메뉴 건너뛰기




Volumn 180, Issue , 2011, Pages 238-247

Saffron extract and trans-crocetin inhibit glutamatergic synaptic transmission in rat cortical brain slices

Author keywords

Glutamate; Kainate; NMDA; Saffron; Synaptic transmission; Trans crocetin

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CROCETIN; GLUTAMIC ACID; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; PLANT EXTRACT; SAFFRON EXTRACT; UNCLASSIFIED DRUG;

EID: 79953198908     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.02.037     Document Type: Article
Times cited : (76)

References (33)
  • 3
    • 25444434647 scopus 로고    scopus 로고
    • Orally administered crocetin and crocins are absorbed into blood plasma as crocetin and its glucuronide conjugates in mice
    • Asai A., Nakano T., Takahashi M., Nagao A. Orally administered crocetin and crocins are absorbed into blood plasma as crocetin and its glucuronide conjugates in mice. J Agric Food Chem 2005, 53:7302-7306.
    • (2005) J Agric Food Chem , vol.53 , pp. 7302-7306
    • Asai, A.1    Nakano, T.2    Takahashi, M.3    Nagao, A.4
  • 4
    • 0033758890 scopus 로고    scopus 로고
    • Adenosine A1 and A3 receptors mediate inhibition of synaptic transmission in rat cortical neurones
    • Brand A., Vissiennon Z., Eschke D., Nieber K. Adenosine A1 and A3 receptors mediate inhibition of synaptic transmission in rat cortical neurones. Neuropharmacology 2001, 40:85-95.
    • (2001) Neuropharmacology , vol.40 , pp. 85-95
    • Brand, A.1    Vissiennon, Z.2    Eschke, D.3    Nieber, K.4
  • 5
    • 0023796923 scopus 로고
    • Synaptic potentials in rat locus coeruleus neurones
    • Cherubini E., North R.A., Williams J.T. Synaptic potentials in rat locus coeruleus neurones. J Physiol 1988, 406:431-442.
    • (1988) J Physiol , vol.406 , pp. 431-442
    • Cherubini, E.1    North, R.A.2    Williams, J.T.3
  • 6
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1988, 1:623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 7
    • 0038265892 scopus 로고    scopus 로고
    • Activation of A(3) receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons
    • Hentschel S., Lewerenz A., Nieber K. Activation of A(3) receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons. Restor Neurol Neurosci 2003, 21(1-2):55-63.
    • (2003) Restor Neurol Neurosci , vol.21 , Issue.1-2 , pp. 55-63
    • Hentschel, S.1    Lewerenz, A.2    Nieber, K.3
  • 9
    • 27444447828 scopus 로고    scopus 로고
    • Anticonvulsant evaluation of safranal and crocin from Crocus sativus in mice
    • Hosseinzadeh H., Talebzadeh F. Anticonvulsant evaluation of safranal and crocin from Crocus sativus in mice. Fitoterapia 2005, 76:722-724.
    • (2005) Fitoterapia , vol.76 , pp. 722-724
    • Hosseinzadeh, H.1    Talebzadeh, F.2
  • 10
    • 54249101071 scopus 로고    scopus 로고
    • Effect of safranal on extracellular hippocampal levels of glutamate and aspartate during kainic acid treatment in anaesthetized rats
    • Hosseinzadeh H., Sadeghnia H.R., Rahimi A. Effect of safranal on extracellular hippocampal levels of glutamate and aspartate during kainic acid treatment in anaesthetized rats. Planta Med 2008, 74:1441-1445.
    • (2008) Planta Med , vol.74 , pp. 1441-1445
    • Hosseinzadeh, H.1    Sadeghnia, H.R.2    Rahimi, A.3
  • 11
    • 27444442382 scopus 로고    scopus 로고
    • Safranal, a constituent of Crocus sativus (saffron), attenuated cerebral ischemia induced oxidative damage in rat hippocampus
    • Hosseinzadeh H., Sadeghnia H.R. Safranal, a constituent of Crocus sativus (saffron), attenuated cerebral ischemia induced oxidative damage in rat hippocampus. J Pharm Pharm Sci 2005, 8(3):394-399.
    • (2005) J Pharm Pharm Sci , vol.8 , Issue.3 , pp. 394-399
    • Hosseinzadeh, H.1    Sadeghnia, H.R.2
  • 12
    • 33847752592 scopus 로고    scopus 로고
    • Protective effect of safranal on pentylenetetrazol-induced seizures in the rat: involvement of GABAergic and opioids system
    • Hosseinzadeh H., Sadeghnia H.R. Protective effect of safranal on pentylenetetrazol-induced seizures in the rat: involvement of GABAergic and opioids system. Phytomedicine 2007, 14:256-262.
