovati, A.3
  • 31
    • 49749146393 scopus 로고    scopus 로고
    • Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages
    • Hiraoka K, Zenmyo M, Watari K, et al: Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages. Cancer Sci 99: 1595-1602, 2008.
    • (2008) Cancer Sci , vol.99 , pp. 1595-1602
    • Hiraoka, K.1    Zenmyo, M.2    Watari, K.3
  • 32
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma: An attempt at a histo-clinical classification
    • Lauren P: The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma: an attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 64: 31-49, 1965.
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 31-49
    • Lauren, P.1
  • 33
    • 77954355363 scopus 로고    scopus 로고
    • Infiltration of thymidine phosphorylase-positive macrophages is closely associated with tumor angiogenesis and survival in intestinal type gastric cancer
    • Kawahara A, Hattori S, Akiba J, et al: Infiltration of thymidine phosphorylase-positive macrophages is closely associated with tumor angiogenesis and survival in intestinal type gastric cancer. Oncol Rep 24: 405-415, 2010.
    • (2010) Oncol Rep , vol.24 , pp. 405-415
    • Kawahara, A.1    Hattori, S.2    Akiba, J.3
  • 34
    • 0004292914 scopus 로고    scopus 로고
    • 3rd edition. Lippincott Williams & Wilkins, Philadelphia
    • Rothman KJ and Greenland S: Modern Epidemiology. 3rd edition. Lippincott Williams & Wilkins, Philadelphia, 1998.
    • (1998) Modern Epidemiology
    • Rothman, K.J.1    Greenland, S.2
  • 35
    • 0344825030 scopus 로고    scopus 로고
    • Cellular distribution of NDRG1 protein in the rat kidney and brain during normal postnatal development
    • Wakisaka Y, Furuta A, Masuda K, Morikawa W, Kuwano M and Iwaki T: Cellular distribution of NDRG1 protein in the rat kidney and brain during normal postnatal development. J Histochem Cytochem 51: 1515-1525, 2003.
    • (2003) J Histochem Cytochem , vol.51 , pp. 1515-1525
    • Wakisaka, Y.1    Furuta, A.2    Masuda, K.3    Morikawa, W.4    Kuwano, M.5    Iwaki, T.6
  • 37
    • 33847097342 scopus 로고    scopus 로고
    • Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinoma
    • Sibold S, Roh V, Keogh A, et al: Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinoma. FEBS Lett 581: 989-994, 2007.
    • (2007) FEBS Lett , vol.581 , pp. 989-994
    • Sibold, S.1    Roh, V.2    Keogh, A.3
  • 38
    • 0033817725 scopus 로고    scopus 로고
    • Vascular invasion and potential for tumor angiogenesis and metastasis in gastric carcinoma
    • Maehara Y, Kabashima A, Koga T, et al: Vascular invasion and potential for tumor angiogenesis and metastasis in gastric carcinoma. Surgery 128: 408-416, 2000.
    • (2000) Surgery , vol.128 , pp. 408-416
    • Maehara, Y.1    Kabashima, A.2    Koga, T.3
  • 39
    • 58149143253 scopus 로고    scopus 로고
    • Localization of N-myc downstream-regulated gene 1 in gastric cancer tissue
    • Inagaki Y, Tang W, Xu HL, et al: Localization of N-myc downstream-regulated gene 1 in gastric cancer tissue. Dig Liver Dis 41: 96-103, 2009.
    • (2009) Dig Liver Dis , vol.41 , pp. 96-103
    • Inagaki, Y.1    Tang, W.2    Xu, H.L.3
  • 40
    • 33845358660 scopus 로고    scopus 로고
    • The metastasis suppressor, Ndrg-1: A new ally in the fight against cancer
    • Kovacevic Z and Richardson DR: The metastasis suppressor, Ndrg-1: a new ally in the fight against cancer. Carcinogenesis 27: 2355-2366, 2006.
    • (2006) Carcinogenesis , vol.27 , pp. 2355-2366
    • Kovacevic, Z.1    Richardson, D.R.2
  • 41
    • 0035086097 scopus 로고    scopus 로고
    • The leukemogenic transcription factor E2a-Pbx1 induces expression of the putative N-myc and p53 target gene NDRG1 in Ba/F3 cells
    • Rutherford MN, Bayly GR, Matthews BP, et al: The leukemogenic transcription factor E2a-Pbx1 induces expression of the putative N-myc and p53 target gene NDRG1 in Ba/F3 cells. Leukemia 15: 362-370, 2001.
    • (2001) Leukemia , vol.15 , pp. 362-370
    • Rutherford, M.N.1    Bayly, G.R.2    Matthews, B.P.3
  • 42
    • 10344245574 scopus 로고    scopus 로고
    • NDRG1 is necessary for p53-dependent apoptosis
    • Stein S, Thomas EK, Herzog B, et al: NDRG1 is necessary for p53-dependent apoptosis. J Biol Chem 279: 48930-48940, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 48930-48940
    • Stein, S.1    Thomas, E.K.2    Herzog, B.3


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