메뉴 건너뛰기




Volumn 9, Issue , 2011, Pages

High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area

Author keywords

ERCC1, squamous cell carcinoma of head and neck, betel nuts, induction chemotherapy, chemoradiation

Indexed keywords

CISPLATIN; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; FLUOROURACIL; DNA BINDING PROTEIN; ENDONUCLEASE; ERCC1 PROTEIN, HUMAN;

EID: 79953089755     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-9-31     Document Type: Article
Times cited : (44)

References (42)
  • 2
    • 0036250933 scopus 로고    scopus 로고
    • Novel therapeutics for head and neck cancer
    • 10.1097/00001622-200205000-00014, 11981281
    • Kim ES, Kies M, Herbst RS. Novel therapeutics for head and neck cancer. Curr Opin Oncol 2002, 14:334-342. 10.1097/00001622-200205000-00014, 11981281.
    • (2002) Curr Opin Oncol , vol.14 , pp. 334-342
    • Kim, E.S.1    Kies, M.2    Herbst, R.S.3
  • 3
    • 68949209288 scopus 로고    scopus 로고
    • Comprehensive study on the prognostic role of osteopontin expression in oral squamous cell carcinoma
    • 10.1016/j.oraloncology.2008.12.006, 19213594
    • Chien CY, Su CY, Chuang HC, Fang FM, Huang HY, Chen CH, Chen CM, Huang CC. Comprehensive study on the prognostic role of osteopontin expression in oral squamous cell carcinoma. Oral Oncol 2009, 45:798-802. 10.1016/j.oraloncology.2008.12.006, 19213594.
    • (2009) Oral Oncol , vol.45 , pp. 798-802
    • Chien, C.Y.1    Su, C.Y.2    Chuang, H.C.3    Fang, F.M.4    Huang, H.Y.5    Chen, C.H.6    Chen, C.M.7    Huang, C.C.8
  • 4
    • 79953732814 scopus 로고    scopus 로고
    • Cancer Registry Annual Report in Taiwan Area. Taipei
    • Department of Health EY, R.O.C.
    • Department of Health EY, R.O.C. Cancer Registry Annual Report in Taiwan Area. Taipei. Department of Health, Executive Yuan, ROC 2006, Department of Health EY, R.O.C..
    • (2006) Department of Health, Executive Yuan, ROC
  • 5
    • 0029394950 scopus 로고
    • Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan
    • 10.1111/j.1600-0714.1995.tb01132.x, 8600280
    • Ko YC, Huang YL, Lee CH, Chen MJ, Lin LM, Tsai CC. Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan. J Oral Pathol Med 1995, 24:450-453. 10.1111/j.1600-0714.1995.tb01132.x, 8600280.
    • (1995) J Oral Pathol Med , vol.24 , pp. 450-453
    • Ko, Y.C.1    Huang, Y.L.2    Lee, C.H.3    Chen, M.J.4    Lin, L.M.5    Tsai, C.C.6
  • 6
    • 0034801362 scopus 로고    scopus 로고
    • Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese
    • 10.1093/carcin/22.9.1497, 11532872
    • Hsieh LL, Wang PF, Chen IH, Liao CT, Wang HM, Chen MC, Chang JT, Cheng AJ. Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese. Carcinogenesis 2001, 22:1497-1503. 10.1093/carcin/22.9.1497, 11532872.
    • (2001) Carcinogenesis , vol.22 , pp. 1497-1503
    • Hsieh, L.L.1    Wang, P.F.2    Chen, I.H.3    Liao, C.T.4    Wang, H.M.5    Chen, M.C.6    Chang, J.T.7    Cheng, A.J.8
  • 7
    • 0037208591 scopus 로고    scopus 로고
    • An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer
    • 10.1200/JCO.2003.01.008, 12506176
    • Adelstein DJ, Li Y, Adams GL, Wagner H, Kish JA, Ensley JF, Schuller DE, Forastiere AA. An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer. J Clin Oncol 2003, 21:92-98. 10.1200/JCO.2003.01.008, 12506176.
