-
1
-
-
70350780570
-
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways
-
Alarcón, C., Zaromytidou, A. I., Xi, Q., Gao, S., Yu, J., Fujisawa, S., Barlas, A., Miller, A. N., Manova-Todorova, K., Macias, M. J., et al. (2009). Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell 139, 757-769.
-
(2009)
Cell
, vol.139
, pp. 757-769
-
-
Alarcón, C.1
Zaromytidou, A.I.2
Xi, Q.3
Gao, S.4
Yu, J.5
Fujisawa, S.6
Barlas, A.7
Miller, A.N.8
Manova-Todorova, K.9
Macias, M.J.10
-
2
-
-
33751253145
-
Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain
-
Anbanandam, A., Albarado, D. C., Nguyen, C. T., Halder, G., Gao, X., and Veeraraghavan, S. (2006). Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain. Proc Natl Acad Sci U S A 103, 17225-17230.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17225-17230
-
-
Anbanandam, A.1
Albarado, D.C.2
Nguyen, C.T.3
Halder, G.4
Gao, X.5
Veeraraghavan, S.6
-
3
-
-
66149185290
-
Neurofibromatosis type 2
-
Asthagiri, A. R., Parry, D. M., Butman, J. A., Kim, H. J., Tsilou, E. T., Zhuang, Z., and Lonser, R. R. (2009). Neurofibromatosis type 2. Lancet 373, 1974-1986.
-
(2009)
Lancet
, vol.373
, pp. 1974-1986
-
-
Asthagiri, A.R.1
Parry, D.M.2
Butman, J.A.3
Kim, H.J.4
Tsilou, E.T.5
Zhuang, Z.6
Lonser, R.R.7
-
4
-
-
70549083563
-
Herding Hippos: regulating growth in flies and man
-
Badouel, C., Garg, A., and McNeill, H. (2009). Herding Hippos: regulating growth in flies and man. Curr Opin Cell Biol 21, 837-843.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 837-843
-
-
Badouel, C.1
Garg, A.2
McNeill, H.3
-
5
-
-
76249125346
-
The WW domain protein Kibra acts upstream of Hippo in Drosophila
-
Baumgartner, R., Poernbacher, I., Buser, N., Hafen, E., and Stocker, H. (2010). The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev Cell 18, 309-316.
-
(2010)
Dev Cell
, vol.18
, pp. 309-316
-
-
Baumgartner, R.1
Poernbacher, I.2
Buser, N.3
Hafen, E.4
Stocker, H.5
-
6
-
-
57749122174
-
YAP regulates neural progenitor cell number via the TEA domain transcription factor
-
Cao, X., Pfaff, S. L., and Gage, F. H. (2008). YAP regulates neural progenitor cell number via the TEA domain transcription factor. Genes Dev 22, 3320-3334.
-
(2008)
Genes Dev
, vol.22
, pp. 3320-3334
-
-
Cao, X.1
Pfaff, S.L.2
Gage, F.H.3
-
7
-
-
76149134716
-
Structural basis of YAP recognition by TEAD4 in the hippo pathway
-
Chen, L., Chan, S. W., Zhang, X., Walsh, M., Lim, C. J., Hong, W., and Song, H. (2010). Structural basis of YAP recognition by TEAD4 in the hippo pathway. Genes Dev 24, 290-300.
-
(2010)
Genes Dev
, vol.24
, pp. 290-300
-
-
Chen, L.1
Chan, S.W.2
Zhang, X.3
Walsh, M.4
Lim, C.J.5
Hong, W.6
Song, H.7
-
8
-
-
34547688895
-
Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase
-
Couture, J. F., Collazo, E., Ortiz-Tello, P. A., Brunzelle, J. S., and Trievel, R. C. (2007). Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase. Nat Struct Mol Biol 14, 689-695.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 689-695
-
-
Couture, J.F.1
Collazo, E.2
Ortiz-Tello, P.A.3
Brunzelle, J.S.4
Trievel, R.C.5
-
9
-
-
34548636132
-
Elucidation of a universal size-control mechanism in Drosophila and mammals
-
Dong, J., Feldmann, G., Huang, J., Wu, S., Zhang, N., Comerford, S. A., Gayyed, M. F., Anders, R. A., Maitra, A., and Pan, D. (2007). Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 130, 1120-1133.
