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Volumn 1, Issue 9, 2010, Pages 811-819

Snapshots of a hybrid transcription factor in the Hippo pathway

Author keywords

cancer; Hippo; phosphorylation; structure; TEAD; YAP

Indexed keywords

PROTEIN 14 3 3; PROTEIN KINASE; PROTEIN KINASE HIPPO; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TEAD; TRANSCRIPTION FACTOR YAP; UNCLASSIFIED DRUG;

EID: 79953139750     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-010-0105-z     Document Type: Review
Times cited : (13)

References (63)
  • 2
    • 33751253145 scopus 로고    scopus 로고
    • Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain
    • Anbanandam, A., Albarado, D. C., Nguyen, C. T., Halder, G., Gao, X., and Veeraraghavan, S. (2006). Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain. Proc Natl Acad Sci U S A 103, 17225-17230.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17225-17230
    • Anbanandam, A.1    Albarado, D.C.2    Nguyen, C.T.3    Halder, G.4    Gao, X.5    Veeraraghavan, S.6
  • 4
    • 70549083563 scopus 로고    scopus 로고
    • Herding Hippos: regulating growth in flies and man
    • Badouel, C., Garg, A., and McNeill, H. (2009). Herding Hippos: regulating growth in flies and man. Curr Opin Cell Biol 21, 837-843.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 837-843
    • Badouel, C.1    Garg, A.2    McNeill, H.3
  • 5
    • 76249125346 scopus 로고    scopus 로고
    • The WW domain protein Kibra acts upstream of Hippo in Drosophila
    • Baumgartner, R., Poernbacher, I., Buser, N., Hafen, E., and Stocker, H. (2010). The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev Cell 18, 309-316.
    • (2010) Dev Cell , vol.18 , pp. 309-316
    • Baumgartner, R.1    Poernbacher, I.2    Buser, N.3    Hafen, E.4    Stocker, H.5
  • 6
    • 57749122174 scopus 로고    scopus 로고
    • YAP regulates neural progenitor cell number via the TEA domain transcription factor
    • Cao, X., Pfaff, S. L., and Gage, F. H. (2008). YAP regulates neural progenitor cell number via the TEA domain transcription factor. Genes Dev 22, 3320-3334.
    • (2008) Genes Dev , vol.22 , pp. 3320-3334
    • Cao, X.1    Pfaff, S.L.2    Gage, F.H.3
  • 7
    • 76149134716 scopus 로고    scopus 로고
    • Structural basis of YAP recognition by TEAD4 in the hippo pathway
    • Chen, L., Chan, S. W., Zhang, X., Walsh, M., Lim, C. J., Hong, W., and Song, H. (2010). Structural basis of YAP recognition by TEAD4 in the hippo pathway. Genes Dev 24, 290-300.
    • (2010) Genes Dev , vol.24 , pp. 290-300
    • Chen, L.1    Chan, S.W.2    Zhang, X.3    Walsh, M.4    Lim, C.J.5    Hong, W.6    Song, H.7
  • 10
    • 31044440368 scopus 로고    scopus 로고
    • From cell structure to transcription: Hippo forges a new path
    • Edgar, B. A. (2006). From cell structure to transcription: Hippo forges a new path. Cell 124, 267-273.
    • (2006) Cell , vol.124 , pp. 267-273
    • Edgar, B.A.1
  • 11
    • 76249093838 scopus 로고    scopus 로고
    • Kibra is a regulator of the Salvador/Warts/Hippo signaling network
    • Genevet, A., Wehr, M. C., Brain, R., Thompson, B. J., and Tapon, N. (2010). Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev Cell 18, 300-308.
    • (2010) Dev Cell , vol.18 , pp. 300-308
    • Genevet, A.1    Wehr, M.C.2    Brain, R.3    Thompson, B.J.4    Tapon, N.5
  • 12
    • 77955405813 scopus 로고    scopus 로고
    • Upstream regulation of the hippo size control pathway
    • Grusche, F. A., Richardson, H. E., and Harvey, K. F. (2010). Upstream regulation of the hippo size control pathway. Curr Biol 20, R574-R582.
    • (2010) Curr Biol , vol.20
    • Grusche, F.A.1    Richardson, H.E.2    Harvey, K.F.3
  • 13
    • 77950485564 scopus 로고    scopus 로고
    • Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms
    • Grzeschik, N. A., Parsons, L. M., Allott, M. L., Harvey, K. F., and Richardson, H. E. (2010). Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr Biol 20, 573-581.