    • (2003) J Clin Oncol , vol.21 , pp. 92-98
    • Adelstein, D.J.1    Li, Y.2    Adams, G.L.3    Wagner, H.4    Kish, J.A.5    Ensley, J.F.6    Schuller, D.E.7    Forastiere, A.A.8
  • 8
    • 33847344521 scopus 로고    scopus 로고
    • Long-term results of Intergroup RTOG 91-11: a phase III trial to preserve the larynx -- induction cisplatin/5-FU and radiation therapy versus concurrent cisplatin and radiation therapy versus radiation therapy
    • abstract
    • Forastiere AAMM, Weber RS, et al. Long-term results of Intergroup RTOG 91-11: a phase III trial to preserve the larynx -- induction cisplatin/5-FU and radiation therapy versus concurrent cisplatin and radiation therapy versus radiation therapy. J Clin Oncol 2006, 24(Suppl):284s. abstract.
    • (2006) J Clin Oncol , vol.24 , Issue.SUPPL
    • Forastiere, A.A.M.M.1    Weber, R.S.2
  • 11
    • 0036256065 scopus 로고    scopus 로고
    • Update on chemoradiotherapy for head and neck cancer
    • 10.1097/00001622-200205000-00012, 11981279
    • Argiris A. Update on chemoradiotherapy for head and neck cancer. Curr Opin Oncol 2002, 14:323-329. 10.1097/00001622-200205000-00012, 11981279.
    • (2002) Curr Opin Oncol , vol.14 , pp. 323-329
    • Argiris, A.1
  • 12
    • 0034681783 scopus 로고    scopus 로고
    • Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer
    • Pignon JP, Bourhis J, Domenge C, Designe L. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet 2000, 355:949-955.
    • (2000) Lancet , vol.355 , pp. 949-955
    • Pignon, J.P.1    Bourhis, J.2    Domenge, C.3    Designe, L.4
  • 14
    • 0027982841 scopus 로고
    • Phase III trial of initial chemotherapy in stage III or IV head and neck cancers: a study by the Gruppo di Studio sui Tumori della Testa e del Collo
    • 10.1093/jnci/86.4.265, 8158680
    • Paccagnella A, Orlando A, Marchiori C, Zorat PL, Cavaniglia G, Sileni VC, Jirillo A, Tomio L, Fila G, Fede A, et al. Phase III trial of initial chemotherapy in stage III or IV head and neck cancers: a study by the Gruppo di Studio sui Tumori della Testa e del Collo. J Natl Cancer Inst 1994, 86:265-272. 10.1093/jnci/86.4.265, 8158680.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 265-272
    • Paccagnella, A.1    Orlando, A.2    Marchiori, C.3    Zorat, P.L.4    Cavaniglia, G.5    Sileni, V.C.6    Jirillo, A.7    Tomio, L.8    Fila, G.9    Fede, A.10
  • 15
    • 0028141961 scopus 로고
    • Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy
    • 10.1172/JCI117388, 296149, 8040325
    • Dabholkar M, Vionnet J, Bostick-Bruton F, Yu JJ, Reed E. Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy. J Clin Invest 1994, 94:703-708. 10.1172/JCI117388, 296149, 8040325.
    • (1994) J Clin Invest , vol.94 , pp. 703-708
    • Dabholkar, M.1    Vionnet, J.2    Bostick-Bruton, F.3    Yu, J.J.4    Reed, E.5
  • 16
    • 0030566883 scopus 로고    scopus 로고
    • The importance of the ERCC1/ERCC4[XPF] complex for hypoxic-cell radioresistance does not appear to derive from its participation in the nucleotide excision repair pathway
    • Murray D, Rosenberg E. The importance of the ERCC1/ERCC4[XPF] complex for hypoxic-cell radioresistance does not appear to derive from its participation in the nucleotide excision repair pathway. Mutat Res 1996, 364:217-226.