-
(2007)
Cell
, vol.130
, pp. 1120-1133
-
-
Dong, J.1
Feldmann, G.2
Huang, J.3
Wu, S.4
Zhang, N.5
Comerford, S.A.6
Gayyed, M.F.7
Anders, R.A.8
Maitra, A.9
Pan, D.10
-
10
-
-
31044440368
-
From cell structure to transcription: Hippo forges a new path
-
Edgar, B. A. (2006). From cell structure to transcription: Hippo forges a new path. Cell 124, 267-273.
-
(2006)
Cell
, vol.124
, pp. 267-273
-
-
Edgar, B.A.1
-
11
-
-
76249093838
-
Kibra is a regulator of the Salvador/Warts/Hippo signaling network
-
Genevet, A., Wehr, M. C., Brain, R., Thompson, B. J., and Tapon, N. (2010). Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev Cell 18, 300-308.
-
(2010)
Dev Cell
, vol.18
, pp. 300-308
-
-
Genevet, A.1
Wehr, M.C.2
Brain, R.3
Thompson, B.J.4
Tapon, N.5
-
12
-
-
77955405813
-
Upstream regulation of the hippo size control pathway
-
Grusche, F. A., Richardson, H. E., and Harvey, K. F. (2010). Upstream regulation of the hippo size control pathway. Curr Biol 20, R574-R582.
-
(2010)
Curr Biol
, vol.20
-
-
Grusche, F.A.1
Richardson, H.E.2
Harvey, K.F.3
-
13
-
-
77950485564
-
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms
-
Grzeschik, N. A., Parsons, L. M., Allott, M. L., Harvey, K. F., and Richardson, H. E. (2010). Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr Biol 20, 573-581.
-
(2010)
Curr Biol
, vol.20
, pp. 573-581
-
-
Grzeschik, N.A.1
Parsons, L.M.2
Allott, M.L.3
Harvey, K.F.4
Richardson, H.E.5
-
14
-
-
41949138130
-
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
-
Hao, Y., Chun, A., Cheung, K., Rashidi, B., and Yang, X. (2008). Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J Biol Chem 283, 5496-5509.
-
(2008)
J Biol Chem
, vol.283
, pp. 5496-5509
-
-
Hao, Y.1
Chun, A.2
Cheung, K.3
Rashidi, B.4
Yang, X.5
-
15
-
-
33847206401
-
The Salvador-Warts-Hippo pathway-an emerging tumour-suppressor network
-
Harvey, K., and Tapon, N. (2007). The Salvador-Warts-Hippo pathway-an emerging tumour-suppressor network. Nat Rev Cancer 7, 182-191.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 182-191
-
-
Harvey, K.1
Tapon, N.2
-
16
-
-
0042733354
-
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
-
Harvey, K. F., Pfleger, C. M., and Hariharan, I. K. (2003). The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell 114, 457-467.
-
(2003)
Cell
, vol.114
, pp. 457-467
-
-
Harvey, K.F.1
Pfleger, C.M.2
Hariharan, I.K.3
-
17
-
-
0036800399
-
Molecular alterations of h-warts/LATS1 tumor suppressor in human soft tissue sarcoma
-
Hisaoka, M., Tanaka, A., and Hashimoto, H. (2002). Molecular alterations of h-warts/LATS1 tumor suppressor in human soft tissue sarcoma. Lab Invest 82, 1427-1435.
-
(2002)
Lab Invest
, vol.82
, pp. 1427-1435
-
-
Hisaoka, M.1
Tanaka, A.2
Hashimoto, H.3
-
18
-
-
23744458034
-
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
-
Huang, J., Wu, S., Barrera, J., Matthews, K., and Pan, D. (2005). The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 122, 421-434.
