-
1
-
-
27144449009
-
Monoclonal antibody therapy of cancer
-
Adams, G.P., and L.M. Weiner. 2005. Monoclonal antibody therapy of cancer. Nature Biotechnol. 23(9):1147-1157.
-
(2005)
Nature Biotechnol
, vol.23
, Issue.9
, pp. 1147-1157
-
-
Adams, G.P.1
Weiner, L.M.2
-
2
-
-
0032212605
-
Vaccinia virus-induced apoptosis in immature B lymphocytes: Role of cellular Bcl-2
-
Baixeras, E., A. Cebrian, J.P. Albar, et al. 1998. Vaccinia virus-induced apoptosis in immature B lymphocytes: Role of cellular Bcl-2. Virus Res. 58(1-2):107-113.
-
(1998)
Virus Res
, vol.58
, Issue.1-2
, pp. 107-113
-
-
Baixeras, E.1
Cebrian, A.2
Albar, J.P.3
-
3
-
-
0029034740
-
Biologic effects of anti-interleukin-6 murine monoclonal antibody in advanced multiple myeloma
-
Bataille, R., B. Barlogie, Z.Y. Lu, et al. 1995. Biologic effects of anti-interleukin-6 murine monoclonal antibody in advanced multiple myeloma. Blood 86(2):685-691.
-
(1995)
Blood
, vol.86
, Issue.2
, pp. 685-691
-
-
Bataille, R.1
Barlogie, B.2
Lu, Z.Y.3
-
4
-
-
0033603596
-
A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies
-
de Haard, H.J., N. van Neer, A. Reurs, et al. 1999. A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies. J. Biol. Chem. 274(26):18218-18230.
-
(1999)
J. Biol. Chem
, vol.274
, Issue.26
, pp. 18218-18230
-
-
De Haard, H.J.1
Van Neer, N.2
Reurs, A.3
-
5
-
-
33845229882
-
35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer
-
Evans, E.E., A.D. Henn, A. Jonason, et al. 2006. 35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Mol. Cancer Ther. 5(11):2919-2930.
-
(2006)
Mol. Cancer Ther
, vol.5
, Issue.11
, pp. 2919-2930
-
-
Evans, E.E.1
Henn, A.D.2
Jonason, A.3
-
6
-
-
0037318058
-
Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library
-
Feldhaus, M.J., R.W. Siegel, L.K. Opresko, et al. 2003. Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library. Nature Biotechnol. 21(2):163-170.
-
(2003)
Nature Biotechnol
, vol.21
, Issue.2
, pp. 163-170
-
-
Feldhaus, M.J.1
Siegel, R.W.2
Opresko, L.K.3
-
7
-
-
0032735188
-
Modelling G-protein-coupled receptors for drug design
-
Flower, D.R. 1999. Modelling G-protein-coupled receptors for drug design. Biochim. Biophys. Acta 1422(3): 207-234.
-
(1999)
Biochim. Biophys. Acta
, vol.1422
, Issue.3
, pp. 207-234
-
-
Flower, D.R.1
-
8
-
-
33748121115
-
Interleukin-6 and chronic inflammation
-
Gabay, C. 2006. Interleukin-6 and chronic inflammation. Arthritis Res. Ther. 8(Suppl 2):S3.
-
(2006)
Arthritis Res. Ther
, vol.8
, Issue.SUPPL. 2
, pp. 3
-
-
Gabay, C.1
-
9
-
-
0033511863
-
Antibody engineering via genetic engineering of the mouse: XenoMouse strains are a vehicle for the facile generation of therapeutic human monoclonal antibodies
-
Green, L.L. 1999. Antibody engineering via genetic engineering of the mouse: XenoMouse strains are a vehicle for the facile generation of therapeutic human monoclonal antibodies. J. Immunol. Methods 231(1-2):11-23.
