Metal-free halonium mediated acetate shifts of ynamides to access α-halo acrylamides/acrylimides

Organic Letters

Volumn 13, Issue 7, 2011, Pages 1750-1753

  Kramer, Søren ^a   Friis, Stig D ^a   Xin, Zhuo ^a   Odabachian, Yann ^b   Skrydstrup, Troels ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b LABORATOIRE DE SYNTHÈSE ORGANIQUE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79953186956     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol200269h     Document Type: Article

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50. N -Fluorobenzenesulfonimide.
51. See Supporting Information for the optimization.
52. The Z -configuration was confirmed by the proton-fluorine coupling constant.
53. A concerted [3,3]-rearrangement of 5 would also explain the stereochemical outcome.