Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells

Diabetes

Volumn 60, Issue 4, 2011, Pages 1198-1209

  Kim, Wook ^a   Doyle, Máire E ^b   Liu, Zhuo ^a   Lao, Qizong ^a   Shin, Yu Kyong ^a   Carlson, Olga D ^a   Kim, Hee Seung ^a   Thomas, Sam ^a   Napora, Joshua K ^a   Lee, Eun Kyung ^a   Moaddel, Ruin ^a   Wang, Yan ^a   Maudsley, Stuart ^a   Martin, Bronwen ^a   Kulkarni, Rohit N ^c,d   Egan, Josephine M ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

^c JOSLIN DIABETES CENTER   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; CANNABINOID 1 RECEPTOR; GLUCOSE; INSULIN RECEPTOR; POTASSIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG INHIBITION; GLUCOSE TOLERANCE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; LASER CAPTURE MICRODISSECTION; MALE; MORPHOMETRICS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; GLUCOSE; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; HUMANS; IMMUNOPRECIPITATION; INDOLES; INSULIN-SECRETING CELLS; MALE; MICE; MICE, MUTANT STRAINS; MICE, OBESE; PIPERIDINES; POTASSIUM CHLORIDE; PROTEIN BINDING; PYRAZOLES; RECEPTOR, CANNABINOID, CB1; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

EID: 79953216705     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-1550     Document Type: Article

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