CDK11p46 and RPS8 associate with each other and suppress translation in a synergistic manner

Biochemical and Biophysical Research Communications

Volumn 407, Issue 1, 2011, Pages 169-174

  Hao, Yuqing ^a   Kong, Xiangfei ^a   Ruan, Yuanyuan ^a   Gan, Huachen ^a   Chen, Hong ^a   Zhang, Chunyi ^a   Ren, Shifang ^a   Gu, Jianxin ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

CDK11; Cell apoptosis; RPS8; Translation

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 11 P46; RIBOSOMAL PROTEIN S8; RIBOSOME PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL STRAIN HEK293; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTERNAL RIBOSOME ENTRY SITE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TRANSLATION REGULATION;

AMINO ACID SEQUENCE; APOPTOSIS; CYCLIN-DEPENDENT KINASES; FAS LIGAND PROTEIN; HEK293 CELLS; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BIOSYNTHESIS; RIBOSOMAL PROTEINS;

EID: 79953162233     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.132     Document Type: Article

References (36)

1. Trembley J.H., Loyer P., Hu D., Li T., Grenet J., Lahti J.M., Kidd V.J. Cyclin dependent kinase 11 in RNA transcription and splicing. Prog. Nucleic Acid Res. Mol. Biol. 2004, 77:263-288.
2. Loyer P., Trembley J.H., Katona R., Kidd V.J., Lahti J.M. Role of CDK/cyclin complexes in transcription and RNA splicing. Cell Signal. 2005, 17:1033-1051.
3. Lahti J.M., Xiang J., Heath L.S., Campana D., Kidd V.J. PITSLRE protein kinase activity is associated with apoptosis. Mol. Cell. Biol. 1995, 15:1-11.
4. Trembley J.H., Hu D., Hsu L.C., Yeung C.Y., Slaughter C., Lahti J.M., Kidd V.J. PITSLRE p110 protein kinases associate with transcription complexes and affect their activity. J. Biol. Chem. 2002, 277:2589-2596.
5. Trembley J.H., Hu D., Slaughter C.A., Lahti J.M., Kidd V.J. Casein kinase 2 interacts with cyclin-dependent kinase 11 (CDK11) in vivo and phosphorylates both the RNA polymerase II carboxyl-terminal domain and CDK11 in vitro. J. Biol. Chem. 2003, 278:2265-2270.
6. Loyer P., Trembley J.H., Grenet J.A., Busson A., Corlu A., Zhao W., Kocak M., Kidd V.J., Lahti J.M. Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: influence of cyclin L isoforms on splice site selection. J. Biol. Chem. 2008, 283:7721-7732.
7. Cornelis S., Bruynooghe Y., Denecker G., Van Huffel S., Tinton S., Beyaert R. Identification and characterization of a novel cell cycle-regulated internal ribosome entry site. Mol. Cell 2000, 5:597-605.
8. Bunnell B.A., Heath L.S., Adams D.E., Lahti J.M., Kidd V.J. Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle. Proc. Natl. Acad. Sci. USA 1990, 87:7467-7471.
9. Zhang S., Cai M., Xu S., Chen S., Chen X., Chen C., Gu J. Interaction of p58(PITSLRE), a G2/M-specific protein kinase, with cyclin D3. J. Biol. Chem. 2002, 277:35314-35322.
10. Zong H., Chi Y., Wang Y., Yang Y., Zhang L., Chen H., Jiang J., Li Z., Hong Y., Wang H., Yun X., Gu J. Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor. Mol. Cell. Biol. 2007, 27:7125-7142.
11. Beyaert R., Kidd V.J., Cornelis S., Van de Craen M., Denecker G., Lahti J.M., Gururajan R., Vandenabeele P., Fiers W. Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor. J. Biol. Chem. 1997, 272:11694-11697.
12. Chen S., Yin X., Zhu X., Yan J., Ji S., Chen C., Cai M., Zhang S., Zong H., Hu Y., Yuan Z., Shen Z., Gu J. The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis. J. Biol. Chem. 2003, 278:20029-20036.
13. Shi J., Feng Y., Goulet A.C., Vaillancourt R.R., Sachs N.A., Hershey J.W., Nelson M.A. The p34cdc2-related cyclin-dependent kinase 11 interacts with the p47 subunit of eukaryotic initiation factor 3 during apoptosis. J. Biol. Chem. 2003, 278:5062-5071.
14. Chen C., Yan J., Sun Q., Yao L., Jian Y., Lu J., Gu J. Induction of apoptosis by p110C requires mitochondrial translocation of the proapoptotic BCL-2 family member BAD. FEBS Lett. 2006, 580:813-821.