    • (2007) Phytomedicine , vol.14 , pp. 256-262
    • Hosseinzadeh, H.1    Sadeghnia, H.R.2
  • 13
    • 0036830627 scopus 로고    scopus 로고
    • NMDA receptor pathways as drug targets
    • Kemp J.A., McKernan R.M. NMDA receptor pathways as drug targets. Nat Neurosci 2002, 5(Suppl):1039-1042.
    • (2002) Nat Neurosci , vol.5 , Issue.SUPPL. , pp. 1039-1042
    • Kemp, J.A.1    McKernan, R.M.2
  • 14
    • 33845671730 scopus 로고    scopus 로고
    • Potential medicinal plants for CNS disorders: an overview
    • Kumar V. Potential medicinal plants for CNS disorders: an overview. Phytother Res 2006, 20:1023-1035.
    • (2006) Phytother Res , vol.20 , pp. 1023-1035
    • Kumar, V.1
  • 15
    • 45849129861 scopus 로고    scopus 로고
    • Quality and functionality of saffron: quality control, species assortment and affinity of extract and isolated saffron compounds to NMDA and σ σ1 (sigma-1) receptors
    • Lechtenberg M., Schepmann D., Niehues M., Hellenbrand N., Wunsch B., Hensel A. Quality and functionality of saffron: quality control, species assortment and affinity of extract and isolated saffron compounds to NMDA and σ σ1 (sigma-1) receptors. Planta Med 2008, 74:764-772.
    • (2008) Planta Med , vol.74 , pp. 764-772
    • Lechtenberg, M.1    Schepmann, D.2    Niehues, M.3    Hellenbrand, N.4    Wunsch, B.5    Hensel, A.6
  • 16
    • 0037712610 scopus 로고    scopus 로고
    • A(3) receptors in cortical neurons: pharmacological aspects and neuroprotection during hypoxia
    • Lewerenz A., Hentschel S., Vissiennon Z., Michael S., Nieber K. A(3) receptors in cortical neurons: pharmacological aspects and neuroprotection during hypoxia. Drug Dev Res 2003, 58(4):420-427.
    • (2003) Drug Dev Res , vol.58 , Issue.4 , pp. 420-427
    • Lewerenz, A.1    Hentschel, S.2    Vissiennon, Z.3    Michael, S.4    Nieber, K.5
  • 17
    • 33845773372 scopus 로고    scopus 로고
    • The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus
    • Martina M., Turcotte M.E., Halman S., Bergeron R. The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus. J Physiol 2007, 578(1):143-157.
    • (2007) J Physiol , vol.578 , Issue.1 , pp. 143-157
    • Martina, M.1    Turcotte, M.E.2    Halman, S.3    Bergeron, R.4
  • 18
    • 56249097197 scopus 로고    scopus 로고
    • Stimulatory effect of Crocus sativus (saffron) on β2-adrenoceptors of guinea pig tracheal chains
    • Nemati H., Boskabady M.H., Ahmadzadef Vostakolaei H. Stimulatory effect of Crocus sativus (saffron) on β2-adrenoceptors of guinea pig tracheal chains. Phytomedicine 2008, 15:1038-1045.
    • (2008) Phytomedicine , vol.15 , pp. 1038-1045
    • Nemati, H.1    Boskabady, M.H.2    Ahmadzadef Vostakolaei, H.3
  • 19
    • 0030921149 scopus 로고    scopus 로고
    • Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat
    • Nieber K., Poelchen W., Illes P. Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat. Br J Pharmacol 1997, 122(3):423-430.
    • (1997) Br J Pharmacol , vol.122 , Issue.3 , pp. 423-430
    • Nieber, K.1    Poelchen, W.2    Illes, P.3
  • 20
    • 0345304238 scopus 로고    scopus 로고
    • Crocin prevents the death of PC-12 cells through sphingomyelinase-ceramide signalling by increasing glutathione synthesis
    • Ochiai T., Soeda S., Ohno S., Tanaka H., Shoyama Y., Shimeno H. Crocin prevents the death of PC-12 cells through sphingomyelinase-ceramide signalling by increasing glutathione synthesis. Neurochem Int 2004, 44:321-330.
    • (2004) Neurochem Int , vol.44 , pp. 321-330
    • Ochiai, T.1    Soeda, S.2    Ohno, S.3    Tanaka, H.4    Shoyama, Y.5    Shimeno, H.6
  • 22
    • 0014682523 scopus 로고
    • Brain lesions in an infant rhesus monkey treated with monosodium glutamate
    • Olney J.W., Sharpe L.G. Brain lesions in an infant rhesus monkey treated with monosodium glutamate. Science 1969, 166:386-388.
    • (1969) Science , vol.166 , pp. 386-388
    • Olney, J.W.1    Sharpe, L.G.2
  • 23
    • 0025358559 scopus 로고
    • Enhancement of current induced by superfusion of GABA in locus coeruleus neurons by pentobarbital, but not ethanol
