-
1
-
-
41549136422
-
Paths of convergence: Sirtuins in aging and neurodegeneration
-
DOI 10.1016/j.neuron.2008.03.015, PII S0896627308002614
-
Gan L, Mucke L. Paths of convergence: Sirtuins in aging and neurodegeneration. Neuron 2008;58:10-14. (Pubitemid 351467036)
-
(2008)
Neuron
, vol.58
, Issue.1
, pp. 10-14
-
-
Gan, L.1
Mucke, L.2
-
3
-
-
33750445309
-
NAD metabolism and sirtuins: Metabolic regulation of protein deacetylation in stress and toxicity
-
DOI 10.1208/aapsj080472
-
Yang TL, Sauve AA. NAD metabolism and sirtuins: Metabolic regulation of protein deacetylation in stress and toxicity. AAPS J 2006;8:E632-E643. (Pubitemid 44644162)
-
(2006)
AAPS Journal
, vol.8
, Issue.4
-
-
Yang, T.1
Sauve, A.A.2
-
4
-
-
47249108032
-
Sirtuins: Novel targets for metabolic disease in drug development
-
Jiang W. Sirtuins: Novel targets for metabolic disease in drug development. Biochem Biophys Res Commun 2008;373: 341-344.
-
(2008)
Biochem Biophys Res Commun
, vol.373
, pp. 341-344
-
-
Jiang, W.1
-
5
-
-
40849135481
-
The Sirtuin family: Therapeutic targets to treat diseases of aging
-
Milne JC, Denu JM. The Sirtuin family: Therapeutic targets to treat diseases of aging. Curr Opin Chem Biol 2008;12:11-17.
-
(2008)
Curr Opin Chem Biol
, vol.12
, pp. 11-17
-
-
Milne, J.C.1
Denu, J.M.2
-
6
-
-
34249083199
-
Sirtuins in mammals: Insights into their biological function
-
DOI 10.1042/BJ20070140
-
Michan S, Sinclair D. Sirtuins in mammals: Insights into their biological function. Biochem J 2007;404:1-13. (Pubitemid 46788079)
-
(2007)
Biochemical Journal
, vol.404
, Issue.1
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
8
-
-
33751113602
-
Mammalian sirtuins - Emerging roles in physiology, aging, and calorie restriction
-
DOI 10.1101/gad.1467506
-
Haigis MC, Guarente LP. Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction. Genes Dev 2006;20:2913-2921. (Pubitemid 44771725)
-
(2006)
Genes and Development
, vol.20
, Issue.21
, pp. 2913-2921
-
-
Haigis, M.C.1
Guarente, L.P.2
-
9
-
-
34547413569
-
Sirtuin functions in health and disease
-
DOI 10.1210/me.2007-0079
-
Yamamoto H, Schoonjans K, Auwerx J. Sirtuin functions in health and disease. Mol Endocrinol 2007;21:1745-1755. (Pubitemid 47173788)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.8
, pp. 1745-1755
-
-
Yamamoto, H.1
Schoonjans, K.2
Auwerx, J.3
-
10
-
-
34547875773
-
Sirtuins: Critical regulators at the crossroads between cancer and aging
-
DOI 10.1038/sj.onc.1210616, PII 1210616
-
Saunders LR, Verdin E. Sirtuins: Critical regulators at the crossroads between cancer and aging. Oncogene 2007;26: 5489-5504. (Pubitemid 47255930)
-
(2007)
Oncogene
, vol.26
, Issue.37
, pp. 5489-5504
-
-
Saunders, L.R.1
Verdin, E.2
-
11
-
-
12844271254
-
The emerging therapeutic potential of sirtuin-interacting drugs: From cell death to lifespan extension
-
DOI 10.1016/j.tips.2004.12.009, PII S0165614704003232
-
Porcu M, Chiarugi A. The emerging therapeutic potential of sirtuin-interacting drugs: From cell death to lifespan extension. Trends Pharmacol Sci 2005;26:94-103. (Pubitemid 40170172)
-
(2005)
Trends in Pharmacological Sciences
, vol.26
, Issue.2
, pp. 94-103
-
-
Porcu, M.1
Chiarugi, A.2
-
12
-
-
53249121556
-
Sirtuins-novel therapeutic targets to treat age-associated diseases
-
Lavu S, Boss O, Elliott P, Lambert P. Sirtuins-novel therapeutic targets to treat age-associated diseases. Nat Rev Drug Discov 2008;7:841-853.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 841-853
-
-
Lavu, S.1
Boss, O.2
Elliott, P.3
Lambert, P.4
-
13
-
-
56649085322
-
SIRT1: Roles in aging and cancer
-
Kim E, Um S. SIRT1: Roles in aging and cancer. BMB Rep 2008;41:751-756.
