Modeling of shear stress experienced by endothelial cells cultured on microstructured polymer substrates in a parallel plate flow chamber

Biotechnology and Bioengineering

Volumn 108, Issue 5, 2011, Pages 1148-1158

  Brown, Alan ^a   Burke, George ^a   Meenan, Brian J ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

Bioreactor; Computational fluid dynamics; Microstructure; Shear stress; Tissue engineering; Topography

Indexed keywords

CELL MONOLAYERS; CELL POPULATIONS; CELL RESPONSE; CFD MODELS; COMBINED EFFECT; CONFOCAL LASER SCANNING MICROSCOPY; IN-CELL; LAMINAR SHEAR STRESS; MECHANICAL STIMULUS; MICROSTRUCTURED SURFACES; ONE-FORM; PARALLEL PLATE FLOW CHAMBER; POLYMER SUBSTRATE; PRE-ALIGNED; REGENERATIVE MEDICINE; SHEAR STRESS DISTRIBUTION; SPATIAL GRADIENTS; SURFACE FEATURE; TISSUE CULTURE POLYSTYRENES; TOPOGRAPHIC INFORMATION;

BACTERIOLOGY; BIOREACTORS; CELL PROLIFERATION; COMPUTATIONAL FLUID DYNAMICS; CONFOCAL MICROSCOPY; ELECTRON ENERGY LEVELS; ENDOTHELIAL CELLS; FLUID DYNAMICS; FLUIDS; MICROSTRUCTURE; MONOLAYERS; PARALLEL FLOW; PLATES (STRUCTURAL COMPONENTS); POLYSTYRENES; SELF ASSEMBLY; SHEAR FLOW; SHEAR STRESS; STRENGTH OF MATERIALS; STRESS CONCENTRATION; SUBSTRATES; TISSUE; TISSUE CULTURE; TISSUE ENGINEERING; TOPOGRAPHY;

CELL CULTURE;

MICROSTRUCTURED TISSUE CULTURE POLYSTYRENE; POLYSTYRENE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE EQUIPMENT; CELL SHAPE; CELL STIMULATION; COMPUTATIONAL FLUID DYNAMICS; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENDOTHELIUM CELL; LAMINAR FLOW; MATHEMATICAL MODEL; MONOLAYER CULTURE; NONHUMAN; PARALLEL PLATE FLOW CHAMBER; SHEAR STRESS; TOPOGRAPHY;

ANIMALS; CATTLE; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; MODELS, BIOLOGICAL; POLYMERS;

EID: 79953139466     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23022     Document Type: Article

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