Tangential beam IMRT versus tangential beam 3D-CRT of the chest wall in postmastectomy breast cancer patients: A dosimetric comparison

Radiation Oncology

Volumn 6, Issue 1, 2011, Pages

  Rudat, Volker ^a   Aziz Alaradi, Abdul ^a   Mohamed, Adel ^a   AI Yahya, Khaled ^a   Altuwaijri, Saleh ^a  

^a SAAD SPECIALIST HOSPITAL   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BREAST CANCER; CLINICAL ARTICLE; COMPUTER ASSISTED RADIOTHERAPY; DOSIMETRY; FEMALE; HEART; HISTOGRAM; HUMAN; INTENSITY MODULATED RADIATION THERAPY; INTERMETHOD COMPARISON; LUNG; MASTECTOMY; RADIATION DOSE DISTRIBUTION; STATISTICS; THORAX WALL; ADJUVANT THERAPY; BREAST TUMOR; COMPARATIVE STUDY; EVALUATION; INSTRUMENTATION; METHODOLOGY; ORGANS AT RISK; RADIATION DOSE; RADIATION EXPOSURE; RADIOMETRY; RETROSPECTIVE STUDY; SEGMENTAL MASTECTOMY; THREE DIMENSIONAL IMAGING;

BREAST NEOPLASMS; FEMALE; HUMANS; IMAGING, THREE-DIMENSIONAL; MASTECTOMY, SEGMENTAL; ORGANS AT RISK; RADIATION DOSAGE; RADIOMETRY; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, ADJUVANT; RADIOTHERAPY, CONFORMAL; RADIOTHERAPY, INTENSITY-MODULATED; RETROSPECTIVE STUDIES; THORACIC WALL;

EID: 79953106435     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-6-26     Document Type: Article

References (68)

1. Habermann EB, Abbott A, Parsons HM, Virnig BA, Al-Refaie WB, Tuttle TM. Are mastectomy rates really increasing in the United States?. J Clin Oncol 2010, 28(21):3437-3441. 10.1200/JCO.2009.27.6774, 20548000.
2. El Saghir NS, Khalil MK, Eid T, El Kinge AR, Charafeddine M, Geara F, Seoud M, Shamseddine AI. Trends in epidemiology and management of breast cancer in developing Arab countries: a literature and registry analysis. Int J Surg 2007, 5(4):225-233. 10.1016/j.ijsu.2006.06.015, 17660128.
3. Overgaard M, Nielsen HM, Overgaard J. Is the benefit of postmastectomy irradiation limited to patients with four or more positive nodes, as recommended in international consensus reports? A subgroup analysis of the DBCG 82 b&c randomized trials. Radiother Oncol 2007, 82(3):247-253. 10.1016/j.radonc.2007.02.001, 17306393.
4. Clarke M, Collins R, Darby S, Davies C, Elphinstone P, Evans E, Godwin J, Gray R, Hicks C, James S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005, 366(9503):2087-2106.
5. Zablotska LB, Neugut AI. Lung carcinoma after radiation therapy in women treated with lumpectomy or mastectomy for primary breast carcinoma. Cancer 2003, 97(6):1404-1411. 10.1002/cncr.11214, 12627503.
6. Travis LB, Curtis RE, Inskip PD, Hankey BF. Re: Lung cancer risk and radiation dose among women treated for breast cancer. J Natl Cancer Inst 1995, 87(1):60-61. 10.1093/jnci/87.1.60, 7666469.
7. Rubino C, de Vathaire F, Shamsaldin A, Labbe M, Le MG. Radiation dose, chemotherapy, hormonal treatment and risk of second cancer after breast cancer treatment. Br J Cancer 2003, 89(5):840-846. 10.1038/sj.bjc.6601138, 2394476, 12942115.
