Rhodococcus equi human clinical isolates enter and survive within human alveolar epithelial cells

Microbes and Infection

Volumn 13, Issue 5, 2011, Pages 438-446

  Ramos Vivas, J ^a   Pilares Ortega, L ^b   Remuzgo Martinez S ^a   Padilla, D ^c   Gutierrez Diaz J L ^b   Navas Mendez J ^b  

^a HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^b UNIVERSITY OF CANTABRIA   (Spain)

^c UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

Author keywords

Human alveolar cells; Intracellular pathogen; Rhodococcus equi

Indexed keywords

RNA 16S; VANCOMYCIN;

ARTICLE; BACTERIAL GROWTH; BACTERIUM ADHERENCE; BACTERIUM CULTURE; COLONY FORMING UNIT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; LUNG ALVEOLUS CELL; LUNG ALVEOLUS MACROPHAGE; MORPHOLOGY; NONHUMAN; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; RHODOCOCCUS EQUI;

ACTINOMYCETALES INFECTIONS; BACTERIAL ADHESION; CELL LINE; EPITHELIAL CELLS; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; PULMONARY ALVEOLI; RHODOCOCCUS EQUI; VIRULENCE;

HUMAN IMMUNODEFICIENCY VIRUS; RHODOCOCCUS EQUI;

EID: 79953273647     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2011.01.003     Document Type: Article

References (41)