    • (1996) Mutat Res , vol.364 , pp. 217-226
    • Murray, D.1    Rosenberg, E.2
  • 18
    • 33847645479 scopus 로고    scopus 로고
    • Prognostic value of expression of ERCC1, thymidylate synthase, and glutathione S-transferase P1 for 5-fluorouracil/oxaliplatin chemotherapy in advanced gastric cancer
    • 10.1093/annonc/mdl430, 17322540
    • Kwon HC, Roh MS, Oh SY, Kim SH, Kim MC, Kim JS, Kim HJ. Prognostic value of expression of ERCC1, thymidylate synthase, and glutathione S-transferase P1 for 5-fluorouracil/oxaliplatin chemotherapy in advanced gastric cancer. Ann Oncol 2007, 18:504-509. 10.1093/annonc/mdl430, 17322540.
    • (2007) Ann Oncol , vol.18 , pp. 504-509
    • Kwon, H.C.1    Roh, M.S.2    Oh, S.Y.3    Kim, S.H.4    Kim, M.C.5    Kim, J.S.6    Kim, H.J.7
  • 19
    • 17044428615 scopus 로고    scopus 로고
    • High gene expression of TS1, GSTP1, and ERCC1 are risk factors for survival in patients treated with trimodality therapy for esophageal cancer
    • 10.1158/1078-0432.CCR-04-1387, 15788669
    • Joshi MB, Shirota Y, Danenberg KD, Conlon DH, Salonga DS, Herndon JE, Danenberg PV, Harpole DH. High gene expression of TS1, GSTP1, and ERCC1 are risk factors for survival in patients treated with trimodality therapy for esophageal cancer. Clin Cancer Res 2005, 11:2215-2221. 10.1158/1078-0432.CCR-04-1387, 15788669.
    • (2005) Clin Cancer Res , vol.11 , pp. 2215-2221
    • Joshi, M.B.1    Shirota, Y.2    Danenberg, K.D.3    Conlon, D.H.4    Salonga, D.S.5    Herndon, J.E.6    Danenberg, P.V.7    Harpole, D.H.8
  • 20
    • 0031982522 scopus 로고    scopus 로고
    • ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy
    • Metzger R, Leichman CG, Danenberg KD, Danenberg PV, Lenz HJ, Hayashi K, Groshen S, Salonga D, Cohen H, Laine L, et al. ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy. J Clin Oncol 1998, 16:309-316.
    • (1998) J Clin Oncol , vol.16 , pp. 309-316
    • Metzger, R.1    Leichman, C.G.2    Danenberg, K.D.3    Danenberg, P.V.4    Lenz, H.J.5    Hayashi, K.6    Groshen, S.7    Salonga, D.8    Cohen, H.9    Laine, L.10
  • 23
    • 34447258350 scopus 로고    scopus 로고
    • The synergistic effect of cigarette taxes on the consumption of cigarettes, alcohol and betel nuts
    • 10.1186/1471-2458-7-121, 1913507, 17592627
    • Lee JM. The synergistic effect of cigarette taxes on the consumption of cigarettes, alcohol and betel nuts. BMC Public Health 2007, 7:121. 10.1186/1471-2458-7-121, 1913507, 17592627.
    • (2007) BMC Public Health , vol.7 , pp. 121
    • Lee, J.M.1
  • 24
    • 33846965212 scopus 로고    scopus 로고
    • Betel quid not containing tobacco and oral cancer: a report on a case-control study in Papua New Guinea and a meta-analysis of current evidence
    • 10.1002/ijc.22304, 17163423
    • Thomas SJ, Bain CJ, Battistutta D, Ness AR, Paissat D, Maclennan R. Betel quid not containing tobacco and oral cancer: a report on a case-control study in Papua New Guinea and a meta-analysis of current evidence. Int J Cancer 2007, 120:1318-1323. 10.1002/ijc.22304, 17163423.