8. Berrington de Gonzalez A, Curtis RE, Gilbert E, Berg CD, Smith SA, Stovall M, Ron E. Second solid cancers after radiotherapy for breast cancer in SEER cancer registries. Br J Cancer 2010, 102(1):220-226. 10.1038/sj.bjc.6605435, 2813734, 19935795.
9. Fisher B, Jeong JH, Anderson S, Bryant J, Fisher ER, Wolmark N. Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation. N Engl J Med 2002, 347(8):567-575. 10.1056/NEJMoa020128, 12192016.
10. Roychoudhuri R, Robinson D, Putcha V, Cuzick J, Darby S, Moller H. Increased cardiovascular mortality more than fifteen years after radiotherapy for breast cancer: a population-based study. BMC Cancer 2007, 7:9. 10.1186/1471-2407-7-9, 1784099, 17224064.
11. Prochazka M, Granath F, Ekbom A, Shields PG, Hall P. Lung cancer risks in women with previous breast cancer. Eur J Cancer 2002, 38(11):1520-1525. 10.1016/S0959-8049(02)00089-8, 12110499.
12. Galper S, Gelman R, Recht A, Silver B, Kohli A, Wong JS, Van Buren T, Baldini EH, Harris JR. Second nonbreast malignancies after conservative surgery and radiation therapy for early-stage breast cancer. Int J Radiat Oncol Biol Phys 2002, 52(2):406-414. 10.1016/S0360-3016(01)02661-X, 11872286.
13. Giordano SH, Kuo YF, Freeman JL, Buchholz TA, Hortobagyi GN, Goodwin JS. Risk of cardiac death after adjuvant radiotherapy for breast cancer. J Natl Cancer Inst 2005, 97(6):419-424. 10.1093/jnci/dji067, 1853253, 15770005.
14. Darby SC, McGale P, Taylor CW, Peto R. Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300,000 women in US SEER cancer registries. Lancet Oncol 2005, 6(8):557-565. 10.1016/S1470-2045(05)70251-5, 16054566.
15. Darby S, McGale P, Peto R, Granath F, Hall P, Ekbom A. Mortality from cardiovascular disease more than 10 years after radiotherapy for breast cancer: nationwide cohort study of 90 000 Swedish women. BMJ 2003, 326(7383):256-257. 10.1136/bmj.326.7383.256, 140764, 12560277.
16. Cuzick J, Stewart H, Rutqvist L, Houghton J, Edwards R, Redmond C, Peto R, Baum M, Fisher B, Host H, et al. Cause-specific mortality in long-term survivors of breast cancer who participated in trials of radiotherapy. J Clin Oncol 1994, 12(3):447-453.
17. Rutqvist LE, Lax I, Fornander T, Johansson H. Cardiovascular mortality in a randomized trial of adjuvant radiation therapy versus surgery alone in primary breast cancer. Int J Radiat Oncol Biol Phys 1992, 22(5):887-896. 10.1016/0360-3016(92)90784-F, 1555981.
18. Host H, Brennhovd IO, Loeb M. Postoperative radiotherapy in breast cancer--long-term results from the Oslo study. Int J Radiat Oncol Biol Phys 1986, 12(5):727-732. 10.1016/0360-3016(86)90029-5, 3519550.
19. Haybittle JL, Brinkley D, Houghton J, A'Hern RP, Baum M. Postoperative radiotherapy and late mortality: evidence from the Cancer Research Campaign trial for early breast cancer. BMJ 1989, 298(6688):1611-1614. 10.1136/bmj.298.6688.1611, 1836871, 2503148.
20. Jones JM, Ribeiro GG. Mortality patterns over 34 years of breast cancer patients in a clinical trial of post-operative radiotherapy. Clin Radiol 1989, 40(2):204-208. 10.1016/S0009-9260(89)80099-6, 2647360.
21. Paszat LF, Mackillop WJ, Groome PA, Schulze K, Holowaty E. Mortality from myocardial infarction following postlumpectomy radiotherapy for breast cancer: a population-based study in Ontario, Canada. Int J Radiat Oncol Biol Phys 1999, 43(4):755-762. 10.1016/S0360-3016(98)00412-X, 10098430.