1. von Bargen K., Haas A. Molecular and infection biology of the horse pathogen Rhodococcus equi. FEMS Microbiol. Rev. 2009, 33:870-891.
2. Yamshchikov A.V., Schuetz A., Lyon G.M. Rhodococcus equi infection. Lancet Infect. Dis. 2010, 10:350-359.
3. Giguere S., Prescott J.F. Clinical manifestations, diagnosis, treatment, and prevention of Rhodococcus equi infections in foals. Vet. Microbiol. 1997, 56:313-334.
4. Goodfellow M. Genus Rhodococcus. Bergey's Manual of Systematic Bacteriology 1986, vol. 4:2362-2371. The William & Wilkins Co., Baltimore, Md. P.H.A. Sneath, N.S. Mair, M.E. Sharpe, J.G. Holt (Eds.).
5. Ocampo-Sosa A.A., Lewis D.A., Navas J., Quigley F., Callejo R., Scortti M., Leadon D.P., Fogarty U., Vazquez-Boland J.A. Molecular epidemiology of Rhodococcus equi based on traA, vapA, and vapB virulence plasmid markers. J. Infect. Dis. 2007, 196:763-769.
6. Ladron N., Fernandez M., Aguero J., Gonzalez Zorn B., Vazquez-Boland J.A., Navas J. Rapid identification of Rhodococcus equi by a PCR assay targeting the choE gene. J. Clin. Microbiol. 2003, 41:3241-3245.
7. Pilares L., Aguero J., Vazquez-Boland J.A., Martinez-Martinez L., Navas J. Identification of atypical Rhodococcus-like clinical isolates as Dietzia spp. by 16S rRNA gene sequencing. J. Clin. Microbiol. 2010, 48:1904-1907.
8. Giguere S., Hondalus M.K., Yager J.A., Darrah P., Mosser D.M., Prescott J.F. Role of the 85-kilobase plasmid and plasmid-encoded virulence-associated protein A in intracellular survival and virulence of Rhodococcus equi. Infect. Immun. 1999, 67:3548-3557.
9. Takai S., Kobayashi C., Murakami K., Sasaki Y., Tsubaki S. Live virulent Rhodococcus equi, rather than killed or avirulent, elicits protective immunity to R. equi infection in mice. FEMS Immunol. Med. Microbiol. 1999, 24:1-9.
10. Takai S., Anzai T., Fujita Y., Akita O., Shoda M., Tsubaki S., Wada R. Pathogenicity of Rhodococcus equi expressing a virulence-associated 20 kDa protein (VapB) in foals. Vet. Microbiol. 2000, 76:71-80.
11. Byrne B.A., Prescott J.F., Palmer G.H., Takai S., Nicholson V.M., Alperin D.C., Hines S.A. Virulence plasmid of Rhodococcus equi contains inducible gene family encoding secreted proteins. Infect. Immun. 2001, 69:650-656.
12. Kanaly S.T., Hines S.A., Palmer G.H. Transfer of a CD4+ Th1 cell line to nude mice effects clearance of Rhodococcus equi from the lung. Infect. Immun. 1996, 64:1126-1132.
13. Madigan J.E., Hietala S., Muller N. Protection against naturally acquired Rhodococcus equi pneumonia in foals by administration of hyperimmune plasma. J. Reprod. Fertil. Suppl. 1991, 44:571-578.
14. Fernandez-Mora E., Polidori M., Luhrmann A., Schaible U.E., Haas A. Maturation of Rhodococcus equi-containing vacuoles is arrested after completion of the early endosome stage. Traffic 2005, 6:635-653.
15. Toyooka K., Takai S., Kirikae T. Rhodococcus equi can survive a phagolysosomal environment in macrophages by suppressing acidification of the phagolysosome. J. Med. Microbiol. 2005, 54:1007-1015.
16. Casadevall A. Evolution of intracellular pathogens. Annu. Rev. Microbiol. 2008, 62:19-33.
17. Ehrt S., Schnappinger D. Mycobacterial survival strategies in the phagosome: defence against host stresses. Cell. Microbiol. 2009, 11:1170-1178.
18. Mutimer M.D., Woolcock J.B. Some problems associated with the identification of Corinebaterium equi. Vet. Microbiol. 1981, 6:331-338.
19. Padilla D., Acosta F., Bravo J., Grasso V., Real F., Vivas J. Invasion and intracellular survival of Hafnia alvei strains in human epithelial cells. J. Appl. Microbiol. 2008, 105:1614-1622.
20. Harlow E.D.L. Immunizations. Antibodies, a Laboratory Manual 1988, 53-137. Cold Spring Harbor Laboratory, Cold Spring Harbor. L. EHaD (Ed.).
21. Padilla D., Acosta F., Garcia J.A., Real F., Vivas J.R. Temperature influences the expression of fimbriae and flagella in Hafnia alvei strains: an immunofluorescence study. Arch. Microbiol. 2009, 191:191-198.
22. Isberg R.R., Falkow S. A single genetic locus encoded by Yersinia pseudotuberculosis permits invasion of cultured animal cells by Escherichia coli K-12. Nature 1985, 317:262-264.
23. Cano D.A., Martinez-Moya M., Pucciarelli M.G., Groisman E.A., Casadesus J., Garcia-Del Portillo F. Salmonella enterica serovar Typhimurium response involved in attenuation of pathogen intracellular proliferation. Infect. Immun. 2001, 69:6463-6474.
24. Segura I., Casadesus J., Ramos-Morales F. Use of mixed infections to study cell invasion and intracellular proliferation of Salmonella enterica in eukaryotic cell cultures. J. Microbiol. Methods 2004, 56:83-91.
25. Jotwani R., Cutler C.W. Fimbriated Porphyromonas gingivalis is more efficient than fimbria-deficient P. gingivalis in entering human dendritic cells in vitro and induces an inflammatory Th1 effector response. Infect. Immun. 2004, 72:1725-1732.
26. Hondalus M.K., Diamond M.S., Rosenthal L.A., Springer T.A., Mosser D.M. The intracellular bacterium Rhodococcus equi requires Mac-1 to bind to mammalian cells. Infect. Immun. 1993, 61:2919-2929.
27. de la Pena-Moctezuma A., Prescott J.F. Association with HeLa cells by Rhodococcus equi with and without the virulence plasmid. Vet. Microbiol. 1995, 46:383-392.
28. Pizarro-Cerda J., Moreno E., Gorvel J.P. Invasion and intracellular trafficking of Brucella abortus in nonphagocytic cells. Microbes Infect./Institut Pasteur 2000, 2:829-835.
29. Mills S.D., Finlay B.B. Comparison of Salmonella typhi and Salmonella typhimurium invasion, intracellular growth and localization in cultured human epithelial cells. Microb. Pathog. 1994, 17:409-423.
30. Friis L.M., Pin C., Pearson B.M., Wells J.M. In vitro cell culture methods for investigating Campylobacter invasion mechanisms. J. Microbiol. Methods 2005, 61:145-160.
31. Byrne C.M., Clyne M., Bourke B. Campylobacter jejuni adhere to and invade chicken intestinal epithelial cells in vitro. Microbiology 2007, 153:561-569. (Reading, England).
32. Martin D.W., Mohr C.D. Invasion and intracellular survival of Burkholderia cepacia. Infect. Immun. 2000, 68:24-29.
33. Stevens M.P., Friebel A., Taylor L.A., Wood M.W., Brown P.J., Hardt W.D., Galyov E.E. A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity. J. Bacteriol. 2003, 185:4992-4996.
34. Dorn B.R., Leung K.L., Progulske-Fox A. Invasion of human oral epithelial cells by Prevotella intermedia. Infect. Immun. 1998, 66:6054-6057.
35. Isberg R.R., O'Connor T.J., Heidtman M. The Legionella pneumophila replication vacuole: making a cosy niche inside host cells. Nat. Rev. Microbiol. 2009, 7:13-24.
36. Howe D., Heinzen R.A. Coxiella burnetii inhabits a cholesterol-rich vacuole and influences cellular cholesterol metabolism. Cell. Microbiol. 2006, 8:496-507.
37. Berry R.E., Klumpp D.J., Schaeffer A.J. Urothelial cultures support intracellular bacterial community formation by uropathogenic Escherichia coli. Infect. Immun. 2009, 77:2762-2772.
38. Brumell J.H., Tang P., Zaharik M.L., Finlay B.B. Disruption of the Salmonella-containing vacuole leads to increased replication of Salmonella enterica serovar typhimurium in the cytosol of epithelial cells. Infect. Immun. 2002, 70:3264-3270.
39. Rahamat-Langendoen J.C., van Meurs M., Zijlstra J.G., Lo-Ten-Foe J.R. Disseminated Rhodococcus equi infection in a kidney transplant patient without initial pulmonary involvement. Diagn. Microbiol. Infect. Dis. 2009, 65:427-430.
40. Ulivieri S., Oliveri G. Cerebellar abscess due to Rhodococcus equi in an immunocompetent patient: case report and literature review. J. Neurosurg. Sci. 2006, 50:127-129.
41. Paasche S.R. Rhodococcus equi infection in a surgical wound. Clin. Lab. Sci. 2009, 22:141-145.