    • (2007) Int J Cancer , vol.120 , pp. 1318-1323
    • Thomas, S.J.1    Bain, C.J.2    Battistutta, D.3    Ness, A.R.4    Paissat, D.5    Maclennan, R.6
  • 25
    • 3543128313 scopus 로고    scopus 로고
    • Alert for an epidemic of oral cancer due to use of the betel quid substitutes gutkha and pan masala: a review of agents and causative mechanisms
    • 10.1093/mutage/geh036, 15215323
    • Nair U, Bartsch H, Nair J. Alert for an epidemic of oral cancer due to use of the betel quid substitutes gutkha and pan masala: a review of agents and causative mechanisms. Mutagenesis 2004, 19:251-262. 10.1093/mutage/geh036, 15215323.
    • (2004) Mutagenesis , vol.19 , pp. 251-262
    • Nair, U.1    Bartsch, H.2    Nair, J.3
  • 26
    • 39149095593 scopus 로고    scopus 로고
    • Association of epidermal growth factor receptor (EGFR) gene copy number amplification with neck lymph node metastasis in areca-associated oral carcinomas
    • 10.1016/j.oraloncology.2007.02.008, 17468034
    • Chiang WF, Liu SY, Yen CY, Lin CN, Chen YC, Lin SC, Chang KW. Association of epidermal growth factor receptor (EGFR) gene copy number amplification with neck lymph node metastasis in areca-associated oral carcinomas. Oral Oncol 2008, 44:270-276. 10.1016/j.oraloncology.2007.02.008, 17468034.
    • (2008) Oral Oncol , vol.44 , pp. 270-276
    • Chiang, W.F.1    Liu, S.Y.2    Yen, C.Y.3    Lin, C.N.4    Chen, Y.C.5    Lin, S.C.6    Chang, K.W.7
  • 27
    • 0041733629 scopus 로고    scopus 로고
    • Prognostic significance of EGFR and Her-2 in oral cavity cancer in betel quid prevalent area cancer prognosis
    • 10.1038/sj.bjc.6601171, 2376917, 12915878
    • Chen IH, Chang JT, Liao CT, Wang HM, Hsieh LL, Cheng AJ. Prognostic significance of EGFR and Her-2 in oral cavity cancer in betel quid prevalent area cancer prognosis. Br J Cancer 2003, 89:681-686. 10.1038/sj.bjc.6601171, 2376917, 12915878.
    • (2003) Br J Cancer , vol.89 , pp. 681-686
    • Chen, I.H.1    Chang, J.T.2    Liao, C.T.3    Wang, H.M.4    Hsieh, L.L.5    Cheng, A.J.6
  • 28
    • 34447126864 scopus 로고    scopus 로고
    • Excision repair cross complementation group 1 immunohistochemical expression predicts objective response and cancer-specific survival in patients treated by Cisplatin-based induction chemotherapy for locally advanced head and neck squamous cell carcinoma
    • 10.1158/1078-0432.CCR-07-0252, 17606717
    • Handra-Luca A, Hernandez J, Mountzios G, Taranchon E, Lacau-St-Guily J, Soria JC, Fouret P. Excision repair cross complementation group 1 immunohistochemical expression predicts objective response and cancer-specific survival in patients treated by Cisplatin-based induction chemotherapy for locally advanced head and neck squamous cell carcinoma. Clin Cancer Res 2007, 13:3855-3859. 10.1158/1078-0432.CCR-07-0252, 17606717.
    • (2007) Clin Cancer Res , vol.13 , pp. 3855-3859
    • Handra-Luca, A.1    Hernandez, J.2    Mountzios, G.3    Taranchon, E.4    Lacau-St-Guily, J.5    Soria, J.C.6    Fouret, P.7
  • 29
    • 46349110628 scopus 로고    scopus 로고
    • ERCC1 expression as a predictive marker of squamous cell carcinoma of the head and neck treated with cisplatin-based concurrent chemoradiation
    • 10.1038/sj.bjc.6604464, 2453006, 18594541
    • Jun HJ, Ahn MJ, Kim HS, Yi SY, Han J, Lee SK, Ahn YC, Jeong HS, Son YI, Baek JH, Park K. ERCC1 expression as a predictive marker of squamous cell carcinoma of the head and neck treated with cisplatin-based concurrent chemoradiation. Br J Cancer 2008, 99:167-172. 10.1038/sj.bjc.6604464, 2453006, 18594541.
