Murine interleukin-3: Structure, dynamics, and conformational heterogeneity in solution

Biochemistry

Volumn 50, Issue 13, 2011, Pages 2464-2477

  Yao, Shenggen ^a,b   Young, Ian G ^c   Norton, Raymond S ^a,d   Murphy, James M ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c Australian National University   (Australia)

^d MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGIC INFLAMMATION; CONFORMATIONAL EXCHANGE; CONFORMATIONAL HETEROGENEITY; CYTOKINES; HELICAL BUNDLE; HIGHER TEMPERATURES; HYDROPHOBIC RESIDUES; IMMUNE RESPONSE; INTERLEUKIN-3; ISOFORMS; LINE BROADENING; NATURALLY OCCURRING; NMR SPECTRUM; OLIGOMERIC STATE; RELAXATION DISPERSION; RELAXATION PARAMETER; SOLUTION CONDITIONS; SOLUTION PROPERTY; STRUCTURAL STUDIES; T CELLS; TEMPERATURE DEPENDENCE; TEMPERATURE-DEPENDENT CHANGES; THREE-DIMENSIONAL STRUCTURE;

AMIDES; COMPLEXATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERS;

CONFORMATIONS;

BETA INTERLEUKIN 3 RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 3 RECEPTOR; INTERLEUKIN 5; OLIGOMER; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MUTAGENESIS; HUMAN; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN POLYMORPHISM; PROTEIN STRUCTURE; TEMPERATURE DEPENDENCE;

ANIMALS; HYDROGEN-ION CONCENTRATION; INTERLEUKIN-3; MICE; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT PROTEINS; SOLUBILITY; TEMPERATURE;

MURINAE;

EID: 79953211861     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101810f     Document Type: Article

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