22. Hojris I, Overgaard M, Christensen JJ, Overgaard J. Morbidity and mortality of ischaemic heart disease in high-risk breast-cancer patients after adjuvant postmastectomy systemic treatment with or without radiotherapy: analysis of DBCG 82b and 82c randomised trials. Radiotherapy Committee of the Danish Breast Cancer Cooperative Group. Lancet 1999, 354(9188):1425-1430. 10.1016/S0140-6736(99)02245-X, 10543669.
23. Patt DA, Goodwin JS, Kuo YF, Freeman JL, Zhang DD, Buchholz TA, Hortobagyi GN, Giordano SH. Cardiac morbidity of adjuvant radiotherapy for breast cancer. J Clin Oncol 2005, 23(30):7475-7482. 10.1200/JCO.2005.13.755, 16157933.
24. Correa CR, Litt HI, Hwang WT, Ferrari VA, Solin LJ, Harris EE. Coronary artery findings after left-sided compared with right-sided radiation treatment for early-stage breast cancer. J Clin Oncol 2007, 25(21):3031-3037. 10.1200/JCO.2006.08.6595, 17634481.
25. Beckham WA, Popescu CC, Patenaude VV, Wai ES, Olivotto IA. Is multibeam IMRT better than standard treatment for patients with left-sided breast cancer?. Int J Radiat Oncol Biol Phys 2007, 69(3):918-924. 10.1016/j.ijrobp.2007.06.060, 17889273.
26. Dogan N, Cuttino L, Lloyd R, Bump EA, Arthur DW. Optimized dose coverage of regional lymph nodes in breast cancer: the role of intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 2007, 68(4):1238-1250. 10.1016/j.ijrobp.2007.03.059, 17512134.
27. Abo-Madyan Y, Polednik M, Rahn A, Schneider F, Dobler B, Wenz F, Lohr F. Improving dose homogeneity in large breasts by IMRT: efficacy and dosimetric accuracy of different techniques. Strahlenther Onkol 2008, 184(2):86-92. 10.1007/s00066-008-1730-9, 18259700.
28. Barnett GC, Wilkinson J, Moody AM, Wilson CB, Sharma R, Klager S, Hoole AC, Twyman N, Burnet NG, Coles CE. A randomised controlled trial of forward-planned radiotherapy (IMRT) for early breast cancer: baseline characteristics and dosimetry results. Radiother Oncol 2009, 92(1):34-41. 10.1016/j.radonc.2009.03.003, 19375808.
29. Caudrelier JM, Morgan SC, Montgomery L, Lacelle M, Nyiri B, Macpherson M. Helical tomotherapy for locoregional irradiation including the internal mammary chain in left-sided breast cancer: dosimetric evaluation. Radiother Oncol 2009, 90(1):99-105. 10.1016/j.radonc.2008.09.028, 18977546.
30. Cozzi L, Fogliata A, Nicolini G, Bernier J. Clinical experience in breast irradiation with intensity modulated photon beams. Acta Oncol 2005, 44(5):467-474. 10.1080/02841860510029879, 16118080.
31. Descovich M, Fowble B, Bevan A, Schechter N, Park C, Xia P. Comparison between hybrid direct aperture optimized intensity-modulated radiotherapy and forward planning intensity-modulated radiotherapy for whole breast irradiation. Int J Radiat Oncol Biol Phys 2010, 76(1):91-99. 10.1016/j.ijrobp.2009.01.011, 19395189.
32. Donovan E, Bleakley N, Denholm E, Evans P, Gothard L, Hanson J, Peckitt C, Reise S, Ross G, Sharp G, et al. Randomised trial of standard 2 D radiotherapy (RT) versus intensity modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy. Radiother Oncol 2007, 82(3):254-264. 10.1016/j.radonc.2006.12.008, 17224195.
