Direct compression and moulding properties of co-extruded isomalt/drug mixtures

International Journal of Pharmaceutics

Volumn 235, Issue 1-2, 2002, Pages 159-168

  Ndindayino, F ^a   Vervaet, C ^a   Van Den Mooter, G ^b   Remon, J P ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Co extrusion; Direct compression; Direct moulding; Hydrochlorothiazide; Isomalt; Paracetamol

Indexed keywords

AEROSIL; ALCOHOL; DISACCHARIDE; HYDROCHLOROTHIAZIDE; ISOMALT; PARACETAMOL; STARCH GLYCOLATE SODIUM;

ARTICLE; CONCENTRATION RESPONSE; CRYSTALLIZATION; DRUG FORMULATION; DRUG MIXTURE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; DRUG STRUCTURE; DRUG TRANSFORMATION; INTERMETHOD COMPARISON; MICROSCOPY; PRIORITY JOURNAL; TABLET COMPRESSION; TABLET HARDNESS; TABLET PROPERTY; TENSILE STRENGTH;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; CARIOGENIC AGENTS; CHEMISTRY, PHARMACEUTICAL; DISACCHARIDES; DRUG COMBINATIONS; DRUG STABILITY; POWDERS; SOLUBILITY; SUGAR ALCOHOLS; TABLETS; TENSILE STRENGTH;

EID: 0037139360     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00994-2     Document Type: Article

References (24)

1. Injection moulding metal and ceramic powder
2. Investigation of dissolution enhancement of itraconazole by solid dispersion in superdisintegrants
3. A preliminary evaluation of injection moulding as a tabletting technology
4. Fast-melting tablets: Developments and technologies
5. Isomalt, a sugar substitute ideal for the manufacture of sugar-free and calorie-reduced confectionery
6. Ideal copolymers and the second order transitions of synthetic rubbers I. Non-crystalline copolymers
7. Properties of fused mannitol in compressed tablets
8. Improving drug solubility for oral delivery using solid dispersions
9. Influence of hydroxypropyl β-cyclodextrin on solubility and dissolution profile of ketoprofen in its solid dispersions
10. Characterization and evaluation of isomalt (Palatinit®) performance in direct compression
11. Direct compression properties of melt-extruded isomalt
12. Growth market for powder injection moulding
13. Solid dispersion of poorly water-soluble drugs: Early promises, subsequent problems and recent breakthroughs
14. On a general relation involving the glass temperature and coefficients of expansion of polymers
15. Effects of some polymers on the physicochemical and dissolution properties of hydrochlorothiazide II
16. Physicochemical aspects of drug release. XI. Tabletting properties of drug dispersions using xylitol as a carrier material
17. Preparation, tabletting and properties of solid dispersions of spironolactone
18. Palatinit®, the ideal ingredient for confectionery
19. Properties of solid dispersions of piroxicam in polyvinylpyrrolidone K-30
20. Evaluation of the compression behaviour of paracetamol tablets produced by dispersion in β-cyclodextrin. Part I: Scanning electron microscopic study of tablets
21. Compression study of paracetamol solid dispersion tablets