    • (2008) Br J Cancer , vol.99 , pp. 167-172
    • Jun, H.J.1    Ahn, M.J.2    Kim, H.S.3    Yi, S.Y.4    Han, J.5    Lee, S.K.6    Ahn, Y.C.7    Jeong, H.S.8    Son, Y.I.9    Baek, J.H.10    Park, K.11
  • 31
    • 48249135539 scopus 로고    scopus 로고
    • Patients with ERCC1-negative locally advanced esophageal cancers may benefit from preoperative chemoradiotherapy
    • 10.1158/1078-0432.CCR-07-4848, 18594004
    • Kim MK, Cho KJ, Kwon GY, Park SI, Kim YH, Kim JH, Song HY, Shin JH, Jung HY, Lee GH, et al. Patients with ERCC1-negative locally advanced esophageal cancers may benefit from preoperative chemoradiotherapy. Clin Cancer Res 2008, 14:4225-4231. 10.1158/1078-0432.CCR-07-4848, 18594004.
    • (2008) Clin Cancer Res , vol.14 , pp. 4225-4231
    • Kim, M.K.1    Cho, K.J.2    Kwon, G.Y.3    Park, S.I.4    Kim, Y.H.5    Kim, J.H.6    Song, H.Y.7    Shin, J.H.8    Jung, H.Y.9    Lee, G.H.10
  • 32
    • 75449105597 scopus 로고    scopus 로고
    • MMP9 but Not EGFR, MET, ERCC1, P16, and P-53 Is Associated with Response to Concomitant Radiotherapy, Cetuximab, and Weekly Cisplatin in Patients with Locally Advanced Head and Neck Cancer
    • 2801452, 20066159
    • Fountzilas G, Kalogera-Fountzila A, Lambaki S, Wirtz RM, Nikolaou A, Karayannopoulou G, Bobos M, Kotoula V, Murray S, Lambropoulos A, et al. MMP9 but Not EGFR, MET, ERCC1, P16, and P-53 Is Associated with Response to Concomitant Radiotherapy, Cetuximab, and Weekly Cisplatin in Patients with Locally Advanced Head and Neck Cancer. J Oncol 2009, 2009:305908. 2801452, 20066159.
    • (2009) J Oncol , vol.2009 , pp. 305908
    • Fountzilas, G.1    Kalogera-Fountzila, A.2    Lambaki, S.3    Wirtz, R.M.4    Nikolaou, A.5    Karayannopoulou, G.6    Bobos, M.7    Kotoula, V.8    Murray, S.9    Lambropoulos, A.10
  • 33
    • 33748430003 scopus 로고    scopus 로고
    • Expression of XRCC1 and ERCC1 proteins in radioresistant and radiosensitive laryngeal cancer
    • Nix PG, Stafford N, Cawkwell L. Expression of XRCC1 and ERCC1 proteins in radioresistant and radiosensitive laryngeal cancer. Cancer Therapy 2004, 2:47-53.
    • (2004) Cancer Therapy , vol.2 , pp. 47-53
    • Nix, P.G.1    Stafford, N.2    Cawkwell, L.3
  • 34
    • 0033561522 scopus 로고    scopus 로고
    • Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck
    • Huang SM, Bock JM, Harari PM. Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck. Cancer Res 1999, 59:1935-1940.
    • (1999) Cancer Res , vol.59 , pp. 1935-1940
    • Huang, S.M.1    Bock, J.M.2    Harari, P.M.3
  • 35
    • 0034084314 scopus 로고    scopus 로고
    • Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis
    • Huang SM, Harari PM. Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin Cancer Res 2000, 6:2166-2174.
    • (2000) Clin Cancer Res , vol.6 , pp. 2166-2174
    • Huang, S.M.1    Harari, P.M.2
  • 36
    • 33750357154 scopus 로고    scopus 로고
    • Integration of EGFR inhibitors with radiochemotherapy
    • 10.1038/nrc1953, 17036041
    • Nyati MK, Morgan MA, Feng FY, Lawrence TS. Integration of EGFR inhibitors with radiochemotherapy. Nat Rev Cancer 2006, 6:876-885. 10.1038/nrc1953, 17036041.
