Does breast size affect the scatter dose to the ipsilateral lung, heart, or contralateral breast in primary breast irradiation using intensity-modulated radiation therapy (IMRT)?

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 29, Issue 1, 2006, Pages 80-84

  Bhatnagar, Ajay K ^a   Heron, Dwight E ^a   Deutsch, Melvin ^a   Brandner, Edward ^a   Wu, Andrew ^a   Kalnicki, Shalom ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Breast cancer; Contralateral breast dose; Intensity modulated radiotherapy

Indexed keywords

ARTICLE; BREAST CANCER; BREAST CARCINOMA; CANCER RADIOTHERAPY; CANCER SURGERY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; HEART SIZE; HISTOGRAM; HUMAN; HUMAN CELL; HUMAN TISSUE; INTENSITY MODULATED RADIATION THERAPY; MAJOR CLINICAL STUDY; PHOTON; THERMOLUMINESCENCE DOSIMETER; BREAST; BREAST TUMOR; CARCINOMA; CLINICAL TRIAL; HEART; HEMISPHERIC DOMINANCE; HISTOLOGY; LUNG; RADIATION DOSE FRACTIONATION; RADIATION EXPOSURE; RADIATION INJURY;

BREAST; BREAST NEOPLASMS; CARCINOMA; DOSE FRACTIONATION; FEMALE; FUNCTIONAL LATERALITY; HEART; HUMANS; LUNG; NEOPLASMS, RADIATION-INDUCED; PHOTONS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 33644859995     PISSN: 02773732     EISSN: 1537453X     Source Type: Journal    
DOI: 10.1097/01.coc.0000198743.80991.15     Document Type: Article

References (29)

1. American Cancer Society. Cancer Facts & Figures 2003. Atlanta, GA: American Cancer Society; 2003.
2. Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;347:1233-1241.
3. Veronesi U, Cascinelli N, Mariani L, et al. Twenty-year follow-up a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med. 2002;347:1227-1232.
4. NIH Consensus Conference. Treatment of early-stage breast cancer. JAMA. 1991;265:391-395.
5. Osteen RT, Karnell LH. The National Cancer Database Report on breast cancer. Cancer. 1994;73:1994-2000.
6. Lazovich D, Solomon CC, Thomas DB, et al. Breast conservation therapy in the United States following the 1990 National Institutes of Health Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma. Cancer. 1999;86:628-637.
7. Land CE, Boice JD Jr, Shore RE, et al. Breast cancer risk from low-dose exposure to ionizing radiation: results of parallel analysis of three exposed populations of women. J Natl Cancer Inst. 1980;65:353-376.
8. Kwa SLS, Lebesque JV, Theuws JCM, et al. Radiation pneumonitis as a function of mean lung dose: an analysis of pooled data of 540 patients. Int J Radiat Oncol Biol Phys. 1998;42:1-9.
9. Hurkmann CW, Borger JH, Bos LJ, et al. Cardiac and lung complication probabilities after breast cancer irradiation. Radiother Oncol. 2000;55:145-151.
10. Boice JD Jr, Harvey EB, Blettner M, et al. Cancer in the contralateral breast after radiotherapy for breast cancer. N Engl J Med. 1992;326:781-785.
11. Obedian E, Fischer DB, Hafty BG. Second malignancies after treatment of early-stage breast cancer: lumpectomy and radiation therapy versus mastectomy. J Clin Oncol. 2000;18:2406-2412.
12. Fraass BA, Roberson PL, Lichter AS. Dose to the contralateral breast due to primary breast irradiation. Int J Radiat Oncol Biol Phys. 1985;11:485-497.
13. Early Breast Cancer Trialists Collaborative Group. Favorable and unfavorable effects on long term survival of radiotherapy for early breast cancer: an overview of the randomized trials. Lancet. 2000;355:1757-1770.
14. Paszat L, MacKillop W, Groome P, et al. Mortality from myocardial infarction following postlumpectomy radiotherapy for breast cancer: a population based study in Ontario, Canada. Int J Radiat Oncol Biol Phys. 1999;43:755-762.
15. Das IJ, Cheng EC, Freedman G, et al. Lung and heart dose volume analyses with CT simulator in radiation treatment of breast cancer. Int J Radiat Oncol Biol Phys. 1998;42:11-19.
16. Shapiro CL, Recht A. Side effects of adjuvant treatment of breast cancer. N Engl J Med. 2001;344:1997-2008.
17. Zelefsky MJ, Fuks Z, Hunt M, et al. High-dose intensity modulated radiation therapy for prostate cancer: early toxicity and biochemical outcome in 772 patients. Int J Radiat Oncol Biol Phys. 2002;53:1111-1116.
18. Heron DE, Gerszten K, Selvaraj RN, et al. Conventional 3D conformal versus intensity-modulated radiotherapy for the adjuvant treatment of gynecologic malignancies: a comparative dosimetric study of dose-volume histograms. Gynecol Oncol. 2003;91:39-45.
19. Remouchamps VM, Vicini FA, Sharpe MB, et al. Significant reductions in heart and lung doses using deep inspiration breath hold with active breathing control and intensity-modulated radiation therapy for patients treated with locoregional breast irradiation. Int J Radiat Oncol Biol Phys. 2003;55:392-406.
20. Hong L, Hunt M, Chui C, et al. Intensity-modulated tangential beam irradiation of the intact breast. Int J Radiat Oncol Biol Phys. 1999;44:1155-1164.
21. Krueger EA, Fraass BA, Pierce LJ. Clinical aspects of intensity-modulated radiotherapy in the treatment of breast cancer. Semin Radiat Oncol. 2002;12:250-259.
22. Landau D, Adams EJ, Webb S, et al. Cardiac avoidance in breast radiotherapy: a comparison of simple shielding techniques with intensity-modulated radiotherapy. Radiother Oncol. 2001;60:247-255.
23. Chang SX, Deschesne KM, Cullip TJ, et al. A comparison of different intensity modulation treatment techniques for tangential breast irradiation. Int J Radiat Oncol Biol Phys. 1999;45:1305-1314.
24. Kestin LL, Sharpe MB, Frazier RC, et al. Intensity modulation to improve dose uniformity with tangential breast radiotherapy: initial clinical experience. Int J Radiat Oncol Biol Phys. 2000;48:1559-1568.
25. Bhatnagar AK, Brandner E, Sonnik D, et al. Intensity modulated radiation therapy (IMRT) significantly reduced the dose to the contralateral breast when compared to conventional tangential fields for primary breast irradiation: initial report. Cancer J. 2004;10:381-385.
26. Bhatnagar AK, Brandner E, Sonnick D. Intensity modulated radiation therapy (IMRT) reduced the dose to the contralateral breast when compared to the conventional tangential fields for primary breast irradiation. Breast Cancer Res Treat. 2005;1-6.
27. Moody AM, Mayles WPM, Bliss JM, et al. The influence of breast size on late radiation effects and association with radiotherapy dose inhomogeneity. Radiother Oncol. 1994;33:106-112.
28. Neal AJ, Torr M, Helyer S, et al. Correlation of breast dose homogeneity with breast size using 3D CT planning and dose volume histograms. Radiother Oncol. 1995;34:210-218.
29. Vicini FA, Sharpe M, Kestin L, et al. Optimizing breast cancer treatment efficacy with intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys. 2002;54:1336-1344.