-
(1999)
J. Immunol. Methods
, vol.231
, Issue.1-2
, pp. 11-23
-
-
Green, L.L.1
-
10
-
-
0035869536
-
Treatment of B-lymphoproliferative disorder with a monoclonal anti-interleukin-6 antibody in 12 patients: A multicenter phase 1-2 clinical trial
-
Haddad, E., S. Paczesny, V. Leblond, et al. 2001. Treatment of B-lymphoproliferative disorder with a monoclonal anti-interleukin-6 antibody in 12 patients: A multicenter phase 1-2 clinical trial. Blood 97(6):1590-1597.
-
(2001)
Blood
, vol.97
, Issue.6
, pp. 1590-1597
-
-
Haddad, E.1
Paczesny, S.2
Leblond, V.3
-
11
-
-
27144431943
-
Selecting and screening recombinant antibody libraries
-
Hoogenboom, H.R. 2005. Selecting and screening recombinant antibody libraries. Nature Biotechnol. 23(9):1105-1116.
-
(2005)
Nature Biotechnol
, vol.23
, Issue.9
, pp. 1105-1116
-
-
Hoogenboom, H.R.1
-
12
-
-
0022558297
-
Replacing the complementarity-determining regions in a human antibody with those from a mouse
-
Jones, P.T., P.H. Dear, J. Foote, M.S. Neuberger, and G. Winter. 1986. Replacing the complementarity-determining regions in a human antibody with those from a mouse. Nature 321(6069):522-525.
-
(1986)
Nature
, vol.321
, Issue.6069
, pp. 522-525
-
-
Jones, P.T.1
Dear, P.H.2
Foote, J.3
Neuberger, M.S.4
Winter, G.5
-
13
-
-
0025990893
-
Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia
-
Klein, B., J. Wijdenes, X.G. Zhang, et al. 1991. Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia. Blood 78(5):1198-1204.
-
(1991)
Blood
, vol.78
, Issue.5
, pp. 1198-1204
-
-
Klein, B.1
Wijdenes, J.2
Zhang, X.G.3
-
14
-
-
0034635335
-
Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides
-
Knappik, A., L. Ge, A. Honegger, et al. 2000. Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides. J. Mol. Biol. 296(1):57-86.
-
(2000)
J. Mol. Biol
, vol.296
, Issue.1
, pp. 57-86
-
-
Knappik, A.1
Ge, L.2
Honegger, A.3
-
15
-
-
33748092926
-
Interleukin-6 and rheumatic diseases
-
Lipsky, P.E. 2006. Interleukin-6 and rheumatic diseases. Arthritis Res. Ther. 8(Suppl 2):S4.
-
(2006)
Arthritis Res. Ther
, vol.8
, Issue.SUPPL. 2
, pp. 4
-
-
Lipsky, P.E.1
-
16
-
-
0023611311
-
Production of a mouse-human chimeric monoclonal antibody to CD20 with potent Fc-dependent biologic activity
-
Liu, A.Y., R.R. Robinson, E.D. Murray, Jr., J.A. Ledbetter, I. Hellstrom, and K.E. Hellstrom. 1987. Production of a mouse-human chimeric monoclonal antibody to CD20 with potent Fc-dependent biologic activity. J. Immunol. 139(10):3521-3526.
-
(1987)
J. Immunol
, vol.139
, Issue.10
, pp. 3521-3526
-
-
Liu, A.Y.1
Robinson, R.R.2
Murray Jr., E.D.3
Ledbetter, J.A.4
Hellstrom, I.5
Hellstrom, K.E.6
-
17
-
-
27144532832
-
Human antibodies from transgenic animals
-
Lonberg, N. 2005. Human antibodies from transgenic animals. Nature Biotechnol. 23(9):1117-1125.
-
(2005)
Nature Biotechnol
, vol.23
, Issue.9
, pp. 1117-1125
-
-
Lonberg, N.1
-
18
-
-
0026317443
-
By-passing immunization. Human antibodies from V-gene libraries displayed on phage
-
Marks, J.D., H.R. Hoogenboom, T.P. Bonnert, J. McCafferty, A.D. Griffiths, and G. Winter. 1991. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222(3):581-597.