    • (2010) Curr Biol , vol.20 , pp. 573-581
    • Grzeschik, N.A.1    Parsons, L.M.2    Allott, M.L.3    Harvey, K.F.4    Richardson, H.E.5
  • 14
    • 41949138130 scopus 로고    scopus 로고
    • Tumor suppressor LATS1 is a negative regulator of oncogene YAP
    • Hao, Y., Chun, A., Cheung, K., Rashidi, B., and Yang, X. (2008). Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J Biol Chem 283, 5496-5509.
    • (2008) J Biol Chem , vol.283 , pp. 5496-5509
    • Hao, Y.1    Chun, A.2    Cheung, K.3    Rashidi, B.4    Yang, X.5
  • 15
    • 33847206401 scopus 로고    scopus 로고
    • The Salvador-Warts-Hippo pathway-an emerging tumour-suppressor network
    • Harvey, K., and Tapon, N. (2007). The Salvador-Warts-Hippo pathway-an emerging tumour-suppressor network. Nat Rev Cancer 7, 182-191.
    • (2007) Nat Rev Cancer , vol.7 , pp. 182-191
    • Harvey, K.1    Tapon, N.2
  • 16
    • 0042733354 scopus 로고    scopus 로고
    • The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
    • Harvey, K. F., Pfleger, C. M., and Hariharan, I. K. (2003). The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell 114, 457-467.
    • (2003) Cell , vol.114 , pp. 457-467
    • Harvey, K.F.1    Pfleger, C.M.2    Hariharan, I.K.3
  • 17
    • 0036800399 scopus 로고    scopus 로고
    • Molecular alterations of h-warts/LATS1 tumor suppressor in human soft tissue sarcoma
    • Hisaoka, M., Tanaka, A., and Hashimoto, H. (2002). Molecular alterations of h-warts/LATS1 tumor suppressor in human soft tissue sarcoma. Lab Invest 82, 1427-1435.
    • (2002) Lab Invest , vol.82 , pp. 1427-1435
    • Hisaoka, M.1    Tanaka, A.2    Hashimoto, H.3
  • 18
    • 23744458034 scopus 로고    scopus 로고
    • The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
    • Huang, J., Wu, S., Barrera, J., Matthews, K., and Pan, D. (2005). The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 122, 421-434.
    • (2005) Cell , vol.122 , pp. 421-434
    • Huang, J.1    Wu, S.2    Barrera, J.3    Matthews, K.4    Pan, D.5
  • 20
    • 0028902594 scopus 로고
    • The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
    • Justice, R. W., Zilian, O., Woods, D. F., Noll, M., and Bryant, P. J. (1995). The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev 9, 534-546.
    • (1995) Genes Dev , vol.9 , pp. 534-546
    • Justice, R.W.1    Zilian, O.2    Woods, D.F.3    Noll, M.4    Bryant, P.J.5
  • 22
    • 34547907131 scopus 로고    scopus 로고
    • A Sveinsson's chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ
    • Kitagawa, M. (2007). A Sveinsson's chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ. Biochem Biophys Res Commun 361, 1022-1026.
    • (2007) Biochem Biophys Res Commun , vol.361 , pp. 1022-1026
    • Kitagawa, M.1
  • 23
    • 35148863626 scopus 로고    scopus 로고
    • Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer
    • Kosaka, Y., Mimori, K., Tanaka, F., Inoue, H., Watanabe, M., and Mori, M. (2007). Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer. Int J Oncol 31, 333-338.
    • (2007) Int J Oncol , vol.31 , pp. 333-338
    • Kosaka, Y.1    Mimori, K.2    Tanaka, F.3    Inoue, H.4    Watanabe, M.5    Mori, M.6
  • 24
    • 14844297327 scopus 로고    scopus 로고
    • Control of cell proliferation and apoptosis by mob as tumor suppressor, mats
    • Lai, Z. C., Wei, X., Shimizu, T., Ramos, E., Rohrbaugh, M., Nikolaidis, N., Ho, L. L., and Li, Y. (2005). Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 120, 675-685.
