DNA methylation in metabolic disorders

American Journal of Clinical Nutrition

Volumn 93, Issue 4, 2011, Pages

  Barres, Romain ^a   Zierath, Juleen R ^b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CONFERENCE PAPER; DIABETES MELLITUS; DIET; DNA METHYLATION; DNA MODIFICATION; ENVIRONMENTAL FACTOR; EXERCISE; GENE CONTROL; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; HUMAN; LIFESTYLE; METABOLIC DISORDER; NONHUMAN; OBESITY;

DIET; DNA METHYLATION; ENVIRONMENT; EPIGENESIS, GENETIC; EXERCISE; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; METABOLIC DISEASES;

EID: 79953171491     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.110.001933     Document Type: Conference Paper

References (40)

1. Rein T, DePamphilis ML, Zorbas H. Identifying 5-methylcytosine and related modifications in DNA genomes. Nucleic Acids Res 1998;26: 2255-64. (Pubitemid 28297322)
2. Bird A. Perceptions of epigenetics. Nature 2007;447:396-8. (Pubitemid 46816744)
3. Barres R, Osler ME, Yan J, et al. Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. Cell Metab 2009;10:189-98.
4. Bjornsson HT, Sigurdsson MI, Fallin MD, et al. Intra-individual change over time in DNA methylation with familial clustering. JAMA 2008; 299:2877-83. (Pubitemid 351930887)
5. Jones PA. DNA methylation and cancer. Cancer Res 1986;46:461-6. (Pubitemid 16145385)
6. Ling C, Poulsen P, Simonsson S, et al. Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle. J Clin Invest 2007;117:3427-35. (Pubitemid 350096998)
7. Diamond J. The double puzzle of diabetes. Nature 2003;423:599-602. (Pubitemid 36713209)
8. Zimmet P, Alberti KGMM, Shaw J. Global and societal implications of the diabetes epidemic. Nature 2001;414:782-7. (Pubitemid 34000780)
9. Gaster M, Petersen I, Hojlund K, Poulsen P, Beck-Nielsen H. The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity. Diabetes 2002;51:921-7. (Pubitemid 34438332)
10. Henry RR, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Park KS, Nikoulina SE. Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms. J Clin Invest 1996;98:1231-6. (Pubitemid 26299936)
11. Staiger H, Stefan N, Machicao F, Fritsche A, Haring HU. PPARGC1A mRNA levels of in vitro differentiated human skeletal muscle cells are negatively associated with the plasma oleate concentrations of the donors. Diabetologia 2006;49:212-4. (Pubitemid 43151635)
12. Fraga MF, Ballestar E, Paz MF, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005;102:10604-9. (Pubitemid 41061601)
13. Sutherland JE, Costa M. Epigenetics and the environment. Ann N Y Acad Sci 2003;983:151-60. (Pubitemid 36399328)
14. Morgan HD, Sutherland HG, Martin DI, Whitelaw E. Epigenetic inheritance at the agouti locus in the mouse. Nat Genet 1999;23:314-8. (Pubitemid 29526429)
15. Anway MD, Cupp AS, Uzumcu M, Skinner MK. Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 2005;308:1466-9. (Pubitemid 40791300)
16. Weaver IC, Cervoni N, Champagne FA, et al. Epigenetic programming by maternal behavior. Nat Neurosci 2004;7:847-54. (Pubitemid 38989508)
17. Waterland RA. Do maternal methyl supplements in mice affect DNA methylation of offspring? J Nutr 2003;133:238, author reply 239.
18. Ghoshal K, Li X, Datta J, et al. A folate- and methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats. J Nutr 2006;136:1522-7. (Pubitemid 43765356)
19. Pogribny IP, Ross SA, Wise C, et al. Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency. Mutat Res 2006;593:80-7. (Pubitemid 43113364)
20. Reid G, Metivier R, Lin CY, et al. Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A. Oncogene 2005;24:4894-907. (Pubitemid 41129094)
21. Kangaspeska S, Stride B, Metivier R, et al. Transient cyclical methylation of promoter DNA. Nature 2008;452:112-5. (Pubitemid 351355094)
22. Metivier R, Gallais R, Tiffoche C, et al. Cyclical DNA methylation of a transcriptionally active promoter. Nature 2008;452:45-50. (Pubitemid 351355084)
23. de Haan JB, Gevers W, Parker MI. Effects of sodium butyrate on the synthesis and methylation of DNA in normal cells and their transformed counterparts. Cancer Res 1986;46:713-6. (Pubitemid 16145427)
24. Meyer P, Niedenhof I, ten Lohuis M. Evidence for cytosine methylation of non-symmetrical sequences in transgenic Petunia hybrida. EMBO J 1994;13:2084-8.
25. Grandjean V, Yaman R, Cuzin F, Rassoulzadegan M. Inheritance of an epigenetic mark: the CpG DNA methyltransferase 1 is required for de novo establishment of a complex pattern of non-CpG methylation. PLoS ONE 2007;2:e1136.
26. Ramsahoye BH, Biniszkiewicz D, Lyko F, Clark V, Bird AP, Jaenisch R. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci USA 2000;97:5237-42. (Pubitemid 30313702)
27. Tasheva ES, Roufa DJ. Densely methylated DNA islands in mammalian chromosomal replication origins. Mol Cell Biol 1994;14:5636-44. (Pubitemid 24264391)
28. Rein T, Zorbas H, DePamphilis ML. Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides. Mol Cell Biol 1997;17:416-26. (Pubitemid 26425631)
29. Woodcock DM, Crowther PJ, Diver WP. The majority of methylated deoxycytidines in human DNA are not in the CpG dinucleotide. Biochem Biophys Res Commun 1987;145:888-94.
30. Lister R, Pelizzola M, Dowen RH, et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009; 462:315-22.
31. Ronn T, Poulsen P, Hansson O, et al. Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle. Diabetologia 2008;51:1159-68.
32. Kuroda A, Rauch TA, Todorov I, et al. Insulin gene expression is regulated by DNA methylation. PLoS ONE 2009;4:e6953.
33. Yokomori N, Tawata M, Onaya T. DNA demethylation during the differentiation of 3T3-L1 cells affects the expression of the mouse GLUT4 gene. Diabetes 1999;48:685-90. (Pubitemid 29153065)
34. Fujiki K, Kano F, Shiota K, Murata M. Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes. BMC Biol 2009;7:38.
35. Giacchetti G, Faloia E, Taccaliti A, et al. Decreased expression of insulin-sensitive glucose transporter mRNA (GLUT-4) in adipose tissue of non-insulin-dependent diabetic and obese patients: evaluation by a simplified quantitative PCR assay. J Endocrinol Invest 1994;17:709-15.
36. Garvey WT, Maianu L, Hancock JA, Golichowski AM, Baron A. Gene expression of GLUT4 in skeletal muscle from insulin-resistant patients with obesity, IGT, GDM, and NIDDM. Diabetes 1992;41:465-75.
37. Plagemann A, Harder T, Brunn M, et al. Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome. J Physiol 2009;587:4963-76.
38. Brøns C, Jacobsen S, Nilsson E, et al. Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner. J Clin Endocrinol Metab 2010;95:3048-56.
39. Katari S, Turan N, Bibikova M, et al. DNA methylation and gene expression differences in children conceived in vitro or in vivo. Hum Mol Genet 2009;18:3769-78.
40. Ng SF, Lin RC, Laybutt DR, Barres R, Owens JA, Morris MJ. Chronic high-fat diet in fathers programs beta-cell dysfunction in female rat offspring. Nature 2010;467:963-6.