-
(1991)
J. Mol. Biol
, vol.222
, Issue.3
, pp. 581-597
-
-
Marks, J.D.1
Hoogenboom, H.R.2
Bonnert, T.P.3
McCafferty, J.4
Griffiths, A.D.5
Winter, G.6
-
19
-
-
34249680261
-
Isolation of engineered, full-length antibodies from libraries expressed in Escherichia coli
-
Mazor, Y., T. Van Blarcom, R. Mabry, B.L. Iverson, and G. Georgiou. 2007. Isolation of engineered, full-length antibodies from libraries expressed in Escherichia coli. Nature Biotechnol. 25(5):563-565.
-
(2007)
Nature Biotechnol
, vol.25
, Issue.5
, pp. 563-565
-
-
Mazor, Y.1
Van Blarcom, T.2
Mabry, R.3
Iverson, B.L.4
Georgiou, G.5
-
20
-
-
0031876578
-
An efficient route to human bispecific IgG
-
Merchant, A.M., Z. Zhu, J.Q. Yuan, et al. 1998. An efficient route to human bispecific IgG. Nature Biotechnol. 16(7):677-681.
-
(1998)
Nature Biotechnol
, vol.16
, Issue.7
, pp. 677-681
-
-
Merchant, A.M.1
Zhu, Z.2
Yuan, J.Q.3
-
21
-
-
0031585554
-
Construction and characterization of vaccinia direct ligation vectors
-
Merchlinsky, M., D. Eckert, E. Smith, and M. Zauderer. 1997. Construction and characterization of vaccinia direct ligation vectors. Virology 238(2):444-451.
-
(1997)
Virology
, vol.238
, Issue.2
, pp. 444-451
-
-
Merchlinsky, M.1
Eckert, D.2
Smith, E.3
Zauderer, M.4
-
22
-
-
0021716682
-
Chimeric human antibody molecules: Mouse antigen-binding domains with human constant region domains
-
Morrison, S.L., M.J. Johnson, L.A. Herzenberg, and V.T. Oi. 1984. Chimeric human antibody molecules: Mouse antigen-binding domains with human constant region domains. Proc. Natl. Acad. Sci. USA 81(21):6851-6855.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, Issue.21
, pp. 6851-6855
-
-
Morrison, S.L.1
Johnson, M.J.2
Herzenberg, L.A.3
Oi, V.T.4
-
23
-
-
0025815449
-
Vaccinia virus: A tool for research and vaccine development
-
Moss, B. 1991. Vaccinia virus: A tool for research and vaccine development. Science 252(5013):1662-1667.
-
(1991)
Science
, vol.252
, Issue.5013
, pp. 1662-1667
-
-
Moss, B.1
-
24
-
-
4043111826
-
G protein-coupled receptors in drug discovery
-
Nambi, P., and N. Aiyar. 2003. G protein-coupled receptors in drug discovery. Assay Drug Dev. Technol. 1(2):305-310.
-
(2003)
Assay Drug Dev. Technol
, vol.1
, Issue.2
, pp. 305-310
-
-
Nambi, P.1
Aiyar, N.2
-
25
-
-
0028006072
-
Antibody fragments from a "single pot" phage display library as immunochemical reagents
-
Nissim, A., H.R. Hoogenboom, I.M. Tomlinson, et al. 1994. Antibody fragments from a "single pot" phage display library as immunochemical reagents. EMBO J. 13(3):692-698.
-
(1994)
EMBO J
, vol.13
, Issue.3
, pp. 692-698
-
-
Nissim, A.1
Hoogenboom, H.R.2
Tomlinson, I.M.3
-
26
-
-
17644406997
-
From rodent reagents to human therapeutics using antibody guided selection
-
Osbourn, J., M. Groves, and T. Vaughan. 2005. From rodent reagents to human therapeutics using antibody guided selection. Methods 36(1):61-68.
