Studying competitive lithiations at alpha-, ortho-, and benzylic positions in various N-protected aniline derivatives

Tetrahedron

Volumn 67, Issue 16, 2011, Pages 2895-2904

  Schmid, Martin ^a   Waldner, Birgit ^a   Schnürch, Michael ^a   Mihovilovic, Marko D ^a   Stanetty, Peter ^a  

^a VIENNA UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

Directed metalation; Directing metalation group; Ortho lithiation; Protecting group; Regioselectivity

Indexed keywords

1,1 DIMETHYETHYL N METHYL N [2 (METHYLTHIO)PHENYL]CARBAMATE; 1,1 DIMETHYLETHYL N (2 ETHYLPHENYL) N [(METHYLTHIO)METHYL]CARBAMATE; 1,1 DIMETHYLETHYL N (2 ETHYLPHENYL) N METHYL CARBAMATE; 1,1 DIMETHYLETHYL N (2 METHYLPHENYL) N [(TRIMETHYLSILYL)METHYL]CARBAMATE; 1,1 DIMETHYLETHYL N ETHYL [2 ETHYL 6 (METHYLTHIO) PHENYL]CARBAMATE; 1,1 DIMETHYLETHYL N ETHYL N (2 ETHYLPHENYL)CARBAMATE; 1,1 DIMETHYLETHYL N ETHYL N (2 METHYLPHENYL)CARBAMATE; 1,1 DIMETHYLETHYL N ETHYL N [2 (METHYLTHIO)PHENYL]CARBAMATE; 1,1 DIMETHYLETHYL N METHYL N [2 (METHYLETHYL) 6 (METHYLTHIO)PHENYL]CARBAMATE; 1,1 DIMETHYLETHYL N METHYL N [2 [(METHYLTHIO)METHYL]PHENYL] CARBAMATE; 1,1 DIMETHYLETHYL N METHYL N [2 [(METHYLTHIO)METHYL]PHENYL]CARBAMATE; 1,1 DIMETHYLETHYL N METHYL N [2 [(TRIMETHYLSILYL)METHYL]PHENYL]CARBAMATE; 2 (1,1 DIMETHYLETHYL) 1 ETHYLINDOLE; 2,2 DIMETHYL N (2 METHYLPHENYL) N [(METHYLTHIO)METHYL] PROPANAMIDE; 2,2 DIMETHYL N (2,2 DIMETHYLAMINOCARBONYLMETHYLEN) N (2 METHYLPHENYL)PROPANAMIDE; 2,2 DIMETHYL N [2 (1 METHYLETHYL) 6 (METHYLTHIO)PHENYL] PROPANAMIDE; 2,2 DIMETHYL N [2 [(1 METHYLTHIO)ETHYL]PHENYL] PROPANAMIDE; 3 (3 ETHYL 2 (ETHYLAMINO)PHENYL) 2,2,4,4 TETRAMETHYLPENTAN 3 OL; ALKYL GROUP; ANILINE DERIVATIVE; METHYL GROUP; N ETHYL N (2 ETHYLPHENYL) 2,2 DIMETHYLPROPANAMIDE; N,2,2 TRIMETHYL (2 METHYLPHENYL)PROPANAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; HIGH TEMPERATURE; LITHIATION; PRIORITY JOURNAL; STEREOCHEMISTRY; SUBSTITUTION REACTION; SYNTHESIS;

EID: 79953207630     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2011.02.056     Document Type: Article

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