33. Donovan EM, Yarnold JR, Adams EJ, Morgan A, Warrington AP, Evans PM. An investigation into methods of IMRT planning applied to breast radiotherapy. Br J Radiol 2008, 81(964):311-322. 10.1259/bjr/28583675, 18344275.
34. Fogliata A, Nicolini G, Alber M, Asell M, Dobler B, El-Haddad M, Hardemark B, Jelen U, Kania A, Larsson M, et al. IMRT for breast. a planning study. Radiother Oncol 2005, 76(3):300-310. 10.1016/j.radonc.2005.08.004, 16153730.
35. Harsolia A, Kestin L, Grills I, Wallace M, Jolly S, Jones C, Lala M, Martinez A, Schell S, Vicini FA. Intensity-modulated radiotherapy results in significant decrease in clinical toxicities compared with conventional wedge-based breast radiotherapy. Int J Radiat Oncol Biol Phys 2007, 68(5):1375-1380. 10.1016/j.ijrobp.2007.02.044, 17544598.
36. Herrick JS, Neill CJ, Rosser PF. A comprehensive clinical 3-dimensional dosimetric analysis of forward planned IMRT and conventional wedge planned techniques for intact breast radiotherapy. Med Dosim 2008, 33(1):62-70. 10.1016/j.meddos.2007.06.001, 18262125.
37. McDonald MW, Godette KD, Butker EK, Davis LW, Johnstone PA. Long-term outcomes of IMRT for breast cancer: a single-institution cohort analysis. Int J Radiat Oncol Biol Phys 2008, 72(4):1031-1040. 10.1016/j.ijrobp.2008.02.053, 18440727.
38. McDonald MW, Godette KD, Whitaker DJ, Davis LW, Johnstone PA. Three-Year Outcomes of Breast Intensity-Modulated Radiation Therapy with Simultaneous Integrated Boost. Int J Radiat Oncol Biol Phys 2009,
39. Moon SH, Shin KH, Kim TH, Yoon M, Park S, Lee DH, Kim JW, Kim DW, Park SY, Cho KH. Dosimetric comparison of four different external beam partial breast irradiation techniques: three-dimensional conformal radiotherapy, intensity-modulated radiotherapy, helical tomotherapy, and proton beam therapy. Radiother Oncol 2009, 90(1):66-73. 10.1016/j.radonc.2008.09.027, 18992950.
40. Morganti AG, Cilla S, Valentini V, Digesu C, Macchia G, Deodato F, Ferrandina G, Cece MG, Cirocco M, Garganese G, et al. Phase I-II studies on accelerated IMRT in breast carcinoma: technical comparison and acute toxicity in 332 patients. Radiother Oncol 2009, 90(1):86-92. 10.1016/j.radonc.2008.10.017, 19010560.
41. Popescu CC, Olivotto IA, Beckham WA, Ansbacher W, Zavgorodni S, Shaffer R, Wai ES, Otto K. Volumetric modulated arc therapy improves dosimetry and reduces treatment time compared to conventional intensity-modulated radiotherapy for locoregional radiotherapy of left-sided breast cancer and internal mammary nodes. Int J Radiat Oncol Biol Phys 2010, 76(1):287-295. 10.1016/j.ijrobp.2009.05.038, 19775832.
42. Remouchamps VM, Vicini FA, Sharpe MB, Kestin LL, Martinez AA, Wong JW. Significant reductions in heart and lung doses using deep inspiration breath hold with active breathing control and intensity-modulated radiation therapy for patients treated with locoregional breast irradiation. Int J Radiat Oncol Biol Phys 2003, 55(2):392-406. 10.1016/S0360-3016(02)04143-3, 12527053.
43. Thilmann C, Zabel A, Kuhn S, Bendl R, Rhein B, Wannenmacher M, Debus J. [Inversely planned intensity modulated radiotherapy for irradiation of a woman with breast cancer and funnel chest]. Strahlenther Onkol 2002, 178(11):637-643. 10.1007/s00066-002-0955-2, 12426675.