-
(2008)
BMB Rep
, vol.41
, pp. 751-756
-
-
Kim, E.1
Um, S.2
-
14
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
DOI 10.1146/annurev.biochem.73.011303.073651
-
Blander G, Guarente L. The Sir2 family of protein deacetylases. Annu Rev Biochem 2004;73:417-435. (Pubitemid 39050375)
-
(2004)
Annual Review of Biochemistry
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
15
-
-
0041733072
-
A call to fins! Zebrafish as a gerontological model
-
Gerhard G, Cheng K. A call to fins! Zebrafish as a gerontological model. Aging Cell 2002;1:104-111.
-
(2002)
Aging Cell
, vol.1
, pp. 104-111
-
-
Gerhard, G.1
Cheng, K.2
-
16
-
-
7944220591
-
The use of mature zebrafish (Danio rerio) as a model for human aging and disease
-
DOI 10.1016/j.cca.2004.04.001, PII S1532045604000699, Aquatic Animal Models of Human Disease
-
Keller E, Murtha J. The use of mature zebrafish (Danio rerio) as a model for human aging and disease. Comp Biochem Physiol C Toxicol Pharmacol 2004;138:335-341. (Pubitemid 39469068)
-
(2004)
Comparative Biochemistry and Physiology - C Toxicology and Pharmacology
, vol.138
, Issue.3
, pp. 335-341
-
-
Keller, E.T.1
Murtha, J.M.2
-
18
-
-
0034068307
-
Zebrafish: A model system for the study of human disease
-
DOI 10.1016/S0959-437X(00)00074-5
-
Dooley K, Zon L. Zebrafish: A model system for the study of human disease. Curr Opin Genet Dev 2000;10:252-256. (Pubitemid 30307241)
-
(2000)
Current Opinion in Genetics and Development
, vol.10
, Issue.3
, pp. 252-256
-
-
Dooley, K.1
Zon, L.I.2
-
19
-
-
3242714885
-
Functional aging and gradual senescence in zebrafish
-
DOI 10.1196/annals.1297.097
-
Kishi S. Functional aging and gradual senescence in zebrafish. Ann N Y Acad Sci 2004;1019:521-526. (Pubitemid 38951370)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1019
, pp. 521-526
-
-
Kishi, S.1
-
20
-
-
0347416782
-
Comparative aspects of zebrafish (Danio rerio) as a model for aging research
-
DOI 10.1016/j.exger.2003.10.022
-
Gerhard G. Comparative aspects of zebrafish (Danio rerio) as a model for aging research. Exp Gerontol 2003;38:1333-1341. (Pubitemid 38041221)
-
(2003)
Experimental Gerontology
, vol.38
, Issue.11-12
, pp. 1333-1341
-
-
Gerhard, G.S.1
-
21
-
-
35348980724
-
SIRT1 controls endothelial angiogenic functions during vascular growth
-
DOI 10.1101/gad.435107
-
Potente M, Ghaeni L, Baldessari D, Mostoslavsky R, Rossig L, Dequiedt F, et al. SIRT1 controls endothelial angiogenic functions during vascular growth. Genes Dev 2007;21: 2644-2658. (Pubitemid 47607673)
-
(2007)
Genes and Development
, vol.21
, Issue.20
, pp. 2644-2658
-
-
Potente, M.1
Ghaeni, L.2
Baldessari, D.3
Mostoslavsky, R.4
Rossig, L.5
Dequiedt, F.6
Haendeler, J.7
Mione, M.8
Dejana, E.9
Alt, F.W.10
Zeiher, A.M.11
Dimmeler, S.12
-
22
-
-
51249098543
-
A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development
-
Jones K, Alimov A, Rilo H, Jandacek R, Woollett L, Penberthy W. A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development. Nutr Metab (Lond) 2008;5:23.