    • (2006) Nat Rev Cancer , vol.6 , pp. 876-885
    • Nyati, M.K.1    Morgan, M.A.2    Feng, F.Y.3    Lawrence, T.S.4
  • 37
    • 40249109168 scopus 로고    scopus 로고
    • Activation of protein kinase Cepsilon stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation
    • 10.1016/j.radonc.2007.10.041, 18037521
    • Wanner G, Mayer C, Kehlbach R, Rodemann HP, Dittmann K. Activation of protein kinase Cepsilon stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation. Radiother Oncol 2008, 86:383-390. 10.1016/j.radonc.2007.10.041, 18037521.
    • (2008) Radiother Oncol , vol.86 , pp. 383-390
    • Wanner, G.1    Mayer, C.2    Kehlbach, R.3    Rodemann, H.P.4    Dittmann, K.5
  • 38
    • 37049038610 scopus 로고    scopus 로고
    • Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism
    • 10.1016/j.ijrobp.2007.08.065, 17996386
    • Dittmann KH, Mayer C, Ohneseit PA, Raju U, Andratschke NH, Milas L, Rodemann HP. Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism. Int J Radiat Oncol Biol Phys 2008, 70:203-212. 10.1016/j.ijrobp.2007.08.065, 17996386.
    • (2008) Int J Radiat Oncol Biol Phys , vol.70 , pp. 203-212
    • Dittmann, K.H.1    Mayer, C.2    Ohneseit, P.A.3    Raju, U.4    Andratschke, N.H.5    Milas, L.6    Rodemann, H.P.7
  • 40
    • 33846404174 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance and toxicity associated with platinating agents
    • 10.1016/j.ctrv.2006.09.006, 1855222, 17084534
    • Rabik CA, Dolan ME. Molecular mechanisms of resistance and toxicity associated with platinating agents. Cancer Treat Rev 2007, 33:9-23. 10.1016/j.ctrv.2006.09.006, 1855222, 17084534.
    • (2007) Cancer Treat Rev , vol.33 , pp. 9-23
    • Rabik, C.A.1    Dolan, M.E.2
  • 41
    • 38049045220 scopus 로고    scopus 로고
    • Cetuximab potentiates oxaliplatin cytotoxic effect through a defect in NER and DNA replication initiation
    • 10.1038/sj.bjc.6604134, 2359709, 18182978
    • Balin-Gauthier D, Delord JP, Pillaire MJ, Rochaix P, Hoffman JS, Bugat R, Cazaux C, Canal P, Allal BC. Cetuximab potentiates oxaliplatin cytotoxic effect through a defect in NER and DNA replication initiation. Br J Cancer 2008, 98:120-128. 10.1038/sj.bjc.6604134, 2359709, 18182978.
    • (2008) Br J Cancer , vol.98 , pp. 120-128
    • Balin-Gauthier, D.1    Delord, J.P.2    Pillaire, M.J.3    Rochaix, P.4    Hoffman, J.S.5    Bugat, R.6    Cazaux, C.7    Canal, P.8    Allal, B.C.9
  • 42
    • 37549007196 scopus 로고    scopus 로고
    • Tumors established with cell lines selected for oxaliplatin resistance respond to oxaliplatin if combined with cetuximab
    • 10.1158/1078-0432.CCR-07-1768, 18094427
    • Prewett M, Deevi DS, Bassi R, Fan F, Ellis LM, Hicklin DJ, Tonra JR. Tumors established with cell lines selected for oxaliplatin resistance respond to oxaliplatin if combined with cetuximab. Clin Cancer Res 2007, 13:7432-7440. 10.1158/1078-0432.CCR-07-1768, 18094427.
    • (2007) Clin Cancer Res , vol.13 , pp. 7432-7440
    • Prewett, M.1    Deevi, D.S.2    Bassi, R.3    Fan, F.4    Ellis, L.M.5    Hicklin, D.J.6    Tonra, J.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.