-
(2005)
Cell
, vol.122
, pp. 421-434
-
-
Huang, J.1
Wu, S.2
Barrera, J.3
Matthews, K.4
Pan, D.5
-
19
-
-
28544433969
-
Downregulation of the large tumor suppressor 2 (LATS2/KPM) gene is associated with poor prognosis in acute lymphoblastic leukemia
-
Jiménez-Velasco, A., Román-Gómez, J., Agirre, X., Barrios, M., Navarro, G., Vázquez, I., Prósper, F., Torres, A., and Heiniger, A. (2005). Downregulation of the large tumor suppressor 2 (LATS2/KPM) gene is associated with poor prognosis in acute lymphoblastic leukemia. Leukemia 19, 2347-2350.
-
(2005)
Leukemia
, vol.19
, pp. 2347-2350
-
-
Jiménez-Velasco, A.1
Román-Gómez, J.2
Agirre, X.3
Barrios, M.4
Navarro, G.5
Vázquez, I.6
Prósper, F.7
Torres, A.8
Heiniger, A.9
-
20
-
-
0028902594
-
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
-
Justice, R. W., Zilian, O., Woods, D. F., Noll, M., and Bryant, P. J. (1995). The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev 9, 534-546.
-
(1995)
Genes Dev
, vol.9
, pp. 534-546
-
-
Justice, R.W.1
Zilian, O.2
Woods, D.F.3
Noll, M.4
Bryant, P.J.5
-
21
-
-
0036926950
-
Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila
-
Kango-Singh, M., Nolo, R., Tao, C., Verstreken, P., Hiesinger, P. R., Bellen, H. J., and Halder, G. (2002). Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila. Development 129, 5719-5730.
-
(2002)
Development
, vol.129
, pp. 5719-5730
-
-
Kango-Singh, M.1
Nolo, R.2
Tao, C.3
Verstreken, P.4
Hiesinger, P.R.5
Bellen, H.J.6
Halder, G.7
-
22
-
-
34547907131
-
A Sveinsson's chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ
-
Kitagawa, M. (2007). A Sveinsson's chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ. Biochem Biophys Res Commun 361, 1022-1026.
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 1022-1026
-
-
Kitagawa, M.1
-
23
-
-
35148863626
-
Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer
-
Kosaka, Y., Mimori, K., Tanaka, F., Inoue, H., Watanabe, M., and Mori, M. (2007). Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer. Int J Oncol 31, 333-338.
-
(2007)
Int J Oncol
, vol.31
, pp. 333-338
-
-
Kosaka, Y.1
Mimori, K.2
Tanaka, F.3
Inoue, H.4
Watanabe, M.5
Mori, M.6
-
24
-
-
14844297327
-
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats
-
Lai, Z. C., Wei, X., Shimizu, T., Ramos, E., Rohrbaugh, M., Nikolaidis, N., Ho, L. L., and Li, Y. (2005). Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 120, 675-685.
-
(2005)
Cell
, vol.120
, pp. 675-685
-
-
Lai, Z.C.1
Wei, X.2
Shimizu, T.3
Ramos, E.4
Rohrbaugh, M.5
Nikolaidis, N.6
Ho, L.L.7
Li, Y.8
-
25
-
-
76149138881
-
Structural insights into the YAP and TEAD complex
-
Li, Z., Zhao, B., Wang, P., Chen, F., Dong, Z., Yang, H., Guan, K. L., and Xu, Y. (2010). Structural insights into the YAP and TEAD complex. Genes Dev 24, 235-240.
-
(2010)
Genes Dev
, vol.24
, pp. 235-240
-
-
Li, Z.1
Zhao, B.2
Wang, P.3
Chen, F.4
Dong, Z.5
Yang, H.6
Guan, K.L.7
Xu, Y.8
-
26
-
-
77953738883
-
The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
-
Ling, C., Zheng, Y., Yin, F., Yu, J., Huang, J., Hong, Y., Wu, S., and Pan, D. (2010). The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci U S A 107, 10532-10537.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 10532-10537
-
-
Ling, C.1
Zheng, Y.2
Yin, F.3
Yu, J.4
Huang, J.5
Hong, Y.6
Wu, S.7
Pan, D.8
-
27
-
-
77954770827
-
Targeting YAP and Hippo signaling pathway in liver cancer
-
Liu, A. M., Xu, M. Z., Chen, J., Poon, R. T., and Luk, J. M. (2010). Targeting YAP and Hippo signaling pathway in liver cancer. Expert Opin Ther Targets 14, 855-868.