-
(2005)
Methods
, vol.36
, Issue.1
, pp. 61-68
-
-
Osbourn, J.1
Groves, M.2
Vaughan, T.3
-
27
-
-
0024815233
-
A humanized antibody that binds to the interleukin 2 receptor
-
Queen, C., W.P. Schneider, H.E. Selick, et al. 1989. A humanized antibody that binds to the interleukin 2 receptor. Proc. Natl. Acad. Sci. USA 86(24):10029-10033.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, Issue.24
, pp. 10029-10033
-
-
Queen, C.1
Schneider, W.P.2
Selick, H.E.3
-
28
-
-
0029997084
-
Recombinant protein synthesis in Chinese hamster ovary cells using a vaccinia virus/bacteriophage T7 hybrid expression system
-
Ramsey-Ewing, A., and B. Moss. 1996. Recombinant protein synthesis in Chinese hamster ovary cells using a vaccinia virus/bacteriophage T7 hybrid expression system. J. Biol. Chem. 271(28):16962-16966.
-
(1996)
J. Biol. Chem
, vol.271
, Issue.28
, pp. 16962-16966
-
-
Ramsey-Ewing, A.1
Moss, B.2
-
29
-
-
27144457667
-
Monoclonal antibody successes in the clinic
-
Reichert, J.M., C.J. Rosensweig, L.B. Faden, and M.C. Dewitz. 2005. Monoclonal antibody successes in the clinic. Nature Biotechnol. 23(9):1073-1078.
-
(2005)
Nature Biotechnol
, vol.23
, Issue.9
, pp. 1073-1078
-
-
Reichert, J.M.1
Rosensweig, C.J.2
Faden, L.B.3
Dewitz, M.C.4
-
30
-
-
27744520953
-
2 of melphalan in multiple myeloma: Results of a pilot study including biological aspects
-
2 of melphalan in multiple myeloma: Results of a pilot study including biological aspects. Bone Marrow Transplant. 36(9):771-779.
-
(2005)
Bone Marrow Transplant
, vol.36
, Issue.9
, pp. 771-779
-
-
Rossi, J.F.1
Fegueux, N.2
Lu, Z.Y.3
-
31
-
-
0026472482
-
Construction of chimeric vaccinia viruses by molecular cloning and packaging
-
Scheiflinger, F., F. Dorner, and F.G. Falkner. 1992. Construction of chimeric vaccinia viruses by molecular cloning and packaging. Proc. Natl. Acad. Sci. USA 89(21):9977-9981.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, Issue.21
, pp. 9977-9981
-
-
Scheiflinger, F.1
Dorner, F.2
Falkner, F.G.3
-
32
-
-
13144261717
-
Efficient construction of a large nonimmune phage antibody library: The production of high-affinity human single-chain antibodies to protein antigens
-
Sheets, M.D., P. Amersdorfer, R. Finnern, et al. 1998. Efficient construction of a large nonimmune phage antibody library: The production of high-affinity human single-chain antibodies to protein antigens. Proc. Natl. Acad. Sci. USA 95(11):6157-6162.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.11
, pp. 6157-6162
-
-
Sheets, M.D.1
Amersdorfer, P.2
Finnern, R.3
-
33
-
-
0034890610
-
Lethality-based selection of recombinant genes in mammalian cells: Application to identifying tumor antigens
-
Smith, E.S., A. Mandokhot, E.E. Evans, et al. 2001. Lethality-based selection of recombinant genes in mammalian cells: Application to identifying tumor antigens. Nature Med. 7(8):967-972.
-
(2001)
Nature Med
, vol.7
, Issue.8
, pp. 967-972
-
-
Smith, E.S.1
Mandokhot, A.2
Evans, E.E.3
-
34
-
-
4043067701
-
Construction of cDNA libraries in vaccinia virus
-
Smith, E.S., S. Shi, and M. Zauderer. 2004. Construction of cDNA libraries in vaccinia virus. Methods Mol. Biol. 269:65-76.
