Concise synthesis of 5-methoxy-6-hydroxy-2-methylchromone-7-O- and 5-hydroxy-2-methylchromone-7-O-rutinosides. Investigation of their cytotoxic activities against several human tumor cell lines

Journal of Organic Chemistry

Volumn 76, Issue 7, 2011, Pages 2265-2268

  Wu, Baolin ^a   Zhang, Wenpeng ^a   Li, Zhonghua ^b   Gu, Li ^a,c   Wang, Xin ^b   Wang, Peng George ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b NANKAI UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANOMERICS; BIOLOGICAL ACTIVITIES; CONCISE SYNTHESIS; CYTOTOXIC ACTIVITIES; GLYCOSIDATIONS; GLYCOSIDIC BOND; HUMAN TUMOR CELLS; IN-VITRO; LEAVING GROUPS; METHOXY; OH GROUP; PHASE TRANSFER; RUTINOSIDES; SYNTHESIS FEATURES; SYNTHETIC PRECURSORS;

CELL CULTURE; CYTOTOXICITY; SUGARS;

TUMORS;

2 METHYLCHROMONE AGLYCON; 5 HYDROXY 2 METHYLCHROMONE 7 O RUTINOSIDE; 5 METHOXY 6 HYDROXY 2 METHYLCHROMONE 7 O RUTINOSIDE; AGLYCONE; ANTINEOPLASTIC AGENT; DOXORUBICIN; SUGAR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CATALYSIS; CELL GROWTH; CELL STRAIN K 562; CELL STRAIN MCF 7; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; GLYCOSIDATION; GLYCOSYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHROMONES; FLAVONOIDS; GLYCOSIDES; GLYCOSYLATION; HUMANS; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PHENOLS;

EID: 79953207676     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo102325s     Document Type: Article

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