-
(2010)
Expert Opin Ther Targets
, vol.14
, pp. 855-868
-
-
Liu, A.M.1
Xu, M.Z.2
Chen, J.3
Poon, R.T.4
Luk, J.M.5
-
28
-
-
0029775570
-
Structure of the WW domain of a kinase-associated protein complexed with a prolinerich peptide
-
Macias, M. J., Hyvönen, M., Baraldi, E., Schultz, J., Sudol, M., Saraste, M., and Oschkinat, H. (1996). Structure of the WW domain of a kinase-associated protein complexed with a prolinerich peptide. Nature 382, 646-649.
-
(1996)
Nature
, vol.382
, pp. 646-649
-
-
Macias, M.J.1
Hyvönen, M.2
Baraldi, E.3
Schultz, J.4
Sudol, M.5
Saraste, M.6
Oschkinat, H.7
-
29
-
-
33847379007
-
Prognostic significance of mammalian sterile20-like kinase 1 in colorectal cancer
-
Minoo, P., Zlobec, I., Baker, K., Tornillo, L., Terracciano, L., Jass, J. R., and Lugli, A. (2007). Prognostic significance of mammalian sterile20-like kinase 1 in colorectal cancer. Mod Pathol 20, 331-338.
-
(2007)
Mod Pathol
, vol.20
, pp. 331-338
-
-
Minoo, P.1
Zlobec, I.2
Baker, K.3
Tornillo, L.4
Terracciano, L.5
Jass, J.R.6
Lugli, A.7
-
30
-
-
33749242966
-
The bantam microRNA is a target of the hippo tumor-suppressor pathway
-
Nolo, R., Morrison, C. M., Tao, C., Zhang, X., and Halder, G. (2006). The bantam microRNA is a target of the hippo tumor-suppressor pathway. Curr Biol 16, 1895-1904.
-
(2006)
Curr Biol
, vol.16
, pp. 1895-1904
-
-
Nolo, R.1
Morrison, C.M.2
Tao, C.3
Zhang, X.4
Halder, G.5
-
31
-
-
42549092233
-
In vivo regulation of Yorkie phosphorylation and localization
-
Oh, H., and Irvine, K. D. (2008). In vivo regulation of Yorkie phosphorylation and localization. Development 135, 1081-1088.
-
(2008)
Development
, vol.135
, pp. 1081-1088
-
-
Oh, H.1
Irvine, K.D.2
-
32
-
-
67349136817
-
In vivo analysis of Yorkie phosphorylation sites
-
Oh, H., and Irvine, K. D. (2009). In vivo analysis of Yorkie phosphorylation sites. Oncogene 28, 1916-1927.
-
(2009)
Oncogene
, vol.28
, pp. 1916-1927
-
-
Oh, H.1
Irvine, K.D.2
-
33
-
-
77954313699
-
Yorkie: the final destination of Hippo signaling
-
Oh, H., and Irvine, K. D. (2010). Yorkie: the final destination of Hippo signaling. Trends Cell Biol 20, 410-417.
-
(2010)
Trends Cell Biol
, vol.20
, pp. 410-417
-
-
Oh, H.1
Irvine, K.D.2
-
34
-
-
55549098921
-
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
-
Oka, T., Mazack, V., and Sudol, M. (2008). Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). J Biol Chem 283, 27534-27546.
-
(2008)
J Biol Chem
, vol.283
, pp. 27534-27546
-
-
Oka, T.1
Mazack, V.2
Sudol, M.3
-
35
-
-
60849138138
-
Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling
-
Ota, M., and Sasaki, H. (2008). Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling. Development 135, 4059-4069.