    • (2005) Cell , vol.120 , pp. 675-685
    • Lai, Z.C.1    Wei, X.2    Shimizu, T.3    Ramos, E.4    Rohrbaugh, M.5    Nikolaidis, N.6    Ho, L.L.7    Li, Y.8
  • 26
    • 77953738883 scopus 로고    scopus 로고
    • The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
    • Ling, C., Zheng, Y., Yin, F., Yu, J., Huang, J., Hong, Y., Wu, S., and Pan, D. (2010). The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci U S A 107, 10532-10537.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 10532-10537
    • Ling, C.1    Zheng, Y.2    Yin, F.3    Yu, J.4    Huang, J.5    Hong, Y.6    Wu, S.7    Pan, D.8
  • 27
  • 28
    • 0029775570 scopus 로고    scopus 로고
    • Structure of the WW domain of a kinase-associated protein complexed with a prolinerich peptide
    • Macias, M. J., Hyvönen, M., Baraldi, E., Schultz, J., Sudol, M., Saraste, M., and Oschkinat, H. (1996). Structure of the WW domain of a kinase-associated protein complexed with a prolinerich peptide. Nature 382, 646-649.
    • (1996) Nature , vol.382 , pp. 646-649
    • Macias, M.J.1    Hyvönen, M.2    Baraldi, E.3    Schultz, J.4    Sudol, M.5    Saraste, M.6    Oschkinat, H.7
  • 29
    • 33847379007 scopus 로고    scopus 로고
    • Prognostic significance of mammalian sterile20-like kinase 1 in colorectal cancer
    • Minoo, P., Zlobec, I., Baker, K., Tornillo, L., Terracciano, L., Jass, J. R., and Lugli, A. (2007). Prognostic significance of mammalian sterile20-like kinase 1 in colorectal cancer. Mod Pathol 20, 331-338.
    • (2007) Mod Pathol , vol.20 , pp. 331-338
    • Minoo, P.1    Zlobec, I.2    Baker, K.3    Tornillo, L.4    Terracciano, L.5    Jass, J.R.6    Lugli, A.7
  • 30
    • 33749242966 scopus 로고    scopus 로고
    • The bantam microRNA is a target of the hippo tumor-suppressor pathway
    • Nolo, R., Morrison, C. M., Tao, C., Zhang, X., and Halder, G. (2006). The bantam microRNA is a target of the hippo tumor-suppressor pathway. Curr Biol 16, 1895-1904.
    • (2006) Curr Biol , vol.16 , pp. 1895-1904
    • Nolo, R.1    Morrison, C.M.2    Tao, C.3    Zhang, X.4    Halder, G.5
  • 31
    • 42549092233 scopus 로고    scopus 로고
    • In vivo regulation of Yorkie phosphorylation and localization
    • Oh, H., and Irvine, K. D. (2008). In vivo regulation of Yorkie phosphorylation and localization. Development 135, 1081-1088.
    • (2008) Development , vol.135 , pp. 1081-1088
    • Oh, H.1    Irvine, K.D.2
  • 32
    • 67349136817 scopus 로고    scopus 로고
    • In vivo analysis of Yorkie phosphorylation sites
    • Oh, H., and Irvine, K. D. (2009). In vivo analysis of Yorkie phosphorylation sites. Oncogene 28, 1916-1927.
    • (2009) Oncogene , vol.28 , pp. 1916-1927
    • Oh, H.1    Irvine, K.D.2
  • 33
    • 77954313699 scopus 로고    scopus 로고
    • Yorkie: the final destination of Hippo signaling
    • Oh, H., and Irvine, K. D. (2010). Yorkie: the final destination of Hippo signaling. Trends Cell Biol 20, 410-417.
    • (2010) Trends Cell Biol , vol.20 , pp. 410-417
    • Oh, H.1    Irvine, K.D.2
  • 34
    • 55549098921 scopus 로고    scopus 로고
    • Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)
    • Oka, T., Mazack, V., and Sudol, M. (2008). Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). J Biol Chem 283, 27534-27546.
    • (2008) J Biol Chem , vol.283 , pp. 27534-27546
    • Oka, T.1    Mazack, V.2    Sudol, M.3
  • 35
    • 60849138138 scopus 로고    scopus 로고
    • Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling
    • Ota, M., and Sasaki, H. (2008). Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling. Development 135, 4059-4069.
    • (2008) Development , vol.135 , pp. 4059-4069
    • Ota, M.1    Sasaki, H.2
  • 37
    • 34247191134 scopus 로고    scopus 로고
    • Hippo signaling in organ size control
    • Pan, D. (2007). Hippo signaling in organ size control. Genes Dev 21, 886-897.
    • (2007) Genes Dev , vol.21 , pp. 886-897
    • Pan, D.1
  • 38
    • 48749118705 scopus 로고    scopus 로고
    • The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation
    • Reddy, B. V., and Irvine, K. D. (2008). The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation. Development 135, 2827-2838.