    • Osmanovic S.S., Shefner S.A. Enhancement of current induced by superfusion of GABA in locus coeruleus neurons by pentobarbital, but not ethanol. Brain Res 1990, 517:324-329.
    • (1990) Brain Res , vol.517 , pp. 324-329
    • Osmanovic, S.S.1    Shefner, S.A.2
  • 25
    • 0032467053 scopus 로고    scopus 로고
    • Glutamate in CNS disorders as a target for drug development: an update
    • Parsons C.G., Danysz W., Quack G. Glutamate in CNS disorders as a target for drug development: an update. Drug News Perspect 1998, 11:523-569.
    • (1998) Drug News Perspect , vol.11 , pp. 523-569
    • Parsons, C.G.1    Danysz, W.2    Quack, G.3
  • 26
    • 58149119700 scopus 로고    scopus 로고
    • Antiabsence effects of safranal in acute experimental seizure models: EEG and autoradiography
    • Sadeghnia H.R., Cortez M.A., Liu D., Hosseinzadeh H., Snead O.C. Antiabsence effects of safranal in acute experimental seizure models: EEG and autoradiography. J Pharm Pharm Sci 2008, 11(3):1-14.
    • (2008) J Pharm Pharm Sci , vol.11 , Issue.3 , pp. 1-14
    • Sadeghnia, H.R.1    Cortez, M.A.2    Liu, D.3    Hosseinzadeh, H.4    Snead, O.C.5
  • 27
    • 33745826332 scopus 로고    scopus 로고
    • Effect of saffron (Crocus sativus) on neurobehavioral and neurochemical changes in cerebral ischemia in rats
    • Saleem S., Ahmad M., Ahmad A.S., Yousuf S., Ansari M.A., Khan M.B., Ishrat T., Islam F. Effect of saffron (Crocus sativus) on neurobehavioral and neurochemical changes in cerebral ischemia in rats. J Med Food 2006, 9(2):246-253.
    • (2006) J Med Food , vol.9 , Issue.2 , pp. 246-253
    • Saleem, S.1    Ahmad, M.2    Ahmad, A.S.3    Yousuf, S.4    Ansari, M.A.5    Khan, M.B.6    Ishrat, T.7    Islam, F.8
  • 28
    • 34548445132 scopus 로고    scopus 로고
    • Saffron in phytotherapy: pharamcology and clinical uses
    • Schmidt M., Betti G., Hensel A. Saffron in phytotherapy: pharamcology and clinical uses. Wien Med Wochenschr 2007, 157(13-14):315-319.
    • (2007) Wien Med Wochenschr , vol.157 , Issue.13-14 , pp. 315-319
    • Schmidt, M.1    Betti, G.2    Hensel, A.3
  • 29
    • 35348914265 scopus 로고    scopus 로고
    • Modulation of postsynaptic potentials in rat cortical neurons by valerian extracts macerated with different alcohols: involvement of adenosine A(1)- and GABA(A)-receptors
    • Sichardt K., Vissiennon Z., Koetter U., Brattström A., Nieber K. Modulation of postsynaptic potentials in rat cortical neurons by valerian extracts macerated with different alcohols: involvement of adenosine A(1)- and GABA(A)-receptors. Phytother Res 2007, 21(10):932-937.
    • (2007) Phytother Res , vol.21 , Issue.10 , pp. 932-937
    • Sichardt, K.1    Vissiennon, Z.2    Koetter, U.3    Brattström, A.4    Nieber, K.5
  • 31
    • 35948947269 scopus 로고    scopus 로고
    • On the hypes and falls in neuroprotection: targeting the NMDA receptor
    • Villmann C., Becker C.M. On the hypes and falls in neuroprotection: targeting the NMDA receptor. Neuroscientist 2007, 13(6):594-615.
    • (2007) Neuroscientist , vol.13 , Issue.6 , pp. 594-615
    • Villmann, C.1    Becker, C.M.2
  • 32
    • 33745683977 scopus 로고    scopus 로고
    • Valerian extract Ze 911 inhibits postsynaptic potentials by activation of adenosine A1 receptors in rat cortical neurons
    • Vissiennon Z., Sichardt K., Koetter U., Brattström A., Nieber K. Valerian extract Ze 911 inhibits postsynaptic potentials by activation of adenosine A1 receptors in rat cortical neurons. Planta Med 2006, 72(7):579-583.
    • (2006) Planta Med , vol.72 , Issue.7 , pp. 579-583
    • Vissiennon, Z.1    Sichardt, K.2    Koetter, U.3    Brattström, A.4    Nieber, K.5
  • 33
    • 33847190347 scopus 로고    scopus 로고
    • Effects of crocin on reperfusion-induced oxidative/nitrative injury to cerebral microvessels after global cerebral ischemia
    • Zheng Y.Q., Liu J.X., Wang J.N., Xu L. Effects of crocin on reperfusion-induced oxidative/nitrative injury to cerebral microvessels after global cerebral ischemia. Brain Res 2007, 1138:86-94.
    • (2007) Brain Res , vol.1138 , pp. 86-94
    • Zheng, Y.Q.1    Liu, J.X.2    Wang, J.N.3    Xu, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.