A Two-Species Drug Delivery Model is Required to Predict Deposition from Drug-Eluting Stents

Cardiovascular Engineering and Technology

Volumn 1, Issue 3, 2010, Pages 225-234

  Horner, Marc ^a   Joshi, S ^b   Dhruva, V ^c   Sett, S ^c   Stewart, S F C ^d  

^a ANSYS INC   (United States)

^b Fluent India Private Limited   (India)

^c Simulia   (United States)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Drug delivery computational methods; Drug eluting stents; Fluid mechanics; Solid mechanics

Indexed keywords

COMPUTATIONAL MODELING; CONVECTION DIFFUSION; CORONARY ARTERIES; DEPOSITION PATTERNS; DIFFUSION AND CONVECTION; DRUG TRANSPORT; DRUG-DELIVERY MODEL; DRUG-ELUTING STENTS; EQUILIBRIUM REACTIONS; FIRST LOOK; INTERCONVERSIONS; MODELING FRAMEWORKS; PARAMETRIC STUDY; PHYSICOCHEMICAL PROPERTY; PREFERENTIAL BINDING; RELATIVE REACTION RATES; RESIDENCE TIME; RESTENOSIS RATES; REVERSIBLE BINDING; SINGLE SPECIES; SOLID MECHANICS; THREE-DIMENSIONAL MODEL; UNBOUND STATE; VESSEL WALLS;

ARTIFICIAL ORGANS; BINDING SITES; BIOCHEMISTRY; COMPUTATIONAL GEOMETRY; COMPUTATIONAL METHODS; CONTACTS (FLUID MECHANICS); DRUG DELIVERY; FLUID MECHANICS; REACTION RATES; STAINLESS STEEL; TISSUE;

THREE DIMENSIONAL;

STAINLESS STEEL;

ARTICLE; BLOOD FLOW; BLOOD VESSEL WALL; COMPUTATIONAL FLUID DYNAMICS; CORONARY STENT; DRUG DIFFUSION; DRUG ELUTING STENT; DRUG TRANSPORT; EQUILIBRIUM CONSTANT; GEOMETRY; NONHUMAN; PHYSICAL CHEMISTRY; PREDICTION; SIMULATION; SURGICAL EQUIPMENT; THERMODYNAMICS;

EID: 79953222569     PISSN: 1869408X     EISSN: 18694098     Source Type: Journal    
DOI: 10.1007/s13239-010-0016-4     Document Type: Article

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