-
(2008)
Development
, vol.135
, pp. 4059-4069
-
-
Ota, M.1
Sasaki, H.2
-
36
-
-
33747591465
-
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
-
Overholtzer, M., Zhang, J., Smolen, G. A., Muir, B., Li, W., Sgroi, D. C., Deng, C. X., Brugge, J. S., and Haber, D. A. (2006). Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon. Proc Natl Acad Sci U S A 103, 12405-12410.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 12405-12410
-
-
Overholtzer, M.1
Zhang, J.2
Smolen, G.A.3
Muir, B.4
Li, W.5
Sgroi, D.C.6
Deng, C.X.7
Brugge, J.S.8
Haber, D.A.9
-
37
-
-
34247191134
-
Hippo signaling in organ size control
-
Pan, D. (2007). Hippo signaling in organ size control. Genes Dev 21, 886-897.
-
(2007)
Genes Dev
, vol.21
, pp. 886-897
-
-
Pan, D.1
-
38
-
-
48749118705
-
The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation
-
Reddy, B. V., and Irvine, K. D. (2008). The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation. Development 135, 2827-2838.
-
(2008)
Development
, vol.135
, pp. 2827-2838
-
-
Reddy, B.V.1
Irvine, K.D.2
-
39
-
-
72649088969
-
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms
-
Ren, F., Zhang, L., and Jiang, J. (2010). Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms. Dev Biol 337, 303-312.
-
(2010)
Dev Biol
, vol.337
, pp. 303-312
-
-
Ren, F.1
Zhang, L.2
Jiang, J.3
-
40
-
-
77950478873
-
Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded
-
Robinson, B. S., Huang, J., Hong, Y., and Moberg, K. H. (2010). Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr Biol 20, 582-590.
-
(2010)
Curr Biol
, vol.20
, pp. 582-590
-
-
Robinson, B.S.1
Huang, J.2
Hong, Y.3
Moberg, K.H.4
-
41
-
-
35148841871
-
Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma
-
Seidel, C., Schagdarsurengin, U., Blümke, K., Würl, P., Pfeifer, G. P., Hauptmann, S., Taubert, H., and Dammann, R. (2007). Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma. Mol Carcinog 46, 865-871.
-
(2007)
Mol Carcinog
, vol.46
, pp. 865-871
-
-
Seidel, C.1
Schagdarsurengin, U.2
Blümke, K.3
Würl, P.4
Pfeifer, G.P.5
Hauptmann, S.6
Taubert, H.7
Dammann, R.8
-
42
-
-
53849087493
-
Expression of Yesassociated protein in common solid tumors
-
Steinhardt, A. A., Gayyed, M. F., Klein, A. P., Dong, J., Maitra, A., Pan, D., Montgomery, E. A., and Anders, R. A. (2008). Expression of Yesassociated protein in common solid tumors. Hum Pathol 39, 1582-1589.
-
(2008)
Hum Pathol
, vol.39
, pp. 1582-1589
-
-
Steinhardt, A.A.1
Gayyed, M.F.2
Klein, A.P.3
Dong, J.4
Maitra, A.5
Pan, D.6
Montgomery, E.A.7
Anders, R.A.8
-
43
-
-
14644420898
-
Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers
-
Takahashi, Y., Miyoshi, Y., Takahata, C., Irahara, N., Taguchi, T., Tamaki, Y., and Noguchi, S. (2005). Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers. Clin Cancer Res 11, 1380-1385.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1380-1385
-
-
Takahashi, Y.1
Miyoshi, Y.2
Takahata, C.3
Irahara, N.4
Taguchi, T.5
Tamaki, Y.6
Noguchi, S.7
-
44
-
-
0032954260
-
Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity
-
Tao, W., Zhang, S., Turenchalk, G. S., Stewart, R. A., St John, M. A., Chen, W., and Xu, T. (1999). Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity. Nat Genet 21, 177-181.
-
(1999)
Nat Genet
, vol.21
, pp. 177-181
-
-
Tao, W.1
Zhang, S.2
Turenchalk, G.S.3
Stewart, R.A.4
St John, M.A.5
Chen, W.6
Xu, T.7
-
45
-
-
0037162714
-
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
-
Tapon, N., Harvey, K. F., Bell, D. W., Wahrer, D. C., Schiripo, T. A., Haber, D. A., and Hariharan, I. K. (2002). salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110, 467-478.