    • (2008) Development , vol.135 , pp. 2827-2838
    • Reddy, B.V.1    Irvine, K.D.2
  • 39
    • 72649088969 scopus 로고    scopus 로고
    • Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms
    • Ren, F., Zhang, L., and Jiang, J. (2010). Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms. Dev Biol 337, 303-312.
    • (2010) Dev Biol , vol.337 , pp. 303-312
    • Ren, F.1    Zhang, L.2    Jiang, J.3
  • 40
    • 77950478873 scopus 로고    scopus 로고
    • Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded
    • Robinson, B. S., Huang, J., Hong, Y., and Moberg, K. H. (2010). Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr Biol 20, 582-590.
    • (2010) Curr Biol , vol.20 , pp. 582-590
    • Robinson, B.S.1    Huang, J.2    Hong, Y.3    Moberg, K.H.4
  • 43
    • 14644420898 scopus 로고    scopus 로고
    • Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers
    • Takahashi, Y., Miyoshi, Y., Takahata, C., Irahara, N., Taguchi, T., Tamaki, Y., and Noguchi, S. (2005). Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers. Clin Cancer Res 11, 1380-1385.
    • (2005) Clin Cancer Res , vol.11 , pp. 1380-1385
    • Takahashi, Y.1    Miyoshi, Y.2    Takahata, C.3    Irahara, N.4    Taguchi, T.5    Tamaki, Y.6    Noguchi, S.7
  • 44
    • 0032954260 scopus 로고    scopus 로고
    • Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity
    • Tao, W., Zhang, S., Turenchalk, G. S., Stewart, R. A., St John, M. A., Chen, W., and Xu, T. (1999). Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity. Nat Genet 21, 177-181.
    • (1999) Nat Genet , vol.21 , pp. 177-181
    • Tao, W.1    Zhang, S.2    Turenchalk, G.S.3    Stewart, R.A.4    St John, M.A.5    Chen, W.6    Xu, T.7
  • 45
    • 0037162714 scopus 로고    scopus 로고
    • salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
    • Tapon, N., Harvey, K. F., Bell, D. W., Wahrer, D. C., Schiripo, T. A., Haber, D. A., and Hariharan, I. K. (2002). salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110, 467-478.
    • (2002) Cell , vol.110 , pp. 467-478
    • Tapon, N.1    Harvey, K.F.2    Bell, D.W.3    Wahrer, D.C.4    Schiripo, T.A.5    Haber, D.A.6    Hariharan, I.K.7
  • 46
    • 33747159113 scopus 로고    scopus 로고
    • The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila
    • Thompson, B. J., and Cohen, S. M. (2006). The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell 126, 767-774.
    • (2006) Cell , vol.126 , pp. 767-774
    • Thompson, B.J.1    Cohen, S.M.2
  • 47
    • 77952116604 scopus 로고    scopus 로고
    • Structural and functional analysis of the YAP-binding domain of human TEAD2
    • Tian, W., Yu, J., Tomchick, D. R., Pan, D., and Luo, X. (2010). Structural and functional analysis of the YAP-binding domain of human TEAD2. Proc Natl Acad Sci U S A 107, 7293-7298.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 7293-7298
    • Tian, W.1    Yu, J.2    Tomchick, D.R.3    Pan, D.4    Luo, X.5
  • 49
    • 0042232429 scopus 로고    scopus 로고
    • hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
    • Wu, S., Huang, J., Dong, J., and Pan, D. (2003). hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell 114, 445-456.
    • (2003) Cell , vol.114 , pp. 445-456
    • Wu, S.1    Huang, J.2    Dong, J.3    Pan, D.4
  • 50
    • 42049116586 scopus 로고    scopus 로고
    • The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
    • Wu, S., Liu, Y., Zheng, Y., Dong, J., and Pan, D. (2008). The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev Cell 14, 388-398.
    • (2008) Dev Cell , vol.14 , pp. 388-398
    • Wu, S.1    Liu, Y.2    Zheng, Y.3    Dong, J.4    Pan, D.5
  • 51
    • 0028929414 scopus 로고
    • Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase
    • Xu, T., Wang, W., Zhang, S., Stewart, R. A., and Yu, W. (1995). Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development 121, 1053-1063.