44. Fong A, Bromley R, Beat M, Vien D, Dineley J, Morgan G. Dosimetric comparison of intensity modulated radiotherapy techniques and standard wedged tangents for whole breast radiotherapy. J Med Imaging Radiat Oncol 2009, 53(1):92-99. 10.1111/j.1754-9485.2009.02043.x, 19453534.
45. Bhatnagar AK, Beriwal S, Heron DE, Flickinger JC, Deutsch M, Huq MS, Sontag M, Shogan J. Initial Outcomes Analysis for Large Multicenter Integrated Cancer Network Implementation of Intensity Modulated Radiation Therapy for Breast Cancer. Breast J 2009, 15(5):468-74. 10.1111/j.1524-4741.2009.00761.x, 19624420.
46. Bhatnagar AK, Brandner E, Sonnik D, Wu A, Kalnicki S, Deutsch M, Heron DE. Intensity modulated radiation therapy (IMRT) reduces the dose to the contralateral breast when compared to conventional tangential fields for primary breast irradiation. Breast Cancer Res Treat 2006, 96(1):41-46. 10.1007/s10549-005-9032-8, 16244787.
47. Bhatnagar AK, Heron DE, Deutsch M, Brandner E, Wu A, Kalnicki S. Does breast size affect the scatter dose to the ipsilateral lung, heart, or contralateral breast in primary breast irradiation using intensity-modulated radiation therapy (IMRT)?. Am J Clin Oncol 2006, 29(1):80-84. 10.1097/01.coc.0000198743.80991.15, 16462508.
48. Burmeister J, Alvarado N, Way S, McDermott P, Bossenberger T, Jaenisch H, Patel R, Washington T. Assessment and minimization of contralateral breast dose for conventional and intensity modulated breast radiotherapy. Med Dosim 2008, 33(1):6-13. 10.1016/j.meddos.2007.04.003, 18262117.
49. Cavey ML, Bayouth JE, Endres EJ, Pena JM, Colman M, Hatch S. Dosimetric comparison of conventional and forward-planned intensity-modulated techniques for comprehensive locoregional irradiation of post-mastectomy left breast cancers. Med Dosim 2005, 30(2):107-116. 10.1016/j.meddos.2005.02.002, 15922178.
50. Gauer T, Engel K, Kiesel A, Albers D, Rades D. Comparison of electron IMRT to helical photon IMRT and conventional photon irradiation for treatment of breast and chest wall tumours. Radiother Oncol 2010, 94(3):313-318. 10.1016/j.radonc.2009.12.037, 20116121.
51. van der Laan HP, Korevaar EW, Dolsma WV, Maduro JH, Langendijk JA. Minimising contralateral breast dose in post-mastectomy intensity-modulated radiotherapy by incorporating conformal electron irradiation. Radiother Oncol 2010, 94(2):235-240. 10.1016/j.radonc.2009.12.015, 20080312.
52. Smith W, Menon G, Wolfe N, Ploquin N, Trotter T, Pudney D. IMRT for the breast: a comparison of tangential planning techniques. Phys Med Biol 2010, 55(4):1231-1241. 10.1088/0031-9155/55/4/022, 20124651.
53. Lohr F, El-Haddad M, Dobler B, Grau R, Wertz HJ, Kraus-Tiefenbacher U, Steil V, Madyan YA, Wenz F. Potential effect of robust and simple IMRT approach for left-sided breast cancer on cardiac mortality. Int J Radiat Oncol Biol Phys 2009, 74(1):73-80. 10.1016/j.ijrobp.2008.07.018, 18973977.