-
(2008)
Nutr Metab (Lond)
, vol.5
, pp. 23
-
-
Jones, K.1
Alimov, A.2
Rilo, H.3
Jandacek, R.4
Woollett, L.5
Penberthy, W.6
-
23
-
-
3242763874
-
Expression of metallothionein gene during embryonic and early larval development in zebrafish
-
DOI 10.1016/j.aquatox.2004.05.004, PII S0166445X04001717
-
Chen W, John J, Lin C, Lin H, Wu S, Chang C. Expression of metallothionein gene during embryonic and early larval development in zebrafish. Aquat Toxicol 2004;69:215-227. (Pubitemid 38970048)
-
(2004)
Aquatic Toxicology
, vol.69
, Issue.3
, pp. 215-227
-
-
Chen, W.-Y.1
John, J.A.C.2
Lin, C.-H.3
Lin, H.-F.4
Wu, S.-C.5
Lin, C.-H.6
Chang, C.-Y.7
-
24
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
DOI 10.1091/mbc.E05-01-0033
-
Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 2005;16:4623-4635. (Pubitemid 41416446)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.10
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
26
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park S, et al. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 2008;135:907-918.
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mostoslavsky, R.4
Vann, J.5
Park, S.6
-
27
-
-
58149090925
-
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span
-
Kawahara T, Michishita E, Adler A, Damian M, Berber E, Lin M, et al. SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell 2009;136:62-74.
-
(2009)
Cell
, vol.136
, pp. 62-74
-
-
Kawahara, T.1
Michishita, E.2
Adler, A.3
Damian, M.4
Berber, E.5
Lin, M.6
-
28
-
-
1642503737
-
Linking genes to brain, behavior and neurological diseases: What can we learn from zebrafish?
-
DOI 10.1046/j.1601-183X.2003.00053.x
-
Guo S. Linking genes to brain, behavior and neurological diseases: What can we learn from zebrafish? Genes Brain Behav 2004;3:63-74. (Pubitemid 38405251)
-
(2004)
Genes, Brain and Behavior
, vol.3
, Issue.2
, pp. 63-74
-
-
Guo, S.1
-
29
-
-
12144273121
-
In vivo drug discovery in the zebrafish
-
DOI 10.1038/nrd1606
-
Zon L, Peterson R. In vivo drug discovery in the zebrafish. Nat Rev Drug Discov 2005;4:35-44. (Pubitemid 40109588)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.1
, pp. 35-44
-
-
Zon, L.I.1
Peterson, R.T.2
-
30
-
-
36249016246
-
A therapeutic role for sirtuins in diseases of aging?
-
DOI 10.1016/j.tibs.2007.09.008, PII S0968000407002423
-
Westphal CH, Dipp MA, Guarente L. A therapeutic role for sirtuins in diseases of aging? Trends Biochem Sci 2007;32: 555-560. (Pubitemid 350123051)
-
(2007)
Trends in Biochemical Sciences
, vol.32
, Issue.12
, pp. 555-560
-
-
Westphal, C.H.1
Dipp, M.A.2
Guarente, L.3
-
31
-
-
43749121572
-
Therapeutic role of sirtuins in neurodegenerative disease
-
Outeiro TF, Marques O, Kazantsev A. Therapeutic role of sirtuins in neurodegenerative disease. Biochim Biophys Acta 2008;1782:363-369.
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 363-369
-
-
Outeiro, T.F.1
Marques, O.2
Kazantsev, A.3
-
32
-
-
57749197168
-
Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway
-
Chen C, Yu W, Fu Y, Wang X, Li J, Wang W. Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway. Biochem Biophys Res Commun 2009;378:389-393.
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 389-393
-
-
Chen, C.1
Yu, W.2
Fu, Y.3
Wang, X.4
Li, J.5
Wang, W.6
-
33
-
-
70350524083
-
Resveratrol is not a direct activator of SIRT1 enzyme activity
-
Beher D, Wu J, Cumine S, Kim K, Lu S, Atangan L, et al. Resveratrol is not a direct activator of SIRT1 enzyme activity. Chem Biol Drug Des 2009;74:619-624.
-
(2009)
Chem Biol Drug Des
, vol.74
, pp. 619-624
-
-
Beher, D.1
Wu, J.2
Cumine, S.3
Kim, K.4
Lu, S.5
Atangan, L.6
-
34
-
-
77957975705
-
A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: Part 1
-
Kelly G. A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: Part 1. Altern Med Rev 2010;15:245-263.
-
(2010)
Altern Med Rev
, vol.15
, pp. 245-263
-
-
Kelly, G.1
|