    • (1995) Development , vol.121 , pp. 1053-1063
    • Xu, T.1    Wang, W.2    Zhang, S.3    Stewart, R.A.4    Yu, W.5
  • 52
    • 0037138389 scopus 로고    scopus 로고
    • How do 14-3-3 proteins work?- Gatekeeper phosphorylation and the molecular anvil hypothesis
    • Yaffe, M. B. (2002). How do 14-3-3 proteins work?- Gatekeeper phosphorylation and the molecular anvil hypothesis. FEBS Lett 513, 53-57.
    • (2002) FEBS Lett , vol.513 , pp. 53-57
    • Yaffe, M.B.1
  • 53
    • 76249109900 scopus 로고    scopus 로고
    • Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
    • Yu, J., Zheng, Y., Dong, J., Klusza, S., Deng, W. M., and Pan, D. (2010). Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev Cell 18, 288-299.
    • (2010) Dev Cell , vol.18 , pp. 288-299
    • Yu, J.1    Zheng, Y.2    Dong, J.3    Klusza, S.4    Deng, W.M.5    Pan, D.6
  • 55
    • 39849097306 scopus 로고    scopus 로고
    • The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals
    • Zeng, Q., and Hong, W. (2008). The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals. Cancer Cell 13, 188-192.
    • (2008) Cancer Cell , vol.13 , pp. 188-192
    • Zeng, Q.1    Hong, W.2
  • 56
    • 73349128777 scopus 로고    scopus 로고
    • YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
    • Zhang, J., Ji, J. Y., Yu, M., Overholtzer, M., Smolen, G. A., Wang, R., Brugge, J. S., Dyson, N. J., and Haber, D. A. (2009a). YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nat Cell Biol 11, 1444-1450.
    • (2009) Nat Cell Biol , vol.11 , pp. 1444-1450
    • Zhang, J.1    Ji, J.Y.2    Yu, M.3    Overholtzer, M.4    Smolen, G.A.5    Wang, R.6    Brugge, J.S.7    Dyson, N.J.8    Haber, D.A.9
  • 57
    • 69249117040 scopus 로고    scopus 로고
    • Hippo signaling pathway and organ size control
    • Zhang, L., Yue, T., and Jiang, J. (2009b). Hippo signaling pathway and organ size control. Fly (Austin) 3, 68-73.
    • (2009) Fly (Austin) , vol.3 , pp. 68-73
    • Zhang, L.1    Yue, T.2    Jiang, J.3
  • 58
    • 35948961118 scopus 로고    scopus 로고
    • Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
    • Zhao, B., Wei, X., Li, W., Udan, R. S., Yang, Q., Kim, J., Xie, J., Ikenoue, T., Yu, J., Li, L., et al. (2007). Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev 21, 2747-2761.
    • (2007) Genes Dev , vol.21 , pp. 2747-2761
    • Zhao, B.1    Wei, X.2    Li, W.3    Udan, R.S.4    Yang, Q.5    Kim, J.6    Xie, J.7    Ikenoue, T.8    Yu, J.9    Li, L.10
  • 59
    • 57049097531 scopus 로고    scopus 로고
    • The Hippo-YAP pathway: new connections between regulation of organ size and cancer
    • Zhao, B., Lei, Q. Y., and Guan, K. L. (2008a). The Hippo-YAP pathway: new connections between regulation of organ size and cancer. Curr Opin Cell Biol 20, 638-646.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 638-646
    • Zhao, B.1    Lei, Q.Y.2    Guan, K.L.3
  • 61
    • 59149088576 scopus 로고    scopus 로고
    • Both TEADbinding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein
    • Zhao, B., Kim, J., Ye, X., Lai, Z. C., and Guan, K. L. (2009). Both TEADbinding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein. Cancer Res 69, 1089-1098.
    • (2009) Cancer Res , vol.69 , pp. 1089-1098
    • Zhao, B.1    Kim, J.2    Ye, X.3    Lai, Z.C.4    Guan, K.L.5
  • 62
    • 77951837150 scopus 로고    scopus 로고
    • The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
    • Zhao, B., Li, L., Lei, Q., and Guan, K. L. (2010a). The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev 24, 862-874.
    • (2010) Genes Dev , vol.24 , pp. 862-874
    • Zhao, B.1    Li, L.2    Lei, Q.3    Guan, K.L.4
  • 63
    • 73549095761 scopus 로고    scopus 로고
    • A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
    • Zhao, B., Li, L., Tumaneng, K., Wang, C. Y., and Guan, K. L. (2010b). A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev 24, 72-85.
    • (2010) Genes Dev , vol.24 , pp. 72-85
    • Zhao, B.1    Li, L.2    Tumaneng, K.3    Wang, C.Y.4    Guan, K.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.