15. Shi J., Hershey J.W., Nelson M.A. Phosphorylation of the eukaryotic initiation factor 3f by cyclin-dependent kinase 11 during apoptosis. FEBS Lett. 2009, 583:971-977.
16. Jonson L., Vikesaa J., Krogh A., Nielsen L.K., Hansen T., Borup R., Johnsen A.H., Christiansen J., Nielsen F.C. Molecular composition of IMP1 ribonucleoprotein granules. Mol. Cell. Proteomics 2007, 6:798-811.
17. Li Z., Wang H., Zong H., Sun Q., Kong X., Jiang J., Gu J. Downregulation of beta1,4-galactosyltransferase 1 inhibits CDK11(p58)-mediated apoptosis induced by cycloheximide. Biochem. Biophys. Res. Commun. 2005, 327:628-636.
18. Vercoutter-Edouart A.S., Lemoine J., Le Bourhis X., Louis H., Boilly B., Nurcombe V., Revillion F., Peyrat J.P., Hondermarck H. Proteomic analysis reveals that 14-3-3sigma is down-regulated in human breast cancer cells. Cancer Res. 2001, 61:76-80.
19. Cheng C., Kong X., Wang H., Gan H., Hao Y., Zou W., Wu J., Chi Y., Yang J., Hong Y., Chen K., Gu J. Trihydrophobin 1 interacts with PAK1 and regulates ERK/MAPK activation and cell migration. J. Biol. Chem. 2009, 284:8786-8796.
20. Kong X., Gan H., Hao Y., Cheng C., Jiang J., Hong Y., Yang J., Zhu H., Chi Y., Yun X., Gu J. CDK11p58 phosphorylation of PAK1 Ser174 promotes DLC2 binding and roles on cell cycle progression. J. Biochem. 2009, 146:417-427.
21. Wang B., Malik R., Nigg E.A., Korner R. Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis. Anal. Chem. 2008, 80:9526-9533.
22. Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal. Chem. 2009, 81:4493-4501.
23. Gausdal G., Gjertsen B.T., McCormack E., Van Damme P., Hovland R., Krakstad C., Bruserud O., Gevaert K., Vandekerckhove J., Doskeland S.O. Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death. Blood 2008, 111:2866-2877.
24. Robert F., Carrier M., Rawe S., Chen S., Lowe S., Pelletier J. Altering chemosensitivity by modulating translation elongation. PLoS One 2009, 4:e5428.
25. Cencic R., Carrier M., Trnkus A., Porco J.A., Minden M., Pelletier J. Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells. Leuk. Res. 2010, 34:535-541.
26. Shi J., Nelson M.A. The cyclin-dependent kinase 11 interacts with NOT2. Biochem. Biophys. Res. Commun. 2005, 334:1310-1316.
27. Lim J.T., Mansukhani M., Weinstein I.B. Cyclin-dependent kinase 6 associates with the androgen receptor and enhances its transcriptional activity in prostate cancer cells. Proc. Natl. Acad. Sci. USA 2005, 102:5156-5161.
28. Wood L.C., Ashby M.N., Grunfeld C., Feingold K.R. Cloning of murine translation initiation factor 6 and functional analysis of the homologous sequence YPR016c in Saccharomyces cerevisiae. J. Biol. Chem. 1999, 274:11653-11659.
29. Basu U., Si K., Warner J.R., Maitra U. The Saccharomyces cerevisiae TIF6 gene encoding translation initiation factor 6 is required for 60S ribosomal subunit biogenesis. Mol. Cell. Biol. 2001, 21:1453-1462.
30. Ceci M., Gaviraghi C., Gorrini C., Sala L.A., Offenhauser N., Marchisio P.C., Biffo S. Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly. Nature 2003, 426:579-584.
31. Ruggero D., Pandolfi P.P. Does the ribosome translate cancer?. Nat. Rev. Cancer 2003, 3:179-192.
32. Holcik M., Sonenberg N. Translational control in stress and apoptosis. Nat. Rev. Mol. Cell. Biol. 2005, 6:318-327.
33. Barna M., Pusic A., Zollo O., Costa M., Kondrashov N., Rego E., Rao P.H., Ruggero D. Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency. Nature 2008, 456:971-975.
34. Lahti J.M., Valentine M., Xiang J., Jones B., Amann J., Grenet J., Richmond G., Look A.T., Kidd V.J. Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma. Nat. Genet. 1994, 7:370-375.
35. Chandramouli A., Shi J., Feng Y., Holubec H., Shanas R.M., Bhattacharyya A.K., Zheng W., Nelson M.A. Haploinsufficiency of the cdc2l gene contributes to skin cancer development in mice. Carcinogenesis 2007, 28:2028-2035.
36. Ferreira-Cerca S., Hurt E. Cell biology: arrest by ribosome. Nature 2009, 459:46-47.