54. Coon AB, Dickler A, Kirk MC, Liao Y, Shah AP, Strauss JB, Chen S, Turian J, Griem KL. Tomotherapy and Multifield Intensity-Modulated Radiotherapy Planning Reduce Cardiac Doses in Left-Sided Breast Cancer Patients with Unfavorable Cardiac Anatomy. Int J Radiat Oncol Biol Phys 2009,
55. Gagliardi G, Lax I, Soderstrom S, Gyenes G, Rutqvist LE. Prediction of excess risk of long-term cardiac mortality after radiotherapy of stage I breast cancer. Radiother Oncol 1998, 46(1):63-71. 10.1016/S0167-8140(97)00167-9, 9488129.
56. Brosius FC, Waller BF, Roberts WC. Radiation heart disease. Analysis of 16 young (aged 15 to 33 years) necropsy patients who received over 3,500 rads to the heart. Am J Med 1981, 70(3):519-530. 10.1016/0002-9343(81)90574-X, 6782873.
57. McGale P, Darby SC. Low doses of ionizing radiation and circulatory diseases: a systematic review of the published epidemiological evidence. Radiat Res 2005, 163(3):247-257. 10.1667/RR3314, 15733031.
58. Preston DL, Shimizu Y, Pierce DA, Suyama A, Mabuchi K. Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997. Radiat Res 2003, 160(4):381-407. 10.1667/RR3049, 12968934.
59. Shimizu Y, Pierce DA, Preston DL, Mabuchi K. Studies of the mortality of atomic bomb survivors. Report 12, part II. Noncancer mortality: 1950-1990. Radiat Res 1999, 152(4):374-389. 10.2307/3580222, 10477914.
60. Taylor CW, McGale P, Darby SC. Cardiac risks of breast-cancer radiotherapy: a contemporary view. Clin Oncol (R Coll Radiol) 2006, 18(3):236-246.
61. Senkus-Konefka E, Jassem J. Cardiovascular effects of breast cancer radiotherapy. Cancer Treat Rev 2007, 33(6):578-593. 10.1016/j.ctrv.2007.07.011, 17764850.
62. Darby SC, Cutter DJ, Boerma M, Constine LS, Fajardo LF, Kodama K, Mabuchi K, Marks LB, Mettler FA, Pierce LJ, et al. Radiation-related heart disease: current knowledge and future prospects. Int J Radiat Oncol Biol Phys 2010, 76(3):656-665. 10.1016/j.ijrobp.2009.09.064, 20159360.
63. Fisher B, Anderson S, Bryant J, Margolese RG, Deutsch M, Fisher ER, Jeong JH, Wolmark N. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 2002, 347(16):1233-1241. 10.1056/NEJMoa022152, 12393820.
64. Roychoudhuri R, Evans H, Robinson D, Moller H. Radiation-induced malignancies following radiotherapy for breast cancer. Br J Cancer 2004, 91(5):868-872. 2409877, 15292931.
65. Muren LP, Maurstad G, Hafslund R, Anker G, Dahl O. Cardiac and pulmonary doses and complication probabilities in standard and conformal tangential irradiation in conservative management of breast cancer. Radiother Oncol 2002, 62(2):173-183. 10.1016/S0167-8140(01)00468-6, 11937244.
66. van Dongen JA, Voogd AC, Fentiman IS, Legrand C, Sylvester RJ, Tong D, van der Schueren E, Helle PA, van Zijl K, Bartelink H. Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 trial. J Natl Cancer Inst 2000, 92(14):1143-1150. 10.1093/jnci/92.14.1143, 10904087.
67. Blichert-Toft M, Nielsen M, During M, Moller S, Rank F, Overgaard M, Mouridsen HT. Long-term results of breast conserving surgery vs. mastectomy for early stage invasive breast cancer: 20-year follow-up of the Danish randomized DBCG-82TM protocol. Acta Oncol 2008, 47(4):672-681. 10.1080/02841860801971439, 18465335.
68. Hall EJ, Wuu CS. Radiation-induced second cancers: the impact of 3D-CRT and IMRT. Int J Radiat Oncol Biol Phys 2003, 56(1):83-88. 10.1016/S0360-3016(03)00073-7, 12694826.