-
(2004)
Methods Mol. Biol
, vol.269
, pp. 65-76
-
-
Smith, E.S.1
Shi, S.2
Zauderer, M.3
-
35
-
-
33748110308
-
Interleukin-6: A new therapeutic target
-
Smolen, J.S., and R.N. Maini. 2006. Interleukin-6: A new therapeutic target. Arthritis Res. Ther. 8(Suppl 2):S5.
-
(2006)
Arthritis Res. Ther
, vol.8
, Issue.SUPPL. 2
, pp. 5
-
-
Smolen, J.S.1
Maini, R.N.2
-
36
-
-
0027443053
-
Fowlpox virus host range restriction: gene expression, DNA replication, and morphogenesis in nonpermissive mammalian cells
-
Somogyi, P., J. Frazier, and M.A. Skinner. 1993. Fowlpox virus host range restriction: gene expression, DNA replication, and morphogenesis in nonpermissive mammalian cells. Virology 197(1):439-444.
-
(1993)
Virology
, vol.197
, Issue.1
, pp. 439-444
-
-
Somogyi, P.1
Frazier, J.2
Skinner, M.A.3
-
37
-
-
0029655747
-
Gene expression and cytopathic effect of vaccinia virus inactivated by psoralen and long-wave UV light
-
Tsung, K., J.H. Yim, W. Marti, R.M. Buller, and J.A. Norton. 1996. Gene expression and cytopathic effect of vaccinia virus inactivated by psoralen and long-wave UV light. J. Virol. 70(1):165-171.
-
(1996)
J. Virol
, vol.70
, Issue.1
, pp. 165-171
-
-
Tsung, K.1
Yim, J.H.2
Marti, W.3
Buller, R.M.4
Norton, J.A.5
-
38
-
-
84941626516
-
Humanization of monoclonal antibodies
-
In: T. Honjo, F.W. Alt, and M. Neuberger (eds),, Academic press.
-
Tsurushita, N., and M. Vasquez. 2003. Humanization of monoclonal antibodies. In: T. Honjo, F.W. Alt, and M. Neuberger (eds), Molecular Biology of B Cells, Academic press. 533-546.
-
(2003)
Molecular Biology of B Cells
, pp. 533-546
-
-
Tsurushita, N.1
Vasquez, M.2
-
39
-
-
0037494981
-
Affinity maturation of Fab antibody fragments by fluorescent-activated cell sorting of yeast-displayed libraries
-
Van den Buecken, T., H. Pieters, M. Steukers, et al. 2003. Affinity maturation of Fab antibody fragments by fluorescent-activated cell sorting of yeast-displayed libraries. FEBS Lett. 546(2-3):288-294.
-
(2003)
FEBS Lett
, vol.546
, Issue.2-3
, pp. 288-294
-
-
Van Den Buecken, T.1
Pieters, H.2
Steukers, M.3
-
40
-
-
20944442617
-
Depletion of B cells by a humanized anti-CD20 antibody PR070769 in Macaca fascicularis
-
Vugmeyster, Y., J. Beyer, K. Howell, et al. 2005. Depletion of B cells by a humanized anti-CD20 antibody PR070769 in Macaca fascicularis. J. Immunother. 28(3):212-219.
-
(2005)
J. Immunother
, vol.28
, Issue.3
, pp. 212-219
-
-
Vugmeyster, Y.1
Beyer, J.2
Howell, K.3
-
41
-
-
0025942846
-
Humanrecombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies
-
Wijdenes, J., C. Clement, B. Klein, et al. 1991. Humanrecombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies. Mol. Immunol. 28(11):1183-1192.
-
(1991)
Mol. Immunol
, vol.28
, Issue.11
, pp. 1183-1192
-
-
Wijdenes, J.1
Clement, C.2
Klein, B.3
|