-
(2002)
Cell
, vol.110
, pp. 467-478
-
-
Tapon, N.1
Harvey, K.F.2
Bell, D.W.3
Wahrer, D.C.4
Schiripo, T.A.5
Haber, D.A.6
Hariharan, I.K.7
-
46
-
-
33747159113
-
The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila
-
Thompson, B. J., and Cohen, S. M. (2006). The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell 126, 767-774.
-
(2006)
Cell
, vol.126
, pp. 767-774
-
-
Thompson, B.J.1
Cohen, S.M.2
-
47
-
-
77952116604
-
Structural and functional analysis of the YAP-binding domain of human TEAD2
-
Tian, W., Yu, J., Tomchick, D. R., Pan, D., and Luo, X. (2010). Structural and functional analysis of the YAP-binding domain of human TEAD2. Proc Natl Acad Sci U S A 107, 7293-7298.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 7293-7298
-
-
Tian, W.1
Yu, J.2
Tomchick, D.R.3
Pan, D.4
Luo, X.5
-
48
-
-
46049087598
-
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
-
Varelas, X., Sakuma, R., Samavarchi-Tehrani, P., Peerani, R., Rao, B. M., Dembowy, J., Yaffe, M. B., Zandstra, P. W., and Wrana, J. L. (2008). TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nat Cell Biol 10, 837-848.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 837-848
-
-
Varelas, X.1
Sakuma, R.2
Samavarchi-Tehrani, P.3
Peerani, R.4
Rao, B.M.5
Dembowy, J.6
Yaffe, M.B.7
Zandstra, P.W.8
Wrana, J.L.9
-
49
-
-
0042232429
-
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
-
Wu, S., Huang, J., Dong, J., and Pan, D. (2003). hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell 114, 445-456.
-
(2003)
Cell
, vol.114
, pp. 445-456
-
-
Wu, S.1
Huang, J.2
Dong, J.3
Pan, D.4
-
50
-
-
42049116586
-
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
-
Wu, S., Liu, Y., Zheng, Y., Dong, J., and Pan, D. (2008). The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev Cell 14, 388-398.
-
(2008)
Dev Cell
, vol.14
, pp. 388-398
-
-
Wu, S.1
Liu, Y.2
Zheng, Y.3
Dong, J.4
Pan, D.5
-
51
-
-
0028929414
-
Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase
-
Xu, T., Wang, W., Zhang, S., Stewart, R. A., and Yu, W. (1995). Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development 121, 1053-1063.
-
(1995)
Development
, vol.121
, pp. 1053-1063
-
-
Xu, T.1
Wang, W.2
Zhang, S.3
Stewart, R.A.4
Yu, W.5
-
52
-
-
0037138389
-
How do 14-3-3 proteins work?- Gatekeeper phosphorylation and the molecular anvil hypothesis
-
Yaffe, M. B. (2002). How do 14-3-3 proteins work?- Gatekeeper phosphorylation and the molecular anvil hypothesis. FEBS Lett 513, 53-57.
-
(2002)
FEBS Lett
, vol.513
, pp. 53-57
-
-
Yaffe, M.B.1
-
53
-
-
76249109900
-
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
-
Yu, J., Zheng, Y., Dong, J., Klusza, S., Deng, W. M., and Pan, D. (2010). Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev Cell 18, 288-299.
-
(2010)
Dev Cell
, vol.18
, pp. 288-299
-
-
Yu, J.1
Zheng, Y.2
Dong, J.3
Klusza, S.4
Deng, W.M.5
Pan, D.6
-
54
-
-
33745253109
-
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
-
Zender, L., Spector, M. S., Xue, W., Flemming, P., Cordon-Cardo, C., Silke, J., Fan, S. T., Luk, J. M., Wigler, M., Hannon, G. J., et al. (2006). Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell 125, 1253-1267.
-
(2006)
Cell
, vol.125
, pp. 1253-1267
-
-
Zender, L.1
Spector, M.S.2
Xue, W.3
Flemming, P.4
Cordon-Cardo, C.5
Silke, J.6
Fan, S.T.7
Luk, J.M.8
Wigler, M.9
Hannon, G.J.10
-
55
-
-
39849097306
-
The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals
-
Zeng, Q., and Hong, W. (2008). The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals. Cancer Cell 13, 188-192.
-
(2008)
Cancer Cell
, vol.13
, pp. 188-192
-
-
Zeng, Q.1
Hong, W.2
-
56
-
-
73349128777
-
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
-
Zhang, J., Ji, J. Y., Yu, M., Overholtzer, M., Smolen, G. A., Wang, R., Brugge, J. S., Dyson, N. J., and Haber, D. A. (2009a). YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nat Cell Biol 11, 1444-1450.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1444-1450
-
-
Zhang, J.1
Ji, J.Y.2
Yu, M.3
Overholtzer, M.4
Smolen, G.A.5
Wang, R.6
Brugge, J.S.7
Dyson, N.J.8
Haber, D.A.9
-
57
-
-
69249117040
-
Hippo signaling pathway and organ size control
-
Zhang, L., Yue, T., and Jiang, J. (2009b). Hippo signaling pathway and organ size control. Fly (Austin) 3, 68-73.
-
(2009)
Fly (Austin)
, vol.3
, pp. 68-73
-
-
Zhang, L.1
Yue, T.2
Jiang, J.3
-
58
-
-
35948961118
-
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
-
Zhao, B., Wei, X., Li, W., Udan, R. S., Yang, Q., Kim, J., Xie, J., Ikenoue, T., Yu, J., Li, L., et al. (2007). Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev 21, 2747-2761.
-
(2007)
Genes Dev
, vol.21
, pp. 2747-2761
-
-
Zhao, B.1
Wei, X.2
Li, W.3
Udan, R.S.4
Yang, Q.5
Kim, J.6
Xie, J.7
Ikenoue, T.8
Yu, J.9
Li, L.10
-
59
-
-
57049097531
-
The Hippo-YAP pathway: new connections between regulation of organ size and cancer
-
Zhao, B., Lei, Q. Y., and Guan, K. L. (2008a). The Hippo-YAP pathway: new connections between regulation of organ size and cancer. Curr Opin Cell Biol 20, 638-646.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 638-646
-
-
Zhao, B.1
Lei, Q.Y.2
Guan, K.L.3
-
60
-
-
47549095853
-
TEAD mediates YAP-dependent gene induction and growth control
-
Zhao, B., Ye, X., Yu, J., Li, L., Li, W., Li, S., Yu, J., Lin, J. D., Wang, C. Y., Chinnaiyan, A. M., et al. (2008b). TEAD mediates YAP-dependent gene induction and growth control. Genes Dev 22, 1962-1971.
-
(2008)
Genes Dev
, vol.22
, pp. 1962-1971
-
-
Zhao, B.1
Ye, X.2
Yu, J.3
Li, L.4
Li, W.5
Li, S.6
Yu, J.7
Lin, J.D.8
Wang, C.Y.9
Chinnaiyan, A.M.10
-
61
-
-
59149088576
-
Both TEADbinding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein
-
Zhao, B., Kim, J., Ye, X., Lai, Z. C., and Guan, K. L. (2009). Both TEADbinding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein. Cancer Res 69, 1089-1098.
-
(2009)
Cancer Res
, vol.69
, pp. 1089-1098
-
-
Zhao, B.1
Kim, J.2
Ye, X.3
Lai, Z.C.4
Guan, K.L.5
-
62
-
-
77951837150
-
The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
-
Zhao, B., Li, L., Lei, Q., and Guan, K. L. (2010a). The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev 24, 862-874.
-
(2010)
Genes Dev
, vol.24
, pp. 862-874
-
-
Zhao, B.1
Li, L.2
Lei, Q.3
Guan, K.L.4
-
63
-
-
73549095761
-
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
-
Zhao, B., Li, L., Tumaneng, K., Wang, C. Y., and Guan, K. L. (2010b). A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev 24, 72-85.
-
(2010)
Genes Dev
, vol.24
, pp. 72-85
-
-
Zhao, B.1
Li, L.2
Tumaneng, K.3
Wang, C.Y.4
Guan, K.L.5
|